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tetraconazole
1H-1,2,4-triazole, 1-[2-(2,4-dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-

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CAS Number: 112281-77-3Picture of molecule3D/inchi
FDA UNII: 8FGY868T0G
Beilstein Number:6638561
MDL:MFCD01632314
XlogP3-AA:4.40 (est)
Molecular Weight:372.14848280
Formula:C13 H11 Cl2 F4 N3 O
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:herbicides / pesticides
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
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Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 6.00 °C. @ 760.00 mm Hg
Boiling Point: 438.44 °C. @ 760.00 mm Hg (est)
Vapor Pressure:1.350000 mmHg @ 20.00 °C. (est)
Flash Point: 426.00 °F. TCC ( 219.00 °C. ) (est)
logP (o/w): 3.560
Soluble in:
 water, 156 mg/L @ 20 °C (exp)
 water, 4.142 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
Tetraconazole
Sigma-Aldrich
For experimental / research use only.
Tetraconazole PESTANAL®, analytical standard
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
herbicides / pesticides
Recommendation for tetraconazole usage levels up to:
 not for fragrance use.
 
Recommendation for tetraconazole flavor usage levels up to:
 not for flavor use.
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Reasoned opinion on the modification of the existing MRLs for tetraconazole in commodities of plant and animal origin
View page or View pdf

Retrospective analysis of the immunotoxic effects of plant protection products as reported in the Draft Assessment Reports for their peer review at EU level
View page or View pdf

Modification of the existing maximum residue levels for tetraconazole in kaki/Japanese persimmon, linseeds and poppy seeds
View page or View pdf

EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :80277
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
1-[2-(2,4-dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1,2,4-triazole
Chemidplus:0112281773
 
References:
 1-[2-(2,4-dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1,2,4-triazole
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):80277
Pubchem (sid):135039237
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C18490
HMDB (The Human Metabolome Database):Search
ChemSpider:View
Wikipedia:View
Formulations/Preparations:
•emulsifiable concentrate, oil-in-water emulsion, liquid for seed treatment. •tetraconazole technical: active ingredient 97% tetraconazole. •eminent 125sl fungicide: active ingredient 11.6% tetraconazole. •tetraconazole technical: active ingredient 97% tetraconazole. •domark 230 me fungicide: active ingredient 20.5% tetraconazole. •mettle 125me fungicide: active ingredient 11.6% tetraconazole.
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
1-[2-(2,4-dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1,2,4-triazole
1-[2-(2,4-dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1H-1,2,4-triazole
(RS)-2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propyl 1,1,2,2-tetrafluoroethyl ether
1H-1,2,4-triazole, 1-[2-(2,4-dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-
 

Articles:

PubMed:Effect of tetraconazole application on the soil microbial community.
PubMed:Simultaneous stereoselective detection of chiral fungicides in soil by LC-MS/MS with fast sample preparation.
PubMed:Development and application of recombinant antibody-based immunoassays to tetraconazole residue analysis in fruit juices.
PubMed:Dissipation kinetics of tetraconazole in three types of soil and water under laboratory condition.
PubMed:Multiresidue pesticide analysis of botanical dietary supplements using salt-out acetonitrile extraction, solid-phase extraction cleanup column, and gas chromatography-triple quadrupole mass spectrometry.
PubMed:Investigating the potential of metal-organic framework material as an adsorbent for matrix solid-phase dispersion extraction of pesticides during analysis of dehydrated Hyptis pectinata medicinal plant by GC/MS.
PubMed:Effect of preharvest anti-fungal compounds on Aspergillus steynii and A. carbonarius under fluctuating and extreme environmental conditions.
PubMed:[Determination of 11 triazole fungicides in fruits using solid phase extraction and gas chromatography-tandem mass spectrometry].
PubMed:Pesticide residues in Portuguese strawberries grown in 2009-2010 using integrated pest management and organic farming.
PubMed:Inhibitory effects of azole-type fungicides on interleukin-17 gene expression via retinoic acid receptor-related orphan receptors α and γ.
PubMed:Enantioselective determination of triazole fungice tetraconazole by chiral high-performance liquid chromatography and its application to pharmacokinetic study in cucumber, muskmelon, and soils.
PubMed:Simultaneous enantioselective determination of triazole fungicides in soil and water by chiral liquid chromatography/tandem mass spectrometry.
PubMed:Characterization of CbCyp51 from field isolates of Cercospora beticola.
PubMed:Residual fate of the fungicide tetraconazole (4% EW) in mango.
PubMed:Enantiomeric separation of triazole fungicides with 3-μm and 5-μml particle chiral columns by reverse-phase high-performance liquid chromatography.
PubMed:Removal of pesticide mixtures in a stormwater wetland collecting runoff from a vineyard catchment.
PubMed:Coordination polymer adsorbent for matrix solid-phase dispersion extraction of pesticides during analysis of dehydrated Hyptis pectinata medicinal plant by GC/MS.
PubMed:A matrix solid-phase dispersion method for the extraction of seven pesticides from mango and papaya.
PubMed:Development of monoclonal immunoassays for the determination of triazole fungicides in fruit juices.
PubMed:Degradation kinetics and safety evaluation of tetraconazole and difenoconazole residues in grape.
PubMed:Synthesis and antifungal activity of a series of N-substituted [2-(2,4-dichlorophenyl)-3-(1,2,4-triazol-1-yl)]propylamines.
PubMed:Determination of tetraconazole and diniconazole fungicide residues in tomatoes and green beans by capillary gas chromatography.
PubMed:Safe apples for baby-food production: survey of pesticide treatment regimes leaving minimum residues.
PubMed:[Susceptibility of Trichogramma pretiosum Riley (Hymenoptera: Trichogrammatidae) adults to fungicides used to control apple diseases].
PubMed:Bioaccumulation and biotransformation of chiral triazole fungicides in rainbow trout (Oncorhynchus mykiss).
PubMed:In vitro selection of an effective fungicide against Armillaria mellea and control of white root rot of grapevine in the field.
PubMed:Determination of 22 triazole compounds including parent fungicides and metabolites in apples, peaches, flour, and water by liquid chromatography/tandem mass spectrometry.
PubMed:Determination of azolic fungicides in wine by solid-phase extraction and high-performance liquid chromatography-atmospheric pressure chemical ionization-mass spectrometry.
PubMed:Disposable biosensor test for organophosphate and carbamate insecticides in milk.
PubMed:Chiral separation of some triazole pesticides by supercritical fluid chromatography.
PubMed:Application of liquid chromatography with electrospray tandem mass spectrometry to the determination of a new generation of pesticides in processed fruits and vegetables.
PubMed:Characterization of field-isolates and derived DMI-resistant strains of Cercospora beticola.
PubMed:Simultaneous determination of six triazolic pesticide residues in apple and pear pulps by liquid chromatography with ultraviolet diode array detection.
PubMed:High-performance chiral separation of fourteen triazole fungicides by sulfated beta-cyclodextrin-mediated capillary electrophoresis.
PubMed:Synthesis, fungicidal activity, and QSAR of a series of 2-dichlorophenyl-3-triazolylpropyl ethers.
PubMed:Pesticide residues in grapes, wine, and their processing products.
PubMed:Pesticides in fermentative processes of wine.
PubMed:Gas chromatographic determination of azoxystrobin, fluazinam, kresoxim-methyl, mepanipyrim, and tetraconazole in grapes, must, and wine.
PubMed:Differential inhibition of Candida albicans CYP51 with azole antifungal stereoisomers.
 
Notes:
a fungicide.
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