EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

laevo-mannitol
L-mannitol

Supplier Sponsors

Name:(2S,3S,4S,5S)-hexane-1,2,3,4,5,6-hexol
CAS Number: 643-01-6Picture of molecule3D/inchi
FDA UNII: Search
Nikkaji Web:J13.213F
Beilstein Number:1721907
MDL:MFCD00154039
XlogP3:-3.10 (est)
Molecular Weight:182.17278000
Formula:C6 H14 O6
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:information only not used for fragrances or flavors
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 494.00 to 495.00 °C. @ 760.00 mm Hg (est)
Flash Point: 558.00 °F. TCC ( 292.50 °C. ) (est)
logP (o/w): -3.262 (est)
Soluble in:
 alcohol
 water, 1e+006 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
L-Mannitol
Carbosynth
For experimental / research use only.
L-Mannitol
Santa Cruz Biotechnology
For experimental / research use only.
L-Mannitol
TCI AMERICA
For experimental / research use only.
L-Mannitol >96.0%(GC)
sds
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
information only not used for fragrances or flavors
Recommendation for laevo-mannitol usage levels up to:
 not for fragrance use.
 
Recommendation for laevo-mannitol flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :136460
National Institute of Allergy and Infectious Diseases:Data
(2S,3S,4S,5S)-hexane-1,2,3,4,5,6-hexol
Chemidplus:0000643016
 
References:
 (2S,3S,4S,5S)-hexane-1,2,3,4,5,6-hexol
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):136460
Pubchem (sid):135091180
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
Golm Metabolome Database:Search
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2905.43.0000
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
(2S,3S,4S,5S)-hexane-1,2,3,4,5,6-hexol
L-mannitol
 

Articles:

PubMed:High glucose induces Rho/ROCK-dependent visfatin and type I procollagen expression in rat primary cardiac fibroblasts.
PubMed:Co-fermentation of carbon sources by Enterobacter aerogenes ATCC 29007 to enhance the production of bioethanol.
PubMed:The stimulatory effect of mannitol on levan biosynthesis: Lessons from metabolic systems analysis of Halomonas smyrnensis AAD6(T.).
PubMed:Optimization of dairy sludge for growth of Rhizobium cells.
PubMed:GALNT2 expression is reduced in patients with Type 2 diabetes: possible role of hyperglycemia.
PubMed:High glucose induces upregulation of scavenger receptors and promotes maturation of dendritic cells.
PubMed:Fisetin inhibits hyperglycemia-induced proinflammatory cytokine production by epigenetic mechanisms.
PubMed:[Study on the differentially expressed microRNA of human retinal microvascular endothelial cells in high glucose environment by microRNA gene chip].
PubMed:[Effect of norcantharidin on the expression of FN, Col IV and TGF-β1 mRNA and protein in HK-2 cells induced by high glucose].
PubMed:[Effect of mycophenolate on expression of MCP-1 and fibronectin in human mesangial cells induced by high glucose].
PubMed:Anesthetic efficacy of combinations of 0.5 mol/L mannitol and lidocaine with epinephrine for inferior alveolar nerve blocks in patients with symptomatic irreversible pulpitis.
PubMed:Medium optimization for enhanced co-production of two bioactive metabolites in the same fermentation by a statistical approach.
PubMed:[The effect of fasudil via Rho/ROCK signaling pathway on the inflammation and fibrosis in human mesangial cells in high glucose medium].
PubMed:[Connective tissue growth factor mediates high glucose-induced down-regulation of podocalyxin expression in mouse podocytes].
PubMed:Use of glycerol for producing 1,3-dihydroxyacetone by Gluconobacter oxydans in an airlift bioreactor.
PubMed:[Effects of high glucose on expression of core binding factor alpha1 and osteocalcin in vascular smooth muscle cells].
PubMed:[Effect of high concentration of glucose on thickness of glycocalyx and expression of syndecan-1 and glypican-1 in cultured human renal glomerular endothelial cells].
PubMed:Red blood cell hemolysis during blood bank storage: using national quality management data to answer basic scientific questions.
PubMed:[Effects of small interfering RNA targeting connective tissue growth factor on high glucose-induced human tubular epithelial hypertrophy].
PubMed:Selective inhibition of protein kinase C beta(2) attenuates inducible nitric oxide synthase-mediated cardiovascular abnormalities in streptozotocin-induced diabetic rats.
PubMed:[Effect of high glucose on PKC and MMPs/TIMPs in human mesangial cells].
PubMed:Transformation of isolated barley (Hordeum vulgare L.) microspores: II. Timing of pretreatment and temperatures relative to results of bombardment.
PubMed:Transformation of isolated barley (Hordeum vulgare L.) microspores: I. the influence of pretreatments and osmotic treatment on the time of DNA synthesis.
PubMed:[Somatic hybridization between Brassica napus and Eruca sativa mill].
PubMed:A method to co-encapsulate gas and drugs in liposomes for ultrasound-controlled drug delivery.
PubMed:[Comparison of the burn wound and diabetic ulcer wound].
PubMed:[Effect of different glucose concentrations on the expressions of insig-1 and insig-2 mRNA during the differentiation of 3T3-L1 cells].
PubMed:Effects of mycophenolic Acid on high glucose-induced fibronectin secretion and cellular reactive oxygen species in rat vascular smooth muscle cells.
PubMed:Polyol conversion specificity of Bacillus pallidus.
PubMed:1-De-oxy-l-mannitol (6-de-oxy-l-mannitol or l-rhamnitol).
PubMed:Mannitol upregulates monocyte HLA-DR, monocyte and neutrophil CD11b, and inhibits neutrophil apoptosis.
PubMed:[Effects of losartan on expressions of plasminogen activator and plasminogen activator inhibitor-1 of rat proximal tubular epithelial cells cultured with high glucose].
PubMed:Src family tyrosine kinases mediate contraction of rat isolated tail arteries in response to a hyposmotic stimulus.
PubMed:Generation of antibodies specific to D-mannitol, a unique haptenic allergen, using reductively aminated D-mannose-bovine serum albumin conjugate as the immunogen.
PubMed:[Protoplast culture and plant regeneration of the methionine resistant variant of Astragalus cicer L].
PubMed:Isolation, culture, and plant regeneration from Echinacea purpurea protoplasts.
PubMed:[Effects and mechanism of hyperglycemia on development and maturation and immune function of human monocyte derived dendritic cells].
PubMed:L-arginine supplementation prevents the development of endothelial dysfunction in hyperglycaemia.
PubMed:High glucose-induced inhibition of 2-deoxyglucose uptake is mediated by cAMP, protein kinase C, oxidative stress and mitogen-activated protein kinases in mouse embryonic stem cells.
PubMed:Elevated glucose activates protein synthesis in cultured cardiac myocytes.
PubMed:Carbon and complex nitrogen source selection for secondary metabolite cultivation at the pilot scale.
PubMed:Synthesis of malarial plasmepsin inhibitors and prediction of binding modes by molecular dynamics simulations.
PubMed:Analysis of amino acids in individual wheat embryonic protoplast.
PubMed:Protoplast isolation of callus in Echinacea augustifolia.
PubMed:[Protoplast culture and plant regeneration of the methionine resistant variant of Astragalus melilotoides Pall].
PubMed:Enhanced production of recombinant proteins from plant cells by the application of osmotic stress and protein stabilization.
PubMed:Leptin kinetics during peritoneal dialysis in acutely uraemic rats.
PubMed:Anaphylaxis to excipient mannitol: evidence for an immunoglobulin E-mediated mechanism.
PubMed:Central nervous system entry of peripherally injected umbilical cord blood cells is not required for neuroprotection in stroke.
PubMed:Effect of NaCl and mannitol iso-osmotic stresses on proline and free polyamine levels in embryogenic Fraxinus angustifolia callus.
PubMed:Adding sodium and calcium ions to the contrast medium iodixanol reduced the risk of ventricular fibrillation during perfusion of the left coronary artery in pigs: effects of electrolytes, viscosity, and chemotoxicity of an isotonic perfusate.
PubMed:The metabolic role and evolution of L-arabinitol 4-dehydrogenase of Hypocrea jecorina.
PubMed:Osmotic induced stimulation of the reduction of the viability dye 2,3,5-triphenyltetrazolium chloride by maize roots and callus cultures.
PubMed:Glucose and mannitol have different effects on peritoneal morphology in chronically dialyzed rats.
PubMed:Electroencephalogram is activated by addition of pentobarbital in the isolated perfused head of the rat.
PubMed:Albumin and glucose effects on cell growth parameters, albumin uptake and Na(+)/H(+)-exchanger Isoform 3 in OK cells.
PubMed:High glucose activates the p38 MAPK pathway in cultured human peritoneal mesothelial cells.
PubMed:[Excretion ratio of lactulose and mannitol as intestinal permeability index in healthy Chinese volunteers].
PubMed:Age-related association of small intestinal mucosal enteropathy with nutritional status in rural Gambian children.
PubMed:Experimental study on photodynamic diagnosis of cancer mediated by chemiluminescence probe.
PubMed:Studies on the synthesis of a G-rich octaoligoisonucleotide (isoT)2(isoG)4(isoT)2 by the phosphotriester approach and its formation of G-quartet structure.
PubMed:Physical correlates of the ultrasonic reflectivity of lipid dispersions suitable as diagnostic contrast agents.
PubMed:[Influence of mannitol additive on DNA separation by capillary non-gel sieving electrophoresis].
PubMed:Glucose dialysate induces mitochondrial DNA damage in peritoneal mesothelial cells.
PubMed:Troglitazone suppresses the secretion of type I collagen by mesangial cells in vitro.
PubMed:High glucose dialysis solutions increase synthesis of vascular endothelial growth factors by peritoneal vascular endothelial cells.
PubMed:Reversibility of glucose-induced changes in mesangial cell extracellular matrix depends on the genetic background.
PubMed:Reduced vasorelaxant effect of carbon monoxide in diabetes and the underlying mechanisms.
PubMed:Three new saponins from Tribulus terrestris.
PubMed:High glucose inhibits glucose uptake in renal proximal tubule cells by oxidative stress and protein kinase C.
PubMed:Regulation of the Na+2Cl-K+ cotransporter in isolated rat colon crypts.
PubMed:Migration of transformed renal epithelial cells is regulated by K+ channel modulation of actin cytoskeleton and cell volume.
PubMed:Regulation of the Na+2Cl–K+ cotransporter in in vitro perfused rectal gland tubules of Squalus acanthias.
PubMed:Hypertonic cell shrinkage reduces the K+ conductance of rat colonic crypts.
PubMed:Substrate specificity of sheep liver sorbitol dehydrogenase.
PubMed:High concentration of glucose increases mitogenic responsiveness to heparin-binding epidermal growth factor-like growth factor in rat vascular smooth muscle cells.
PubMed:High glucose and hyperosmolarity increase secretion of interleukin-1 beta in cultured human aortic endothelial cells.
PubMed:Glucose-stimulated sodium transport by the human intestine during experimental cholera.
PubMed:Glucose-dependent interleukin 6 and tumor necrosis factor production by human peripheral blood monocytes in vitro.
PubMed:Preparation and structure-activity relationship of novel P1/P1'-substituted cyclic urea-based human immunodeficiency virus type-1 protease inhibitors.
PubMed:Calcium entry stimulated by swelling of Madin-Darby canine kidney cells.
PubMed:Mannitol prevents methionine sulphoxidation mediated electrophoretic heterogeneity of apolipoprotein A-I.
PubMed:Quencher-enhanced specificity of psoralen-photosensitized virus inactivation in platelet concentrates.
PubMed:Na+/H+ exchange mediates meal-stimulated ileal absorption.
PubMed:Acidemia and hypernatremia enhance postischemic recovery of excitation-contraction coupling.
PubMed:High glucose and hyperosmolality stimulate hepatocyte growth factor secretion from cultured human mesangial cells.
PubMed:Co-expression of an anion conductance pathway with Na(+)-glucose cotransport in rat renal brush-border membrane vesicles.
PubMed:Influence of growth conditions on production of capsular and extracellular polysaccharides by Rhizobium leguminosarum.
PubMed:[Electrofusion of two-cell embryos of rabbit and their developmental capacity in vitro].
PubMed:Liquid volume, Na+ and mannitol concentration in a hypertonic mannitol-Ringer hydrothorax.
PubMed:Virus sterilization in platelet concentrates with psoralen and ultraviolet A light in the presence of quenchers.
PubMed:[Oral contrast media for the magnetic resonance tomography of the abdomen. A clinical trial of the tolerance for gadolinium-DTPA].
PubMed:Hypertonicity in fused Madin-Darby canine kidney cells: transient rise in NaHCO3 followed by sustained KCl accumulation.
PubMed:Jejunal permeability to water and electrolytes in patients with chronic intrahepatic hypertension: evidence for a role of aldosterone.
PubMed:Reduction of cerebral NaCl concentration can abolish mineralocorticoid escape.
PubMed:[Gadolinium-DTPA as an oral contrast medium for MR tomography of the abdomen].
PubMed:Small-bowel origin of the signal for meal-induced jejunal absorption.
PubMed:Volume-regulatory potassium release from isolated perfused rat kidney.
PubMed:[Gadolinium-DTPA as an oral contrast medium in magnetic resonance tomography].
PubMed:Effect of amiloride on cell volume regulation in renal straight proximal tubules.
PubMed:Recolonization and colonization resistance of the large bowel after three methods of preoperative preparation of the gastrointestinal tract for elective colorectal surgery.
PubMed:Discoupling of excitation-contraction processes by urea treatment of frog skeletal muscle.
PubMed:Responses to hypertonic solutions in guinea-pig atria: changes in action potentials, force of contraction and calcium content.
PubMed:[Prograde colonic irrigation without disturbance of the water-electrolyte balance].
PubMed:Cerebral mechanisms influencing renal sodium excretion in dehydrated sheep.
PubMed:Improved enzymatic method for determining mannitol and its application to dog serum after mannitol infusion.
PubMed:[Post-haemorrhagic encephalopathy in cirrhosis. Prevention by digestive irrigation with 100 mg/l mannitol (author's transl)].
PubMed:A third dipeptide carrier system typified by l-prolyl-lhydroxyproline and independent of l-leucyl and beta-alanyl dipeptides in rat gut loops.
 
Notes:
None found
Please share your Comments.
Email Address:
Top of Page Home
Copyright © 1980-2021 The Good Scents Company (tgsc) ™ Disclaimer Privacy Policy