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cannabigerol
1,3-benzenediol, 2-(3,7-dimethyl-2,6-octadienyl)-5-pentyl-, (E)-

Supplier Sponsors

Name:2-[(2E)-3,7-dimethylocta-2,6-dienyl]-5-pentylbenzene-1,3-diol
CAS Number: 25654-31-3Picture of molecule3D/inchi
Other(deleted CASRN):26645-67-0
FDA UNII: J1K406072N
Nikkaji Web:J19.303H
XlogP3-AA:7.40 (est)
Molecular Weight:316.48444000
Formula:C21 H32 O2
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
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Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 470.40 °C. @ 760.00 mm Hg (est)
Flash Point: 405.00 °F. TCC ( 207.20 °C. ) (est)
logP (o/w): 7.470 (est)
Soluble in:
 water, 0.003756 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Alfa Biotechnology
For experimental / research use only.
Cannabigerol 98%
BOC Sciences
For experimental / research use only.
Cannabigerol
Carbosynth
For experimental / research use only.
Cannabigerol
Coompo
For experimental / research use only.
Cannabigerol from Plants ≥96%
Symrise
CBG, Cannabigerol
min. 99%
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for cannabigerol usage levels up to:
 not for fragrance use.
 
Recommendation for cannabigerol flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :5315659
National Institute of Allergy and Infectious Diseases:Data
2-[(2E)-3,7-dimethylocta-2,6-dienyl]-5-pentylbenzene-1,3-diol
Chemidplus:0025654313
 
References:
 2-[(2E)-3,7-dimethylocta-2,6-dienyl]-5-pentylbenzene-1,3-diol
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):5315659
Pubchem (sid):135115393
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C20219
HMDB (The Human Metabolome Database):Search
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 found in nature
 
Synonyms:
1,3-benzenediol, 2-(3,7-dimethyl-2,6-octadienyl)-5-pentyl-, (E)-
1,3-benzenediol, 2-[(2E)-3,7-dimethyl-2,6-octadien-1-yl]-5-pentyl-
2-[(2E)-3,7-dimethyl-2,6-octadien-1-yl]-5-pentyl-1,3-benzenediol
2-[(2E)-3,7-dimethyl-2,6-octadienyl]-5-pentyl-1,3-benzenediol
2-[(2E)-3,7-dimethylocta-2,6-dienyl]-5-pentylbenzene-1,3-diol
 

Articles:

PubMed:A cannabigerol derivative suppresses immune responses and protects mice from experimental autoimmune encephalomyelitis.
PubMed:Voltage-gated sodium (NaV) channel blockade by plant cannabinoids does not confer anticonvulsant effects per se.
PubMed:Enhancing the activity of cannabidiol and other cannabinoids in vitro through modifications to drug combinations and treatment schedules.
PubMed:Cannabinoid receptor signaling in progenitor/stem cell proliferation and differentiation.
PubMed:The effect of cannabichromene on adult neural stem/progenitor cells.
PubMed:Analysis of cannabis seizures in NSW, Australia: cannabis potency and cannabinoid profile.
PubMed:Epigenetic control of skin differentiation genes by phytocannabinoids.
PubMed:[Marihuana and cannobinoids as medicaments].
PubMed:Beneficial effect of the non-psychotropic plant cannabinoid cannabigerol on experimental inflammatory bowel disease.
PubMed:Analysis of cannabinoids in laser-microdissected trichomes of medicinal Cannabis sativa using LCMS and cryogenic NMR.
PubMed:Medical use of cannabis. Cannabidiol: a new light for schizophrenia?
PubMed:Effect of chronic exposure to rimonabant and phytocannabinoids on anxiety-like behavior and saccharin palatability.
PubMed:A cannabigerol quinone alleviates neuroinflammation in a chronic model of multiple sclerosis.
PubMed:Cannabinol and cannabidiol exert opposing effects on rat feeding patterns.
PubMed:Cannabinoid hyperemesis syndrome.
PubMed:Modulation of L-α-lysophosphatidylinositol/GPR55 mitogen-activated protein kinase (MAPK) signaling by cannabinoids.
PubMed:Phytocannabinoids as novel therapeutic agents in CNS disorders.
PubMed:Bioactive prenylogous cannabinoid from fiber hemp (Cannabis sativa).
PubMed:Molecular analysis of genetic fidelity in Cannabis sativa L. plants grown from synthetic (encapsulated) seeds following in vitro storage.
PubMed:Plasma and brain pharmacokinetic profile of cannabidiol (CBD), cannabidivarine (CBDV), Δ⁹-tetrahydrocannabivarin (THCV) and cannabigerol (CBG) in rats and mice following oral and intraperitoneal administration and CBD action on obsessive-compulsive behaviour.
PubMed:Nonpsychotropic cannabinoids, abnormal cannabidiol and canabigerol-dimethyl heptyl, act at novel cannabinoid receptors to reduce intraocular pressure.
PubMed:Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects.
PubMed:Cannabinoid actions at TRPV channels: effects on TRPV3 and TRPV4 and their potential relevance to gastrointestinal inflammation.
PubMed:Evaluation of the cyclooxygenase inhibiting effects of six major cannabinoids isolated from Cannabis sativa.
PubMed:Interaction between non-psychotropic cannabinoids in marihuana: effect of cannabigerol (CBG) on the anti-nausea or anti-emetic effects of cannabidiol (CBD) in rats and shrews.
PubMed:Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes.
PubMed:Detection of cannabigerol and its presumptive metabolite in human urine after Cannabis consumption.
PubMed:Antidepressant-like effect of delta9-tetrahydrocannabinol and other cannabinoids isolated from Cannabis sativa L.
PubMed:Cannabinoid receptor 1 binding activity and quantitative analysis of Cannabis sativa L. smoke and vapor.
PubMed:Evidence that the plant cannabinoid cannabigerol is a highly potent alpha2-adrenoceptor agonist and moderately potent 5HT1A receptor antagonist.
PubMed:Innovative development and validation of an HPLC/DAD method for the qualitative and quantitative determination of major cannabinoids in cannabis plant material.
PubMed:Cannabis smoke condensate II: influence of tobacco on tetrahydrocannabinol levels.
PubMed:Antibacterial cannabinoids from Cannabis sativa: a structure-activity study.
PubMed:Plant-derived cannabinoids modulate the activity of transient receptor potential channels of ankyrin type-1 and melastatin type-8.
PubMed:Isolation and characterization of new Cannabis constituents from a high potency variety.
PubMed:Cannabinoids inhibit human keratinocyte proliferation through a non-CB1/CB2 mechanism and have a potential therapeutic value in the treatment of psoriasis.
PubMed:Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma.
PubMed:Flavonoid glycosides and cannabinoids from the pollen of Cannabis sativa L.
PubMed:NMR assignments of the major cannabinoids and cannabiflavonoids isolated from flowers of Cannabis sativa.
PubMed:A chemotaxonomic analysis of cannabinoid variation in Cannabis (Cannabaceae).
PubMed:The inheritance of chemical phenotype in Cannabis sativa L.
PubMed:Cannabinoids in clinical practice.
PubMed:Capillary electrochromatography of cannabinoids.
PubMed:Synthesis and cytotoxic effects of deoxy-tomentellin.
PubMed:Boron trifluoride etherate on silica-A modified Lewis acid reagent (VII). Antitumor activity of cannabigerol against human oral epitheloid carcinoma cells.
PubMed:[Gas chromatographic analysis of cannabinoids on tandem columns].
PubMed:Comparative in vitro metabolism of the cannabinoids.
PubMed:In vitro metabolism of cannabigerol in several mammalian species.
PubMed:A comparison of the ocular and central effects of delta 9-tetrahydrocannabinol and cannabigerol.
PubMed:The inhibitory effects of cannabinoids, the active constituents of Cannabis sativa L. on human and rabbit platelet aggregation.
PubMed:Formation of similar species to carbon monoxide during hepatic microsomal metabolism of cannabidiol on the basis of spectral interaction with cytochrome P-450.
PubMed:Determination and characterization of a cannabinoid receptor in rat brain.
PubMed:Identification of a new chemotype in Cannabis sativa: cannabigerol-dominant plants, biogenetic and agronomic prospects.
PubMed:Cannabinoid inhibition of adenylate cyclase: relative activity of constituents and metabolites of marihuana.
PubMed:Activation of phospholipase A2 by cannabinoids. Lack of correlation with CNS effects.
PubMed:Intraocular pressure, ocular toxicity and neurotoxicity after administration of cannabinol or cannabigerol.
PubMed:Allergenic properties of naturally occurring cannabinoids.
PubMed:Direct antigonadal activity of cannabinoids: suppression of rat granulosa cell functions.
PubMed:Synthesis and antimicrobial activities of certain cannabichromene and cannabigerol related compounds.
PubMed:Intraocular pressure following systemic administration of cannabinoids.
PubMed:On the definition of cannabinoids: botanical? chemical? pharmacological?
PubMed:High-pressure liquid chromatography of cannabis. Quantitative analysis of acidic and neutral cannabinoids.
PubMed:Cannabinoids: influence on neurotransmitter uptake in rat brain synaptosomes.
PubMed:Chemical basis of hashish activity.
PubMed:Cannabigerol monomethyl ether, a new component of hemp.
PubMed:Identification and quantification of cannabinoids in Cannabis sativa L. plants by high performance liquid chromatography-mass spectrometry.
PubMed:Differences in receptor binding affinity of several phytocannabinoids does not explain their effects on neural cell cultures.
PubMed:Colon carcinogenesis is inhibited by the TRPM8 antagonist cannabigerol, a Cannabis-derived non-psychotropic cannabinoid.
PubMed:Neuroprotective Properties of Cannabigerol in Huntington's Disease: Studies in R6/2 Mice and 3-Nitropropionate-lesioned Mice.
 
Notes:
None found
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