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Category:natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Soluble in: |
| | water, 6.592e+004 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | natural substances and extractives |
| Recommendation for 1,2-cyclohexane diol usage levels up to: | | | not for fragrance use.
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| Recommendation for 1,2-cyclohexane diol flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | brenzcatechin | | | cyclohexane-1,2-diol | | 1,2- | cyclohexanediol | | 1,2- | dihydroxycyclohexane | | 2- | hydroxycyclohexanol |
Articles:
| PubMed:Practical synthesis of the C-ring precursor of paclitaxel from 3-methoxytoluene. |
| PubMed:A Mild Catalytic Oxidation System: FePcOTf/H2O2 Applied for Cyclohexene Dihydroxylation. |
| PubMed:Encapsulation of enzyme via one-step template-free formation of stable organic-inorganic capsules: A simple and efficient method for immobilizing enzyme with high activity and recyclability. |
| PubMed:A simple and convenient approach for preparing core-shell-like silica@nickel species nanoparticles: highly efficient and stable catalyst for the dehydrogenation of 1,2-cyclohexanediol to catechol. |
| PubMed:Effect of hydroxyl groups and rigid structure in 1,4-cyclohexanediol on percutaneous absorption of metronidazole. |
| PubMed:Isolation, characterization, and nuclease activity of biologically relevant chromium(V) complexes with monosaccharides and model diols. Likely intermediates in chromium-induced cancers. |
| PubMed:Assessment of the nuclear pore dilating agent trans-cyclohexane-1,2-diol in differentiated airway epithelium. |
| PubMed:Structural organization of the nuclear pore permeability barrier. |
| PubMed:Contribution of flavonoids and catechol to the reduction of ICAM-1 expression in endothelial cells by a standardised Willow bark extract. |
| PubMed:Cyclohexane-1,2-dione hydrolase from denitrifying Azoarcus sp. strain 22Lin, a novel member of the thiamine diphosphate enzyme family. |
| PubMed:Theoretical study of oxidation of cyclohexane diol to adipic anhydride by [Ru(IV)(O)(tpa)(H2O)]2+ complex (tpa ═ tris(2-pyridylmethyl)amine). |
| PubMed:Theoretical insights into heme-catalyzed oxidation of cyclohexane to adipic acid. |
| PubMed:Exceptional structural and mechanical flexibility of the nuclear pore complex. |
| PubMed:A very active cu-catalytic system for the synthesis of aryl, heteroaryl, and vinyl sulfides. |
| PubMed:Microwave-assisted Ullmann C-S bond formation: synthesis of the P38alpha MAPK clinical candidate VX-745. |
| PubMed:On the origins of kinetic resolution of cyclohexane-1,2-diols through stereoselective acylation by chiral tetrapeptides. |
| PubMed:Oxidation of cyclohexanediol derivatives with 12-tungstophosphoric acid-hydrogen peroxide system. |
| PubMed:From simple diols to carbohydrate derivatives of phenylarsonic acid. |
| PubMed:Oxidation of p-chlorotoluene and cyclohexene catalysed by polymer-anchored oxovanadium(IV) and copper(II) complexes of amino acid derived tridentate ligands. |
| PubMed:New strategies for nucleic acid delivery to conquer cellular and nuclear membranes. |
| PubMed:An interlaboratory comparison of methods used to assess antioxidant potentials. |
| PubMed:An unexpected co-crystal with a variable degree of order: 1:1 rac-1,2-cyclohexanediol/triphenylphosphine oxide. |
| PubMed:Advantages of synthesizing trans-1,2-cyclohexanediol in a continuous flow microreactor over a standard glass apparatus. |
| PubMed:Is adamantane a suitable substituent to pre-organize the acid orientation in E-selectin antagonists? |
| PubMed:Nuclear accumulation of plasmid DNA can be enhanced by non-selective gating of the nuclear pore. |
| PubMed:Solid-state compounds of stereoisomers: cis and trans isomers of 1,2-cyclohexanediol and 2,3-tetralindiol. |
| PubMed:Dovyalicin-type spermidine alkaloids from Dovyalis species. |
| PubMed:Zr(IV)-monosubstituted Keggin-type dimeric polyoxometalates: synthesis, characterization, catalysis of H2O2-based oxidations, and theoretical study. |
| PubMed:Hydrophobic and hydrophilic yoctowells. |
| PubMed:Biocatalytic production of enantiopure cyclohexane-trans-1,2-diol using extracellular lipases from Bacillus subtilis. |
| PubMed:Towards carbohydrate derivatives of the ReI(CO)3 fragment. |
| PubMed:Preparation and evaluation of a chiral stationary phase covalently bound with chiral pseudo-1 8-crown-6 ether having 1-phenyl-1,2-cyclohexanediol as a chiral unit. |
| PubMed:Determination of the mode and efficacy of the cross-linking of guar by borate using MAS 11B NMR of borate cross-linked guar in combination with solution 11B NMR of model systems. |
| PubMed:Synthesis of a new oxime and its application to the construction of a highly selective and sensitive Co(II) PVC-based membrane sensor. |
| PubMed:Absence of interactive effects of trans-1,2-cyclohexanediol, a major metabolite of the side-chain of candesartan cilexetil, on digoxin-induced arrhythmias in dogs. |
| PubMed:Tin(II) chloride catalyzed reactions of diazodiphenylmethane with vicinal diols in an aprotic solvent. The reactions with cis- and trans-1,2-cyclohexanediols and 1,2-propanediol. |
| PubMed:[Enantiomeric resolution of trans-1,2-disubstituted cyclopropane by high performance liquid chromatography]. |
| PubMed:Chiral separation of enantiomeric 1,2-diamines using molecular imprinting method and selectivity enhancement by addition of achiral primary amines into eluents. |
| PubMed:Electronic Effects in Asymmetric Catalysis: Structural Studies of Precatalysts and Intermediates in Rh-Catalyzed Hydrogenation of Dimethyl Itaconate and Acetamidocinnamic Acid Derivatives Using C(2)-Symmetric Diarylphosphinite Ligands. |
| PubMed:Photoinitiated catalysis in Nafion membranes containing palladium(II) meso-tetrakis(N-methyl-4-pyridyl)porphyrin and iron(III) meso-tetrakis-(2,6-dichlorophenyl)porphyrin for O2-mediated oxidations of alkenes. |
| PubMed:Expression of benzene dioxygenase from Pseudomonas putida ML2 in cis-1,2-cyclohexanediol-degrading pseudomonads. |
| PubMed:Asymmetric synthesis of alpha,alpha-disubstituted alpha-amino acids using (S,S)-cyclohexane-1,2-diol as a chiral auxiliary. |
| PubMed:Insight into acid-mediated asymmetric spirocyclization in the presence of a chiral diol. |
| PubMed:Stereochemical differentiation of cyclic glycols by ion-molecule reactions in a quadrupole mass spectrometer using dimethyl ether acetonitrile and 2-S-pyrrolidinemethanol |
| PubMed:Effect of ethanol on the urinary excretion of cyclohexanol and cyclohexanediols, biomarkers of the exposure to cyclohexanone, cyclohexane and cyclohexanol in humans. |
| PubMed:Biological monitoring of occupational exposure to cyclohexane by urinary 1,2- and 1,4-cyclohexanediol determination. |
| PubMed:Monitoring of occupational exposure to cyclohexanone by diffusive sampling and urinalysis. |
| PubMed:1,2- and 1,4-Cyclohexanediol: major urinary metabolites and biomarkers of exposure to cyclohexane, cyclohexanone, and cyclohexanol in humans. |
| PubMed:Simultaneous determination of cyclohexene oxide and its metabolites in rat plasma and urine by gas chromatography. |
| PubMed:Absorption, disposition kinetics, and metabolic pathways of cyclohexene oxide in the male Fischer 344 rat and female B6C3F1 mouse. |
| PubMed:Simple and sensitive determination of 2,3-butanediol in biological samples by gas chromatography with electron-capture detection. |
| PubMed:Modulation of superoxide anion generation by manoalide, arachidonic acid and staurosporine in liver infiltrated neutrophils in a rat model of endotoxemia. |
| PubMed:Metabolism and disposition of cyclohexanone oxime in male F-344 rats. |
| PubMed:Cyclohexane diester analogues of phorbol ester as potential activators of protein kinase C. |
| PubMed:Urinary excretion of cyclohexanediol, a metabolite of the solvent cyclohexanone, by infants in a special care unit. |
| PubMed:Saturated analogues of poison ivy allergens. Synthesis of trans,trans- and cis,trans-3-alkyl-1,2-cyclohexanediols and sensitizing properties in allergic contact dermatitis. |
| PubMed:The role of arginyl residues in estrogen receptor activation and transformation. |
| PubMed:Myo-inositol transport in Saccharomyces cerevisiae. |
| PubMed:A study on the mutagenic activity of styrene and styrene oxide. |
| PubMed:[Suitability of the O-diphenol oxidase test using catechol for the differentiation of Cryptococcus neoformans]. |
| PubMed:The metabolites of cyclohexylamine in man and certain animals. |
| PubMed:Comparison of metal-binding properties of trans-1,2-cyclohexanediol diphosphate and deacylated phosphoinositides. |
| PubMed:Cis-Cyclohexane-1,2-diol in the beaver gland. |
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3D/inchi