EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

guaifenesin
guaiacolic acid, ester with glycerol

Supplier Sponsors

Name:3-(2-methoxyphenoxy)propane-1,2-diol
CAS Number: 93-14-1Picture of molecule3D/inchi
Other(deleted CASRN):12041-73-5
ECHA EINECS - REACH Pre-Reg:202-222-5
FDA UNII: 495W7451VQ
Nikkaji Web:J3.936E
Beilstein Number:2049375
MDL:MFCD00016873
XlogP3:1.40 (est)
Molecular Weight:198.21838000
Formula:C10 H14 O4
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:pharmaceuticals / chemical synthisis
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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US Patents:Search
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Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 78.50 °C. @ 760.00 mm Hg
Boiling Point: 356.77 °C. @ 760.00 mm Hg (est)
Flash Point: 337.00 °F. TCC ( 169.60 °C. ) (est)
logP (o/w): 1.390
Soluble in:
 water, 2904 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
American International Chemical, LLC.
Guaifenesin
BOC Sciences
For experimental / research use only.
Guaifenesin >98%
Odor: characteristic
Use: Guaifenesin is thought to act as an expectorant.
Carbosynth
For experimental / research use only.
rac guaifenesin
Glentham Life Sciences
Guaiacol glyceryl ether
Penta International
GUAIFENESIN USP
Sigma-Aldrich
For experimental / research use only.
Guaifenesin pharmaceutical secondary standard; traceable to USP and PhEur
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intravenous-dog LD50 335 mg/kg
Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 54, Pg. 688, 1958.

intramuscular-mouse LD50 2210 mg/kg
Oyo Yakuri. Pharmacometrics. Vol. 8, Pg. 429, 1974.

intraperitoneal-mouse LD50 495 mg/kg
"Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 398, 1972.

intravenous-mouse LD50 400 mg/kg
Oyo Yakuri. Pharmacometrics. Vol. 8, Pg. 429, 1974.

oral-mouse LD50 690 mg/kg
"Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 398, 1972.

oral-rabbit LD50 2553 mg/kg
Applied Therapeutics. Vol. 9, Pg. 55, 1967.

intramuscular-rat LD50 4000 mg/kg
BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Oyo Yakuri. Pharmacometrics. Vol. 8, Pg. 429, 1974.

intraperitoneal-rat LD50 1000 mg/kg
BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 191, Pg. 147, 1971.

intravenous-rat LD50 360 mg/kg
BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: DYSPNEA KIDNEY, URETER, AND BLADDER: HEMATURIA
Proceedings of the Society for Experimental Biology and Medicine. Vol. 85, Pg. 323, 1954.

oral-rat LD50 1510 mg/kg
BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA
Pharmacological Research Communications. Vol. 1, Pg. 413, 1969.

Dermal Toxicity:
subcutaneous-mouse LD50 800 mg/kg
AUTONOMIC NERVOUS SYSTEM: "SMOOTH MUSCLE RELAXANT (MECHANISM UNDEFINED, SPASMOLYTIC)"
Arzneimittel-Forschung. Drug Research. Vol. 15, Pg. 1355, 1965.

subcutaneous-rat LD50 2550 mg/kg
Drugs in Japan Vol. 6, Pg. 210, 1982.

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
pharmaceuticals / chemical synthisis
Recommendation for guaifenesin usage levels up to:
 not for fragrance use.
 
Recommendation for guaifenesin flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
ClinicalTrials.gov:search
Daily Med:search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):93-14-1
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :3516
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:1
3-(2-methoxyphenoxy)propane-1,2-diol
Chemidplus:0000093141
 
References:
 3-(2-methoxyphenoxy)propane-1,2-diol
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:93-14-1
Pubchem (cid):3516
Pubchem (sid):134972687
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEMBL:View
KEGG (GenomeNet):D00337
HMDB (The Human Metabolome Database):HMDB04998
FooDB:FDB023575
MedlinePlusSupp:View
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 actifed C
 actifed-C
 aeronesin
 aether glycerinoguaiacolicus
 amonidren
 amonidrin
 amonidron
 anti-tuss
 aresol
 balminil expectorant
 bayer select head & chest cold
 benylin-E
 breonesin
 brexin EX
 bronchol
 bronkaid caplets
 calmipan
 calmylin expectorant
isoclor expectorant C
 colrex
 congestac
 contac cough & sore throat formula
 contac cough formula
 coricidin syrup
 cortussin
 creson
 diabetic tussin EX
1,2-dihydroxy-3-(2-methoxyphenoxy)propane
 dilor G
 dilyn
 dimacol
 dorassin
 equicol
 fenesin
 flartussin
 gaiamar
 gecolate
 genatuss
 glycerin guaiacolate
 glycerin monoguaiacol ether
 glycerinmonoguaiacol ether
 glycero-guaiacol ether
 glycerol a-(2-methoxyphenyl) ether
 glycerol a-(o-methoxyphenyl) ether
 glycerol a-(o-methoxyphenyl)ether
 glycerol a-guaiacyl ether
 glycerol a-guiacyl ether
 glycerol a-monoguaiacol ether
 glycerol guaiacolate
 glycerol mono(2-methoxyphenyl) ether
 glycerol mono(2-methoxyphenyl)ether
 glycerol-a-monoguaiacol ether
a-glyceryl guaiacol ether
 glyceryl guaiacolate
a-glyceryl guaiacolate ether
 glyceryl guaiacyl ether
 glyceryl guaicolate
 glyceryl guiacolate
 glycodex
 glycotuss
 glytuss
 gnaifenesin
 guafensin
 guaia-rom
 guaiacol glycerin ether
 guaiacol glycerol ether
 guaiacol glyceryl ether
 guaiacolic acid, ester with glycerol
 guaiacuran
 guaiacyl glyceryl ether
 guaiamar
 guaianesin
 guaicol glycerine ether
 guaicol glyceryl ether
 guaiphenesine
 guaiphesin
 guajacol-a-glycerin-ether
 guajacol-a-glycerinether
 guajacuran
 guajamar
 guanar
 guayanesin
 guiaphenesin
 guiatuss
 gvaja
 halotussin
 histalet X tablets
 humabid
 humibid L.A
 humibid sprinkle
 hustodil
 hycotuss
 hytuss
 hytuss-2X
 kwelcof
 lufyllin-GG
 metfenossidiolo
3-(2-methoxy-phenoxy)-propane-1,2-diol
3-(2-methoxyphenoxy)-1, 2-propanediol
3-(2-methoxyphenoxy)-1,2-propane diol
3-(2-methoxyphenoxy)-1,2-propanediol
3-(o-methoxyphenoxy)-1,2-propanediol
3-(o-methoxyphenoxy)-propanediol-1,2
3-(2-methoxyphenoxy)propane-1,2-diol
3-o-methoxyphenoxypropane 1:2-diol
3-{[2-(methyloxy)phenyl]oxy}propane-1,2-diol
 metossipropandiolo
 mintosyl
 miocaina
 miocurin
 miorelax
 mucinex D
 mucostop
 muskurelax
 myocain
 myorelax
 myoscain
 naldecon senior EX
 naldecon-CX
 naldecon-DX
 naldecon-EX
 nasatab LA
 neothylline-GG
 neurotone
 oresol
 oreson
 organidin NR
 pneumomist
 pneumotussin HC
 polaramine expectorant
1,2-propanediol, 3- (o-methoxyphenoxy)-
1,2-propanediol, 3-(2-methoxyphenoxy)-
1,2-propanediol, 3-(o-methoxyphenoxy)-
1,2,3-propanetriol, ether with 2-methoxyphenol
 propanosedyl
 PV tussin tablet
 reduton
 relaxyl-G
 reorganin
 resil
 respenyl
 respil
 resyl
 ritussin
 robitussin CF
 robitussin cold & cough
 robitussin DM
 robitussin PE
 robitussin severe congestion
 ru-tuss DE tablets
 ru-tuss expectorant
 scot-tussin expectorant
 sinumist-SR
 sirotol
 slo-phyllin GG
 sudafed cold and cough
 sudafed cough syrup
 tedral expectorant
 tenntus
 theolair plus
 tolyn
 touro EX
 trecid
 triaminic
 tulyl
 tulyn
 tussar SF
 tussar-2
 tussi-organidin DM NR
 tussi-organidin DM-S NR
 tussi-organidin NR
 tussi-organidin-S NR
 uni-tussin
 

Articles:

PubMed:In vitro erosive effect of pediatric medicines on deciduous tooth enamel.
PubMed:Is extended-release guaifenesin no better than a placebo?
PubMed:Trapping of muscle relaxant methocarbamol degradation product by complexation with copper(II) ion: spectroscopic and quantum chemical studies.
PubMed:Acute Renal Failure after Ingestion of Guaifenesin and Dextromethorphan.
PubMed:Effect of body position on intra-abdominal pressures and abdominal perfusion pressures measured at three sites in horses anesthetized with short-term total intravenous anesthesia.
PubMed:Bioavailability of paracetamol, phenylephrine hydrochloride and guaifenesin in a fixed-combination syrup versus an oral reference product.
PubMed:Urological complications of illicit drug use.
PubMed:Role of mucolytics in wet cough.
PubMed:[Results of international multicentre non-interventional clinical study of the effectiveness and safety of ascoril expectorant for the treatment of cough in Kazakhstan and Uzbekistan].
PubMed:Desktop 3D printing of controlled release pharmaceutical bilayer tablets.
PubMed:A case of levocetirizine-induced fixed drug eruption and cross-reaction with piperazine derivatives.
PubMed:Propofol with ketamine following sedation with xylazine for routine induction of general anaesthesia in horses.
PubMed:Acute bilateral ureteral obstruction secondary to guaifenesin toxicity.
PubMed:Cardiorespiratory and antinociceptive effects of two different doses of lidocaine administered to horses during a constant intravenous infusion of xylazine and ketamine.
PubMed:Guaifenesin has no effect on sputum volume or sputum properties in adolescents and adults with acute respiratory tract infections.
PubMed:Honey plus coffee versus systemic steroid in the treatment of persistent post-infectious cough: a randomised controlled trial.
PubMed:Effects of ketamine, propofol, or thiopental administration on intraocular pressure and qualities of induction of and recovery from anesthesia in horses.
PubMed:The pharmacokinetics of methocarbamol and guaifenesin after single intravenous and multiple-dose oral administration of methocarbamol in the horse.
PubMed:Cardiovascular effects of dobutamine and phenylephrine infusion in sevoflurane-anesthetized Thoroughbred horses.
PubMed:Anticonvulsant Effect of Guaifenesin against Pentylenetetrazol-Induced Seizure in Mice.
PubMed:Guaifenesin derivatives promote neurite outgrowth and protect diabetic mice from neuropathy.
PubMed:[Rapid identification 15 effective components of anti common cold medicine with MRM by LC-MS/MS].
PubMed:Mechanisms of herb-induced nephrotoxicity.
PubMed:Swift onset of central nervous system depression and asystole followingan overdose of Guaifenesin.
PubMed:Balanced anesthesia and constant-rate infusions in horses.
PubMed:Characterization of the binding of metoprolol tartrate and guaifenesin drugs to human serum albumin and human hemoglobin proteins by fluorescence and circular dichroism spectroscopy.
PubMed:Determination of ambroxol hydrochloride, guaifenesin, and theophylline in ternary mixtures and in the presence of excipients in different pharmaceutical dosage forms.
PubMed:Hemodynamic effects of 6% hydroxyethyl starch infusion in sevoflurane-anesthetized thoroughbred horses.
PubMed:Effects of postanesthetic sedation with romifidine or xylazine on quality of recovery from isoflurane anesthesia in horses.
PubMed:Question: does guaifenesin improve outcomes in patients with cough associated with upper respiratory infection compared with no intervention?
PubMed:Patient-reported outcomes to assess the efficacy of extended-release guaifenesin for the treatment of acute respiratory tract infection symptoms.
PubMed:[Use of the mucoregulator ascoril for respiratory diseases].
PubMed:Influence of drugs on the response characteristics of the LiDCO sensor: an in vitro study.
PubMed:Effects of guaifenesin, N-acetylcysteine, and ambroxol on MUC5AC and mucociliary transport in primary differentiated human tracheal-bronchial cells.
PubMed:Prescribing patterns and safety of mezclitas for respiratory illnesses.
PubMed:Interaction of methocarbamol and yeast sucrase induces enzyme inhibition.
PubMed:Nebulized lidocaine in the treatment of intractable cough.
PubMed:Over-the-counter (OTC) medications for acute cough in children and adults in ambulatory settings.
PubMed:Alfaxalone compared with ketamine for induction of anaesthesia in horses following xylazine and guaifenesin.
PubMed:Simultaneous determination of methocarbamol and ibuprofen or diclofenac potassium using mean centering of the ratio spectra method.
PubMed:Evaluation of the clinical efficacy of two partial intravenous anesthetic protocols, compared with isoflurane alone, to maintain general anesthesia in horses.
PubMed:Pulsed delivery of inhaled nitric oxide counteracts hypoxaemia during 2.5 hours of inhalation anaesthesia in dorsally recumbent horses.
PubMed:Optimization of an improved single-column chromatographic process for the separation of enantiomers.
PubMed:Clinical evaluation of detomidine-butorphanol-guaifenesin-ketamine as short term TIVA in Spiti ponies.
PubMed:Stability-indicating HPLC Method for Simultaneous Determination of Terbutaline Sulphate, Bromhexine Hydrochloride and Guaifenesin.
PubMed:Anesthetic induction with guaifenesin and propofol in adult horses.
PubMed:Simultaneous determination of codeine, ephedrine, guaiphenesin and chlorpheniramine in beagle dog plasma using high performance liquid chromatography coupled with tandem mass spectrometric detection: application to a bioequivalence study.
PubMed:Application of hollow fiber-supported liquid-phase microextraction coupled with HPLC for the determination of guaifenesin enantiomer-protein binding.
PubMed:Effect of guaifenesin on mucin production, rheology, and mucociliary transport in differentiated human airway epithelial cells.
PubMed:Using dispersive liquid-liquid microextraction and liquid chromatography for determination of guaifenesin enantiomers in human urine.
PubMed:Development and validation of stability indicating the RP-HPLC method for the estimation of related compounds of guaifenesin in pharmaceutical dosage forms.
PubMed:Therapeutic options for acute cough due to upper respiratory infections in children.
PubMed:The pharmacokinetics and pharmacodynamics of the injectable anaesthetic alfaxalone in the horse.
PubMed:Clinical evaluation of total intravenous anesthesia using a combination of propofol and medetomidine following anesthesia induction with medetomidine, guaifenesin and propofol for castration in Thoroughbred horses.
PubMed:The role of decongestants, cromolyn, guafenesin, saline washes, capsaicin, leukotriene antagonists, and other treatments on rhinitis.
PubMed:Clinical Evaluation of Xylazine-Butorphanol-Guaifenesin-Ketamine as Short-Term TIVA in Equines.
PubMed:A new technique for spectrophotometric determination of pseudoephedrine and guaifenesin in syrup and synthetic mixture.
PubMed:Reproducibility of neutron activated Sm-153 oral dose formulations intended for human administration.
PubMed:Salivary cortisol in obstructive sleep apnea: the effect of CPAP.
PubMed:Recommendations for the proper use of nonprescription cough suppressants and expectorants in solid-organ transplant recipients.
PubMed:A combined desorption ionization by charge exchange (DICE) and desorption electrospray ionization (DESI) source for mass spectrometry.
PubMed:Modulating the synthetase activity of penicillin G acylase in organic media by addition of N-methylimidazole: using vinyl acetate as activated acyl donor.
PubMed:Guaifenesin and increased sperm motility: a preliminary case report.
PubMed:Nitric oxide donors improve prednisone effects on muscular dystrophy in the mdx mouse diaphragm.
PubMed:Influence of modified open lung concept ventilation on the cardiovascular and pulmonary function of horses during total intravenous anaesthesia.
PubMed:Simultaneous determination of potassium guaiacolsulfonate, guaifenesin, diphenhydramine HCl and carbetapentane citrate in syrups by using HPLC-DAD coupled with partial least squares multivariate calibration.
PubMed:Blockade of MUC1 expression by glycerol guaiacolate inhibits proliferation of human breast cancer cells.
PubMed:[The relationship between the lung function and the level of TNF-α in serum in COPD department of respiratory].
PubMed:Efficacy, safety and tolerability of salbutamol + guaiphenesin + bromhexine (Ascoril) expectorant versus expectorants containing salbutamol and either guaiphenesin or bromhexine in productive cough: a randomised controlled comparative study.
PubMed:Case report: anaphylactic reaction to guaifenesin.
PubMed:Ion mobility spectrometry for the rapid analysis of over-the-counter drugs and beverages.
PubMed:Simultaneous determination of diclofenac potassium and methocarbamol in ternary mixture with guaifenesin by reversed phase liquid chromatography.
PubMed:Clinical efficacy of farcosolvin syrup (ambroxol-theophylline-guaiphenesin mixture) in the treatment of acute exacerbation of chronic bronchitis.
PubMed:Sensitive spectrophotometric method for quantitation of guaifenesin and dropropizine in their dosage forms.
PubMed:Partial intravenous anaesthesia in 5 horses using ketamine, lidocaine, medetomidine and halothane.
PubMed:[A prospective multicenter randomized controlled clinical study on the efficacy and safety of Guaifenesin compound pseudoephedrine hydrochloride oral solution].
PubMed:Effects of adding butorphanol to a balanced anaesthesia protocol during arthroscopic surgery in horses.
PubMed:Experimental implementation of automatic 'cycle to cycle' control to a nonlinear chiral simulated moving bed separation.
PubMed:Pulmonary gas exchange in anaesthetised horses mechanically ventilated with oxygen or a helium/oxygen mixture.
PubMed:Laccase catalyzed covalent coupling of fluorophenols increases lignocellulose surface hydrophobicity.
PubMed:The influence of heterogeneous nucleation on the surface crystallization of guaifenesin from melt extrudates containing Eudragit L10055 or Acryl-EZE.
PubMed:Aqueous film coating to reduce recrystallization of guaifenesin from hot-melt extruded acrylic matrices.
PubMed:Do OTC remedies relieve cough in acute URIs?
PubMed:Guaifenesin enhances the analgesic potency of ibuprofen, nimesulide and celecoxib in mice.
PubMed:Best drugs for what ails you: the brands to buy--and those to skip.
PubMed:Oxidation of the erythro and threo forms of the phenolic lignin model compound 1-(4-hydroxy-3-methoxyphenyl)-2-(2-methoxyphenoxy)-1,3-propanediol by laccases and model oxidants.
PubMed:A sensitive liquid chromatography-electrospray ionization-mass spectrometry method for the simultaneous determination of pentoxyverine citrate and guaifenesin in human plasma---application to pharmacokinetic and bioequivalence studies.
PubMed:Safety and efficacy of extended-release guaifenesin/pseudoephedrine hydrochloride for adjunctive symptom relief of acute respiratory infections.
PubMed:Self-reported medication and herb/supplement use by women with and without fibromyalgia.
PubMed:Development of a nitric oxide-releasing analogue of the muscle relaxant guaifenesin for skeletal muscle satellite cell myogenesis.
PubMed:Simultaneous determination of pseudoephdrine, pheniramine, guaifenisin, pyrilamine, chlorpheniramine and dextromethorphan in cough and cold medicines by high performance liquid chromatography.
PubMed:Implementation of an automated on-line high-performance liquid chromatography monitoring system for 'cycle to cycle' control of simulated moving beds.
PubMed:Guaifenesin in rhinitis.
PubMed:Effect of mode of administration on guaifenesin pharmacokinetics and expectorant action in the rat model.
PubMed:Inhibition of cough-reflex sensitivity by benzonatate and guaifenesin in acute viral cough.
PubMed:Effects of changing body position on oxygenation and arterial blood pressures in foals anesthetized with guaifenesin, ketamine, and xylazine.
PubMed:Accidental dextromethorphan ingestions in children less than 5 years old.
PubMed:Screening and semiquantitative analysis of drugs and drugs of abuse in human serum samples using gas chromatography-mass spectrometry.
PubMed:A simple micellar electrokinetic capillary chromatographic method for the quantitative analysis of organic expectorants.
PubMed:Equine Anesthesia: Triple Drip.
PubMed:Cough and cold medication use by US children, 1999-2006: results from the slone survey.
PubMed:A randomized, double-blind, parallel-group, multicenter, placebo-controlled study of the safety and efficacy of extended-release guaifenesin/pseudoephedrine hydrochloride for symptom relief as an adjunctive therapy to antibiotic treatment of acute respiratory infections.
PubMed:High plasma levels of MCP-1 and eotaxin provide evidence for an immunological basis of fibromyalgia.
PubMed:Simultaneous determination of phenylephrine hydrochloride, guaifenesin, and chlorpheniramine maleate in cough syrup by gradient liquid chromatography.
PubMed:Simultaneous determination of multi drug components Theophylline, Etofylline, Guaiphenesine and Ambroxol Hydrochloride by validated RP-HPLC method in liquid dosage form.
PubMed:New validated liquid chromatographic and chemometrics-assisted UV spectroscopic methods for the determination of two multicomponent cough mixtures in syrup.
PubMed:HPLC method for the simultaneous determination of atenolol and chlorthalidone in human breast milk.
PubMed:Over-the-counter medications for acute cough in children and adults in ambulatory settings.
PubMed:Cardiopulmonary effects of administration of a combination solution of xylazine, guaifenesin, and ketamine or inhaled isoflurane in mechanically ventilated calves.
PubMed:Enantiomer separation of the four diastereomers of guaiacyl glycerol from Hydnocarpus annamensis by capillary electrophoresis with HP-beta-CD as a chiral selector.
PubMed:Pholcodine exposure raises serum IgE in patients with previous anaphylaxis to neuromuscular blocking agents.
PubMed:Management and complications of anesthesia for transvenous electrical cardioversion of atrial fibrillation in horses: 62 cases (2002-2006).
PubMed:Experimental implementation of automatic 'cycle to cycle' control of a chiral simulated moving bed separation.
PubMed:Plasma colloid osmotic pressure and total protein in horses during colic surgery.
PubMed:Clinical inquiries. Is guaifenesin safe during pregnancy?
PubMed:New FDA guidance documents.
PubMed:Mucolytics, expectorants, and mucokinetic medications.
PubMed:Disassembly of lignin and chemical recovery in supercritical water and p-cresol mixture. Studies on lignin model compounds.
PubMed:Adjuvant therapies in the treatment of acute and chronic rhinosinusitis.
PubMed:Crystal growth formation in melt extrudates.
PubMed:"Crystal dex:" free-base dextromethorphan.
PubMed:Plasma colloid osmotic pressure and total protein trends in horses during anesthesia.
PubMed:Physicochemical properties of film-coated melt-extruded pellets.
PubMed:Evaluation of the effects of the sedation with azaperone/acepromazine and immobilization with guaiphenesin/thiopentone in mules.
PubMed:Effectiveness of amitriptyline versus cough suppressants in the treatment of chronic cough resulting from postviral vagal neuropathy.
PubMed:Diagnosis and treatment of cervical mucus abnormalities.
PubMed:Development and validation of chemometrics-assisted spectrophotometric and liquid chromatographic methods for the simultaneous determination of two multicomponent mixtures containing bronchodilator drugs.
PubMed:Non-enzymatic reduction of quinone methides during oxidative coupling of monolignols: implications for the origin of benzyl structures in lignins.
PubMed:Drug-induced urinary calculi.
PubMed:Simultaneous determination of dextromethorphan, dextrorphan, and guaifenesin in human plasma using semi-automated liquid/liquid extraction and gradient liquid chromatography tandem mass spectrometry.
PubMed:Wood stimulates the demethoxylation of [O14CH3]-labeled lignin model compounds by the white-rot fungi Phanerochaete chrysosporium and Phlebia radiata.
PubMed:Simultaneous, stability indicating, HPLC-DAD determination of guaifenesin and methyl and propyl-parabens in cough syrup.
PubMed:Effects of preoperative epidural administration of racemic ketamine for analgesia in sheep undergoing surgery.
PubMed:Beta-galactosidase catalyzed selective galactosylation of aromatic compounds.
PubMed:Cough suppressant and pharmacologic protussive therapy: ACCP evidence-based clinical practice guidelines.
PubMed:Effects of incorporated drugs on degradation of novel 2,2'-bis(2-oxazoline) linked poly(lactic acid) films.
PubMed:Application and validation of chemometrics-assisted spectrophotometry and liquid chromatography for the simultaneous determination of six-component pharmaceuticals.
PubMed:Spontaneous dissolution of a guaifenesin stone.
PubMed:Analysis of pharmaceutical preparations containing antihistamine drugs by micellar liquid chromatography.
PubMed:Simultaneous determination of some active ingredients in cough and cold preparations by gas chromatography, and method validation.
PubMed:Adolescent abuse of dextromethorphan.
PubMed:Use of over-the-counter medications during pregnancy.
PubMed:On-line solid phase extraction using the Prospekt-2 coupled with a liquid chromatography/tandem mass spectrometer for the determination of dextromethorphan, dextrorphan and guaifenesin in human plasma.
PubMed:Evaluation of xylazine and ketamine for total intravenous anesthesia in horses.
PubMed:Can Robitussin DM be used to treat cough during pregnancy?
PubMed:Voltammetric assay of Guaifenesin in pharmaceutical formulation.
PubMed:Influence of general anesthesia on pharmacokinetics of intravenous lidocaine infusion in horses.
PubMed:The effects of spontaneous and mechanical ventilation on central cardiovascular function and peripheral perfusion during isoflurane anaesthesia in horses.
PubMed:The cellulose/lignin assembly assessed by molecular modeling. Part 1: adsorption of a threo guaiacyl beta-O-4 dimer onto a Ibeta cellulose whisker.
PubMed:Therapeutic approaches to mucus hypersecretion.
PubMed:Effects of formulation variables and characterization of guaifenesin wax microspheres for controlled release.
PubMed:Pseudoephedrine and guaifenesin urolithiasis: widening the differential diagnosis of radiolucent calculi on abdominal radiograph.
PubMed:Simultaneous determination of ingredients in a cold medicine by cyclodextrin-modified microemulsion electrokinetic chromatography.
PubMed:In brief: Mucinex.
PubMed:Sensitive liquid chromatography-tandem mass spectrometry method for the simultaneous determination of paracetamol and guaifenesin in human plasma.
PubMed:Ephedrine- and guaifenesin-induced nephrolithiasis.
PubMed:Gender differences in psychogenic non-epileptic seizures.
PubMed:Alterations of nasal mucociliary clearance in association with HIV infection and the effect of guaifenesin therapy.
PubMed:Over-the-counter medications for acute cough in children and adults in ambulatory settings.
PubMed:High-performance liquid chromatographic analysis of dextromethorphan, guaifenesin and benzoate in a cough syrup for stability testing.
PubMed:Analysis of neutral drugs in human plasma by fluoride attachment in liquid chromatography/negative ion electrospray tandem mass spectrometry.
PubMed:The influence of guaifenesin and ketoprofen on the properties of hot-melt extruded polyethylene oxide films.
PubMed:Guaifenesin as a treatment for primary dysmenorrhea.
PubMed:Microencapsulation of a hydrophilic drug into a hydrophobic matrix using a salting-out procedure. I: Development and optimization of the process using factorial design.
PubMed:Determination of guaifenesin in human serum by capillary gas chromatography and electron capture detection.
PubMed:Microencapsulation of a hydrophilic drug into a hydrophobic matrix using a salting-out procedure. II. Effects of adsorbents on microsphere properties.
PubMed:Conformational study of a guaiacyl beta-O-4 lignin model compound by NMR. Examination of intramolecular hydrogen bonding interactions and conformational flexibility in solution.
PubMed:Cardiopulmonary effects of combined xylazine-guaiphenesin-ketamine infusion and extradural (inter-coccygeal lidocaine) anaesthesia in calves.
PubMed:Bilateral guaifenesin ureteral calculi.
PubMed:Physicochemical properties and mechanism of drug release from ethyl cellulose matrix tablets prepared by direct compression and hot-melt extrusion.
PubMed:Effect of guaifenesin on cough reflex sensitivity.
PubMed:Solubility of guaifenesin in the presence of common pharmaceutical additives.
PubMed:Polymerization of guaiacol and a phenolic beta-O-4-substructure by Trametes hirsuta laccase in the presence of ABTS.
PubMed:The cardiopulmonary effects of severe blood loss in anesthetized horses.
PubMed:[Research into simultaneous spectrophotometric determination of components in cough syrup by principal component regression method].
PubMed:Detection and characterization of a novel extracellular fungal enzyme that catalyzes the specific and hydrolytic cleavage of lignin guaiacylglycerol beta-aryl ether linkages.
PubMed:Resolution of ephedrine stones with dissolution therapy.
PubMed:[Comparative study of two antitussive drugs in the treatment of acute dry cough of infectious origin (prospective, randomized, single blind study)].
PubMed:Guaiacylglycerol-7'-O-methyl 8'-vanillic acid ether and related compounds from Boreava orientalis.
PubMed:Effects of treatment with oxytocin, xylazine butorphanol, guaifenesin, acepromazine, and detomidine on esophageal manometric pressure in conscious horses.
PubMed:Comparison of the cardiopulmonary effects of anesthesia maintained by continuous infusion of romifidine, guaifenesin, and ketamine with anesthesia maintained by inhalation of halothane in horses.
PubMed:Hidden respiratory allergies in voice users: treatment strategies.
PubMed:Guaifenesin enhances the analgesic potency of paracetamol in mice.
PubMed:Infusion of guaifenesin, ketamine, and medetomidine in combination with inhalation of sevoflurane versus inhalation of sevoflurane alone for anesthesia of horses.
PubMed:Clinical comparison of xylazine and medetomidine for premedication of horses.
PubMed:Drug release profiles from and degradation of a novel biodegradable polymer, 2,2-bis(2-oxazoline) linked poly(epsilon -caprolactone).
PubMed:Herbal antitussives.
PubMed:Degradation of and drug release from a novel 2,2-bis(2-oxazoline) linked poly(lactic acid) polymer.
PubMed:Physician specialty is associated with differences in the evaluation and management of acute bacterial rhinosinusitis.
PubMed:Over-the-counter medications for acute cough in children and adults in ambulatory settings.
PubMed:Comparison of thiopentone/guaifenesin, ketamine/guaifenesin and ketamine/midazolam for the induction of horses to be anaesthetised with isoflurane.
PubMed:Efficacy and safety of Ascoril in the management of cough--National Study Group report.
PubMed:Successful pregnancy despite advanced age and elevated serum follicle stimulating hormone levels--a case report.
PubMed:Effects of intravenous infusion of guaifenesin on electroencephalographic variables in pigs.
PubMed:Anesthetic, cardiorespiratory, and metabolic effects of four intravenous anesthetic regimens induced in horses immediately after maximal exercise.
PubMed:Simultaneous estimation of phenylpropanolamine HCl, guaiphenesin and diphenylpyraline HCl in syrups by LC.
PubMed:Managing secretions in dying patients.
PubMed:HPLC determination of guaifenesin with selected medications on underivatized silica with an aqueous-organic mobile phase.
PubMed:Efficacy and safety of Ascoril expectorant and other cough formula in the treatment of cough management in paediatric and adult patients--a randomised double-blind comparative trial.
PubMed:Comparison of four drug combinations for total intravenous anesthesia of horses undergoing surgical removal of an abdominal testis.
PubMed:Combination of continuous intravenous infusion using a mixture of guaifenesin-ketamine-medetomidine and sevoflurane anesthesia in horses.
PubMed:The recovery of horses from inhalant anesthesia: a comparison of halothane and isoflurane.
PubMed:Parents on the web: risks for quality management of cough in children.
PubMed:Guaifenesin- and ephedrine-induced stones.
PubMed:Effects of drugs on mucus clearance.
PubMed:An in vitro comparison of the mucoactive properties of guaifenesin, iodinated glycerol, surfactant, and albuterol.
PubMed:Abuse of guaifenesin-containing medications generates an excess of a carboxylate salt of beta-(2-methoxyphenoxy)-lactic acid, a guaifenesin metabolite, and results in urolithiasis.
PubMed:Acute intoxication with guaifenesin, diphenhydramine, and chlorpheniramine.
PubMed:Drug release from diffusion pellets coated with the aqueous ethyl cellulose dispersion Aquacoat ECD-30 and 20% dibutyl sebacate as plasticizer: partition mechanism and pore diffusion.
PubMed:Anesthesia case of the month. Laryngeal stridor in a horse caused by an epiglottic cyst.
PubMed:Bioavailability of dextromethorphan (as dextrorphan) from sustained release formulations in the presence of guaifenesin in human volunteers.
PubMed:Comparison of two techniques for total intravenous anesthesia in horses.
PubMed:Cardiovascular effects of surgical castration during anaesthesia maintained with halothane or infusion of detomidine, ketamine and guaifenesin in ponies.
PubMed:Comparison of detomidine/ketamine and guaiphenesin/thiopentone for induction of anaesthesia in horses maintained with halothane.
PubMed:Coupled achiral/chiral column techniques in subcritical fluid chromatography for the separation of chiral and nonchiral compounds.
PubMed:Simulated moving bed chromatographic resolution of a chiral antitussive.
PubMed:Maternal illness, including fever and medication use as risk factors for neural tube defects.
PubMed:Pharmacokinetics and cardiopulmonary effects of guaifenesin in donkeys.
PubMed:Extralabel use of tranquilizers and general anesthetics.
PubMed:Endocrine changes in cerebrospinal fluid, pituitary effluent, and peripheral plasma of anesthetized ponies.
PubMed:A survey of adolescents' knowledge regarding toxicity of over-the-counter medications.
PubMed:Management of sinusitis in adult cystic fibrosis.
PubMed:Evaluation of antitussive agents in man.
PubMed:Hyperkalemic periodic paralysis episode during halothane anesthesia in a horse.
PubMed:Evaluation of five common induction protocols by comparison of hemodynamic responses to surgical manipulation in halothane-anesthetized horses.
PubMed:Simultaneous assay of phenylpropanolamine hydrochloride, caffeine, paracetamol, glycerylguaiacolate and chlorpheniramine maleate in Silabat tablet using HPLC with diode array detection.
PubMed:The haemodynamic effects of milrinone HCl in halothane anaesthetised horses.
PubMed:Bioavailability of pseudoephedrine from controlled release formulations in the presence of guaifenesin in human volunteers.
PubMed:Total intravenous anaesthesia in ponies using detomidine, ketamine and guaiphenesin: pharmacokinetics, cardiopulmonary and endocrine effects.
PubMed:Simultaneous determination of dextrorphan and guaifenesin in human plasma by liquid chromatography with fluorescence detection.
PubMed:Blood gas values during intermittent positive pressure ventilation and spontaneous ventilation in 160 anesthetized horses positioned in lateral or dorsal recumbency.
PubMed:Confidential enquiry of perioperative equine fatalities (CEPEF-1): preliminary results.
PubMed:Effects of guaifenesin on nasal mucociliary clearance and ciliary beat frequency in healthy volunteers.
PubMed:Isoflurane anesthesia in a rhinoceros.
PubMed:Staging of chronic hyperplastic rhinosinusitis: treatment strategies.
PubMed:Hemodynamic responses of horses to anesthesia and surgery, before and after administration of a low dose of endotoxin.
PubMed:Sevoflurane and oxygen anaesthesia following administration of atropine-xylazine-guaifenesin-thiopental in spontaneously breathing horses.
PubMed:Dependence of phonatory effort on hydration level.
PubMed:Use of in vitro and in vivo data in the design, development, and quality control of sustained-release decongestant dosage forms.
PubMed:Sevoflurane anesthesia following administration of atropine-guaifenesin-thiopental in spontaneous-breathing adult cattle.
PubMed:Determination of guaiphenesin in anti-tussive pharmaceutical preparations containing dextromethorphan by first- and second-derivative ultraviolet spectrophotometry.
PubMed:Intravenous anaesthesia in horses by guaiphenesin-ketamine-detomidine infusion: some effects.
PubMed:Methocarbamol degradation in aqueous solution.
PubMed:Evaluation of pulse oximetry in horses surgically treated for colic.
PubMed:A case report on the use of guaifenesin-ketamine-xylazine anesthesia for equine dystocia.
PubMed:Effects of atropine on the arrhythmogenic dose of dobutamine in xylazine-thiamylal-halothane-anesthetized horses.
PubMed:Effects of anesthesia induced and maintained by continuous intravenous administration of guaifenesin, ketamine, and xylazine in spontaneously breathing sheep.
PubMed:Urticarial response during anesthesia in a horse.
PubMed:Efficacy of cough suppressants.
PubMed:Desquamative interstitial pneumonia: a case presentation.
PubMed:Hemorrhagic myelomalacia following general anesthesia in a horse.
PubMed:Determination of guaifenesin in human plasma by liquid chromatography in the presence of pseudoephedrine.
PubMed:Effectiveness of cough syrups.
PubMed:Immobilization and anesthesia of two hand-reared zebras.
PubMed:Neuromuscular blockade by use of atracurium in anesthetized llamas.
PubMed:Comparison of two surgical methods for treatment of crib-biting in horses.
PubMed:Clinical evaluation of an infusion of xylazine, guaifenesin and ketamine for maintenance of anaesthesia in horses.
PubMed:Clinical trial examining effectiveness of three cough syrups.
PubMed:Microencapsulation of drugs with aqueous colloidal polymer dispersions.
PubMed:Lignin peroxidase L3 from Phlebia radiata. Pre-steady-state and steady-state studies with veratryl alcohol and a non-phenolic lignin model compound 1-(3,4-dimethoxyphenyl)-2-(2-methoxyphenoxy)propane-1,3-diol.
PubMed:Effect of hypercapnia on the arrhythmogenic dose of epinephrine in horses anesthetized with guaifenesin, thiamylal sodium, and halothane.
PubMed:Effect of xylazine on the arrhythmogenic dose of epinephrine in thiamylal/halothane-anesthetized horses.
PubMed:Effects of 5% and 10% guaifenesin infusion on equine vascular endothelium.
PubMed:The role of guaifenesin in the treatment of sinonasal disease in patients infected with the human immunodeficiency virus (HIV).
PubMed:Effects of general anesthesia on myoelectric activity of the intestine in horses.
PubMed:A combination of methotrimeprazine, midazolam and guaiphenesin, with and without ketamine, in an anaesthetic procedure for horses.
PubMed:Hemodynamic function during neurectomy in halothane-anesthetized horses with or without constant dose detomidine infusion.
PubMed:[Continuous intravenous anesthesia in dogs using a combination of xylazine, ketamine and guaifenesin].
PubMed:Psychosis with Vicks Formula 44-D abuse.
PubMed:Anesthetic management of an incisional dehiscence in recovery following exploratory laparotomy in a horse.
PubMed:The pharmacology and pharmacokinetics of high-dose methocarbamol in horses.
PubMed:Simultaneous determination of theophylline and guaiphenesin by third-derivative ultraviolet spectrophotometry and high-performance liquid chromatography.
PubMed:Surgical treatment of uterine torsion in a llama (Lama glama).
PubMed:Electromyography of some respiratory muscles in the horse.
PubMed:Effects of an infusion of dopamine on the cardiopulmonary effects of Escherichia coli endotoxin in anaesthetised horses.
PubMed:Long term anesthesia using a continuous infusion of guaifenesin, ketamine and xylazine in cats.
PubMed:Prolongation of anesthesia with xylazine, ketamine, and guaifenesin in horses: 64 cases (1986-1989).
PubMed:Intravenous anesthesia.
PubMed:Hemodynamic effects of carbon dioxide during intermittent positive-pressure ventilation in horses.
PubMed:[Combination anesthesia in sheep with ketamine-(fentanyl)-guaifenesin (My 301)-laughing gas-halothane].
PubMed:A comparison of xylazine-diazepam-ketamine and xylazine-guaifenesin-ketamine in equine anesthesia.
PubMed:Identification and differentiation of barbiturates, other sedative-hypnotics and their metabolites in urine integrated in a general screening procedure using computerized gas chromatography-mass spectrometry.
PubMed:Degradation of labelled lignins and veratrylglycerol-beta-guaiacyl ether by Acinetobacter sp.
PubMed:Metabolic and hormonal changes associated with arthroscopic surgery in the horse.
PubMed:Effect of Mn(II) on reactions catalyzed by lignin peroxidase from Phanerochaete chrysosporium.
PubMed:Cardiopulmonary effects of butorphanol tartrate intravenously administered for placement of duodenal cannulae in isoflurane-anesthetized yearling steers.
PubMed:Jugular thrombophlebitis resulting from an anaesthetic induction technique in the horse.
PubMed:Cardiopulmonary effects of positive end-expiratory pressure in anesthetized, mechanically ventilated ponies.
PubMed:Organic affective psychosis associated with the routine use of non-prescription cold preparations.
PubMed:Hemolytic potential of guaifenesin in cattle.
PubMed:The influence of furosemide on plasma elimination and urinary excretion of drugs in standardbred horses.
PubMed:[Anesthesia of horses with xylazine and ketamine. 2. Anesthesia in adult horses].
PubMed:Influence of preinduction methoxamine, lactated Ringer solution, or hypertonic saline solution infusion or postinduction dobutamine infusion on anesthetic-induced hypotension in horses.
PubMed:Cardiovascular effects recorded in horses during anaesthesia after treatment with trichlorfon.
PubMed:Anesthesia in the llama.
PubMed:High frequency jet ventilation in horses: an experimental study.
PubMed:Postanesthetic compartmental syndrome in a horse.
PubMed:The inflight use of three pharmacological preparations: Humibid, Nicorette, and Seldane.
PubMed:A retrospective survey of anaesthesia in horses with colic.
PubMed:[Densitometric determination of propyphenazone, paracetamol, guaiacol glycerol ether, caffeine and acetylsalicylic acid in analgesic-antipyretic preparations with thin-layer chromatography].
PubMed:Llama anesthetic programs.
PubMed:Tourniquet-induced hypertension in a horse.
PubMed:Haemodynamic, metabolic and physical responses to a neuroleptanalgesic-glyceryl guaiacolate combination in the horse.
PubMed:Measurement of methsuximide and N-desmethylmethsuximide using solid-phase extraction and wide-bore capillary gas chromatography.
PubMed:High-pressure liquid chromatographic assay of dextromethorphan hydrobromide, guaifenesin, and sodium benzoate in an expectorant syrup.
PubMed:Comparison of cardiopulmonary effects of isoflurane and halothane after atropine-guaifenesin-thiamylal anesthesia for rumenotomy in steers.
PubMed:The effect of guaiphenesin on absorption and bioavailability of paracetamol from composite analgesic preparations.
PubMed:Rabbit anaesthetic deaths.
PubMed:Hemodynamic and respiratory responses in halothane-anesthetized horses exposed to positive end-expiratory pressure alone and with dobutamine.
PubMed:Hematologic and serum biochemical alterations associated with multiple halothane anesthesia exposures and minor surgical trauma in horses.
PubMed:Retrospective assessment of dobutamine therapy for hypotension in anesthetized horses.
PubMed:Guaifenesin alone or in combination with ketamine or sodium pentobarbital as an anesthetic in rabbits.
PubMed:A comparative randomized double-blind clinical trial of hexapneumine and clistine as antitussive agents.
PubMed:[Significance of the interaction between analgesic-antipyretics and ethanol in forensic medicine investigations].
PubMed:[The modification of central venous pressure in the horse].
PubMed:[The behavior of specific parameters of acid-base balance, heart rate and depth of anesthesia during chloral hydrate anesthesia and chloral hydrate-My 301 anesthesia in horses].
PubMed:Simultaneous capillary gas chromatographic determination of guaifenesin, dextromethorphan and diphenhydramine in cough-cold syrup.
PubMed:[The clinical pharmacology of glycerol guaiacolate ether in the horse--a review].
PubMed:Cardiopulmonary effects of continuous intravenous infusion of guaifenesin, ketamine, and xylazine in ponies.
PubMed:Diagnosis and treatment of the cervical factor. I. Improvement with a short-course treatment of high-dose estrogen.
PubMed:Cardiopulmonary responses of swine to intravenous infusion of guaifenesin, ketamine, and xylazine.
PubMed:Biomimetic oxidation of lignin model compounds by simple inorganic complexes.
PubMed:Hypertension in bulls and steers anesthetized with guaifenesin-thiobarbiturate-halothane combination.
PubMed:Dobutamine-induced augmentation of cardiac output does not enhance respiratory gas exchange in anesthetized recumbent healthy horses.
PubMed:Deoxyglucose-autoradiography of the hypothalamus after food deprivation in the mouse.
PubMed:The effect on vigilance of an analgesic combination (Ataralgin) and its components, guaiphenesine and caffeine.
PubMed:[Changes in the cough reflex after the administration of guaifenesin].
PubMed:Anaerobic degradation of veratrylglycerol-beta-guaiacyl ether and guaiacoxyacetic acid by mixed rumen bacteria.
PubMed:Cardiopulmonary effects of an intravenous infusion of guaifenesin, ketamine, and xylazine in dogs.
PubMed:A new bacterial dehydrogenase oxidizing the lignin model compound guaiacylglycerol beta-O-4-guaiacyl ether.
PubMed:Guaiphenesin and iodide.
PubMed:Short duration general anaesthesia in the horse using guaiacol glycerine ether and thiopentone sodium.
PubMed:Bioavailability of dyphylline and dyphylline-guaifenesin tablets in humans.
PubMed:Use of guaiacol glycerine ether in clinical anaesthesia in the horse.
PubMed:Catabolism of arylglycerol-beta-aryl ethers lignin model compounds by Pseudomonas cepacia 122.
PubMed:On the non-specific antiinflammatory effects of other-than-antirheumatic drugs. Psychotropic drugs, inflammation and antiinflammatory drugs.
PubMed:Determination of the structure of a synthetic impurity in guaifenesin: modification of a high-performance liquid chromatographic method for phenylephrine hydrochloride, phenylpropanolamine hydrochloride, guaifenesin, and sodium benzoate in dosage forms.
PubMed:Selection of mixed ion-pair modifiers for high-performance liquid chromatographic mobile phases.
PubMed:Pharmacologic and pharmacokinetic properties of methocarbamol in the horse.
PubMed:Anesthesia for cesarean section in large animals.
PubMed:[Simultaneous determination of nikethamide and guaiafenesin by derivative UV spectrophotometry].
PubMed:Isolation, partial identification and quantitative determination of four guaiphenesin glucuronides in plasma and urine of the horse by high-performance liquid chromatography.
PubMed:Observations on the use of glyceryl guaiacolate as an adjunct to general anaesthesia in horses.
PubMed:[Anesthesia in the horse].
PubMed:Field anaesthesia in the horse.
PubMed:Antitussive effect of guaifenesin.
PubMed:Physiological and biochemical effects of glyceryl guaiacolate-thiopentone sodium anaesthesia in buffalo calves.
PubMed:Practical equine injectable anesthesia.
PubMed:Simultaneous determination of acetaminophen, guaifenesin, pseudoephedrine, pholcodine, and paraben preservatives in cough mixture by high-performance liquid chromatography.
PubMed:Simultaneous stability-indicating determination of phenylephrine hydrochloride, phenylpropanolamine hydrochloride, and guaifenesin in dosage forms by reversed-phase paired-ion high-performance liquid chromatography.
PubMed:[Sobrerol as expectorant in patients with stable chronic respiratory tract infections. A controlled study].
PubMed:Antitussive effect of guaifenesin in young adults with natural colds. Objective and subjective assessment.
PubMed:Effect of postural changes on certain circulatory and respiratory values in the horse.
PubMed:Anesthetic management of the patient with acute abdominal disease.
PubMed:Improvement of cervical factor with guaifenesin.
PubMed:Efficacy of phenylephrine-phenylpropanolamine in the treatment of rhinitis.
PubMed:The effect of acute guaifenesin administration on serum uric acid.
PubMed:[Secretagogue action of glyceryl guaiacolate in tracheal submucosal glands (author's transl)].
PubMed:[Combined treatment of idiopathic dysmenorrhoea by acetylsalicylic acid and guaiphenezine (author's transl)].
PubMed:Determination of guaiphenesin and its metabolite, beta-(2-methoxyphenoxy)-lactic acid, in plasma by high-performance liquid chromatography.
PubMed:[Clinical evaluation of the activity of 2 preparations with similar action in bronchopneumopathies in the aged].
PubMed:[Immobilization of horses with drugs].
PubMed:Comparative absorption of theophylline from theophylline-guaifenesin tablets and liquid and from a reference theophylline liquid.
PubMed:Evaluation of glyceryl guaiacolate as a muscle relaxant in buffalo calves.
PubMed:Guaifenesin: cardiopulmonary effects and plasma concentrations in horses.
PubMed:The determination of bifunctional compounds. IX. A selective reaction for the determination of guaifenesin in plasma by gas chromatography.
PubMed:Chemical restraint in the horse.
PubMed:[Investigations of guaifenesine metabolism with gas chromatography-mass spectrometry].
PubMed:[The detection of guaiacol glyceryl ether, a content of many sedatives and hypnotics in the Federal Republic of Germany].
PubMed:Effect of glyceryl guaiacolate in animal models of inflammation and pain.
PubMed:Continuous determination of tracheobronchial secretory activity in dogs.
PubMed:Evaluation of concentrated solutions of guaifenesin for equine anesthesia.
PubMed:[Chronic spastic bronchitis, Broncho-euphylline in a double-blind study].
PubMed:Simultaneous high-pressure liquid chromatographic determination of acetaminophen, guaifenesin, and dextromethorphan hydrobromide in cough syrup.
PubMed:[Guaiacolglycerylether in horses and ponies].
PubMed:Postural effects on lung volumes and asynchronous ventilation in anesthetized horses.
PubMed:[Treatment of acute attacks of chronic bronchitis].
PubMed:[General practice-field trials of Linctifed with 17871 patients with inflammatory diseases of the respiratory tract].
PubMed:Determination of dextromethorphan in serum by gas chromatography.
PubMed:The effect of tranquillizers on the rhythmic function order of the autonomous nervous system.
PubMed:[Guaiacol glyceryl ether study in horses and ponies. 1. The pharmacokinetics after a single i.v. injection].
PubMed:Rapid, stability-indicating, high-pressure liquid chromatographic determination of theophylline, guaifenesin, and benzoic acid in liquid and solid pharmaceutical dosage forms.
PubMed:Evaluation of guaiacol derivatives in pharmaceutical preparations by spectrofluorimetric techniques.
PubMed:Impairment of hemostasis in patients with severe hemophilia. Failure of diphenhydramine, chlorpromazine, and guaifenesin.
PubMed:Glyceryl guaiacolate in equine anaesthesia.
PubMed:An investigation of the action and haemolytic effect of glyceryl guaiacolate in the horse.
PubMed:Evaluation of xylazine, guaifenesin, and ketamine hydrochloride for restraint in horses.
PubMed:Liquid chromatographic analysis of pharmaceutical syrups using pre-columns and salt-adsorption on amberlite XAD-2.
PubMed:[Does guaiphenesin lack expectorant qualities?].
PubMed:Controlled assessment of oral bronchodilators for asthmatic children.
PubMed:Some applications of bonded-phase high-performance liquid chromatography to the analysis of pharmaceutical formulations.
PubMed:Cough. A comprehensive review.
PubMed:[Broncho-Binotal-juice in unspecific infections of the respiratory tract in old age].
PubMed:The effects of "anti-platelet" drugs on bleeding time and platelet aggregation in normal human subjects.
PubMed:Quantitative determinations of codeine phosphate, guaifenesin, pheniramine maleate, phenylpropanolamine hydrochloride, and pyrilamine maleate in an expectorant by high-pressure liquid chromatography.
PubMed:Quantitative determination of four antihistamines in combination by high-pressure liquid chromatography.
PubMed:[Symptomatic treatment of acute inflammation of the upper respiratory airways in pediatrics].
PubMed:[Drug combination with antitussive activity. Clinical trial].
PubMed:Thoracic duct lymph in conscious dogs at rest and during changes of physical activity.
PubMed:Drugs used in the treatment of asthma.
PubMed:A trial of Lotussin and linctus diphenhydramine in patients wth an irritant cough.
PubMed:[Double-blind long-term study on a combination of tetracycline, theophylline, doxylamine succinate, etafedrine, phenylephedrine and guaifenesine in chronic bronchitis (author's transl)].
PubMed:Guaifenesin effects on the guaiac test for occult blood.
PubMed:The effects of four commonly used drugs on platelet function.
PubMed:[Kinetics of the ampicillin release in a combination preparation].
PubMed:[Clinical study on a antitussive syrup based on noscapinium chloride].
PubMed:Emergency surgery on a gored horse.
PubMed:Diphasic action of the aliphatic amide, HOE 17879, on hepatic microsomal drug metabolizing enzymes in the mouse.
PubMed:Clinical evaluation of terbutaline and glyceryl guaiacolate in chronic obstructive lung disease.
PubMed:[Therapy of the chronic bronchitic syndrome using Linctifed].
PubMed:Glyceryl guaiacolate in anesthesea.
PubMed:Effect of bromhexine and guaiphenesine on clinical state, ventilatory capacity and sputum viscosity in chronic asthma.
PubMed:Letter: Negative guaiac test after glyceryl guaiacolate.
PubMed:Chronic obstructive pulmonary disease.
PubMed:[Early diagnosis and early treatment of chronic bronchial diseases for the prevention of early invalidity].
PubMed:[Defence capacities of the respiratory tract].
PubMed:Anesthesia of bulls undergoing surgical manipulation of the vas deferentia.
PubMed:[The treatment of the pseudocroup syndrome (author's transl)].
PubMed:Use of glyceryl guaiacolate ether in treating strychnine poisoning in the dog.
PubMed:The use of Duopect as expectorant--antitussive agent.
PubMed:[Clinical investigation of a combination preparation of ampicillin, theophylline, papaverine-HCl and guaiacolglyceryl ether. 2. In form of syrup].
PubMed:[Clinical investigation of a combination preparation of ampicillin, theophylline, papaverine-HCl and guaiacolglyceryl ether. 1. In form of tablets].
PubMed:[Therapy of bronchial asthma].
PubMed:The induction of general anaesthesia in the horse with glyceryl guaiacolate. Comparison when used alone and with sodium thiamylal (Surital).
PubMed:Volumetric determination of glyceryl guaiacolate in syrups.
PubMed:Anesthetic complications.
PubMed:Collaborative study of the determination of glyceryl guaiacolate in pharmaceutical dosage by conventional direct current polarography.
PubMed:Nasal congestion as a side effect of cromolyn sodium.
PubMed:Uricosuric effect of glyceryl guaiacolate.
PubMed:"Combination" anti-asthmatic therapy: recent developments.
PubMed:[Attempt to test a new antitussive agent].
PubMed:Action of strychnine and central depressants on the cerebello-rubral system.
PubMed:Changes in the fibre system and viscosity of the sputum of bronchitis during treatment with bromhexine and guaiphenesin (guaiacol glyceryl ether).
PubMed:[Therapeutic activity of an association of a mucolytic drug and a bronchodilator agent in the treatment of respiratory inflammations].
PubMed:A preliminary study of the effect of guaiphenesin on mucociliary clearance from the human lung.
PubMed:The effect of the combination of phenobarbitone, ephedrine, aminophylline and glyceryl guaiacolate on asthma and chronic bronchitis.
PubMed:Letter: Expectorant effect of glyceryl guiacolate.
PubMed:Colorimetric determination of glyceryl guaiacolate.
PubMed:[Multi-layer therapy of broncho-pulmonary infections in general practice using Sagittacin].
PubMed:[Possibility of effective treatment of bronchopulmonary diseases, including the bronchitic syndrome, with Broncho-Binotal].
PubMed:Automated, simultaneous determination of dextromethorphan hydrobromide, glyceryl guaiacolate, and phenylpropanolamine hydrochloride in cough syrups.
PubMed:The pharmacological action and O-demethylation of glyceryl guaiacolate ether in male and female rats.
PubMed:[Round table. Relevant controls and usefulness of treatments modifying bronchial secretions (author's transl)].
PubMed:Anaesthesia in horses.
PubMed:[Noscapine and guaiacol as cough remedies].
PubMed:[Therapy of the chronic bronchitis syndrome].
PubMed:The clinical significance of hypouricemia.
PubMed:Anesthetic management and recovery of large orthopedic patients.
PubMed:Glyceryl guaiacolate: some effects and indications in horses.
PubMed:Drug treatment in bronchial asthma.
PubMed:Clinical trial with terbutaline and guajacol.
PubMed:The expectorant effect of glyceryl guaiacolate in patients with chronic bronchitis. A controlled in vitro and in vivo study.
PubMed:[Treatment of the bronchitic syndrome associated with bacterial infection].
PubMed:Potentiating effects of chlorpromazine on the paralysis and toxicity induced by guaiacal glyceryl ether in rats.
PubMed:-(2-Methoxyphenoxy)lactic acid, the major urinary metabolite of glyceryl guaiacolate in man.
PubMed:[Cardiovascular effects of guaiacol glycerol ether mononicotinate].
PubMed:Analysis of urinary 5-hydroxyindoleacetic acid by thin layer chromatography: elimination of interference by glyceryl guaiacolate.
PubMed:Biopharmaceutical studies on guaiacol glyceryl ether and related compounds. V.
PubMed:Effect of glyceryl guaiacolate-thiamylal sodium solution on respiratory function and various hematologic factors of the horse.
PubMed:[Cough as a main symptom and its treatment].
PubMed:Effects of glyceryl guaiacolate on certain serum, plasma and cellular parameters in ponies.
PubMed:[Clinical experimentation with a new enzyme-antibiotic-expectorant combination in the treatment of acute and chronic laryngeo-tracheo-bronchitis].
PubMed:[Treatment of chronic bronchial diseases using a new sulfonamide compound preparation].
PubMed:The influence of glyceryl guaiacolate ether on the osmotic fragility of erythrocytes in rats.
PubMed:[Guaiacol glyceryl ether].
PubMed:[Sources of error of practical significance in the determination of urinary 5-HIAA].
PubMed:Stimulatory effects of phenobarbital pretreatment on the metabolism of glyceryl guaiacolate ether.
PubMed:Glyceryl guaiacolate as an adjunct to equine anesthesia.
PubMed:[Trial of an injectable antispasmodic agent, Dilavacol, during delivery (apropos of 50 cases)].
PubMed:[Action of guaiacol glycerol ether on isolated skeletal muscle].
PubMed:[Treatment of the acute broncho-pulmonary infections and superinfections by an antibiotic preparation with symptomatic aim].
PubMed:Acid dye method for the analysis of codeine phosphate.
PubMed:[Animal experiment on the absorption, distribution and elimination of C 14 - and H 3 -labelled guaiacol-glyceryl-ether].
PubMed:Formation and biological degradation of lignins.
PubMed:[Effect of a-substituted glycerin ether on the central nervous system].
PubMed:Evaluation of thiamylal sodium, succinylcholine, and glyceryl guaiacolate prior to inhalation anesthesia in horses.
PubMed:Observations on the use of glyceryl guaiacolate in the horse.
PubMed:GLC determination of guaiacol glyceryl ether in blood.
PubMed:[Study of the action of the association of glyceric ether of guaiacol and camylofine on the dilatation of the cervix during the labor].
PubMed:[Lethal allergic and toxic reaction following common drug administration].
PubMed:Effects of monoamine oxidase inhibitors, glyceryl gualacolate, and ethanol on experimental arterial thrombosis.
PubMed:[Resorption, distribution and excretion of guaiacol glyceryl ether and its effect on the physiological parameters].
PubMed:Effect of training on the analgesics action of morphine.
PubMed:[Colorimetric determination of guaiaphenesine in pharmaceutical preparations].
PubMed:Simultaneous determination of nonderivated phenylpropanolamine, glyceryl guaiacolate, chlorpheniramine, and dextromethorphan by gas chromatography.
PubMed:Bronchopulmonary effects of paraquat and expectorants.
PubMed:Pharmacokinetics and metabolism of glyceryl guaiacolate in ponies.
PubMed:Observations on the cardiovascular and respiratory effects of guaiacol glycerol ether in conscious and anaesthetized dogs.
PubMed:False-positive tests for urinary 5-hydroxyindoleacetic acid. Error in laboratory determinations caused by glyceryl guaiacolate.
PubMed:Gas chromatographic determination of glycerol guaiacolate in pharmaceutical preparations.
PubMed:The influence of guaiacol glycerol ether on cardiovascular and respiratory function in the horse.
PubMed:[Effect of guaiacol glyceryl ether on the formation of conditioned reflexes, "EEG" arousal and spontaneous bioelectric activity of brain in rats].
PubMed:A review of studies on the pharmacology of the expectorants and inhalants.
PubMed:[Long term and permanent treatment of spastic bronchial diseases].
PubMed:Biopharmaceutical studies on guiacol glycerol ether and related compounds. 3. Metabolites of guaiacol glycerol ether and its mononicotinate. 1.
PubMed:[Effect of neurolax on spasticity in the light of clinical observations].
PubMed:[Therapy of respiratory tract diseases. Experiences with a Rondomycin combination preparation].
PubMed:[Long-term treatment of the bronchitis syndrome].
PubMed:Biopharmaceutical studies on guaiacol glycerol ether and related compounds. II. Hypocholesteremic action. 1.
PubMed:[On the treatment of respiratory tract infections with Pulmo-Verlamycol].
PubMed:[Combination of chloramphenicol succinate of pyrrolidine methyl-tetracycline, guaiacol glyceryl ether and beta-hydroxypropyl-theophylline in the therapy of diseases of the respiratory tract in aged patients].
PubMed:[Glycerine-guaiacol ether in ophthalmic surgery].
PubMed:The effect of glyceryl guaiacolate on platelet function and other coagulation factors in vivo.
PubMed:Enzymic degradation of lignin. V. The effect of NADH on the enzymic cleavage of arylalkylether bond in veratrylglycerol-beta-guaiacylether as lignin model compound.
PubMed:[Therapy of spastic syndromes].
PubMed:[Psychopharmaca in modern medicine].
PubMed:Clinical use of glyceryl guaiacolate in the horse.
PubMed:A controlled evaluation of oral theophylline in asthmatic children.
PubMed:[Clinical study of a balsam-enzyme-tetracycline combination in inflammatory disorders of the respiratory and female genital system].
PubMed:[Clinical study of a combination of a balsam, an enzyme and tetracycline for inflammatory conditions of the respiratory tract and the female genitalia].
PubMed:Quantitative determination of methapyrilene hydrochloride and glyceryl guaiacolate in cough syrups.
PubMed:Quantitative determination of some single and multiple component drugs by gas-liquid chromatography.
PubMed:The role of glyceryl guaiacolate in a balanced equine anesthetic.
PubMed:[Experience with the drug neuroton in the treatment of cerebral palsy].
PubMed:The comparative effects of glyceryl guaiacolate and adenosine on the inhibition of ADP-induced platelet aggregation.
PubMed:Double-blind evaluation of an anti-asthmatic agent.
PubMed:Studies on absorption and excretion of drugs. XXIX. Biopharmaceutical studies on guaiacol glycerol ether and related compounds. I. Blood level of guaiacol glycerol ether in rabbit and its binding with serum proteins.
PubMed:[Pharmacologic studies of the strychnine tremor in infantile mice].
PubMed:Effect of an anti-asthmatic compound on blood pressure of hypertensive asthmatic patients.
PubMed:Determination of phenylephrine in combinations with other drugs.
PubMed:[Intubation anesthesia with fluothane in ambulatory practice in horses with a specially developed pendulum system].
PubMed:The pharmacological basis of the expectorant action of glyceryl guaiacolate.
PubMed:Effect of guaiphenesin on labour.
PubMed:[Muscle relaxants. 4].
PubMed:[New drugs. Premenstrin. (Tablets)].
PubMed:[Use of the myorelaxant GGG-Forte in surgery].
PubMed:[The treatment of unspecific coughs during a spá cure in a health resort for rheumatics].
PubMed:Muscle relaxant properties of glyceryl guaiacolate.
PubMed:Clinical evaluation of an antiasthmatic compound. Correlation of absorption with blood levels of theophylline.
PubMed:[Etiology and therapy of tics in childhood].
PubMed:Reduction of platelet adhesiveness and prolongation of coagulation-time of activated plasma by glyceryl guaiacolate.
PubMed:[Therapeutic efficacy and tolerance of a new pharmacologic combination in the treatment of pneumopathic forms].
PubMed:[Studies on the pharmacological effect of aromatic glycide ethers].
PubMed:Chronic respiratory disease in geriatric patients: symptomatic therapy.
PubMed:[Alpha-substituted glyceryl ethers in modern anesthesia].
PubMed:[Postoperative urinary retention. Clinical research on the action of muscle relaxants].
PubMed:[The adequacy of guaiacol glyceryl ether for drug induced relaxation of horses and cattle as well as for prolonged relaxation in tetanus therapy].
PubMed:[The suitability of guaiacol glyceryl ethers for drug elimination in horses and cattle and for the prolonged relaxation in tetanus therapy].
PubMed:[Effectiveness of guaiacol glyceryl ether in the drug-sedation of horses and cattle and in prolonged relaxation in the treatment of tetanus].
PubMed:THE INFLUENCE OF VARIOUS SUBSTANCES ON METABOLISM AND RESISTANCE OF TRAUMATIZED RATS.
PubMed:[TREATMENT OF RESPIRATORY INFECTIONS IN INFANTS AND CHILDREN].
PubMed:GUAIACOL GLYCERYL ETHER THEOPHYLLINATE. ITS VALUE FOR RELIEF OF BRONCHIAL ASTHMA AND RELATED BRONCHOSPASTIC CONDITIONS.
PubMed:[SIGNS AND SYMPTOMS DURING THE INTRAVENOUS ADMINISTRATION OF THE MUSCLE RELAXANT, REORGANIN, WITHOUT PREMEDICATION].
PubMed:[SPONDYLON IN BATH REACTIONS IN PATIENTS WITH SPINAL DISEASES].
PubMed:CLINICAL STUDY WITH OXTRIPHYLLINE-GLYCERYL GUAIACOLATE TABLETS IN CHRONIC PULMONARY DISEASE: A DOUBLE-BLIND CROSSOVER STUDY.
PubMed:[CONTRIBUTIONS TO MODERN VIEWS ON AND TREATMENT OF STUTTERING].
PubMed:[SAFE ANESTHESIA IN INTRAOCULAR OPERATIONS (COMBINATION OF POTENTIATED ANESTHESIA WITH MY 301)].
PubMed:OXTRIPHYLLINE-GLYCERYL GUAIACOLATE ELIXIR AS EFFECTIVE THERAPY FOR CHRONIC BRONCHITIS AND ASTHMA.
PubMed:TREATMENT OF BRONCHIAL AND PULMONARY PARENCHYMAL DISORDERS.
PubMed:CLINICAL EVALUATION OF A BRONCHODILATOR DRUG COMBINATION IN CHILDREN WITH CHRONIC BRONCHIAL ASTHMA.
PubMed:[ON THE EFFECT OF O-METHOXYPHENYLGLYCEROL ETHER (MY 301) ON THE EXCITABILITY OF THE GASTROCNEMIUS MUSCLE IN RANA ESCULENTA].
PubMed:THEOPHYLLINE-GLYCERYL GUAIACOLATE CAPSULES (QUIBRON). CLINICAL RESULTS IN BRONCHIAL ASTHMA.
PubMed:A DOUBLE BLIND CLINICAL EVALUATION OF GLYCERYL GUAIACOLATE.
PubMed:[CONTRIBUTION TO THE USE OF INTRAVENOUS CHLOROPROMAZINE IN TETANUS].
PubMed:[CRITICAL EVALUATION OF KYMOINSUFFLATION AS A METHOD OF DETERMINING THE EFFECT OF DRUGS ON UTERO-TUBAL MUSCULAR ACTIVITY].
PubMed:[COMPLICATIONS OF ANESTHESIA OVER A 10-YEAR PERIOD].
PubMed:CLINICAL EFFECTIVENESS OF OXTRIPHYLLINE-GLYCERYL GUAIACOLATE COMBINATION IN CHRONIC BRONCHITIS: DOUBLE-BLIND STUDY.
PubMed:ADDITION OF GLYCERYL GUAIACOLATE TO OXTRIPHYLLINE IN CHRONIC ASTHMA: A DOUBLE BLIND STUDY.
PubMed:OBSERVATIONS ON THE HAEMOLYTIC ACTIVITY OF GUAIACOL GLYCEROL ETHER.
PubMed:[EXPERIENCES WITH A NEW ANTIPYRETIC AND ANALGESIC IN A NEW RECTAL CAPSULE FORM].
PubMed:[USE OF REACTIONS TO PSYCHOPHARMACOLOGICAL AGENTS IN THE URINE IN PSYCHIATRIC PRACTICE].
PubMed:[RAPID METHOD FOR DETERMINING GUAIACURAN IN THE URINE].
PubMed:Use of a muscle relaxant salicylate combination in chronic rheumatic diseases.
PubMed:[Ulnar gangrene caused by MY 301 injection into the ulnary artery].
PubMed:INFLUENCE OF GLYCEROL-GUAIACOL-ETHER UPON GASTRIC CHANGES AFTER X-RAY THERAPY.
PubMed:[The influence of o-methoxyphenyl glyceryl ether (My 301) on the rheobase and chronaxy of the gastrocnemius muscle in white rats].
PubMed:[Treatment of Wilson's disease with penicillamine and guajacuran].
PubMed:Comparison of asthmalytic compounds.
PubMed:Theophylline glyceryl guaiacolate (Quibron) in bronchial asthma.
PubMed:[Effect of ataractics on kymo-insufflation curves].
 
Notes:
an expectorant that also has some muscle relaxing action. it is used in many cough preparations. Guaifenesin (INN) or guaiphenesin (former BAN) is an expectorant drug usually taken orally to assist the expectoration ('bringing up') of phlegm from the airways in acute respiratory tract infections. It is a common ingredient in many over-the-counter cough/cold medications. Guaifenesin is also used in the experimental guaifenesin protocol in the treatment of fibromyalgia. It was first approved by the Food and Drug Administration (FDA) in 1952. Guaifenesin works by drawing water into the bronchi. The water both thins mucus and lubricates the airway, facilitating the removal of mucus by coughing. [HMDB]
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