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Category:natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Boiling Point: | 425.00 °C. @ 760.00 mm Hg (est)
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| Flash Point: | 330.00 °F. TCC ( 165.40 °C. ) (est)
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| logP (o/w): | 4.300 |
| Soluble in: |
| | water, 22.2 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | natural substances and extractives |
| Recommendation for 5-hydroxyflavone usage levels up to: | | | not for fragrance use.
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| Recommendation for 5-hydroxyflavone flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 4H-1- | benzopyran-4-one, 5-hydroxy-2-phenyl- | | | flavone, 5-hydroxy- | | 5- | hydroxy-2-phenyl-4-benzopyrone | | 5- | hydroxy-2-phenylchromen-4-one | | | primuliten |
Articles:
| PubMed:Differences in the hydroxylation pattern of flavonoids alter their chemoprotective effect against direct- and indirect-acting mutagens. |
| PubMed:Evaluation of estrogenic potential of flavonoids using a recombinant yeast strain and MCF7/BUS cell proliferation assay. |
| PubMed:Hydroxyflavones as a new family of matrices for MALDI tissue imaging. |
| PubMed:Synthesis and characterization of some new complexes of magnesium (II) and zinc (II) with the natural flavonoid primuletin. |
| PubMed:Fluorescence behavior of (selected) flavonols: a combined experimental and computational study. |
| PubMed:Pyranoflavones: a group of small-molecule probes for exploring the active site cavities of cytochrome P450 enzymes 1A1, 1A2, and 1B1. |
| PubMed:Summation solute hydrogen bonding acidity values for hydroxyl substituted flavones determined by NMR spectroscopy. |
| PubMed:Mutagenicity of flavonoids assayed by bacterial reverse mutation (Ames) test. |
| PubMed:Novel copper-based therapeutic agent for anti-inflammatory: synthesis, characterization, and biochemical activities of copper(II) complexes of hydroxyflavone Schiff bases. |
| PubMed:Structure-function relationships of inhibition of human cytochromes P450 1A1, 1A2, 1B1, 2C9, and 3A4 by 33 flavonoid derivatives. |
| PubMed:Ultrasonic-assisted synthesis of chrysin derivatives linked with 1,2,3-triazoles by 1,3-dipolar cycloaddition reaction. |
| PubMed:Excited state intramolecular proton transfer in 3-hydroxy flavone and 5-hydroxy flavone: a DFT based comparative study. |
| PubMed:Effect of flavonoids on androgen and glucocorticoid receptors based on in vitro reporter gene assay. |
| PubMed:Metabolism and pharmacokinetics of 3,3',4',7-tetrahydroxyflavone (fisetin), 5-hydroxyflavone, and 7-hydroxyflavone and antihemolysis effects of fisetin and its serum metabolites. |
| PubMed:Microbial metabolism part 9. Structure and antioxidant significance of the metabolites of 5,7-dihydroxyflavone (chrysin), and 5- and 6-hydroxyflavones. |
| PubMed:Permeability profile estimation of flavonoids and other phenolic compounds by biopartitioning micellar capillary chromatography. |
| PubMed:A fluorescent fluoride ion probe based on a self-organized ensemble of 5-hydroxyflavone-Al(III) complex. |
| PubMed:Fragmentation of 3-hydroxyflavone; a computational and mass spectrometric study. |
| PubMed:Spectroscopic and theoretical studies of the Zn(II) chelation with hydroxyflavones. |
| PubMed:Time dependent density functional theory study of electronic absorption properties of lead(II) complexes with a series of hydroxyflavones. |
| PubMed:Towards a photophysical model for 5-hydroxyflavone. |
| PubMed:Phytoestrogens as inhibitors of fungal 17beta-hydroxysteroid dehydrogenase. |
| PubMed:Phytoestrogens as inhibitors of fungal 17beta-hydroxysteroid dehydrogenase. |
| PubMed:A photoaffinity probe designed for host-specific signal flavonoid receptors in phytopathogenic Peronosporomycete zoospores of Aphanomyces cochlioides. |
| PubMed:Inhibition of matrix metalloproteinase-2 and -9 activities by selected flavonoids. |
| PubMed:Vasorelaxing effects of flavonoids: investigation on the possible involvement of potassium channels. |
| PubMed:Biological effects of epicuticular flavonoids from Primula denticulata on human leukemia cells. |
| PubMed:7-OH-flavone is sulfated in the human liver and duodenum, whereas 5-OH-flavone and 3-OH-flavone are potent inhibitors of SULT1A1 activity and 7-OH-flavone sulfation rate. |
| PubMed:Determination of the structure for polysubstituted flavonoid and 6-C-glucosyl flavonoids using 13C-1H long range couplings. |
| PubMed:Aromatic hydroxylation and sulfation of 5-hydroxyflavone by Streptomyces fulvissimus. |
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3D/inchi