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Category:fungicides
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Melting Point: | 75.90 °C. @ 760.00 mm Hg
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| Boiling Point: | 405.99 °C. @ 760.00 mm Hg (est)
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| Flash Point: | 391.00 °F. TCC ( 199.30 °C. ) (est)
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| logP (o/w): | 4.000 |
| Soluble in: |
| | water, 12.38 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | fungicides |
| Recommendation for cyprodinil usage levels up to: | | | not for fragrance use.
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| Recommendation for cyprodinil flavor usage levels up to: |
| | not for flavor use.
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Safety References:
European Food Safety Authority (EFSA) reference(s):
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Reasoned opinion on the modification of the existing MRLs for cyprodinil in radishes and cucurbits inedible peel
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Reasoned opinion on the review of the existing maximum residue levels (MRLs) for cyprodinil according to Article 12 of Regulation (EC) No 396/2005
View page or View pdf
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Reasoned opinion on the modification of the existing MRL for cyprodinil in celery
View page or View pdf
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Retrospective analysis of the immunotoxic effects of plant protection products as reported in the Draft Assessment Reports for their peer review at EU level
View page or View pdf
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Modification of the existing maximum residue level for cyprodinil in Florence fennel
View page or View pdf
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Modification of the existing maximum residue level for cyprodinil in rhubarbs
View page or View pdf
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Modification of the existing maximum residue levels for cyprodinil in blueberries, cranberries, currants and gooseberries
View page or View pdf
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| EPI System: View |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :86367 |
| National Institute of Allergy and Infectious Diseases:Data |
| WGK Germany:2 |
| 4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine |
| Chemidplus:0121552612 |
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| (6- | cyclopropyl-4-methylpyrimidin-2-yl)phenylamine | | 4- | cyclopropyl-6-methyl-N-phenyl-2-pyrimidinamine | | 4- | cyclopropyl-6-methyl-N-phenyl-pyrimidin-2-amine | | 4- | cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine | | | cyprodonil | | 2- | pyrimidinamine, 4-cyclopropyl-6-methyl-N-phenyl- |
Articles:
| PubMed:Optimization of dispersive liquid-liquid microextraction based on the solidification of floating organic droplets using an orthogonal array design and its application for the determination of fungicide concentrations in environmental water samples. |
| PubMed:Cyprodinil retention on mixtures of soil and solid wastes from wineries. Effects of waste dose and ageing. |
| PubMed:Determination of fungicides in white grape bagasse by pressurized liquid extraction and gas chromatography tandem mass spectrometry. |
| PubMed:Effects of current-use fungicides and their mixtures on the feeding and survival of the key shredder Gammarus fossarum. |
| PubMed:Determination of fungicides in sediments using a dispersive liquid-liquid microextraction procedure based on solidification of floating organic drop. |
| PubMed:In-package nonthermal plasma degradation of pesticides on fresh produce. |
| PubMed:Genetic diversity in Monilinia laxa populations in stone fruit species in Hungary. |
| PubMed:Synthesis of 2-acyloxycyclohexylsulfonamides and evaluation on their fungicidal activity. |
| PubMed:Influence of an intensive agricultural drainage basin on the seasonal distribution of organic pollutants in seawater from a Mediterranean coastal lagoon (Mar Menor, SE Spain). |
| PubMed:Environmental monitoring of pesticide residues from farms at a neighbouring primary and pre-school in the Western Cape in South Africa. |
| PubMed:Processing factor for a selected group of pesticides in a wine-making process: distribution of pesticides during grape processing. |
| PubMed:Effect of phenylpyrrole-resistance on fitness parameters and ochratoxin production in Aspergillus carbonarius. |
| PubMed:Method development and validation for cyprodinil and fludioxonil in blueberries by solid-phase microextraction gas chromatography, and their degradation kinetics. |
| PubMed:Pesticide residues in berries harvested from South-Eastern Poland (2009-2011). |
| PubMed:Effects of single pesticides and binary pesticide mixtures on estrone production in H295R cells. |
| PubMed:Molecular characterization, fitness and mycotoxin production of benzimidazole-resistant isolates of Penicillium expansum. |
| PubMed:Effect of nonpersistent pesticides on estrogen receptor, androgen receptor, and aryl hydrocarbon receptor. |
| PubMed:Simultaneous determination of pyrimethanil, cyprodinil, mepanipyrim and its metabolite in fresh and home-processed fruit and vegetables by a QuEChERS method coupled with UPLC-MS/MS. |
| PubMed:Liquid chromatography time-of-flight mass spectrometry evaluation of fungicides reactivity in free chlorine containing water samples. |
| PubMed:[Determination of fungicide anilinopyrimidine residues in food by series solid phase extraction-high performance liquid chromatography-tandem mass spectrometry]. |
| PubMed:Cyprodinil as an activator of aryl hydrocarbon receptor. |
| PubMed:Gray mold populations in german strawberry fields are resistant to multiple fungicides and dominated by a novel clade closely related to Botrytis cinerea. |
| PubMed:Comparison of the selectivity of different sorbent phases for bar adsorptive microextraction--application to trace level analysis of fungicides in real matrices. |
| PubMed:Fungicide resistance status in French populations of the wheat eyespot fungi Oculimacula acuformis and Oculimacula yallundae. |
| PubMed:Competitive androgen receptor antagonism as a factor determining the predictability of cumulative antiandrogenic effects of widely used pesticides. |
| PubMed:Monitoring pesticide residues in greenhouse tomato by combining acetonitrile-based extraction with dispersive liquid-liquid microextraction followed by gas-chromatography-mass spectrometry. |
| PubMed:A preliminary investigation into the impact of a pesticide combination on human neuronal and glial cell lines in vitro. |
| PubMed:Protocol for an electrospray ionization tandem mass spectral product ion library: development and application for identification of 240 pesticides in foods. |
| PubMed:Impact of fungicides on the diversity and function of non-target ammonia-oxidizing microorganisms residing in a litter soil cover. |
| PubMed:Assessment of spent mushroom substrate as sorbent of fungicides: influence of sorbent and sorbate properties. |
| PubMed:Pesticide residues in Portuguese strawberries grown in 2009-2010 using integrated pest management and organic farming. |
| PubMed:Immunoreagent generation and competitive assay development for cyprodinil analysis. |
| PubMed:Residues behavior of some fungicides applied on two greenhouse tomato varieties different in shape and weight. |
| PubMed:Genotoxicity of pesticide mixtures present in the diet of the French population. |
| PubMed:Biological activity of the succinate dehydrogenase inhibitor fluopyram against Botrytis cinerea and fungal baseline sensitivity. |
| PubMed:Pre-harvest treatments with fungicides and post-harvest dips in sodium bicarbonate to control postharvest decay in stone fruit. |
| PubMed:Determination of farm workers' exposure to pesticides by hair analysis. |
| PubMed:Pesticide removal from waste spray-tank water by organoclay adsorption after field application: an approach for a formulation of cyprodinil containing antifoaming/defoaming agents. |
| PubMed:Simultaneous analysis of pesticides from different chemical classes by using a derivatisation step and gas chromatography-mass spectrometry. |
| PubMed:Influence of the adjuvants in a commercial formulation of the fungicide "Switch" on the adsorption of their active ingredients: cyprodinil and fludioxonil, on soils devoted to vineyard. |
| PubMed:Heterogeneous photocatalytic oxidation of cyprodinil and fludioxonil in leaching water under solar irradiation. |
| PubMed:Structural and functional effects of conventional and low pesticide input crop-protection programs on benthic macroinvertebrate communities in outdoor pond mesocosms. |
| PubMed:Remediation of fungicide residues on fresh produce by use of gaseous ozone. |
| PubMed:Glove accumulation of pesticide residues for strawberry harvester exposure assessment. |
| PubMed:Effect of anilinopyrimidine resistance on aflatoxin production and fitness parameters in Aspergillus parasiticus Speare. |
| PubMed:Solid-phase extraction followed by liquid chromatography quadrupole time-of-flight tandem mass spectrometry for the selective determination of fungicides in wine samples. |
| PubMed:Dissipation and residue of cyprodinil in strawberry and soil. |
| PubMed:Widely used pesticides with previously unknown endocrine activity revealed as in vitro antiandrogens. |
| PubMed:Reducing the impact of pesticides on biological control in Australian vineyards: pesticide mortality and fecundity effects on an indicator species, the predatory mite Euseius victoriensis (Acari: Phytoseiidae). |
| PubMed:Use of farming and agro-industrial wastes as versatile barriers in reducing pesticide leaching through soil columns. |
| PubMed:Sensitivity of Penicillium expansum field isolates to tebuconazole, iprodione, fludioxonil and cyprodinil and characterization of fitness parameters and patulin production. |
| PubMed:Effect of reduced risk pesticides on greenhouse vegetable arthropod biological control agents. |
| PubMed:Analytical method for assessing potential dermal exposure to pesticides of a non-agricultural occupationally exposed population. |
| PubMed:Analysis of cyprodinil in leek and pepper and its decline under field conditions. |
| PubMed:Chemical and biological control of Sclerotinia sclerotiorum in witloof chicory culture. |
| PubMed:Multiple resistance of Botrytis cinerea from kiwifruit to SDHIs, QoIs and fungicides of other chemical groups. |
| PubMed:The effect of fungicides on yeast communities associated with grape berries. |
| PubMed:Retention capacity of an organic bio-mixture against different mixtures of fungicides used in vineyards. |
| PubMed:Solarization and biosolarization enhance fungicide dissipation in the soil. |
| PubMed:Multi-residue analysis of 30 currently used pesticides in fine airborne particulate matter (PM 2.5) by microwave-assisted extraction and liquid chromatography-tandem mass spectrometry. |
| PubMed:Design, synthesis and fungicidal activity of novel strobilurin analogues containing substituted N-phenylpyrimidin-2-amines. |
| PubMed:Effect of reduced risk pesticides for use in greenhouse vegetable production on Bombus impatiens (Hymenoptera: Apidae). |
| PubMed:Antimutagenic and antigenotoxic effects of vegetable matrices on the activity of pesticides. |
| PubMed:Influence of post-harvest application rates of cyprodinil, treatment time and temperature on residue levels and efficacy in controlling green mould on 'Valencia' oranges. |
| PubMed:Baseline sensitivity to proquinazid in Blumeria graminis f. sp. tritici and Erysiphe necator and cross-resistance with other fungicides. |
| PubMed:Analytical method for simultaneous determination of pesticide and veterinary drug residues in milk by CE-MS. |
| PubMed:Effectiveness of control strategies against Botrytis cinerea in vineyard and evaluation of the residual fungicide concentrations. |
| PubMed:Multiresidue analysis of 83 pesticides and 12 dioxin-like polychlorinated biphenyls in wine by gas chromatography-time-of-flight mass spectrometry. |
| PubMed:[Occurrence of plant protection product residues in apples in 2007]. |
| PubMed:Evaluation of the field dissipation of fungicides and insecticides used on fruit bearing trees in northern Italy. |
| PubMed:Sampling atmospheric pesticides with SPME: Laboratory developments and field study. |
| PubMed:Simultaneous determination of seven pesticides in waters using multi-walled carbon nanotube SPE and NACE. |
| PubMed:Stability and fitness of anilinopyrimidine-resistant strains of Botrytis cinerea. |
| PubMed:Characterization of genetic and biochemical mechanisms of fludioxonil and pyrimethanil resistance in field isolates of Penicillium digitatum. |
| PubMed:Multiresidue method for fast determination of pesticides in fruit juices by ultra performance liquid chromatography coupled to tandem mass spectrometry. |
| PubMed:Synergistic interactions between chitinase ChiCW and fungicides against plant fungal pathogens. |
| PubMed:Pesticide residues in grapes from vineyards included in integrated pest management in Slovenia. |
| PubMed:Determination of 23 pesticide residues in leafy vegetables using gas chromatography-ion trap mass spectrometry and analyte protectants. |
| PubMed:Evaluation of anilinopyrimidine and other fungicides for control of grey mould (Botrytis cinerea) in container-grown Calluna vulgaris. |
| PubMed:Potential of 11 pesticides to initiate downstream drift of stream macroinvertebrates. |
| PubMed:Pesticide residues in Italian Ready-Meals and dietary intake estimation. |
| PubMed:Degradation of cyprodinil, fludioxonil, cyfluthrin and pymetrozine on lettuce after different application methods. |
| PubMed:Effect of preharvest fungicides and interacting fungi on Aspergillus carbonarius growth and ochratoxin A synthesis in dehydrating grapes. |
| PubMed:Seasonal distributions of fungicides in soils and sediments of a small river basin partially devoted to vineyards. |
| PubMed:Determination of pesticide residues in foods by acetonitrile extraction and partitioning with magnesium sulfate: collaborative study. |
| PubMed:Effect of chemical treatments on ochratoxigenic fungi and common mycobiota of grapes (Vitis vinifera). |
| PubMed:Molecularly imprinted solid-phase extraction method for the high-performance liquid chromatographic analysis of fungicide pyrimethanil in wine. |
| PubMed:Impact of fungicides on Aspergillus carbonarius growth and ochratoxin A production on synthetic grape-like medium and on grapes. |
| PubMed:Degradation of anilinopyrimidine fungicides photoinduced by iron(III)-polycarboxylate complexes. |
| PubMed:Determination of pesticides in wine using micellar electrokinetic chromatography with UV detection and sample stacking. |
| PubMed:Influence of methanol on the dynamics of the retention and release of cyprodinil by an agricultural soil. |
| PubMed:Azole and fungicide resistance in clinical and environmental Aspergillus fumigatus isolates. |
| PubMed:Effects of clarification and filtration processes on the removal of fungicide residues in red wines (var. Monastrell). |
| PubMed:Adsorption-desorption dynamics of cyprodinil and fludioxonil in vineyard soils. |
| PubMed:Combining solid-phase microextraction and on-line preconcentration-capillary electrophoresis for sensitive analysis of pesticides in foods. |
| PubMed:Fungicide dissipation curves in winemaking processes with and without maceration step. |
| PubMed:Investigation on the chemical structure of nonextractable residues of the fungicide cyprodinil in spring wheat using 13C-C1-phenyl-cyprodinil on 13C-depleted plants-an alternative approach to investigate nonextractable residues. |
| PubMed:Parameters affecting extraction of selected fungicides from vineyard soils. |
| PubMed:Highly sensitive analysis of multiple pesticides in foods combining solid-phase microextraction, capillary electrophoresis-mass spectrometry, and chemometrics. |
| PubMed:Effect of phenolic mediators and humic acid on cyprodinil transformation in presence of birnessite. |
| PubMed:Effect of fungicide residues on the aromatic composition of white wine inoculated with three Saccharomyces cerevisiae strains. |
| PubMed:Characterization of the bound residues of the fungicide cyprodinil formed in plant cell suspension cultures of wheat. |
| PubMed:Dissipation rates of cyprodinil and fludioxonil in lettuce and table grape in the field and under cold storage conditions. |
| PubMed:Determination of fungicide residues in white grapes for winemaking by gas chromatography with mass spectrometric detection and assessment of matrix effects. |
| PubMed:Fungicide sprays can injure the stigmatic surface during receptivity in almond flowers. |
| PubMed:Transformation of the fungicide cyprodinil by a laccase of Trametes villosa in the presence of phenolic mediators and humic acid. |
| PubMed:Assessing the transfer of pesticides to the atmosphere during and after application. Development of a multiresidue method using adsorption on Tenax and thermal desorption-GC/MS. |
| PubMed:Disappearance of azoxystrobin, pyrimethanil, cyprodinil, and fludioxonil on tomatoes in a greenhouse. |
| PubMed:Solid-phase microextraction-gas chromatographic-mass spectrometric method for the determination of the fungicides cyprodinil and fludioxonil in white wines. |
| PubMed:The ABC transporter BcatrB from Botrytis cinerea is a determinant of the activity of the phenylpyrrole fungicide fludioxonil. |
| PubMed:Syringolin reprograms wheat to undergo hypersensitive cell death in a compatible interaction with powdery mildew. |
| PubMed:Pesticide residues in grapes, wine, and their processing products. |
| PubMed:Pesticides in fermentative processes of wine. |
| PubMed:Gas chromatographic determination of cyprodinil, fludioxonil, pyrimethanil, and tebuconazole in grapes, must, and wine. |
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Cyprodinil is a fungicide.
Cyprodinil belongs to the family of Aminopyrimidines and Derivatives. These are organic compounds containing an amino group attached to a pyrimidine ring. Aminopyrimidines play an important role in biological processes, since the pyrimidine ring is present in several vitamins, nucleic acids, and coenzymes [1]. (Reference: [1] Anjani Solankee, Kishor Kapadia, Pankit Solankee, Yogesh Prajapati, Hiral Patel, Sejal Solankee. Synthesis and studies of some novel s-triazine based aminopyrimidines, isoxazoles and 1,5-benzothiazepines. Indian Journal of Chemistry Vol. 46B, October 2007, pp. 1707-1712.).
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3D/inchi