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flumioxazin
N-(7-Fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2H-1,4-benzoxazin-6-yl)cyclohexene-1,2-dicarboximide

Supplier Sponsors

CAS Number: 103361-09-7Picture of molecule3D/inchi
Other(deleted CASRN):141490-50-8
FDA UNII: L0PX7OGI22
Nikkaji Web:J664.809F
MDL:MFCD01754256
XlogP3-AA:1.80 (est)
Molecular Weight:354.33775320
Formula:C19 H15 F N2 O4
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:herbicides / pesticides
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 202.50 °C. @ 760.00 mm Hg
Boiling Point: 644.43 °C. @ 760.00 mm Hg (est)
Vapor Pressure:2.410000 mmHg @ 2.41 °C. (est)
Flash Point: 650.00 °F. TCC ( 343.50 °C. ) (est)
logP (o/w): 2.550
Soluble in:
 water, 1.79 mg/L @ 25 °C (exp)
 water, 38.74 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
Flumioxazin 95%
Odor: characteristic
Use: Herbicide.
Carbosynth
For experimental / research use only.
Flumioxazin
Sigma-Aldrich
For experimental / research use only.
Flumioxazin PESTANAL®, analytical standard
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
herbicides / pesticides
Recommendation for flumioxazin usage levels up to:
 not for fragrance use.
 
Recommendation for flumioxazin flavor usage levels up to:
 not for flavor use.
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Reasoned opinion on the review of the existing maximum residue levels (MRLs) for flumioxazin according to Article 12 of Regulation (EC) No 396/2005
View page or View pdf

Conclusion on the peer review of the pesticide risk assessment of the active substance flumioxazin
View page or View pdf

Evaluation of data concerning the necessity of flumioxazin as a herbicide to control a serious danger to plant health which cannot be contained by other available means, including non-chemical methods
View page or View pdf

Peer review of the pesticide risk assessment for the active substance flumioxazin in light of negligible exposure data submitted
View page or View pdf

Updated peer review of the pesticide risk assessment of the active substance flumioxazin
View page or View pdf

EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :92425
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
2-(7-fluoro-3-oxo-4-prop-2-ynyl-1,4-benzoxazin-6-yl)-4,5,6,7-tetrahydroisoindole-1,3-dione
Chemidplus:0103361097
 
References:
 2-(7-fluoro-3-oxo-4-prop-2-ynyl-1,4-benzoxazin-6-yl)-4,5,6,7-tetrahydroisoindole-1,3-dione
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):92425
Pubchem (sid):135048700
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C11035
HMDB (The Human Metabolome Database):HMDB34854
FooDB:FDB013420
ChemSpider:View
Wikipedia:View
Formulations/Preparations:
•usepaopp pesticide code 129034; trade names: v-53482. •97.9% technical grade; 51% emulsifiable concentrate end-use product •wettable powder
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
2-[7-fluoro-3-oxo-4-(2-propyn-1-yl)-3,4-dihydro-2H-1,4-benzoxazin-6-yl]-4,5,6,7-tetrahydro-1H-isoindole-1,3(2H)-dione
2-[7-fluoro-3-oxo-4-(2-propyn-1-yl)-3,4-dihydro-2H-1,4-benzoxazin-6-yl]-4,5,6,7-tétrahydro-1H-isoindole-1,3(2H)-dione
2-[7-fluoro-3-oxo-4-(prop-2-yn-1-yl)-3,4-dihydro-2H-1,4-benzoxazin-6-yl]-4,5,6,7-tetrahydro-1H-isoindole-1,3(2H)-dione
2-(7-fluoro-3-oxo-4-prop-2-yn-1-yl-3,4-dihydro-2H-1,4-benzoxazin-6-yl)-4,5,6,7-tetrahydro-1H-isoindole-1,3(2H)-dione
2-(7-fluoro-3-oxo-4-prop-2-ynyl-1,4-benzoxazin-6-yl)-4,5,6,7-tetrahydroisoindole-1,3-dione
2-[7-fluoro-3,4-dihydro-3-oxo-4-(2-propynyl)-2H-1,4-benzoxazin-6-yl]-4,5,6,7-tetrahydro-1H-isoindole-1,3(2H)-dione
N-(7-Fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2H-1,4-benzoxazin-6-yl)cyclohexene-1,2-dicarboximide
1H-isoindole-1,3(2H)-dione, 2-[7-fluoro-3,4-dihydro-3-oxo-4-(2-propyn-1-yl)-2H-1,4-benzoxazin-6-yl]-4,5,6,7-tetrahydro-
1H-isoindole-1,3(2H)-dione, 2-[7-fluoro-3,4-dihydro-3-oxo-4-(2-propynyl)-2H-1,4-benzoxazin-6-yl]-4,5,6,7-tetrahydro-
 

Articles:

PubMed:Metabolism and physiologically based pharmacokinetic modeling of flumioxazin in pregnant animals.
PubMed:Novel colorimetric molecular switch based on copper(I)-catalyzed azide-alkyne cycloaddition reaction and its application for flumioxazin detection.
PubMed:A chemical approach for the mitigation of Prymnesium parvum blooms.
PubMed:Degradation of flumioxazin in illuminated water-sediment systems.
PubMed:Synthesis and herbicidal activity of isoindoline-1,3-dione substituted benzoxazinone derivatives containing a carboxylic ester group.
PubMed:Protoporphyrinogen oxidase inhibitor herbicide effects on pythium root rot of sugarcane, pythium species, and the soil microbial community.
PubMed:[Determination of flumioxazin residue in foods using gas chromatography-mass spectrometry].
PubMed:The herbicide flumioxazin stimulates pathogenesis-related gene expression and enzyme activities in Vitis vinifera.
PubMed:Dissipation and movement of flumioxazin in soil at four field sites in Chile.
PubMed:Evaluation of six pesticides leaching indexes using field data of herbicide application in Casablanca Valley, Chile.
PubMed:Chemical cotton stalk destruction for maintenance of host-free periods for the control of overwintering boll weevil in tropical and subtropical climates.
PubMed:Effect of the herbicide flumioxazin on photosynthetic performance of grapevine (Vitis vinifera L.).
PubMed:Vegetative reproduction and chemical control with post-emergent herbicides of field bindweed (Convolvulus arvensis L.).
PubMed:Weed control in sunflower (helianthus annuus L.) with post-emergent herbicides.
PubMed:Proteomic analysis of grapevine (Vitis vinifera L.) tissues subjected to herbicide stress.
PubMed:Synthesis and herbicidal activity of 2-(7-fluoro-3-oxo- 3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)isoindoline-1,3-diones.
PubMed:Sorption and desorption of flumioxazin to soil, clay minerals and ion-exchange resin.
PubMed:Hydrolysis and photolysis of flumioxazin in aqueous buffer solutions.
PubMed:Comparison of different physiological parameter responses in Lemna minor and Scenedesmus obliquus exposed to herbicide flumioxazin.
PubMed:Gas chromatographic/mass spectrometric determination of flumioxazin extracted from soil and water.
PubMed:Flumioxazin soil persistence and mineralization in laboratory experiments.
PubMed:Stress reactions in Vitis vinifera L. following soil application of the herbicide flumioxazin.
PubMed:Effects of flumioxazin herbicide on carbon nutrition of Vitis vinifera L.
PubMed:Stress effects of flumioxazin herbicide on grapevine ( Vitis vinifera L.) grown in vitro.
PubMed:Impact of flumioxazin herbicide on growth and carbohydrate physiology in Vitis vinifera L.
PubMed:[Study on the residual dynamics of flumioxazin in soybean and soil].
PubMed:Photosynthetic responses of Lemna minor exposed to xenobiotics, copper, and their combinations.
PubMed:A plastidic ABC protein involved in intercompartmental communication of light signaling.
PubMed:Metabolism of 7-fluoro-6-(3,4,5,6-tetrahydrophthalimido)-4- (2-propynyl)-2H-1,4-benzoxazin-3(4H)-one (S-53482, flumioxazin) in the rat: II. Identification of reduced metabolites.
PubMed:Metabolism of 7-fluoro-6-(3,4,5,6-tetrahydrophthalimido)-4- (2-propynyl)-2H-1,4-benzoxazin-3(4H)-one (S-53482) in rat. 1. Identification of a sulfonic acid type conjugate.
PubMed:Histological changes in rat embryonic blood cells as a possible mechanism for ventricular septal defects produced by an N-phenylimide herbicide.
 
Notes:
Herbicide used on soybeans, peanuts, orchard fruits and other crops
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