PubMed:Defining the Critical Material Attributes of Lactose Monohydrate in Carrier Based Dry Powder Inhaler Formulations Using Artificial Neural Networks. |
PubMed:The stability of sugar solutions: A novel study of the epimerisation kinetics of lactose in water. |
PubMed:Efficacy of orally administered maropitant citrate in preventing vomiting associated with hydromorphone administration in dogs. |
PubMed:Chemometrics applied to quantitative analysis of ternary mixtures by terahertz spectroscopy. |
PubMed:Dry powders for oral inhalation free of lactose carrier particles. |
PubMed:Impact of oral meloxicam administered alone or in combination with gabapentin on experimentally induced lameness in beef calves. |
PubMed:Controlled-release cellulose esters matrices for water-soluble diclofenac sodium: compression and dissolution studies. |
PubMed:Functionality of chitin as a direct compression excipient: an acetaminophen comparative study. |
PubMed:Preparation, characterization and pulmonary pharmacokinetics of xyloglucan microspheres as dry powder inhalation. |
PubMed:Taste-masked and affordable donepezil hydrochloride orally disintegrating tablet as promising solution for non-compliance in Alzheimer's disease patients. |
PubMed:"Rolling" phenomenon in twin screw granulation with controlled-release excipients. |
PubMed:Effects and detection of raw material variability on the performance of near-infrared calibration models for pharmaceutical products. |
PubMed:Comparative evaluation of single and bilayered lamotrigine floating tablets. |
PubMed:Hot-melt granulation in a twin screw extruder: effects of processing on formulations with caffeine and Ibuprofen. |
PubMed:Influence of filler selection on twin screw foam granulation. |
PubMed:The tableting properties of melibiose monohydrate. |
PubMed:Spectroscopy of polycrystalline materials using thinned-substrate planar Goubau line at cryogenic temperatures. |
PubMed:Thermal behaviour of procaine and benzocaine Part II: compatibility study with some pharmaceutical excipients used in solid dosage forms. |
PubMed:[Simultaneous quantitative determination of multicomponents in tablets based on terahertz time-domain spectroscopy]. |
PubMed:Direct compression of cellulose and lignin isolated by a new catalytic treatment. |
PubMed:Ultrasonic approach for viscoelastic and microstructure characterization of granular pharmaceutical tablets. |
PubMed:Evaluation of some compression aids in tableting of roller compacted swellable core drug layer. |
PubMed:Design expert supported mathematical optimization and predictability study of buccoadhesive pharmaceutical wafers of Loratadine. |
PubMed:Controlled release of cyclosporine A self-nanoemulsifying systems from osmotic pump tablets: near zero-order release and pharmacokinetics in dogs. |
PubMed:Thermodynamic study of binary system Propafenone Hydrocloride with Metoprolol Tartrate: solid-liquid equilibrium and compatibility with α-lactose monohydrate and corn starch. |
PubMed:The CULTEX RFS: a comprehensive technical approach for the in vitro exposure of airway epithelial cells to the particulate matter at the air-liquid interface. |
PubMed:Production and characterization of pellets using Avicel CL611 as spheronization aid. |
PubMed:Zinc supplementation in pre-diabetes: study protocol for a randomized controlled trial. |
PubMed:Monitoring blending of pharmaceutical powders with multipoint NIR spectroscopy. |
PubMed:Effect of experimental design on the prediction performance of calibration models based on near-infrared spectroscopy for pharmaceutical applications. |
PubMed:Dissolution process analysis using model-free Noyes-Whitney integral equation. |
PubMed:Time-resolved near-infrared spectroscopic study of the dissolution of crystalline lactose. |
PubMed:[A comparative analysis of the influence of different types of Carbopol on the release rate of lithium-carbonate from matrix tablets]. |
PubMed:Chamomile (Matricaria recutita) may provide antidepressant activity in anxious, depressed humans: an exploratory study. |
PubMed:Continuous twin screw granulation: influence of process variables on granule and tablet quality. |
PubMed:Development of a fluid bed granulation design space using critical quality attribute weighted tolerance intervals. |
PubMed:The effect of engineered mannitol-lactose mixture on dry powder inhaler performance. |
PubMed:Influence of primary crystallisation conditions on the mechanical and interfacial properties of micronised budesonide for dry powder inhalation. |
PubMed:Influence of peak inspiratory flow rates and pressure drops on inhalation performance of dry powder inhalers. |
PubMed:An experimental evaluation of an effective medium based compaction equation. |
PubMed:Hiding a realistic object using a broadband terahertz invisibility cloak. |
PubMed:Characterization of critical physical and mechanical properties of freeze-dried grape powder for development of a clinical patient delivery system. |
PubMed:Synthesis of galacto-oligosaccharides by β-galactosidase from Aspergillus oryzae using partially dissolved and supersaturated solution of lactose. |
PubMed:To evaluate the effect of various magnesium stearate polymorphs using powder rheology and thermal analysis. |
PubMed:Stress relaxation study of fillers for directly compressed tablets. |
PubMed:Effect of physical states of binders on high-shear wet granulation and granule properties: a mechanistic approach toward understanding high-shear wet granulation process, part 3: effect of binder rheological properties. |
PubMed:Characterization of oral disintegrating film containing donepezil for Alzheimer disease. |
PubMed:Physico-chemical aspects of lactose for inhalation. |
PubMed:Hybridization induced transparency in composites of metamaterials and atomic media. |
PubMed:Foam granulation: new developments in pharmaceutical solid oral dosage forms using twin screw extrusion machinery. |
PubMed:Influence of the lactose grade within dry powder formulations of fluticasone propionate and terbutaline sulphate. |
PubMed:Poloxamer thermogel systems as medium for crystallization. |
PubMed:The measurement of the β/α anomer composition within amorphous lactose prepared by spray and freeze drying using a simple (1)H-NMR method. |
PubMed:Investigating the effect of solubility and density gradients on local hydrodynamics and drug dissolution in the USP 4 dissolution apparatus. |
PubMed:Acoustic assessment of mean grain size in pharmaceutical compacts. |
PubMed:Compatibility study between ketoprofen and pharmaceutical excipients used in solid dosage forms. |
PubMed:The 'stage-by-stage' deposition of drugs from commercial single-active and combination dry powder inhaler formulations. |
PubMed:Characterization of the surface properties of a model pharmaceutical fine powder modified with a pharmaceutical lubricant to improve flow via a mechanical dry coating approach. |
PubMed:Study of radial die-wall pressure changes during pharmaceutical powder compaction. |
PubMed:Near-infrared chemical imaging slope as a new method to study tablet compaction and tablet relaxation. |
PubMed:Antisolvent crystallization of pharmaceutical excipients from aqueous solutions and the use of preferred orientation in phase identification by powder X-ray diffraction. |
PubMed:Ultrasound transmission measurements for tensile strength evaluation of tablets. |
PubMed:Complex dielectric properties of microcrystalline cellulose, anhydrous lactose, and α-lactose monohydrate powders using a microwave-based open-reflection resonator sensor. |
PubMed:Theoretical and experimental investigations into the delamination tendencies of bilayer tablets. |
PubMed:The impact of material attributes and process parameters on the micronisation of lactose monohydrate. |
PubMed:Improved aerosolization performance of salbutamol sulfate formulated with lactose crystallized from binary mixtures of ethanol-acetone. |
PubMed:The production of 'aerodynamically equivalent' drug and excipient inhalable powders using a novel fractionation technique. |
PubMed:Oral bioavailability of silymarin phytocomplex formulated as self-emulsifying pellets. |
PubMed:The influence of thermal history on the physical behavior of poly(ethylene glycol) (PEG). |
PubMed:Monitoring fluidized bed drying of pharmaceutical granules. |
PubMed:Photoacoustic spectroscopy using coherent synchrotron radiation: application to α-lactose monohydrate. |
PubMed:In-line ultrasound measurement system for detecting tablet integrity. |
PubMed:Elucidation of the internal physical and chemical microstructure of pharmaceutical granules using X-ray micro-computed tomography, Raman microscopy and infrared spectroscopy. |
PubMed:Low powder mass filling of dry powder inhalation formulations. |
PubMed:Inhalation performance of physically mixed dry powders evaluated with a simple simulator for human inspiratory flow patterns. |
PubMed:The in-situ solid-state NMR spectroscopy investigation of alcoholic lactose suspensions. |
PubMed:Amorphization of sugar hydrates upon milling. |
PubMed:Determination of low levels of amorphous content in inhalation grade lactose by moisture sorption isotherms. |
PubMed:Rapid formulation screening with a Multipart Microscale Fluid bed Powder processor. |
PubMed:Application of crustacean chitin as a co-diluent in direct compression of tablets. |
PubMed:Dry powder aerosols generated by standardized entrainment tubes from drug blends with lactose monohydrate: 2. Ipratropium bromide monohydrate and fluticasone propionate. |
PubMed:Melt granulation of pharmaceutical powders: a comparison of high-shear mixer and fluidised bed processes. |
PubMed:Dry powder aerosols generated by standardized entrainment tubes from drug blends with lactose monohydrate: 1. Albuterol sulfate and disodium cromoglycate. |
PubMed:The effect of particle size on the dehydration/rehydration behaviour of lactose. |
PubMed:[Qualitative and quantitative analyses of some saccharides by THz-TDS]. |
PubMed:Evaluation of a rotary tablet press simulator as a tool for the characterization of compaction properties of pharmaceutical products. |
PubMed:Colorful drying. |
PubMed:Influence of fines on the surface energy heterogeneity of lactose for pulmonary drug delivery. |
PubMed:Influence of amorphous content on compaction behaviour of anhydrous alpha-lactose. |
PubMed:Dual-frequency imaging using an electrically tunable terahertz quantum cascade laser. |
PubMed:Influence of excipients in comilling on mitigating milling-induced amorphization or structural disorder of crystalline pharmaceutical actives. |
PubMed:Quantitative X-ray diffraction determination of alpha-lactose monohydrate and beta-lactose in chocolate. |
PubMed:Wet granulation in a twin-screw extruder: implications of screw design. |
PubMed:Production of lactosucrose from sucrose and lactose by a levansucrase from Zymomonas mobilis. |
PubMed:Mechanical properties of excipients do not affect polymer matrix formation. |
PubMed:Effect of chilling on the motility and acrosomal integrity of rat sperm in the presence of various extenders. |
PubMed:Improving powder flow properties of a cohesive lactose monohydrate powder by intensive mechanical dry coating. |
PubMed:Granule size distribution of tablets. |
PubMed:A structural investigation into the compaction behavior of pharmaceutical composites using powder X-ray diffraction and total scattering analysis. |
PubMed:Multivariate analysis of relationships between material properties, process parameters and tablet tensile strength for alpha-lactose monohydrates. |
PubMed:A combined modelling and experimental study of the surface energetics of alpha-lactose monohydrate. |
PubMed:Understanding the effect of lactose particle size on the properties of DPI formulations using experimental design. |
PubMed:Distribution of ethenzamide and other ingredients on granule surfaces studied by Raman microspectroscopy and mapping. |
PubMed:Non-destructive determination of anisotropic mechanical properties of pharmaceutical solid dosage forms. |
PubMed:Compatibility studies of promethazine hydrochloride with tablet excipients by means of thermal and non-thermal methods. |
PubMed:Effective modification of particle surface properties using ultrasonic water mist. |
PubMed:The rheological properties of modified microcrystalline cellulose containing high levels of model drugs. |
PubMed:Evaluation of the composition of the binder bridges in matrix granules prepared with a small-scale high-shear granulator. |
PubMed:Scanning white-light interferometry as a novel technique to quantify the surface roughness of micron-sized particles for inhalation. |
PubMed:Simulation of roller compaction with subsequent tableting and characterization of lactose and microcrystalline cellulose. |
PubMed:Comparison of two twin-screw extruders for continuous granulation. |
PubMed:A near-infrared spectroscopic investigation of relative density and crushing strength in four-component compacts. |
PubMed:Influence of ageing, grinding and preheating on the thermal behaviour of alpha-lactose monohydrate. |
PubMed:The surface characterisation and comparison of two potential sub-micron, sugar bulking excipients for use in low-dose, suspension formulations in metered dose inhalers. |
PubMed:Measuring the distribution of density and tabletting force in pharmaceutical tablets by chemical imaging. |
PubMed:Stability indicating validated HPLC method for quantification of levothyroxine with eight degradation peaks in the presence of excipients. |
PubMed:Moisture sorption, compressibility and caking of lactose polymorphs. |
PubMed:Roller compaction, granulation and capsule product dissolution of drug formulations containing a lactose or mannitol filler, starch, and talc. |
PubMed:Cellactose a co-processed excipient: a comparison study. |
PubMed:Differences in characteristics of pellets prepared by different pelletization methods. |
PubMed:A novel method for estimating solid fraction of roller-compacted ribbons. |
PubMed:Influence of loading volume of mefenamic acid on granules and tablet characteristics using a compaction simulator. |
PubMed:A study of the properties of tablets from coprocessed dry binders composed of alpha-lactose monohydrate and different types of cellulose. |
PubMed:Determination of figures of merit for near-infrared and Raman spectrometry by net analyte signal analysis for a 4-component solid dosage system. |
PubMed:Influence of loading volume of mefenamic acid on granules and tablet characteristics using a compaction simulator. |
PubMed:Studies on the influence of uniformity of particle size of powder, tapping and sample replacement for diffusion reflectance quantitative NIR spectrometric analysis. |
PubMed:Characterization of pharmaceutical powder blends by NIR chemical imaging. |
PubMed:The influence of drug morphology on aerosolisation efficiency of dry powder inhaler formulations. |
PubMed:The effect of relative humidity on electrostatic charge decay of drugs and excipient used in dry powder inhaler formulation. |
PubMed:Compaction of lactose drug mixtures: quantification of the extent of incompatibility by FT-Raman spectroscopy. |
PubMed:An X-ray diffraction analysis of crystallised whey and whey-permeate powders. |
PubMed:Unified compaction curve model for tensile strength of tablets made by roller compaction and direct compression. |
PubMed:Promising ternary dry powder inhaler formulations of cromolyn sodium: formulation and in vitro-in vivo evaluation. |
PubMed:Uniformity of poorly miscible powders determined by near infrared spectroscopy. |
PubMed:Dissolution improvement of four poorly water soluble drugs by cogrinding with commonly used excipients. |
PubMed:Enhancement of the dissolution of indomethacin in interactive mixtures using added fine lactose. |
PubMed:Evaluation of tablet formation of different lactoses by 3D modeling and fractal analysis. |
PubMed:Critical assessment of inverse gas chromatography as means of assessing surface free energy and acid-base interaction of pharmaceutical powders. |
PubMed:Stress relaxation test for the characterization of the viscoelasticity of pellets. |
PubMed:Effects of compression on the interaction between 1,4-dihydropyridine compounds and lactose monohydrate (II): differences in powder properties of 1,4-dihydropyridine compounds. |
PubMed:The influence of mechanical processing of dry powder inhaler carriers on drug aerosolization performance. |
PubMed:Insensitivity of compaction properties of brittle granules to size enlargement by roller compaction. |
PubMed:Influence of metronidazole particle properties on granules prepared in a high-shear mixer-granulator. |
PubMed:The effects of high shear blending on alpha-lactose monohydrate. |
PubMed:Influence of humidity on the electrostatic charge and aerosol performance of dry powder inhaler carrier based systems. |
PubMed:Resistance training with creatine monohydrate improves upper-body strength in patients with Parkinson disease: a randomized trial. |
PubMed:Nifedipine capsules may provide a viable alternative to oral powders for paediatric patients. |
PubMed:Determination of amorphous content in the pharmaceutical process environment. |
PubMed:Influence of realistic inspiratory flow profiles on fine particle fractions of dry powder aerosol formulations. |
PubMed:Triboelectrification of pharmaceutical powders by particle impact. |
PubMed:Continued investigation into the influence of loaded dose on the performance of dry powder inhalers: surface smoothing effects. |
PubMed:Humidity-induced changes of the aerodynamic properties of dry powder aerosol formulations containing different carriers. |
PubMed:Factorial designed experiment to study the effects of excipients on the mechanical properties of pellets. |
PubMed:The effect of poloxamer viscosity on liquid-filling of solid dispersions in hard gelatin capsules. |
PubMed:Electrostatic characterisation of inhaled powders: effect of contact surface and relative humidity. |
PubMed:Prediction of granule physical property by a novel compression energy of wet powder. |
PubMed:The effect of carrier surface treatment on drug particle detachment from crystalline carriers in adhesive mixtures for inhalation. |
PubMed:The nitrogen adsorption isotherm of alpha-lactose monohydrate. |
PubMed:Influence of water-cellulose binding energy on stability of acetylsalicylic acid. |
PubMed:Evaluation of melt granulation and ultrasonic spray congealing as techniques to enhance the dissolution of praziquantel. |
PubMed:The Gurnham equation in characterizing the compressibility of pharmaceutical materials. |
PubMed:The influence of drug-excipient and drug-polymer interactions on butt adhesive strength of ranitidine hydrochloride film-coated tablets. |
PubMed:[A study of the properties of tablets from mixtures of two size degrees of alpha-lactose monohydrate and microcrystalline cellulose]. |
PubMed:Novel temperature controlled surface dissolution of excipient particles for carrier based dry powder inhaler formulations. |
PubMed:Assessing the re-crystallization behaviour of amorphous lactose using the RH-perfusion cell. |
PubMed:Determination of the surface free energy of crystalline and amorphous lactose by atomic force microscopy adhesion measurement. |
PubMed:Effect of milling and sieving on functionality of dry powder inhalation products. |
PubMed:Excipient selection can significantly affect solid-state phase transformation in formulation during wet granulation. |
PubMed:The protective effect of lactose on lyophilization of CNK-20402. |
PubMed:Comparative study of erythritol and lactose monohydrate as carriers for inhalation: atomic force microscopy and in vitro correlation. |
PubMed:Tablets with high lactose content: effects of some binders and disintegrants on their properties. |
PubMed:Role of cellulose ether polymers on ibuprofen release from matrix tablets. |
PubMed:Effect of milling and compression on the solid-state Maillard reaction. |
PubMed:Agglomerate formation and growth mechanisms during melt agglomeration in a rotary processor. |
PubMed:Effect of a melt agglomeration process on agglomerates containing solid dispersions. |
PubMed:Differences between eccentric and rotary tablet machines in the evaluation of powder densification behaviour. |
PubMed:[A study of the properties of compacts from a mixed dry binder on the base of alpha-lactose monohydrate and microcrystalline cellulose]. |
PubMed:Comparison of the granulation behavior of three different excipients in a laboratory fluidized bed granulator using statistical methods. |
PubMed:Highly loaded interactive mixtures for dry powder inhalers: prediction of the adhesion capacity using surface energy and solubility parameters. |
PubMed:Measurement of lactose crystallinity using Raman spectroscopy. |
PubMed:Effect of compression on interaction between 1,4-dihydropyridine compounds and lactose monohydrate. |
PubMed:The effect of water to ethanol feed ratio on physical properties and aerosolization behavior of spray dried cromolyn sodium particles. |
PubMed:Structure determination of the stable anhydrous phase of alpha-lactose from X-ray powder diffraction. |
PubMed:A novel approach in the assessment of polymeric film formation and film adhesion on different pharmaceutical solid substrates. |
PubMed:The surface roughness of lactose particles can be modulated by wet-smoothing using a high-shear mixer. |
PubMed:Use of roughness maps in visualisation of surfaces. |
PubMed:Development of an enteric-coated pellet formulation of F4 fimbriae for oral vaccination of suckling piglets against enterotoxigenic Escherichia coli infections. |
PubMed:Crystallization and X-ray diffraction of spray-dried and freeze-dried amorphous lactose. |
PubMed:Development of a novel approach towards predicting the milling behaviour of pharmaceutical powders. |
PubMed:Search for technological reasons to develop a capsule or a tablet formulation with respect to wettability and dissolution. |
PubMed:Calcium sulphate dihydrate: an useful excipient for tablets containing labile actives. |
PubMed:The cohesive-adhesive balances in dry powder inhaler formulations I: Direct quantification by atomic force microscopy. |
PubMed:Investigations into the use of pregelatinised starch to develop powder-filled hard capsules. |
PubMed:Approaches to determine the enthalpy of crystallisation, and amorphous content, of lactose from isothermal calorimetric data. |
PubMed:Aerosolisation of beclomethasone dipropionate using spray dried lactose/polyethylene glycol carriers. |
PubMed:Compaction of crystallographic forms of pharmaceutical granular lactoses. II. Compacts mechanical properties. |
PubMed:Compaction of crystallographic forms of pharmaceutical granular lactoses. I. Compressibility. |
PubMed:Abrasive water jet cutting as a new procedure for cutting cancellous bone--in vitro testing in comparison with the oscillating saw. |
PubMed:Role of excipients in hydrate formation kinetics of theophylline in wet masses studied by near-infrared spectroscopy. |
PubMed:Comparison of torque measurements and near-infrared spectroscopy in characterization of a wet granulation process. |
PubMed:Ab initio structure determination of the hygroscopic anhydrous form of alpha-lactose by powder X-ray diffraction. |
PubMed:Quantifying low amorphous or crystalline amounts of alpha-lactose-monohydrate using X-ray powder diffraction, near-infrared spectroscopy, and differential scanning calorimetry. |
PubMed:Single-step granulation/tabletting of different grades of lactose: a comparison with high shear granulation and compression. |
PubMed:Influence of cellulose ether polymers on ketoprofen release from hydrophilic matrix tablets. |
PubMed:The 3D model: explaining densification and deformation mechanisms by using 3D parameter plots. |
PubMed:Functionality testing of inhalation grade lactose. |
PubMed:Endotoxin testing in inhalation grade lactose-a useful quality parameter? |
PubMed:The influence of carrier roughness on adhesion, content uniformity and the in vitro deposition of terbutaline sulphate from dry powder inhalers. |
PubMed:Melt pelletization with polyethylene glycol in a rotary processor. |
PubMed:Twin screw granulation as a simple and efficient tool for continuous wet granulation. |
PubMed:Energy-based analysis of milling alpha-lactose monohydrate. |
PubMed:Characterization and taste-masking evaluation of acetaminophen granules: comparison between different preparation methods in a high-shear mixer. |
PubMed:Optimization of the pelletization process in a fluid-bed rotor granulator using experimental design. |
PubMed:Method to recover a lipophilic drug from hydroxypropyl methylcellulose matrix tablets. |
PubMed:Cryopreservation of spermatozoa from closed colonies, and inbred, spontaneous mutant, and transgenic strains of rats. |
PubMed:Alternative sugars as potential carriers for dry powder inhalations. |
PubMed:Visualization of the crystallization of lactose from the amorphous state. |
PubMed:Moisture-induced surface crystallization of spray-dried amorphous lactose particles studied by atomic force microscopy. |
PubMed:A novel technique for imaging film coating defects in the film-core interface and surface of coated tablets. |
PubMed:The preparation of agglomerates containing solid dispersions of diazepam by melt agglomeration in a high shear mixer. |
PubMed:Development of agglomerated directly compressible diluent consisting of brittle and ductile materials. |
PubMed:The influence of carrier and drug morphology on drug delivery from dry powder formulations. |
PubMed:The relationship between granule growth mechanism, amount of liquid binder added and properties of the wet powder mass determined using a split bed shear tester. |
PubMed:Formulation design of carbamazepine fast-release tablets prepared by melt granulation technique. |
PubMed:Quantitative determination of crystallinity of alpha-lactose monohydrate by Near Infrared Spectroscopy (NIRS). |
PubMed:Influence of inverse gas chromatography measurement conditions on surface energy parameters of lactose monohydrate. |
PubMed:Effects of excipients on hydrate formation in wet masses containing theophylline. |
PubMed:Determining the compression behaviour of pharmaceutical powders from the force-distance compression profile. |
PubMed:Further investigations into the use of high sensitivity differential scanning calorimetry as a means of predicting drug-excipient interactions. |
PubMed:Influence of physico-chemical carrier properties on the in vitro aerosol deposition from interactive mixtures. |
PubMed:The in vitro dissolution of theophylline from different types of hard shell capsules. |
PubMed:Scaling-up of a lactose wet granulation process in Mi-Pro high shear mixers. |
PubMed:Predicting the quality of powders for inhalation from surface energy and area. |
PubMed:Wax beads as cushioning agents during the compression of coated diltiazem pellets. |
PubMed:Effects of ethanol to water ratio in feed solution on the crystallinity of spray-dried lactose. |
PubMed:The evaluation of the rheological properties of lactose/microcrystalline cellulose and water mixtures by controlled stress rheometry and the relationship to the production of spherical pellets by extrusion/spheronization. |
PubMed:The influence of relative humidity on particulate interactions in carrier-based dry powder inhaler formulations. |
PubMed:Dissolution kinetics of single crystals of alpha-lactose monohydrate. |
PubMed:Lactose modifications enhance its drug performance in the novel multiple dose Taifun DPI. |
PubMed:Effects of droplet size and type of binder on the agglomerate growth mechanisms by melt agglomeration in a fluidised bed. |
PubMed:Delivery of formoterol from a novel multi-dose inhaler Airmax. |
PubMed:Investigation of excipient type and level on drug release from controlled release tablets containing HPMC. |
PubMed:Clickhaler dry powder inhaler: focussed in vitro proof of principle evaluation of a new chemical entity for asthma. |
PubMed:Continuous twin screw extrusion for the wet granulation of lactose. |
PubMed:Dry powder inhaler: influence of humidity on topology and adhesion studied by AFM. |
PubMed:Determination of indomethacin crystallinity in the presence of excipients using diffuse reflectance near-infrared spectroscopy. |
PubMed:Lactose as a carrier in dry powder formulations: the influence of surface characteristics on drug delivery. |
PubMed:Cold extrusion as a continuous single-step granulation and tabletting process. |
PubMed:Melt agglomeration with polyethylene glycol beads at a low impeller speed in a high shear mixer. |
PubMed:Generation of live rat offspring by intrauterine insemination with epididymal spermatozoa cryopreserved at -196 degrees C. |
PubMed:Quantifying electrostatic interactions in pharmaceutical solid systems. |
PubMed:The determination of fracture mechanics properties of pharmaceutical materials in mode III loading using an anti-clastic plate bending method. |
PubMed:Alpha-lactose monohydrate single crystals as hosts for matrix isolation of guest biopolymers. |
PubMed:The bulk crystallization of alpha-lactose monohydrate from aqueous solution. |
PubMed:Quantifying amorphous content of lactose using parallel beam X-ray powder diffraction and whole pattern fitting. |
PubMed:The influence of excipients on the stability of the moisture sensitive drugs aspirin and niacinamide: comparison of tablets containing lactose monohydrate with tablets containing anhydrous lactose. |
PubMed:Characterisation and disintegration properties of irradiated starch. |
PubMed:The use of inverse phase gas chromatography to study the change of surface energy of amorphous lactose as a function of relative humidity and the processes of collapse and crystallisation. |
PubMed:Characterization of wet massing behavior of silicified microcrystalline cellulose and alpha-lactose monohydrate using near-infrared spectroscopy. |
PubMed:Drug-fatty acid salt with wax-like properties employed as binder in melt granulation. |
PubMed:The effects of carrier size and morphology on the dispersion of salbutamol sulphate after aerosolization at different flow rates. |
PubMed:Crystallization of lactose from carbopol gels. |
PubMed:High-resolution solid state 13C nuclear magnetic resonance spectra of 3,4-methylenedioxyamphetamine hydrochloride and related compounds and their mixtures with lactose. |
PubMed:Stability study of hard gelatin capsules containing retinoic acid. |
PubMed:The influence of crystallization conditions on the morphology of lactose intended for use as a carrier for dry powder aerosols. |
PubMed:The influence of carrier morphology on drug delivery by dry powder inhalers. |
PubMed:Direct pelletization in a rotary processor controlled by torque measurements. I. Influence of process variables. |
PubMed:Partial solubility parameters of lactose, mannitol and saccharose using the modified extended Hansen method and evaporation light scattering detection. |
PubMed:Pulmonary deposition of lactose carriers used in inhalation powders. |
PubMed:Influence of drying temperature and granulation liquid viscosity on the inter- and intragranular drug migration in tray-dried granules and compacts. |
PubMed:Influence of chopper and mixer speeds and microwave power level during the high-shear granulation process on the final granule characteristics. |
PubMed:Growth mechanisms in melt agglomeration with a low viscosity binder. |
PubMed:Compaction properties of composite particles consisting of lactose with sodium alginate prepared by spray-drying. |
PubMed:Electrostatic charging during a melt agglomeration process. |
PubMed:The application of multiple linear regression to the measurement of the median particle size of drugs and pharmaceutical excipients by near-infrared spectroscopy. |
PubMed:Near-infrared mass median particle size determination of lactose monohydrate, evaluating several chemometric approaches. |
PubMed:Investigations into the reduction of powder adhesion to stainless steel surfaces by surface modification to aid capsule filling. |
PubMed:The use of energy indices in estimating powder compaction functionality of mixtures in pharmaceutical tableting. |
PubMed:Supercritical fluid processing of materials from aqueous solutions: the application of SEDS to lactose as a model substance. |
PubMed:The use of particle characteristics to elucidate mix homogeneity in binary powder blends. |
PubMed:Crystallization and X-ray diffraction of crystals formed in water-plasticized amorphous lactose. |
PubMed:Protein deposition from dry powder inhalers: fine particle multiplets as performance modifiers. |
PubMed:Optimization of sustained-release tablet formulations: a four-component mixture experiment. |
PubMed:The development of a cascade impactor simulator based on adhesion force measurements to aid the development of dry powder inhalations. |
PubMed:Influence of Relative Humidity of Storage Air on the Adhesion and Autoadhesion of Micronized Particles to Particulate and Compacted Powder Surfaces |
PubMed:Modeling the crystal morphology of alpha-lactose monohydrate. |
PubMed:Development of a flow microcalorimetry method for the assessment of surface properties of powders. |
PubMed:[Determination of partial solubility parameters of lactoses and its application to solubility evaluation]. |
PubMed:Correlation of extrusion forces, raw materials and sphere characteristics. |
PubMed:Acoustic emission during the deformation of alpha-lactose monohydrate and anhydrous alpha-lactose monocrystals. |
PubMed:Influence of tabletting speed on compactibility and compressibility of two direct compressible powders under high speed compression. |
PubMed:Percolation theory and compactibility of binary powder systems. |
PubMed:NTP Toxicology and Carcinogenesis Studies of Pentaerythritol Tetranitrate (CAS No. 78-11-5) with 80% D-Lactose Monohydrate (PETN, NF) in F344/N Rats and B6C3F1 Mice (Feed Studies). |
PubMed:Optimization of a formulation for direct compression using a simplex lattice design. |
PubMed:Studies on tableting properties of lactose. Part III. The consolidation behaviour of sieve fractions of crystalline alpha-lactose monohydrate. |
PubMed:Oral lactose tolerance test in foals: technique and normal values. |
PubMed:Breath hydrogen test for lactose absorption capacity: importance of timing of hydrogen excretion and of high fasting hydrogen concentration. |
PubMed:Increased binding capacity and flowability of alpha-lactose monohydrate after dehydration. |
PubMed:A comparison of the effects of lactose and of two chemically modified waxy maize starches on mineral metabolism in the rat. |
PubMed:Radiation degradation of crystalline D-fructose and alpha-lactose monohydrate. |