Category:natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Assay: | 95.00 to 100.00
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Food Chemicals Codex Listed: | No |
Boiling Point: | 373.00 to 374.00 °C. @ 760.00 mm Hg (est)
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Flash Point: | 381.00 °F. TCC ( 193.70 °C. ) (est)
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logP (o/w): | 0.928 (est) |
Soluble in: |
| water, 2.709e+004 mg/L @ 25 °C (est) |
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
Not determined
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Dermal Toxicity: |
Not determined
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Category: | natural substances and extractives |
Recommendation for meta-coumaric acid usage levels up to: | | not for fragrance use.
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Recommendation for meta-coumaric acid flavor usage levels up to: |
| not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| cinnamic acid, m-hydroxy- | 3- | coumaric acid | m- | coumaric acid | 3- | hydroxycinnamic acid | m- | hydroxycinnamic acid | meta- | hydroxycinnamic acid | 3-(3- | hydroxyphenyl)-2-propenoic acid | 3-(3- | hydroxyphenyl)acrylic acid | 3-(3- | hydroxyphenyl)prop-2-enoic acid | 2- | propenoic acid, 3- (3-hydroxyphenyl)- | 2- | propenoic acid, 3-(3-hydroxyphenyl)- |
Articles:
PubMed:Catalytic activity of the two-component flavin-dependent monooxygenase from Pseudomonas aeruginosa toward cinnamic acid derivatives. |
PubMed:Assessment of the anti-invasion potential and mechanism of select cinnamic acid derivatives on human lung adenocarcinoma cells. |
PubMed:Antimicrobial activity of phenolic compounds identified in wild mushrooms, SAR analysis and docking studies. |
PubMed:Increasing antioxidant activity of procyanidin extracts from the pericarp of Litchi chinensis processing waste by two probiotic bacteria bioconversions. |
PubMed:Design, synthesis and biological evaluation of ferulic Acid amides as selective matrix metalloproteinase inhibitors. |
PubMed:Mesoporous silica SBA-15, a new adsorbent for bioactive polyphenols from red wine. |
PubMed:Characterization of hydroxycinnamic acid derivatives binding to bovine serum albumin. |
PubMed:Energetics and structural properties, in the gas phase, of trans-hydroxycinnamic acids. |
PubMed:A fast method using a new hydrophilic-lipophilic balanced sorbent in combination with ultra-high performance liquid chromatography for quantification of significant bioactive metabolites in wines. |
PubMed:Antimicrobial activity and phenolic content of natural site and micropropagated Limonium avei (De Not.) Brullo & Erben plant extracts. |
PubMed:The proglycation effect of caffeic acid leads to the elevation of oxidative stress and inflammation in monocytes, macrophages and vascular endothelial cells. |
PubMed:Spectroscopic implications of the electron donor-acceptor effect in the photoactive yellow protein chromophore. |
PubMed:Chemical composition of Solanum nigrum linn extract and induction of autophagy by leaf water extract and its major flavonoids in AU565 breast cancer cells. |
PubMed:[Systematic review on sodium ferulate for treatment of diabetic nephropathy]. |
PubMed:New CE-ESI-MS analytical method for the separation, identification and quantification of seven phenolic acids including three isomer compounds in virgin olive oil. |
PubMed:Mass spectrometric investigations of alpha- and beta-cyclodextrin complexes with ortho-, meta- and para-coumaric acids by negative mode electrospray ionization. |
PubMed:Phenolic acid nanoparticle formation in iron-containing aqueous solutions. |
PubMed:Chlorogenic acid and its metabolite m-coumaric acid evoke neurite outgrowth in hippocampal neuronal cells. |
PubMed:Reversed phase-HPLC for rapid determination of polyphenols in flowers of rose species. |
PubMed:Electrochemical behavior and antioxidant and prooxidant activity of natural phenolics. |
PubMed:In vitro antioxidant activity of coffee compounds and their metabolites. |
PubMed:Urinary excretion of 13 dietary flavonoids and phenolic acids in free-living healthy subjects - variability and possible use as biomarkers of polyphenol intake. |
PubMed:Catalytic activity, duplication and evolution of the CYP98 cytochrome P450 family in wheat. |
PubMed:Non-natural cinnamic acid derivatives as substrates of cinnamate 4-hydroxylase. |
PubMed:Highly efficient preparation of lipophilic hydroxycinnamates by solvent-free lipase-catalyzed transesterification. |
PubMed:Urinary flavonoids and phenolic acids as biomarkers of intake for polyphenol-rich foods. |
PubMed:Targeting antioxidative signal transduction and stress response system: control of pathogenic Aspergillus with phenolics that inhibit mitochondrial function. |
PubMed:Inhibitory effect of phenolic acids on the proliferation of 3T3-L1 preadipocytes in relation to their antioxidant activity. |
PubMed:The feruloyl esterase system of Talaromyces stipitatus: determining the hydrolytic and synthetic specificity of TsFaeC. |
PubMed:Isolation and characterization of Halomonas sp. strain IMPC, a p-coumaric acid-metabolizing bacterium that decarboxylates other cinnamic acids under hypersaline conditions. |
PubMed:A coumaroyl-ester-3-hydroxylase insertion mutant reveals the existence of nonredundant meta-hydroxylation pathways and essential roles for phenolic precursors in cell expansion and plant growth. |
PubMed:Determination of hydrogen peroxide scavenging activity of cinnamic and benzoic acids employing a highly sensitive peroxyoxalate chemiluminescence-based assay: structure-activity relationships. |
PubMed:Phenolic acid profiles in some small berries. |
PubMed:Identification of phenolics for control of Aspergillus flavus using Saccharomyces cerevisiae in a model target-gene bioassay. |
PubMed:Microbial metabolites of ingested caffeic acid are absorbed by the monocarboxylic acid transporter (MCT) in intestinal Caco-2 cell monolayers. |
PubMed:Absorption, metabolism, degradation and urinary excretion of rosmarinic acid after intake of Perilla frutescens extract in humans. |
PubMed:Synergistic effect of antioxidant phenolic acids on human phenolsulfotransferase activity. |
PubMed:Orally administered rosmarinic acid is present as the conjugated and/or methylated forms in plasma, and is degraded and metabolized to conjugated forms of caffeic acid, ferulic acid and m-coumaric acid. |
PubMed:Transepithelial transport of chlorogenic acid, caffeic acid, and their colonic metabolites in intestinal caco-2 cell monolayers. |
PubMed:Structural effects of phenolic acids on the transepithelial transport of fluorescein in caco-2 cell monolayers. |
PubMed:Identification of metabolites of (-)-epicatechin gallate and their metabolic fate in the rat. |
PubMed:Chlorogenic acid bioavailability largely depends on its metabolism by the gut microflora in rats. |
PubMed:Effects of phenolic acids on human phenolsulfotransferases in relation to their antioxidant activity. |
PubMed:Differential production of meta hydroxylated phenylpropanoids in sweet basil peltate glandular trichomes and leaves is controlled by the activities of specific acyltransferases and hydroxylases. |
PubMed:Determination of free and total phenolic acids in plant-derived foods by HPLC with diode-array detection. |
PubMed:Algal growth inhibition effects and inducement modes by plant-producing phenols. |
PubMed:Metabolites of orally administered Perilla frutescens extract in rats and humans. |
PubMed:Genetic organization and characteristics of the 3-(3-hydroxyphenyl)propionic acid degradation pathway of Comamonas testosteroni TA441. |
PubMed:Metabolism of rosmarinic acid in rats. |
PubMed:Inhibition of peroxynitrite dependent tyrosine nitration by hydroxycinnamates: nitration or electron donation? |
PubMed:A 3-(3-hydroxyphenyl)propionic acid catabolic pathway in Rhodococcus globerulus PWD1: cloning and characterization of the hpp operon. |
PubMed:Genetic characterization and expression in heterologous hosts of the 3-(3-hydroxyphenyl)propionate catabolic pathway of Escherichia coli K-12. |
PubMed:Properties of a Maize Glutathione S-Transferase That Conjugates Coumaric Acid and Other Phenylpropanoids. |
PubMed:Structure-activity relationship of caffeic acid analogues on xanthine oxidase inhibition. |
PubMed:The blocking effect of phenolic acid on N-nitrosomorpholine formation in vitro. |
PubMed:Allelopathic compounds in leaves ofGliricidia sepium (Jacq.) kunth ex walp. and its effect onSorghum vulgare L. |
PubMed:Characterization of bispecific caffeic acid/5-hydroxyferulic acid O-methyltransferase from aspen. |
PubMed:Purification and characterization of p-coumaroyl-D-glucose hydroxylase of sweet potato (Ipomoea batatas) roots. |
PubMed:Antimicrobial activity and inhibition of aflatoxin B1 formation by olive plant tissue constituents. |
PubMed:Kinetic study on the slow inhibition of epidermis tyrosinase by m-coumaric acid. |
PubMed:[Biliary excretion of choleretically active cinnamic acid derivatives in the rat]. |
PubMed:9,10-Dihydrophenanthrenes as phytoalexins of Orchidaceae. Biosynthetic studies in vitro and in vivo proving the route from L-phenylalanine to dihydro-m-coumaric acid, dihydrostilbene and dihydrophenanthrenes. |
PubMed:Short-term inhibition of fatty acid biosynthesis in isolated hepatocytes by mono-aromatic compounds. |
PubMed:Enzymatic hydroxylation of m-coumaric acid by mice liver hydroxylase. |
PubMed:Biosynthesis of phytoquinones. Biosynthetic origins of the nuclei and satellite methyl groups of plastoquinone, tocopherols and tocopherolquinones in maize shoots, bean shoots and ivy leaves. |
PubMed:Degradation of phenylalanine and tyrosine by Sporobolomyces roseus. |
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Coumaric acid is a hydroxycinnamic acid, an organic compound that is a hydroxy derivative of cinnamic acid. There are three isomers, o-coumaric acid, m-coumaric acid, and p-coumaric acid, that differ by the position of the hydroxy substitution of the phenyl group. p-Coumaric acid is the most abundant isomer of the three in nature. (Wikipedia)
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