EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

omega-hydroxyemodin
9,10-anthracenedione, 1,3,8-trihydroxy-6-(hydroxymethyl)-

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CAS Number: 481-73-2Picture of molecule3D/inchi
FDA UNII: O2H2Z421AP
Nikkaji Web:J13.188A
XlogP3-AA:1.50 (est)
Molecular Weight:286.23990000
Formula:C15 H10 O6
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
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Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 672.30 °C. @ 760.00 mm Hg (est)
Flash Point: 706.00 °F. TCC ( 374.40 °C. ) (est)
logP (o/w): 3.380 (est)
Soluble in:
 water, 95.38 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
Citreorosein >97%
Odor: characteristic
Use: Citreorosein, a naturally occurring anthraquinone derivative isolated from Polygoni cuspidati radix, attenuates cyclooxygenase-2-dependent prostaglandin D2 generation by blocking Akt and JNK pathways in mouse bone marrow-derived mast cells, it represents Anti-inflammatory
Coompo
For experimental / research use only.
Citreorosein from Plants ≥96%
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for omega-hydroxyemodin usage levels up to:
 not for fragrance use.
 
Recommendation for omega-hydroxyemodin flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :361512
National Institute of Allergy and Infectious Diseases:Data
1,3,8-trihydroxy-6-(hydroxymethyl)anthracene-9,10-dione
Chemidplus:0000481732
 
References:
 1,3,8-trihydroxy-6-(hydroxymethyl)anthracene-9,10-dione
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):361512
Pubchem (sid):135227186
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C17810
HMDB (The Human Metabolome Database):HMDB34444
FooDB:FDB012851
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 polygonum cuspidatum
Search Trop Picture
 
Synonyms:
9,10-anthracenedione, 1,3,8-trihydroxy-6-(hydroxymethyl)-
 citreorosein
w-hydroxyemodin
1,3,8-trihydroxy-6-(hydroxymethyl)-9,10-anthracenedione
1,3,8-trihydroxy-6-(hydroxymethyl)-9,10-anthraquinone
1,3,8-trihydroxy-6-(hydroxymethyl)-9,10-dihydroanthracene-9,10-dione
1,3,8-trihydroxy-6-(hydroxymethyl)anthracene-9,10-dione
1,3,8-trihydroxy-6-hydroxymethyl anthraquinone
1,3,8-trihydroxy-6-hydroxymethylanthraquinone
 

Articles:

PubMed:Calmodulin inhibitors from Aspergillus stromatoides.
PubMed:Differences in pharmacokinetics and ex vivo antioxidant activity following intravenous and oral administrations of emodin to rats.
PubMed:Characterization of emodin metabolites in Raji cells by LC-APCI-MS/MS.
PubMed:Structural elucidation of in vitro metabolites of emodin by liquid chromatography-tandem mass spectrometry.
PubMed:Six immunosuppressive features from an ascomycete, Zopfiella longicaudata, found in a screening study monitored by immunomodulatory activity.
PubMed:Neuraminidase inhibitors from Reynoutria elliptica.
PubMed:Biotransformation of the anthraquinones emodin and chrysophanol by cytochrome P450 enzymes. Bioactivation to genotoxic metabolites.
PubMed:omega-Hydroxyemodin, a major hepatic metabolite of emodin in various animals and its mutagenic activity.
PubMed:Studies in the biochemistry of micro-organisms: Emodic acid (4:5:7-trihydroxyanthraquinone-2-carboxylic acid) and omega-hydroxyemodin (4:5:7-trihydroxy-2-(hydroxymethyl)-anthraquinone), metabolic products of a strain of Penicillium cyclopium Westling.
 
Notes:
metabolite of emodin. Found in roots of Polygonum cuspidatum (Japanese knotweed)
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