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Category:cosmetic agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Boiling Point: | 275.31 °C. @ 760.00 mm Hg (est)
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| Vapor Pressure: | 0.001000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 249.00 °F. TCC ( 120.30 °C. ) (est)
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| logP (o/w): | -1.293 (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
intravenous-mouse LD50 175 mg/kg
Microvascular Research. Vol. 8, Pg. 320, 1974.
oral-mouse LD50 3000 mg/kg
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 28(12), Pg. 56, 1984.
oral-mouse LD50 > 15000 mg/kg
Drug and Chemical Toxicology. Vol. 1, Pg. 89, 1977/1978.
oral-mouse LD50 45000 mg/kg
Toxicology and Applied Pharmacology. Vol. 16, Pg. 675, 1970.
intraperitoneal-mouse LDLo 5000 mg/kg
Therapie. Vol. 14, Pg. 721, 1959.
intravenous-mouse LDLo 6000 mg/kg
Therapie. Vol. 14, Pg. 721, 1959.
oral-mouse LDLo 15000 mg/kg
Therapie. Vol. 14, Pg. 721, 1959.
oral-rabbit LD50 35000 mg/kg
Toxicology and Applied Pharmacology. Vol. 16, Pg. 675, 1970.
oral-rat LD50 5700 mg/kg
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 28(12), Pg. 56, 1984.
intraperitoneal-rat LDLo 10000 mg/kg
Therapie. Vol. 14, Pg. 721, 1959.
oral-rat LDLo 16000 mg/kg
Toxicology and Applied Pharmacology. Vol. 16, Pg. 675, 1970.
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
inhalation-rat LC50 320 mg/m3/4H
LIVER: OTHER CHANGES
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
KIDNEY, URETER, AND BLADDER: OTHER CHANGES
National Technical Information Service. Vol. OTS0539401
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Safety in Use Information:
| Category: | | cosmetic agents |
| Recommendation for peg/ppg-7/54 copolymer usage levels up to: | | | not for fragrance use.
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| Recommendation for peg/ppg-7/54 copolymer flavor usage levels up to: |
| | not for flavor use.
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Safety References:
European Food Safety Authority (EFSA) reference(s):
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Review of substances/agents that have direct beneficial effect on the environment: mode of action and assessment of efficacy
View page or View pdf
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| EPI System: View |
| Daily Med:search |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| EPA Substance Registry Services (TSCA):9003-11-6 |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :24751 |
| National Institute of Allergy and Infectious Diseases:Data |
| WGK Germany:1 |
| 2-methyloxirane; oxirane (7;54) |
| Chemidplus:0009003116 |
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | methyl oxirane polymer with oxirane (7;54) | | 2- | methyloxirane; oxirane (7;54) | | | oxirane, methyl, polymer with oxirane (7 mol EO, 54 mol PO average molar ratio) | | | poloxamer 331 |
Articles:
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3D/inchi