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Category:natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Boiling Point: | 397.30 °C. @ 760.00 mm Hg (est)
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| Flash Point: | 357.00 °F. TCC ( 180.40 °C. ) (est)
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| logP (o/w): | 3.960 (est) |
| Soluble in: |
| | water, 17.61 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | natural substances and extractives |
| Recommendation for 4-methoxychalcone usage levels up to: | | | not for fragrance use.
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| Recommendation for 4-methoxychalcone flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | chalcone, 4-methoxy- (8CI) | | 4'- | methoxybenzylidene acetophenone | | para- | methoxyphenyl styryl ketone | | 3-(4- | methoxyphenyl)-1-phenyl-2-propen-1-one | | 3-(4- | methoxyphenyl)-1-phenylprop-2-en-1-one | | | phenyl p-methoxystyryl ketone | | 2- | propen-1-one, 3-(4-methoxyphenyl)-1-phenyl- (9CI) |
Articles:
| PubMed:Two new chalcones from Clerodendrum phlomidis. |
| PubMed:In vitro action of flavonoids in the canine malignant histiocytic cell line DH82. |
| PubMed:Antimalarial activity of 4-metoxychalcones: docking studies as falcipain/plasmepsin inhibitors, ADMET and lipophilic efficiency analysis to identify a putative oral lead candidate. |
| PubMed:4-methoxychalcone enhances cisplatin-induced oxidative stress and cytotoxicity by inhibiting the Nrf2/ARE-mediated defense mechanism in A549 lung cancer cells. |
| PubMed:Novel acetylated chalcone and biflavonoid glycosides from Trigonosciadium brachytaenium (Boiss.) Alava. |
| PubMed:4,2',5'-trihydroxy-4'-methoxychalcone from Dalbergia odorifera exhibits anti-inflammatory properties by inducing heme oxygenase-1 in murine macrophages. |
| PubMed:2-Hydroxychalcone and xanthohumol inhibit invasion of triple negative breast cancer cells. |
| PubMed:2-hydroxy-4'-methoxychalcone inhibits proliferation and inflammation of human aortic smooth muscle cells by increasing the expression of peroxisome proliferator-activated receptor gamma. |
| PubMed:Kinetic analysis of some chalcones and synthetic chalcone analogues on the fenton-reaction initiated deoxyribose degradation assay. |
| PubMed:Two new chalcone glycosides from the stems of Entada phaseoloides. |
| PubMed:PPARĪ± activation by culinary herbs and spices. |
| PubMed:Chalcones and dihydrochalcones augment TRAIL-mediated apoptosis in prostate cancer cells. |
| PubMed:Leishmania amazonensis growth inhibitors: biological and theoretical features of sulfonamide 4-methoxychalcone derivatives. |
| PubMed:Methoxy- and fluoro-chalcone derivatives arrest cell cycle progression and induce apoptosis in human melanoma cell A375. |
| PubMed:Altered sterol profile induced in Leishmania amazonensis by a natural dihydroxymethoxylated chalcone. |
| PubMed:Flavonoids from the heartwood of Dalbergia odorifera and their protective effect on glutamate-induced oxidative injury in HT22 cells. |
| PubMed:Lead compounds for anti-inflammatory drugs isolated from the plants of the traditional oriental medicine in Korea. |
| PubMed:Synthesis, biological evaluation and SAR of sulfonamide 4-methoxychalcone derivatives with potential antileishmanial activity. |
| PubMed:Phytochemical investigation of Anaphalis lactea. |
| PubMed:Allergy-preventive flavonoids from Xanthorrhoea hastilis. |
| PubMed:Analysis of antioxidant activities contained in the Boesenbergia pandurata Schult. Rhizome. |
| PubMed:Anti-angiogenic and anti-tumor activities of 2'-hydroxy-4'-methoxychalcone. |
| PubMed:A new chromone from Ficus lyrata. |
| PubMed:Inhibition of lipopolysaccharide-induced expression of inducible nitric oxide synthase and tumor necrosis factor-alpha by 2'-hydroxychalcone derivatives in RAW 264.7 cells. |
| PubMed:Inclusion compounds of 2,5-diphenylhydroquinone. |
| PubMed:Inhibition of prostalglandin E2 production by 2'-hydoxychalcone derivatives and the mechanism of action. |
| PubMed:Androechin, a new chalcone glucoside from Andrographis echioides. |
| PubMed:In vitro leishmanicidal activity of naturally occurring chalcones. |
| PubMed:Improvement of in vitro and in vivo antileishmanial activities of 2', 6'-dihydroxy-4'-methoxychalcone by entrapment in poly(D,L-lactide) nanoparticles. |
| PubMed:Selective effect of 2',6'-dihydroxy-4'-methoxychalcone isolated from Piper aduncum on Leishmania amazonensis. |
| PubMed:Chalcones, myo-inositol and other novel inhibitors of pulmonary carcinogenesis. |
| PubMed:Cytotoxic effect of butein on human colon adenocarcinoma cell proliferation. |
| PubMed:Introduction of unnatural amino acids into chalcone isomerase. |
| PubMed:[Kinetics of the bacteriostatic activity of natural and synthetic chalcones on a strain of Staphylococcus aureus]. |
| PubMed:Metabolism and excretion of butein, 2',3,4-trihydroxychalcone, 3-O-methylbutein, 4-O-methylbutein and 2',4',4-trihydroxychalcone in the rat. |
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3D/inchi