EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

isorhamnetin
4H-1-benzopyran-4-one, 3,5,7-trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-

Supplier Sponsors

CAS Number: 480-19-3Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:207-545-5
FDA UNII: 07X3IB4R4Z
Nikkaji Web:J1.543A
Beilstein Number:0044723
MDL:MFCD00017310
XlogP3:1.90 (est)
Molecular Weight:316.26604000
Formula:C16 H12 O7
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:cosmetic agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 599.40 °C. @ 760.00 mm Hg (est)
Flash Point: 442.00 °F. TCC ( 227.80 °C. ) (est)
logP (o/w): 1.760 (est)
Soluble in:
 water, 1122 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: skin protecting agents
 
Suppliers:
Alfa Biotechnology
For experimental / research use only.
Isorhamnetin 98%
BOC Sciences
For experimental / research use only.
Isorhamnetin 98%
Odor: characteristic
Use: Isorhamnetin isolated from the herbs of Typha orientalis Presl. It is efficacious in protecting hepatocytes against oxidative stress by Nrf2 activation and in inducing the expressions of its downstream genes. anti-tumor promoter;
ExtraSynthese
For experimental / research use only.
isoRhamnetin (HPLC) ≥99%
Glentham Life Sciences
Isorhamnetin
Santa Cruz Biotechnology
For experimental / research use only.
isoRhamnetin ≥98%
Sigma-Aldrich: Sigma
For experimental / research use only.
isoRhamnetin ≥95.0% (HPLC)
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intravenous-rat LD50 11100 mg/kg
Drugs in Japan Vol. 6, Pg. 63, 1982.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
cosmetic agents
Recommendation for isorhamnetin usage levels up to:
 not for fragrance use.
 
Recommendation for isorhamnetin flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :5281654
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
3,5,7-trihydroxy-2-(4-hydroxy-3-methoxyphenyl)chromen-4-one
Chemidplus:0000480193
RTECS:LK9275450 for cas# 480-19-3
 
References:
 3,5,7-trihydroxy-2-(4-hydroxy-3-methoxyphenyl)chromen-4-one
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):5281654
Pubchem (sid):134974340
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C10084
HMDB (The Human Metabolome Database):HMDB02655
FooDB:FDB000604
YMDB (Yeast Metabolome Database):YMDB01720
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 alfalfa
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 buckthorn sea buckthorn
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 buckthorn sea buckthorn fruit
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 chamomile sweet false chamomile plant
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 chickpea
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 chive
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 cress garden cress
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 dandelion flower
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 dill plant
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 dill weed
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 fennel
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 fenugreek
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 ginkgo biloba leaf
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 guava
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 hartwort
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 lemon flower
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 onion bulb
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 onion red onion
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 parsley
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 parsnip leaf
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 pollen
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 rugula leaf
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 tarragon
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 tarragon plant
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Synonyms:
4H-1-benzopyran-4-one, 3,5,7-trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-
isohamnetin
3'-methoxy-3,4',5,7-tetrahydroxyflavone
3'-methoxy-4',5,7-trihydroxyflavonol
3'-methoxyquercetin
3-methyl quercetin
3-methylquercetin
3'-methylquercetin
3'-O-methylquercetin
3-methylquercetine
 quercetin 3'-methyl ether
isorhamnetine
isorhamnetol
3,4',5,7-tetrahydroxy-3'-methoxy flavone
3,4',5,7-tetrahydroxy-3'-methoxy-flavone
3,4',5,7-tetrahydroxy-3'-methoxyflavone
3,5,7-trihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-benzopyrone
3,5,7-trihydroxy-2-(4-hydroxy-3-methoxy-phenyl)chromen-4-one
3,5,7-trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4-benzopyrone
3,5,7-trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one
3,5,7-trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-benzopyran-4-one
3,5,7-trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-chromen-4-one
3,5,7-trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-H-1-benzopyran-4-one
3,5,7-trihydroxy-2-(4-hydroxy-3-methoxyphenyl)chromen-4-one
 

Articles:

PubMed:Antioxidant and anti-inflammatory activity of a flavonoid-rich concentrate recovered from Opuntia ficus-indica juice.
PubMed:Modulation of (-)-epicatechin Metabolism by Co-administration with other Polyphenols in Caco-2 Cell Model.
PubMed:A food frequency questionnaire validated for estimating dietary flavonoid intake in an Australian population.
PubMed:Purification and characterization of flavonoids from the leaves of Zanthoxylum bungeanum and correlation between their structure and antioxidant activity.
PubMed:A metabonomic analysis of the effect of quercetin on toxicity induced by chronic exposure to low-level dichlorvos in rat plasma.
PubMed:Flavonol content, oil%, and fatty acid composition variability in seeds of Teramnus labialis and T. uncinatus accessions with nutraceutical potential.
PubMed:Chemical profile and antiacetylcholinesterase, antityrosinase, antioxidant and α-glucosidase inhibitory activity of Cynometra cauliflora L. leaves.
PubMed:Identification of new flavonols in hybrid grapes by combined liquid chromatography-mass spectrometry approaches.
PubMed:Specific localization of quercetin-3-O-glucuronide in human brain.
PubMed:Effects of antioxidants of bamboo leaves and flavonoids on 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) formation in chemical model systems.
PubMed:Modulation of Strawberry/Cranberry Phenolic Compounds Glucuronidation by Co-Supplementation with Onion: Characterization of Phenolic Metabolites in Rat Plasma Using an Optimized μSPE-UHPLC-MS/MS Method.
PubMed:Analysis of flavonoids and hydroxycinnamic acid derivatives in rapeseeds (Brassica napus L. var. napus) by HPLC-PDA--ESI(--)-MS(n)/HRMS.
PubMed:Analysis of the metabolites of isorhamnetin 3-O-glucoside produced by human intestinal flora in vitro by applying ultraperformance liquid chromatography/quadrupole time-of-flight mass spectrometry.
PubMed:Anti-proliferative effects of quercetin and catechin metabolites.
PubMed:Transport characteristics of isorhamnetin across intestinal Caco-2 cell monolayers and the effects of transporters on it.
PubMed:Components of foods inhibit a drug exporter, human multidrug and toxin extrusion transporter 1.
PubMed:Rapid method for the simultaneous determination of flavonol aglycones in food using u-HPLC coupled with heating block acidic hydrolysis.
PubMed:Flavonoids induce the expression of synaptic proteins, synaptotagmin, and postsynaptic density protein-95 in cultured rat cortical neuron.
PubMed:Cytotoxic effect against 3T3 fibroblasts cells of saffron floral bio-residues extracts.
PubMed:Metabolomic analysis of the polyphenols in germinating mung beans (Vigna radiata) seeds and sprouts.
PubMed:Bioactive components from flowers of Sambucus nigra L. increase glucose uptake in primary porcine myotube cultures and reduce fat accumulation in Caenorhabditis elegans.
PubMed:Antioxidant/prooxidant effects of α-tocopherol, quercetin and isorhamnetin on linoleic acid peroxidation induced by Cu(II) and H2O2.
PubMed:Evaluation of total phenolics, flavonoids and antioxidant activity of 18 Korean onion cultivars: a comparative study.
PubMed:Advanced knowledge of three important classes of grape phenolics: anthocyanins, stilbenes and flavonols.
PubMed:Flavonoids from the grains of C1/R-S transgenic rice, the transgenic Oryza sativa spp. japonica, and their radical scavenging activities.
PubMed:Relationship analysis between flavonoids structure and subcritical water extraction (SWE).
PubMed:Antioxidant and antimicrobial properties of phenolic rich fraction of Seabuckthorn (Hippophae rhamnoides L.) leaves in vitro.
PubMed:Evaluation of the cytotoxicity, genotoxicity and apoptotic induction of an aqueous extract of Achyrocline satureioides (Lam.) DC.
PubMed:Flavonoids induce the synthesis and secretion of neurotrophic factors in cultured rat astrocytes: a signaling response mediated by estrogen receptor.
PubMed:Identification, quantification and antioxidant activity of acylated flavonol glycosides from sea buckthorn (Hippophae rhamnoides ssp. sinensis).
PubMed:Selective inhibition of the cytochrome P450 isoform by hyperoside and its potent inhibition of CYP2D6.
PubMed:[Biologically active substances of plant origin. Flavonols and flavones: prevalence, dietary sourses and consumption].
PubMed:O-Methylated flavonol isorhamnetin prevents acute inflammation through blocking of NF-κB activation.
PubMed:Hyaluronidase inhibiting activity and radical scavenging potential of flavonols in processed onion.
PubMed:A targeted metabolomics approach to understand differences in flavonoid biosynthesis in red and yellow raspberries.
PubMed:Antioxidant capacity, polyphenolic content and tandem HPLC-DAD-ESI/MS profiling of phenolic compounds from the South American berries Luma apiculata and L. chequén.
PubMed:Antioxidant and anticancer activities of Chenopodium quinoa leaves extracts - in vitro study.
PubMed:Phenolic compounds from Jacaranda caroba (Vell.) A. DC.: approaches to neurodegenerative disorders.
PubMed:Enhanced profiling of flavonol glycosides in the fruits of sea buckthorn (Hippophae rhamnoides).
PubMed:Application of response surface methodology to optimise extraction of flavonoids from fructus sophorae.
PubMed:Potent α-glucosidase and protein tyrosine phosphatase 1B inhibitors from Artemisia capillaris.
PubMed:Evolution of flavonoids in Mouratón berries taken from both bunch halves.
PubMed:Polyphenolics composition of the leaves of Zanthoxylum bungeanum Maxim. grown in Hebei, China, and their radical scavenging activities.
PubMed:Development of a validated HPLC method for the simultaneous determination of flavonoids in Cuscuta chinensis Lam. by ultra-violet detection.
PubMed:Quantitative and Chemical Fingerprint Analysis for the Quality Evaluation of Receptaculum Nelumbinis by RP-HPLC Coupled with Hierarchical Clustering Analysis.
PubMed:Dietary fat increases quercetin bioavailability in overweight adults.
PubMed:Apple peel bioactive rich extracts effectively inhibit in vitro human LDL cholesterol oxidation.
PubMed:Antithrombotic and profibrinolytic activities of isorhamnetin-3-O-galactoside and hyperoside.
PubMed:Quantification of flavonoids in black rice by liquid chromatography-negative electrospray ionization tandem mass spectrometry.
PubMed:An optimized method for analysis of phenolic compounds in buds, leaves, and fruits of black currant ( Ribes nigrum L.).
PubMed:Studies on the antioxidant potential of flavones of Allium vineale isolated from its water-soluble fraction.
PubMed:Evaluation of the inhibitory effects of quercetin-related flavonoids and tea catechins on the monoamine oxidase-A reaction in mouse brain mitochondria.
PubMed:Screening and quantitative analysis of antioxidants in the fruits of Livistona chinensis R. Br using HPLC-DAD-ESI/MS coupled with pre-column DPPH assay.
PubMed:HPLC-MSn identification and quantification of flavonol glycosides in 28 wild and cultivated berry species.
PubMed:Antiadipogenic activity of isohamnetin 3-O-β-D-glucopyranoside from Salicornia herbacea.
PubMed:Inhibitory activity of coumarins from Artemisia capillaris against advanced glycation endproduct formation.
PubMed:Inhibitory effect of luteolin on estrogen biosynthesis in human ovarian granulosa cells by suppression of aromatase (CYP19).
PubMed:Isorhamnetin, A Flavonol Aglycone from Ginkgo biloba L., Induces Neuronal Differentiation of Cultured PC12 Cells: Potentiating the Effect of Nerve Growth Factor.
PubMed:Evaluation of flavonoids and enterolactone in overnight urine as intake biomarkers of fruits, vegetables and beverages in the Inter99 cohort study using the method of triads.
PubMed:Genistein as a potential inducer of the anti-atherogenic enzyme paraoxonase-1: studies in cultured hepatocytes in vitro and in rat liver in vivo.
PubMed:HPLC-DAD-MS/MS profiling of antioxidant flavonoid glycosides in sea buckthorn (Hippophae rhamnoides L.) seeds.
PubMed:Interference of flavonoids with enzymatic assays for the determination of free fatty acid and triglyceride levels.
PubMed:Phenolic composition and antioxidant activity of aqueous infusions from Capparis spinosa L. and Crithmum maritimum L. before and after submission to a two-step in vitro digestion model.
PubMed:Structural characterization of phenolics and betacyanins in Gomphrena globosa by high-performance liquid chromatography-diode array detection/electrospray ionization multi-stage mass spectrometry.
PubMed:Effects of Ginkgo biloba constituents on fruit-infesting behavior of codling moth (Cydia pomonella) in apples.
PubMed:Liquid chromatography-tandem mass spectrometry analysis allows the simultaneous characterization of C-glycosyl and O-glycosyl flavonoids in stingless bee honeys.
PubMed:Subcritical water extraction of antioxidant compounds from Seabuckthorn (Hippophae rhamnoides) leaves for the comparative evaluation of antioxidant activity.
PubMed:Effects of O-methylated metabolites of quercetin on oxidative stress, thermotolerance, lifespan and bioavailability on Caenorhabditis elegans.
PubMed:Enriched cereal bars are more effective in increasing plasma quercetin compared with quercetin from powder-filled hard capsules.
PubMed:Characterization of phenolic components in polar extracts of Eucalyptus globulus Labill. bark by high-performance liquid chromatography-mass spectrometry.
PubMed:Antioxidant and hepatoprotective activities of phenolic rich fraction of Seabuckthorn (Hippophae rhamnoides L.) leaves.
PubMed:Determination of cranberry phenolic metabolites in rats by liquid chromatography-tandem mass spectrometry.
PubMed:Comparative analyses of total phenols, antioxidant activity, and flavonol glycoside profile of cladode flours from different varieties of Opuntia spp.
PubMed:Extraction, partial characterization, and storage stability of β-glucosidase from propolis.
PubMed:Hydroxycinnamic acid amide derivatives, phenolic compounds and antioxidant activities of extracts of pollen samples from Southeast Brazil.
PubMed:Quercetin and isorhamnetin glycosides in onion (Allium cepa L.): varietal comparison, physical distribution, coproduct evaluation, and long-term storage stability.
PubMed:Isolation and identification of sea buckthorn (Hippophae rhamnoides) phenolics with antioxidant activity and α-glucosidase inhibitory effect.
PubMed:Identification of botanical biomarkers in Argentinean Diplotaxis honeys: flavonoids and glucosinolates.
PubMed:Response of glucosinolate and flavonoid contents and composition of Brassica rapa ssp. chinensis (L.) Hanelt to silica formulations used as insecticides.
PubMed:The flavonol isorhamnetin exhibits cytotoxic effects on human colon cancer cells.
PubMed:Simultaneous quantification of flavonoids and phenolic acids in plant materials by a newly developed isocratic high-performance liquid chromatography approach.
PubMed:Antioxidant, cytoprotective and antibacterial effects of Sea buckthorn (Hippophae rhamnoides L.) leaves.
PubMed:Determination of antioxidant constituents in cactus pear fruits.
PubMed:Free fruit at workplace intervention increases total fruit intake: a validation study using 24 h dietary recall and urinary flavonoid excretion.
PubMed:Inhibitory effects of quercetin on aflatoxin B1-induced hepatic damage in mice.
PubMed:Effect of quercetin and its metabolites isorhamnetin and quercetin-3-glucuronide on inflammatory gene expression: role of miR-155.
PubMed:Phenolic component profiles of mustard greens, yu choy, and 15 other brassica vegetables.
PubMed:A detailed survey of seed coat flavonoids in developing seeds of Brassica napus L.
PubMed:Absorption and tissue distribution of dietary quercetin and quercetin glycosides of apple skin in broiler chickens.
PubMed:Almond (Prunus dulcis (Mill.) D.A. Webb) polyphenols: from chemical characterization to targeted analysis of phenolic metabolites in humans.
PubMed:Effect of quercetin on paraoxonase 1 activity--studies in cultured cells, mice and humans.
PubMed:Identification of bioactive compounds from flowers of black elder (Sambucus nigra L.) that activate the human peroxisome proliferator-activated receptor (PPAR) gamma.
PubMed:First report of non-coloured flavonoids in Echium plantagineum bee pollen: differentiation of isomers by liquid chromatography/ion trap mass spectrometry.
PubMed:Tomato ( Lycopersicon esculentum ) seeds: new flavonols and cytotoxic effect.
PubMed:Quercetin and isorhamnetin in sweet and red cultivars of onion (Allium cepa L.) at harvest, after field curing, heat treatment, and storage.
PubMed:Flavonol glycosides of sea buckthorn (Hippophaë rhamnoides ssp. sinensis) and lingonberry (Vaccinium vitis-idaea) are bioavailable in humans and monoglucuronidated for excretion.
PubMed:Preparative isolation and purification of four flavonoids from the petals of Nelumbo nucifera by high-speed counter-current chromatography.
PubMed:Anthocyanin and flavonol variation in bog bilberries (Vaccinium uliginosum L.) in Finland.
PubMed:Effect of quercetin on paraoxonase 2 levels in RAW264.7 macrophages and in human monocytes--role of quercetin metabolism.
PubMed:Profile of plasma and urine metabolites after the intake of almond [Prunus dulcis (Mill.) D.A. Webb] polyphenols in humans.
PubMed:Anatomical, chemical, and biochemical characterization of cladodes from prickly pear [Opuntia ficus-indica (L.) Mill.].
PubMed:Simultaneous determination of phenolic acids and flavonoids in Lycium barbarum Linnaeus by HPLC-DAD-ESI-MS.
PubMed:Pressurised liquid extraction of flavonoids in onions. Method development and validation.
PubMed:The relationship between fasting plasma concentrations of selected flavonoids and their ordinary dietary intake.
PubMed:Metabolic and bioactivity insights into Brassica oleracea var. acephala.
PubMed:Effect of dietary quercetin on brain quercetin levels and the expression of antioxidant and Alzheimer's disease relevant genes in mice.
PubMed:Evaluation of Salicornia herbacea as a potential antioxidant and anti-inflammatory agent.
PubMed:Effect of processing on the flavonoid content and antioxidant capacity of Citrus hystrix leaf.
PubMed:Analysis of phytochemical composition and chemoprotective capacity of rocket (Eruca sativa and Diplotaxis tenuifolia) leafy salad following cultivation in different environments.
PubMed:Protective effect of isorhamnetin 3-O-beta-D-glucopyranoside from Salicornia herbacea against oxidation-induced cell damage.
PubMed:Antioxidant properties of isolated isorhamnetin from the sea buckthorn marc.
PubMed:Effect of a low dose of sea buckthorn berries on circulating concentrations of cholesterol, triacylglycerols, and flavonols in healthy adults.
PubMed:Inhibitory activity of quercetin and its metabolite on lipopolysaccharide-induced activation of macrophage U937 cells.
PubMed:Modulation of Akt, JNK, and p38 activation is involved in citrus flavonoid-mediated cytoprotection of PC12 cells challenged by hydrogen peroxide.
PubMed:Effect of different organic farming methods on the phenolic composition of sea buckthorn berries.
PubMed:Antioxidant effects of flavonoid from Croatian Cystus incanus L. rich bee pollen.
PubMed:Flavonol 3-O-glycosides series of Vitis vinifera Cv. Petit Verdot red wine grapes.
PubMed:Effect of apoE genotype and dietary quercetin on blood lipids and TNF-alpha levels in apoE3 and apoE4 targeted gene replacement mice.
PubMed:New phenolic compounds and antioxidant potential of Catharanthus roseus.
PubMed:Phenolic compounds and chromatographic profiles of pear skins (Pyrus spp.).
PubMed:Flavonoid content in fresh, home-processed, and light-exposed onions and in dehydrated commercial onion products.
PubMed:Daily quercetin supplementation dose-dependently increases plasma quercetin concentrations in healthy humans.
PubMed:Flavonoid profile of green asparagus genotypes.
PubMed:The changes of antioxidant defense system caused by quercetin administration do not lead to DNA damage and apoptosis in the spleen and bone marrow cells of rats.
PubMed:Dietary flavonoid sources in Australian adults.
PubMed:Physiologically relevant metabolites of quercetin have no effect on adhesion molecule or chemokine expression in human vascular smooth muscle cells.
PubMed:Multi-substrate flavonol O-glucosyltransferases from strawberry (Fragaria x ananassa) achene and receptacle.
PubMed:Spermidine and flavonoid conjugates from peanut (Arachis hypogaea) flowers.
PubMed:Antioxidant constituents in the dayflower (Commelina communis L.) and their alpha-glucosidase-inhibitory activity.
PubMed:Activation of EpRE-mediated gene transcription by quercetin glucuronides depends on their deconjugation.
PubMed:A comparative study of flavonoid compounds, vitamin C, and antioxidant properties of baby leaf Brassicaceae species.
PubMed:Microwave-assisted efficient extraction of different parts of Hippophae rhamnoides for the comparative evaluation of antioxidant activity and quantification of its phenolic constituents by reverse-phase high-performance liquid chromatography (RP-HPLC).
PubMed:Effect of pectin enhancement on plasma quercetin and fecal flora in rutin-supplemented mice.
PubMed:Onions: a source of unique dietary flavonoids.
PubMed:Anthocyanins and other polyphenolics in American elderberry (Sambucus canadensis) and European elderberry (S. nigra) cultivars.
PubMed:Identification of flavonoid diglycosides in several genotypes of asparagus from the Huétor-Tájar population variety.
PubMed:Comparative effects of quercetin and its predominant human metabolites on adhesion molecule expression in activated human vascular endothelial cells.
PubMed:Identification of flavonoids and hydroxycinnamic acids in pak choi varieties (Brassica campestris L. ssp. chinensis var. communis) by HPLC-ESI-MSn and NMR and their quantification by HPLC-DAD.
PubMed:Effects of flavonoid on calcium content in femoral tissue culture and parathyroid hormone-stimulated osteoclastogenesis in bone marrow culture in vitro.
PubMed:Onion flesh and onion peel enhance antioxidant status in aged rats.
PubMed:Radioprotective and antioxidant activity of fractionated extracts of berries of Hippophae rhamnoides.
PubMed:Urinary excretion of 13 dietary flavonoids and phenolic acids in free-living healthy subjects - variability and possible use as biomarkers of polyphenol intake.
PubMed:Antioxidant constituents and a new triterpenoid glycoside from Flos Lonicerae.
PubMed:Flavonol profiles of Vitis vinifera red grapes and their single-cultivar wines.
PubMed:Physiological effects of extraction juices from apple, grape, and red beet pomaces in rats.
PubMed:Metabolite profiling of grape: Flavonols and anthocyanins.
PubMed:Absorption of flavonols derived from sea buckthorn (Hippophaë rhamnoides L.) and their effect on emerging risk factors for cardiovascular disease in humans.
PubMed:Microclimate influence on mineral and metabolic profiles of grape berries.
PubMed:Rumex induratus leaves: interesting dietary source of potential bioactive compounds.
PubMed:Urinary flavonoids and phenolic acids as biomarkers of intake for polyphenol-rich foods.
PubMed:Determination of flavonoids and phenolics and their distribution in almonds.
PubMed:Characterization of flavonol conjugates in immature leaves of pak choi [Brassica rapa L. Ssp. chinensis L. (Hanelt.)] by HPLC-DAD and LC-MS/MS.
PubMed:Ontogenic profiling of glucosinolates, flavonoids, and other secondary metabolites in Eruca sativa (salad rocket), Diplotaxis erucoides (wall rocket), Diplotaxis tenuifolia (wild rocket), and Bunias orientalis (Turkish rocket).
PubMed:Isorhamnetin glycosides with free radical and ONOO-scavenging activities from the stamens of Nelumbo nucifera.
PubMed:Unravelling the total antioxidant capacity of pinotage wines: contribution of phenolic compounds.
PubMed:HPLC-DAD/MS characterization of flavonoids and hydroxycinnamic derivatives in turnip tops (Brassica rapa L. Subsp. sylvestris L.).
PubMed:[Human pregnane X receptor-mediated transcriptional regulation of cytochrome P450 3A4 by some phytochemicals].
PubMed:Antioxidant polyphenols in almond and its coproducts.
PubMed:Sweet and sour cherry phenolics and their protective effects on neuronal cells.
PubMed:Flavonol glucoside profile of southern Italian red onion (Allium cepa L.).
PubMed:Ingestion of quercetin inhibits platelet aggregation and essential components of the collagen-stimulated platelet activation pathway in humans.
PubMed:Cytoprotection by neutral fraction of tannat red wine against oxidative stress-induced cell death.
PubMed:Characterisation of flavonols in broccoli (Brassica oleracea L. var. italica) by liquid chromatography-uV diode-array detection-electrospray ionisation mass spectrometry.
PubMed:The protozoan Tetrahymena as a bioindicator to screen bioactive substances.
PubMed:Profiling glucosinolates, flavonoids, alkaloids, and other secondary metabolites in tissues of Azima tetracantha L. (Salvadoraceae).
PubMed:Effect of flavonoids and vitamin E on cyclooxygenase-2 (COX-2) transcription.
PubMed:Structural investigations of flavonol glycosides from sea buckthorn (Hippophaë rhamnoides) pomace by NMR spectroscopy and HPLC-ESI-MS(n).
PubMed:The type of sugar moiety is a major determinant of the small intestinal uptake and subsequent biliary excretion of dietary quercetin glycosides.
PubMed:Lipid peroxidation inhibitory compounds from daylily (Hemerocallis fulva) leaves.
PubMed:Effect of flavonoids on feeding preference and development of the crucifer pest Mamestra configurata Walker.
PubMed:Betacyanins and phenolic compounds from Amaranthus spinosus L. and Boerhavia erecta L.
PubMed:Quercetin metabolites downregulate cyclooxygenase-2 transcription in human lymphocytes ex vivo but not in vivo.
PubMed:Flavonols and anthocyanins of bush butter, Dacryodes edulis (G. Don) H.J. Lam, fruit. changes in their composition during ripening.
PubMed:Chemical characterization and biological effects of Sicilian Opuntia ficus indica (L.) mill. Fruit juice: antioxidant and antiulcerogenic activity.
PubMed:Structure-antioxidant efficiency relationships of phenolic compounds and their contribution to the antioxidant activity of sea buckthorn juice.
PubMed:Absorption and urinary excretion of quercetin, rutin, and alphaG-rutin, a water soluble flavonoid, in rats.
PubMed:Further isolation of peroxynitrite and 1,1-diphenyl-2-picrylhydrazyl radical scavenging isorhamnetin 7-O-glucoside from the leaves of Brassica juncea L.
PubMed:Variation in the flavonol glycoside composition of almond seedcoats as determined by maldi-tof mass spectrometry.
PubMed:Antioxidant activities and antitumor screening of extracts from cranberry fruit (Vaccinium macrocarpon).
PubMed:Varietal differences among the polyphenol profiles of seven table grape cultivars studied by LC-DAD-MS-MS.
PubMed:Chemical composition of shallot (Allium ascalonicum Hort.).
PubMed:Antioxidant effects of isorhamnetin 3,7-di-O-beta-D-glucopyranoside isolated from mustard leaf (Brassica juncea) in rats with streptozotocin-induced diabetes.
PubMed:Effect of quercetin and its conjugated metabolite on the hydrogen peroxide-induced intracellular production of reactive oxygen species in mouse fibroblasts.
PubMed:Detection of isorhamnetin glycosides in extracts of apples (Malus domestica cv. "Brettacher") by HPLC-PDA and HPLC-APCI-MS/MS.
PubMed:Flavonoids in human urine as biomarkers for intake of fruits and vegetables.
PubMed:Identification and quantification of flavonol glycosides in almond seedcoats using MALDI-TOF MS.
PubMed:Combination of lipids and emulsifiers enhances the absorption of orally administered quercetin in rats.
PubMed:Human metabolism of dietary flavonoids: identification of plasma metabolites of quercetin.
PubMed:Isolation and characterization of stelladerol, a new antioxidant naphthalene glycoside, and other antioxidant glycosides from edible daylily (hemerocallis) flowers.
PubMed:Determination of phenolic acids and flavonoids of apple and pear by high-performance liquid chromatography.
PubMed:Factors affecting flavonoids absorption.
PubMed:Role of endogenous flavonoids in resistance mechanism of Vigna to aphids.
PubMed:Bioavailability and metabolism of the flavonol quercetin in the pig.
PubMed:Antioxidative activity of flavonoids in stimulated human neutrophils.
PubMed:Prediction of dietary flavonol consumption from fasting plasma concentration or urinary excretion.
PubMed:LC-ESI-MS study of the flavonoid glycoside malonates of red clover (Trifolium pratense).
PubMed:Relationship among antioxidant activity, vasodilation capacity, and phenolic content of red wines.
PubMed:Inhibition of xanthine oxidase by flavonoids.
PubMed:Inhibitory effect of quercetin metabolites and their related derivatives on copper ion-induced lipid peroxidation in human low-density lipoprotein.
PubMed:Characterization of flavonoids as monofunctional or bifunctional inducers of quinone reductase in murine hepatoma cell lines.
PubMed:In vitro biotransformation of flavonoids by rat liver microsomes.
PubMed:The inhibition by flavonoids of 2-amino-3-methylimidazo[4,5-f]quinoline metabolic activation to a mutagen: a structure-activity relationship study.
PubMed:Flavonoid pigments in chalkhill blue (Lysandra coridon Poda) and other lycaenid butterflies.
PubMed:Mutagens in Japanese pickle identified as flavonoids.
PubMed:The flavonol glycosides in the fruit of Pyrus communis L. cultivar Bon Chrétien.
 
Notes:
Widespread flavonol found especially in bee pollen, chives, corn poppy leaves, garden cress, fennel, hartwort, red onions, pears, dillweed, parsley and tarragon
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