EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

chromium picolinate
chromium tripicolinate

Supplier Sponsors

CAS Number: 14639-25-9Picture of molecule3D/inchi
Other(deleted CASRN):140947-78-0
FDA UNII: S71T8B8Z6P
Nikkaji Web:J790.269G
MDL:MFCD00068715
Molecular Weight:418.30594000
Formula:C18 H12 Cr N3 O6
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:dietary supplements
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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 FDA/DG SANTE Petitions, Reviews, Notices:
GRN 36 Chromium picolinate; Ginkgo biloba leaf extract; and Ginseng extract View - notice PDF
 
Physical Properties:
Appearance:violet red crystalline powder (est)
Assay: 98.00 to 100.00
Food Chemicals Codex Listed: No
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
Soluble in:
 slightly soluble in water at pH 7
 
Organoleptic Properties:
Odor Strength:none
Odor Description:at 100.00 %. odorless
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
American International Chemical, LLC.
CHROMIUM PICOLINATE USP
BOC Sciences
For experimental / research use only.
Chromium(III) Pyridine-2-carboxylate
Glentham Life Sciences
Chromium picolinate
Global Calcium
Chromium Picolinate
Penta International
CHROMIUM PICOLINATE
Qingdao Dacon Trading
Chromium Picolinate
Sigma-Aldrich: Sigma
For experimental / research use only.
Chromium Picolinate ≥98% (HPLC)
sds
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-human LD50 0.008571 mg/kg
American Journal of Psychiatry. Vol. 150, Pg. 1560, 1993.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
dietary supplements
Recommendation for chromium picolinate usage levels up to:
 not for fragrance use.
 
Recommendation for chromium picolinate flavor usage levels up to:
 not for flavor use.
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Scientific Opinion on the safety of chromium picolinate as a source of chromium added for nutritional purposes to foodstuff for particular nutritional uses and to foods intended for the general population
View page or View pdf

Chromium picolinate, zinc picolinate and zinc picolinate dihydrate added for nutritional purposes in food supplements
View page or View pdf

Scientific Opinion on the risks to public health related to the presence of chromium in food and drinking water
View page or View pdf

ClinicalTrials.gov:search
Daily Med:search
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :151932
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
chromium(3+); pyridine-2-carboxylate
Chemidplus:0140947780
 
References:
 chromium(3+); pyridine-2-carboxylate
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):151932
Pubchem (sid):135155475
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
HMDB (The Human Metabolome Database):Search
FDA Listing of Food Additive Status:View
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 chromium 2-pyridinecarboxylate
 chromium tripicolinate
 chromium(3+); pyridine-2-carboxylate
 chromium(III) trispicolinate
 picolinic acid chromium salt
 

Articles:

PubMed:Chromium picolinate reduces insulin resistance in polycystic ovary syndrome: Randomized controlled trial.
PubMed:Effect of chromium picolinate and melatonin either in single or in a combination in high carbohydrate diet-fed male Wistar rats.
PubMed:The Effect of Tianmai Xiaoke Pian on Insulin Resistance through PI3-K/AKT Signal Pathway.
PubMed:Comment on "The Effect of Chromium Picolinate Supplementation on the Pancreas and Macroangiopathy in Type II Diabetes Mellitus Rats".
PubMed:Organoselenium Small Molecules and Chromium(III) Complexes for Intervention in Chronic Low-grade Inflammation and Type 2 Diabetes.
PubMed:Beneficial effects of oral chromium picolinate supplementation on glycemic control in patients with type 2 diabetes: A randomized clinical study.
PubMed:Chromium Supplementation and the Effects on Metabolic Status in Women with Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial.
PubMed:Effects of chromium malate on glycometabolism, glycometabolism-related enzyme levels and lipid metabolism in type 2 diabetic rats: A dose-response and curative effects study.
PubMed:Type 2 diabetic rats on diet supplemented with chromium malate show improved glycometabolism, glycometabolism-related enzyme levels and lipid metabolism.
PubMed:Blood Parameters and Toxicity of Chromium Picolinate Oral Supplementation in Lambs.
PubMed:Evaluation of 90-day Repeated Dose Oral Toxicity, Glycometabolism, Learning and Memory Ability, and Related Enzyme of Chromium Malate Supplementation in Sprague-Dawley Rats.
PubMed:Evaluation of the Reproductive Toxicity, Glycometabolism, Glycometabolism-Related Enzyme Levels and Lipid Metabolism of Chromium Malate Supplementation in Sprague-Dawley Rats.
PubMed:The effect of chromium supplementation on polycystic ovary syndrome in adolescents.
PubMed:Simultaneous analysis of Cr(III), Cr(VI), and chromium picolinate in foods using capillary electrophoresis-inductively coupled plasma mass spectrometry.
PubMed:Physiological, biochemical and histometric responses of Nile tilapia (Oreochromis niloticus L.) by dietary organic chromium (chromium picolinate) supplementation.
PubMed:Controlling diabetes by chromium complexes: The role of the ligands.
PubMed:Effects of dietary supplementation of organic chromium (picolinate) on physical and biochemical characteristics of semen and carcass traits of male turkeys.
PubMed:Chromium Therapy for Insulin Resistance Associated with HIV-Disease.
PubMed:Dietary nano-chromium tripicolinate increases feed intake and decreases plasma cortisol in finisher gilts during summer.
PubMed:The effect of chromium picolinate supplementation on the pancreas and macroangiopathy in type II diabetes mellitus rats.
PubMed:Possible involvement of corticosterone and serotonin in antidepressant and antianxiety effects of chromium picolinate in chronic unpredictable mild stress induced depression and anxiety in rats.
PubMed:Effects of supplemental nanoparticle trivalent chromium on the nutrient utilization, growth performance and serum traits of broilers.
PubMed:Effects of temperature-humidity index and chromium supplementation on antioxidant capacity, heat shock protein 72, and cytokine responses of lactating cows.
PubMed:Chromium-containing traditional Chinese medicine, Tianmai Xiaoke Tablet improves blood glucose through activating insulin-signaling pathway and inhibiting PTP1B and PCK2 in diabetic rats.
PubMed:Metformin versus chromium picolinate in clomiphene citrate-resistant patients with PCOs: A double-blind randomized clinical trial.
PubMed:Systematic review and meta-analysis of the efficacy and safety of chromium supplementation in diabetes.
PubMed:Chromium picolinate inhibits cholesterol-induced stimulation of platelet aggregation in hypercholesterolemic rats.
PubMed:Preventive effects of selenium yeast, chromium picolinate, zinc sulfate and their combination on oxidative stress, inflammation, impaired angiogenesis and atherogenesis in myocardial infarction in rats.
PubMed:Performance, egg quality traits, and serum metabolite concentrations of laying hens affected by dietary supplemental chromium picolinate and vitamin C under a heat-stress condition.
PubMed:Chromium picolinate supplementation for overweight or obese adults.
PubMed:High selenium impairs hepatic insulin sensitivity through opposite regulation of ROS.
PubMed:Effects of dietary chromium picolinate and peppermint essential oil on growth performance and blood biochemical parameters of broiler chicks reared under heat stress conditions.
PubMed:Solexa sequencing of microRNAs on chromium metabolism in broiler chicks.
PubMed:Effects of chromium picolinate on the viability of chick embryo fibroblast.
PubMed:Humoral and cellular immunity in chromium picolinate-supplemented lambs.
PubMed:A double-blind, randomized pilot trial of chromium picolinate for binge eating disorder: results of the Binge Eating and Chromium (BEACh) study.
PubMed:The effects of dietary supplementation with chromium picolinate throughout gestation on productive performance, Cr concentration, serum parameters, and colostrum composition in sows.
PubMed:Nutraceuticals for metabolic syndrome management: from laboratory to benchside.
PubMed:Role of liver fatty acid binding protein in hepatocellular injury: effect of CrPic treatment.
PubMed:Mechanistic insights from the NTP studies of chromium.
PubMed:Comparison of tissue metal concentrations in Zucker lean, Zucker obese, and Zucker diabetic fatty rats and the effects of chromium supplementation on tissue metal concentrations.
PubMed:A novel nutritional supplement containing chromium picolinate, phosphatidylserine, docosahexaenoic acid, and boron activates the antioxidant pathway Nrf2/HO-1 and protects the brain against oxidative stress in high-fat-fed rats.
PubMed:Toxicity evaluation of chromium picolinate nanoparticles in vivo and in vitro in rat.
PubMed:Anti-diabetic activity of chromium picolinate and biotin in rats with type 2 diabetes induced by high-fat diet and streptozotocin.
PubMed:Chromium supplementation in non-obese non-diabetic subjects is associated with a decline in insulin sensitivity.
PubMed:Chromium picolinate attenuates hyperglycemia-induced oxidative stress in streptozotocin-induced diabetic rats.
PubMed:Opinion controversy to chromium picolinate therapy's safety and efficacy: ignoring 'anecdotes' of case reports or recognising individual risks and new guidelines urgency to introduce innovation by predictive diagnostics?
PubMed:Chromium-picolinate therapy in diabetes care: individual outcomes require new guidelines and navigation by predictive diagnostics.
PubMed:[Efficacy of tianmaixiaoke tablets in the treatment of newly diagnosed type 2 diabetes mellitus in China].
PubMed:Bioavailability of chromium(III)-supplements in rats and humans.
PubMed:The effects of chromium picolinate and chromium histidinate administration on NF-κB and Nrf2/HO-1 pathway in the brain of diabetic rats.
PubMed:Effect of chromium dinicocysteinate supplementation on circulating levels of insulin, TNF-α, oxidative stress, and insulin resistance in type 2 diabetic subjects: randomized, double-blind, placebo-controlled study.
PubMed:Anti-atherogenic effect of chromium picolinate in streptozotocin-induced experimental diabetes.
PubMed:Hepatoprotective activity of CrPic against alloxan-induced hepatotoxicity in mice.
PubMed:Chromium picolinate and chromium histidinate protects against renal dysfunction by modulation of NF-κB pathway in high-fat diet fed and Streptozotocin-induced diabetic rats.
PubMed:Chromium picolinate modulates serotonergic properties and carbohydrate metabolism in a rat model of diabetes.
PubMed:Efficacy of dietary chromium (III) supplementation on tissue chromium deposition in finishing pigs.
PubMed:Ameliorating effect of chromium administration on hepatic glucose metabolism in streptozotocin-induced experimental diabetes.
PubMed:Renal distal tubule proliferation and increased aquaporin 2 level but decreased urine osmolality in db/db mouse: treatment with chromium picolinate.
PubMed:Renal and glycemic effects of high-dose chromium picolinate in db/db mice: assessment of DNA damage.
PubMed:Regulation of organic nucleic acids and serum biochemistry parameters by dietary chromium picolinate supplementation in swine model.
PubMed:Chromium-picolinate therapy in diabetes care: molecular and subcellular profiling revealed a necessity for individual outcome prediction, personalised treatment algorithms and new guidelines.
PubMed:Alternative and complementary treatments for metabolic syndrome.
PubMed:Chromium Picolinate for the Prevention of Type 2 Diabetes.
PubMed:Effects of chromium picolinate supplementation on the growth, carcass quality and gene expression of beef during the finishing period.
PubMed:Submandibular gland and caries susceptibility in the obese Zucker rat.
PubMed:Effects of chromium picolinate on vascular reactivity and cardiac ischemia-reperfusion injury in spontaneously hypertensive rats.
PubMed:NTP toxicology and carcinogenesis studies of chromium picolinate monohydrate (CAS No. 27882-76-4) in F344/N rats and B6C3F1 mice (feed studies).
PubMed:Insulin and chromium picolinate induce translocation of CD36 to the plasma membrane through different signaling pathways in 3T3-L1 adipocytes, and with a differential functionality of the CD36.
PubMed:Tissue accumulation and urinary excretion of chromium in rats fed diets containing graded levels of chromium chloride or chromium picolinate.
PubMed:Chromium effects on glucose tolerance and insulin sensitivity in persons at risk for diabetes mellitus.
PubMed:Performance and ruminal protozoa in lambs with chromium supplementation.
PubMed:Effect of chromium picolinate supplementation on growth performance and meat characteristics of swine.
PubMed:Improved cognitive-cerebral function in older adults with chromium supplementation.
PubMed:Chromium dinicocysteinate supplementation can lower blood glucose, CRP, MCP-1, ICAM-1, creatinine, apparently mediated by elevated blood vitamin C and adiponectin and inhibition of NFkappaB, Akt, and Glut-2 in livers of zucker diabetic fatty rats.
PubMed:A pilot study of chromium picolinate for weight loss.
PubMed:Early development of osteoporosis in male smokers with hypoandrogenism due to fascioliasis with or without schistosomiasis added by life style.
PubMed:Cholesterol imbalance in adipocytes: a possible mechanism of adipocytes dysfunction in obesity.
PubMed:Chromium improves protein deposition through regulating the mRNA levels of IGF-1, IGF-1R, and Ub in rat skeletal muscle cells.
PubMed:Effects of chromium picolinate on glycemic control and kidney of the obese Zucker rat.
PubMed:Effect of chromium supplementation on the diabetes induced-oxidative stress in liver and brain of adult rats.
PubMed:Effect of dietary chromium picolinate on growth performance and blood parameters in grass carp fingerling, Ctenopharyngodon idellus.
PubMed:Chromium picolinate does not improve key features of metabolic syndrome in obese nondiabetic adults.
PubMed:Chromium picolinate induced apoptosis of lymphocytes and the signaling mechanisms thereof.
PubMed:Chromium picolinate inhibits resistin secretion in insulin-resistant 3T3-L1 adipocytes via activation of amp-activated protein kinase.
PubMed:Chromium improves glucose uptake and metabolism through upregulating the mRNA levels of IR, GLUT4, GS, and UCP3 in skeletal muscle cells.
PubMed:Effects of chromium picolinate on glucose uptake in insulin-resistant 3T3-L1 adipocytes involve activation of p38 MAPK.
PubMed:Chronic toxicity and carcinogenicity studies of chromium picolinate monohydrate administered in feed to F344/N rats and B6C3F1 mice for 2 years.
PubMed:Determination of mercury in an assortment of dietary supplements using an inexpensive combustion atomic absorption spectrometry technique.
PubMed:Effects of chromium picolinate on oxidative damage in primary piglet hepatocytes.
PubMed:Effects of chromium picolinate on food intake and satiety.
PubMed:Study of oxidative damage in growing-finishing pigs with continuous excess dietary chromium picolinate intake.
PubMed:Chromium supplementation improves glucose tolerance in diabetic Goto-Kakizaki rats.
PubMed:Effect of chromium source on tissue concentration of chromium in pigs.
PubMed:Effects of chromium picolinate on micronucleus frequency and morphology of lymphocytes in calves.
PubMed:A novel membrane-based anti-diabetic action of atorvastatin.
PubMed:Effects of pre- and postnatal exposure to chromium picolinate or picolinic acid on neurological development in CD-1 mice.
PubMed:Chromium nanoparticle exhibits higher absorption efficiency than chromium picolinate and chromium chloride in Caco-2 cell monolayers.
PubMed:Chromium picolinate does not produce chromosome damage.
PubMed:Chromium picolinate for insulin resistance in subjects with HIV disease: a pilot study.
PubMed:Antidiabetogenic effects of chromium mitigate hyperinsulinemia-induced cellular insulin resistance via correction of plasma membrane cholesterol imbalance.
PubMed:Effect of pretreatment with chromium picolinate on haematological parameters during dengue virus infection in mice.
PubMed:Comparison of the potential for developmental toxicity of prenatal exposure to two dietary chromium supplements, chromium picolinate and [Cr3O(O2CCH2CH3)(6(H2O)3]+, in mice.
PubMed:Chromium (D-phenylalanine)3 improves obesity-induced cardiac contractile defect in ob/ob mice.
PubMed:Monitoring blood glucose levels in female mink during the reproductive cycle: 2. Effects of short-term fish oil, chromium picolinate, and acetylsalicylic acid supplementation during late lactation.
PubMed:Monitoring blood glucose levels in female mink during the reproductive cycle: 1. Prevention of hyperglycemia during the nursing period.
PubMed:Chromium in metabolic and cardiovascular disease.
PubMed:Efficacy of chromium(III) supplementation on growth, body composition, serum parameters, and tissue chromium in rats.
PubMed:Effects of supplemental chromium on interferon-gamma (IFN-gamma) mRNA expression in response to Newcastle disease vaccine in broiler chicken.
PubMed:Effect of chronic chromium picolinate in animal models of anxiety and memory.
PubMed:Effect of chromium niacinate and chromium picolinate supplementation on lipid peroxidation, TNF-alpha, IL-6, CRP, glycated hemoglobin, triglycerides, and cholesterol levels in blood of streptozotocin-treated diabetic rats.
PubMed:So many choices, so what's a consumer to do?: A commentary on "Effect of chromium niacinate and chromium picolinate supplementation on lipid peroxidation, TNF-alpha, IL-6, CRP, glycated hemoglobin, triglycerides, and cholesterol levels in blood of streptozotocin-treated diabetic rats".
PubMed:New medications which decrease levothyroxine absorption.
PubMed:Effect of chromium on carbohydrate and lipid metabolism in a rat model of type 2 diabetes mellitus: the fat-fed, streptozotocin-treated rat.
PubMed:Combination of chromium and biotin improves coronary risk factors in hypercholesterolemic type 2 diabetes mellitus: a placebo-controlled, double-blind randomized clinical trial.
PubMed:High glucose and ketosis (acetoacetate) increases, and chromium niacinate decreases, IL-6, IL-8, and MCP-1 secretion and oxidative stress in U937 monocytes.
PubMed:Influence of dietary L-carnitine and chromium picolinate on blood hormones and metabolites of gestating sows fed one meal per day.
PubMed:Chromium picolinate and conjugated linoleic acid do not synergistically influence diet- and exercise-induced changes in body composition and health indexes in overweight women.
PubMed:Chromium picolinate and biotin combination improves glucose metabolism in treated, uncontrolled overweight to obese patients with type 2 diabetes.
PubMed:Chromium picolinate and biotin combination reduces atherogenic index of plasma in patients with type 2 diabetes mellitus: a placebo-controlled, double-blinded, randomized clinical trial.
PubMed:Evaluation of the potential genotoxicity of chromium picolinate in mammalian cells in vivo and in vitro.
PubMed:Chromium treatment has no effect in patients with type 2 diabetes in a Western population: a randomized, double-blind, placebo-controlled trial.
PubMed:Chromium picolinate supplementation in women: effects on body weight, composition, and iron status.
PubMed:Synergistic effects of conjugated linoleic acid and chromium picolinate improve vascular function and renal pathophysiology in the insulin-resistant JCR:LA-cp rat.
PubMed:[Repercussions of chromium picolinate in the protein metabolism based on the age].
PubMed:Chromium picolinate supplementation attenuates body weight gain and increases insulin sensitivity in subjects with type 2 diabetes: response to Martin et al.
PubMed:Availability of weight-loss supplements: Results of an audit of retail outlets in a southeastern city.
PubMed:Clinical studies on chromium picolinate supplementation in diabetes mellitus--a review.
PubMed:The effect of chromium picolinate and biotin supplementation on glycemic control in poorly controlled patients with type 2 diabetes mellitus: a placebo-controlled, double-blinded, randomized trial.
PubMed:Chromium picolinate intake and risk of type 2 diabetes: an evidence-based review by the United States Food and Drug Administration.
PubMed:Chromium-picolinate induced ocular changes: Protective role of ascorbic acid.
PubMed:Nutritional supplement chromium picolinate generates chromosomal aberrations and impedes progeny development in Drosophila melanogaster.
PubMed:Molecular analysis of hprt mutations induced by chromium picolinate in CHO AA8 cells.
PubMed:Chromium picolinate supplementation attenuates body weight gain and increases insulin sensitivity in subjects with type 2 diabetes.
PubMed:Chromium picolinate positively influences the glucose transporter system via affecting cholesterol homeostasis in adipocytes cultured under hyperglycemic diabetic conditions.
PubMed:Toward prevention of Alzheimers disease--potential nutraceutical strategies for suppressing the production of amyloid beta peptides.
PubMed:Exposure of pregnant mice to chromium picolinate results in skeletal defects in their offspring.
PubMed:Effect of chromium on the insulin resistance in patients with type II diabetes mellitus.
PubMed:Chromium picolinate improves insulin sensitivity in obese subjects with polycystic ovary syndrome.
PubMed:Hypoglycemic potency of novel trivalent chromium in hyperglycemic insulin-deficient rats.
PubMed:Chromium treatment has no effect in patients with poorly controlled, insulin-treated type 2 diabetes in an obese Western population: a randomized, double-blind, placebo-controlled trial.
PubMed:Acute tubular necrosis associated with chromium picolinate-containing dietary supplement.
PubMed:Effect of chromium picolinate on modified forced swimming test in diabetic rats: involvement of serotonergic pathways and potassium channels.
PubMed:Chromium picolinate enhances skeletal muscle cellular insulin signaling in vivo in obese, insulin-resistant JCR:LA-cp rats.
PubMed:Effect of chromium supplementation on insulin resistance and ovarian and menstrual cyclicity in women with polycystic ovary syndrome.
PubMed:PKC-mediated modulation of L-type calcium channels may contribute to fat-induced insulin resistance.
PubMed:Chromium picolinate, rather than biotin, alleviates performance and metabolic parameters in heat-stressed quail.
PubMed:Chromium picolinate does not produce chromosome damage in CHO cells.
PubMed:A double-blind, placebo-controlled, exploratory trial of chromium picolinate in atypical depression: effect on carbohydrate craving.
PubMed:Effects of dengue virus infection on peripheral blood cells of mice exposed to hexavalent chromium with drinking water.
PubMed:Effects of chronic chromium picolinate treatment in uninephrectomized rat.
PubMed:Use of chromium picolinate and biotin in the management of type 2 diabetes: an economic analysis.
PubMed:Effects of dietary combination of chromium and biotin on growth performance, carcass characteristics, and oxidative stress markers in heat-distressed Japanese quail.
PubMed:Mutagenicity of chromium picolinate and its components in Salmonella typhimurium and L5178Y mouse lymphoma cells.
PubMed:Supplementation with chromium picolinate recovers renal Cr concentration and improves carbohydrate metabolism and renal function in type 2 diabetic mice.
PubMed:Chromium supplementation shortens QTc interval duration in patients with type 2 diabetes mellitus.
PubMed:Herbs and nutrients in the treatment of depression, anxiety, insomnia, migraine, and obesity.
PubMed:Nonpharmacologic treatments for depression in patients with coronary heart disease.
PubMed:Lack of mutagenicity of chromium picolinate in the hypoxanthine phosphoribosyltransferase gene mutation assay in Chinese hamster ovary cells.
PubMed:Chromium picolinate may favorably influence the vascular risk associated with smoking by combating cortisol-induced insulin resistance.
PubMed:A newly synthetic chromium complex--chromium(phenylalanine)3 improves insulin responsiveness and reduces whole body glucose tolerance.
PubMed:Absence of toxic effects in F344/N rats and B6C3F1 mice following subchronic administration of chromium picolinate monohydrate.
PubMed:Effects of dietary combination of chromium and biotin on egg production, serum metabolites, and egg yolk mineral and cholesterol concentrations in heat-distressed laying quails.
PubMed:Nutraceutical resources for diabetes prevention--an update.
PubMed:Effect of different doses of chromium picolinate on protein metabolism in infant rats.
PubMed:Insulin sensitising action of chromium picolinate in various experimental models of diabetes mellitus.
PubMed:A regional evaluation of chromium tripicolinate supplementation of diets fed to reproducing sows.
PubMed:Effects of supplemental copper and chromium on the serum and egg traits of laying hens.
PubMed:Resistive training and chromium picolinate: effects on inositols and liver and kidney functions in older adults.
PubMed:A validated method for analysis of chromium picolinate in nutraceuticals by reversed phase high performance liquid chromatography.
PubMed:Influence of Carnichrome on the energy balance of gestating sows.
PubMed:Effect of chromium supplementation on blood glucose and lipid levels in type 2 diabetes mellitus elderly patients.
PubMed:Characterizing adverse events reported to the California Poison Control System on herbal remedies and dietary supplements: a pilot study.
PubMed:A scientific review: the role of chromium in insulin resistance.
PubMed:Chromium picolinate supplementation improves insulin sensitivity in Goto-Kakizaki diabetic rats.
PubMed:Determining the safety of chromium tripicolinate for addition to foods as a nutrient supplement.
PubMed:Recent advances in the nutritional biochemistry of trivalent chromium.
PubMed:Dietary supplements for body-weight reduction: a systematic review.
PubMed:[Chromium and insulin resistance].
PubMed:Dietary L-carnitine increases plasma leptin concentrations of gestating sows fed one meal per day.
PubMed:[Dietary supplements and functional food for weight reduction -- expectations and reality].
PubMed:Effect of chromium picolinate on histopathological alterations in STZ and neonatal STZ diabetic rats.
PubMed:Effects of treatment with chromium picolinate on peripheral amino acid availability and brain monoamine function in the rat.
PubMed:In vivo antioxidant properties of vitamin E and chromium in cold-stressed Japanese quails.
PubMed:Chromium picolinate and type 2 diabetes.
PubMed:Antioxidant properties of chromium and zinc: in vivo effects on digestibility, lipid peroxidation, antioxidant vitamins, and some minerals under a low ambient temperature.
PubMed:Chromium picolinate for reducing body weight: meta-analysis of randomized trials.
PubMed:The potential value and toxicity of chromium picolinate as a nutritional supplement, weight loss agent and muscle development agent.
PubMed:Nutritional supplement chromium picolinate causes sterility and lethal mutations in Drosophila melanogaster.
PubMed:Tissue and subcellular distribution of chromium picolinate with time after entering the bloodstream.
PubMed:Effectiveness of chromium in atypical depression: a placebo-controlled trial.
PubMed:Role of chromium supplementation in Indians with type 2 diabetes mellitus.
PubMed:Optimal dietary concentration of chromium for alleviating the effect of heat stress on growth, carcass qualities, and some serum metabolites of broiler chickens.
PubMed:Effects of dietary chromium picolinate and ascorbic acid supplementation on egg production, egg quality and some serum metabolites of laying hens reared under a low ambient temperature (6 degrees C).
PubMed:Assessment of chromium tripicolinate supplementation and dietary protein level on growth, carcass, and blood criteria in growing pigs.
PubMed:Cytotoxicity and oxidative mechanisms of different forms of chromium.
PubMed:Ultrastructural damage in chromium picolinate-treated cells: a TEM study. Transmission electron microscopy.
PubMed:Effects of resistive training and chromium picolinate on body composition and skeletal muscle size in older women.
PubMed:The safety and efficacy of high-dose chromium.
PubMed:Effects of dietary chromium and ascorbic acid supplementation on digestion of nutrients, serum antioxidant status, and mineral concentrations in laying hens reared at a low ambient temperature.
PubMed:Chromium supplementation can alleviate negative effects of heat stress on egg production, egg quality and some serum metabolites of laying Japanese quail.
PubMed:Oral chromium picolinate improves carbohydrate and lipid metabolism and enhances skeletal muscle Glut-4 translocation in obese, hyperinsulinemic (JCR-LA corpulent) rats.
PubMed:Effects of chromium picolinate supplementation on insulin sensitivity, serum lipids, and body weight in dexamethasone-treated rats.
PubMed:Assessment of chromium tripicolinate supplementation and dietary energy level and source on growth, carcass, and blood criteria in growing pigs.
PubMed:Effect of chromium tripicolinate supplementation on porcine immune response during the periparturient and neonatal period.
PubMed:Effect of chromium tripicolinate supplementation on porcine immune response during the postweaning period.
PubMed:Effects of dietary chromium and zinc on egg production, egg quality, and some blood metabolites of laying hens reared under low ambient temperature.
PubMed:Dietary chromium tripicolinate supplementation reduces glucose concentrations and improves glucose tolerance in normal-weight cats.
PubMed:In vivo distribution of chromium from chromium picolinate in rats and implications for the safety of the dietary supplement.
PubMed:Chromium treatment decreases the sensitivity of 5-HT2A receptors.
PubMed:Dietary supplement survey of pharmacists: personal and professional practices.
PubMed:The effect of chromium picolinate on muscular strength and body composition in women athletes.
PubMed:Effects of dietary chromium picolinate supplementation on performance and plasma concentrations of insulin and corticosterone in laying hens under low ambient temperature.
PubMed:Chromium (VI)-induced oxidative stress, apoptotic cell death and modulation of p53 tumor suppressor gene.
PubMed:Effect of chromium picolinate and chromium propionate on glucose and insulin kinetics of growing barrows and on growth and carcass traits of growing-finishing barrows.
PubMed:Effect of chromium supplementation and exercise on body composition, resting metabolic rate and selected biochemical parameters in moderately obese women following an exercise program.
PubMed:Influence of supplemental chromium on concentrations of liver triglyceride, blood metabolites and rumen VFA profile in steers fed a moderately high fat diet.
PubMed:Oral chromium picolinate and control of glycemia in insulin-treated diabetic dogs.
PubMed:Oral medications for treating diabetes mellitus in dogs and cats.
PubMed:Chromium-induced glucose uptake, superoxide anion production, and phagocytosis in cultured pulmonary alveolar macrophages of weanling pigs.
PubMed:Toward practical prevention of type 2 diabetes.
PubMed:Effects of chromium picolinate supplementation on insulin sensitivity, serum lipids, and body composition in healthy, nonobese, older men and women.
PubMed:The binding of trivalent chromium to low-molecular-weight chromium-binding substance (LMWCr) and the transfer of chromium from transferrin and chromium picolinate to LMWCr.
PubMed:The biochemistry of chromium.
PubMed:Systemic contact dermatitis caused by oral chromium picolinate.
PubMed:Effects of carbohydrate and chromium ingestion during intermittent high-intensity exercise to fatigue.
PubMed:The role of chromium in nutrition and therapeutics and as a potential toxin.
PubMed:Influence of chromium tripicolinate on growth and glucose metabolism in yearling horses.
PubMed:Acute generalized exanthematous pustulosis induced by chromium picolinate.
PubMed:Performance, serum characteristics, carcase traits and lipid metabolism of broilers as affected by supplement of chromium picolinate.
PubMed:In vitro metabolism and permeation studies in rat jejunum: organic chromium compared to inorganic chromium.
PubMed:High-dose biotin, an inducer of glucokinase expression, may synergize with chromium picolinate to enable a definitive nutritional therapy for type II diabetes.
PubMed:Four-week supplementation with a natural dietary compound produces favorable changes in body composition.
PubMed:Dietary protein and chromium tripicolinate in Suffolk wether lambs: effects on production characteristics, metabolic and hormonal responses, and immune status.
PubMed:Efficacy of chromium picolinate on performance and tissue accretion in pigs with different lean gain potential.
PubMed:Effect of resistance training with or without chromium picolinate supplementation on glucose metabolism in older men and women.
PubMed:Reversal of corticosteroid-induced diabetes mellitus with supplemental chromium.
PubMed:Chromium potentiation of antidepressant pharmacotherapy for dysthymic disorder in 5 patients.
PubMed:Complementary measures for promoting insulin sensitivity in skeletal muscle.
PubMed:Effects of resistance training and chromium picolinate on body composition and skeletal muscle in older men.
PubMed:Chromium picolinate effects on body composition and muscular performance in wrestlers.
PubMed:Performance and metabolic responses of young dairy calves fed diets supplemented with chromium tripicolinate.
PubMed:Effect of supplementation with chromium picolinate on antibody titers to 5-hydroxymethyl uracil.
PubMed:Suspected chromium picolinate-induced rhabdomyolysis.
PubMed:Chromium picolinate toxicity.
PubMed:Chromium picolinate modulates rat vascular smooth muscle cell intracellular calcium metabolism.
PubMed:Chromium picolinate supplementation for diabetes mellitus.
PubMed:The effectiveness of long-term supplementation of carbohydrate, chromium, fibre and caffeine on weight maintenance.
PubMed:Comparative induction of oxidative stress in cultured J774A.1 macrophage cells by chromium picolinate and chromium nicotinate.
PubMed:Drug therapy for obesity in the elderly.
PubMed:Elevated intakes of supplemental chromium improve glucose and insulin variables in individuals with type 2 diabetes.
PubMed:Efficacy of chromium picolinate and chromium chloride as potential carcass modifiers in swine.
PubMed:Chromium picolinate supplementation and resistive training by older men: effects on iron-status and hematologic indexes.
PubMed:Nutritional factors influencing the glucose/insulin system: chromium.
PubMed:Exploiting complementary therapeutic strategies for the treatment of type II diabetes and prevention of its complications.
PubMed:Chromium and exercise training: effect on obese women.
PubMed:Nutrition Supplements: Science vs Hype.
PubMed:Effect of growth hormone or chromium picolinate on swine metabolism and inflammatory cytokine production after endotoxin challenge exposure.
PubMed:Lack of toxicity of chromium chloride and chromium picolinate in rats.
PubMed:Effects of different chromium compounds on blood pressure and lipid peroxidation in spontaneously hypertensive rats.
PubMed:Supplemental chromium picolinate influences nitrogen balance, dry matter digestibility, and carcass traits in growing-finishing pigs.
PubMed:Interactive effects of dietary chromium tripicolinate and crude protein level in growing-finishing pigs provided inadequate and adequate pen space.
PubMed:Chronic renal failure after ingestion of over-the-counter chromium picolinate.
PubMed:[Effect of chromium yeast and chromium picolinate on body composition of obese, non-diabetic patients during and after a formula diet].
PubMed:Urinary chromium concentrations in humans following ingestion of safe doses of hexavalent and trivalent chromium: implications for biomonitoring.
PubMed:Chromium supplementation and resistance training: effects on body composition, strength, and trace element status of men.
PubMed:Chromium picolinate.
PubMed:Effects of chromium picolinate on body composition.
PubMed:A prediction of chromium(III) accumulation in humans from chromium dietary supplements.
PubMed:Chromium(III) picolinate produces chromosome damage in Chinese hamster ovary cells.
PubMed:[The effect of chromium picolinate on the liver levels of trace elements].
PubMed:Effects of dietary chromium picolinate supplementation on growth, carcass characteristics, and accretion rates of carcass tissues in growing-finishing swine.
PubMed:Influence of chromium tripicolinate on glucose metabolism and nutrient partitioning in growing lambs.
PubMed:Anabolic effects of insulin on bone suggest a role for chromium picolinate in preservation of bone density.
PubMed:Effect of chromium picolinate on growth, body composition, and tissue accretion in pigs.
PubMed:Effect of chromium tripicolinate on growth, glucose tolerance, insulin sensitivity, plasma metabolites, and growth hormone in pigs.
PubMed:Dietary chromium picolinate additions improve gain:feed and carcass characteristics in growing-finishing pigs and increase litter size in reproducing sows.
PubMed:Effect of recombinant growth hormone and chromium picolinate on cytokine production and growth performance in swine.
PubMed:Beneficial effect of chromium supplementation on serum triglyceride levels in NIDDM.
PubMed:Longevity effect of chromium picolinate--'rejuvenation' of hypothalamic function?
PubMed:Enhancing central and peripheral insulin activity as a strategy for the treatment of endogenous depression--an adjuvant role for chromium picolinate?
PubMed:Urinary excretion of chromium by humans following ingestion of chromium picolinate. Implications for biomonitoring.
PubMed:Influence of chromium picolinate on glucose usage and metabolic criteria in growing Holstein calves.
PubMed:Effects of chromium picolinate supplementation on body composition, strength, and urinary chromium loss in football players.
PubMed:Promotion of hepatic lipid oxidation and gluconeogenesis as a strategy for appetite control.
PubMed:Over-the-counter chromium picolinate.
PubMed:Homologous physiological effects of phenformin and chromium picolinate.
PubMed:Insulin resistance in Mexican Americans--a precursor to obesity and diabetes?
PubMed:Dietary chromium supplementation with or without somatotropin treatment alters serum hormones and metabolites in growing pigs without affecting growth performance.
PubMed:Chromium picolinate is an efficacious and safe supplement.
PubMed:Effect of chromium picolinate on growth and serum and carcass traits of growing-finishing pigs.
PubMed:Composition and biological activity of chromium-pyridine carboxylate complexes.
PubMed:Effects of chromium picolinate on beginning weight training students.
PubMed:Chromium picolinate increases membrane fluidity and rate of insulin internalization.
PubMed:The effect of chromium picolinate on serum cholesterol and apolipoprotein fractions in human subjects.
 
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