disodium succinoyl glycyrrhetinate
glycyrrhetinic acid hydrogen succinate, disodium salt

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  CODE136390 CODE136390
  Product(s):
  7421-40-1 Carbenoxolone disodium ≥98%
  The sodium salt form of Carbenoxolone, which has been found to be an anti-infl

CAS Number: 7421-40-1 3D/inchi ECHA EINECS - REACH Pre-Reg: 231-044-0 FDA UNII: F1MP7242Z5 Nikkaji Web: MFCD00079043 Molecular Weight: 614.73049856 Formula: C34 H48 Na2 O7 NMR Predictor: Predict (works with chrome, Edge or firefox) Category:foam boosting, surfactant agents   US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information: Google Scholar: Search Google Books: Search Google Scholar: with word "volatile" Search Google Scholar: with word "flavor" Search Google Scholar: with word "odor" Search Google Patents: Search US Patents: Search EU Patents: Search Pubchem Patents: Search PubMed: Search NCBI: Search   Physical Properties: Assay: 95.00 to 100.00 Food Chemicals Codex Listed: No Boiling Point: 687.40 °C. @ 760.00 mm Hg (est) Flash Point: 413.00 °F. TCC ( 211.60 °C. ) (est) logP (o/w): 7.083 (est) Soluble in:   water, 0.0003503 mg/L @ 25 °C (est)   Organoleptic Properties: Odor and/or flavor descriptions from others (if found).   Cosmetic Information: CosIng: cosmetic data Cosmetic Uses: skin conditioning surfactants surfactant - foam boosting   Suppliers: BOC Sciences For experimental / research use only. Carbenoxolone disodium ≥98% Odor: characteristic Use: The sodium salt form of Carbenoxolone, which has been found to be an anti-infl Santa Cruz Biotechnology For experimental / research use only. Carbenoxolone disodium ≥98% Sigma-Aldrich: Aldrich For experimental / research use only. Carbenoxolone disodium salt ≥98% sds   Safety Information: Preferred SDS: View   Hazards identification   Classification of the substance or mixture GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) None found. GHS Label elements, including precautionary statements   Pictogram   Hazard statement(s) None found. Precautionary statement(s) None found. Oral/Parenteral Toxicity: intraperitoneal-dog LD50 371 mg/kg Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 10, Pg. 710, 1979. intravenous-dog LD50 371 mg/kg CARDIAC: PULSE RATE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Oyo Yakuri. Pharmacometrics. Vol. 11, Pg. 263, 1976. oral-dog LD50 3900 mg/kg Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 10, Pg. 710, 1979. oral-human TDLo 120 mg/kg/6W VASCULAR: BP ELEVATION NOT CHARACTERIZED IN AUTONOMIC SECTION Canadian Medical Association Journal. Vol. 117, Pg. 1155, 1977. intraperitoneal-mouse LD50 120 mg/kg "Symposium on Carbenoxolone Sodium," Robson, J.M., and F.M. Sullivan, eds., London, Butterworth, 1968Vol. -, Pg. 6, 1968. intravenous-mouse LD50 198 mg/kg "Symposium on Carbenoxolone Sodium," Robson, J.M., and F.M. Sullivan, eds., London, Butterworth, 1968Vol. -, Pg. 6, 1968. oral-rabbit LD50 2000 mg/kg "Symposium on Carbenoxolone Sodium," Robson, J.M., and F.M. Sullivan, eds., London, Butterworth, 1968Vol. -, Pg. 6, 1968. intraperitoneal-rat LD50 92 mg/kg Farmaco. Vol. 49, Pg. 281, 1994. oral-rat LD50 2450 mg/kg SKIN AND APPENDAGES (SKIN): HAIR: OTHER LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION CARDIAC: PULSE RATE Oyo Yakuri. Pharmacometrics. Vol. 11, Pg. 263, 1976. Dermal Toxicity: subcutaneous-dog LD50 1060 mg/kg BEHAVIORAL: TREMOR BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) Oyo Yakuri. Pharmacometrics. Vol. 11, Pg. 263, 1976. subcutaneous-rat LD50 1515 mg/kg Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 10, Pg. 710, 1979. Inhalation Toxicity: Not determined   Safety in Use Information: Category: foam boosting, surfactant agents Recommendation for disodium succinoyl glycyrrhetinate usage levels up to:   not for fragrance use.   Recommendation for disodium succinoyl glycyrrhetinate flavor usage levels up to:   not for flavor use.   Safety References: EPI System: View ClinicalTrials.gov:search AIDS Citations:Search Cancer Citations:Search Toxicology Citations:Search EPA ACToR:Toxicology Data EPA Substance Registry Services (SRS):Registry Laboratory Chemical Safety Summary :23899 National Institute of Allergy and Infectious Diseases:Data WGK Germany:3 Chemidplus:0007421401 RTECS:RK0250000 for cas# 7421-40-1   References: NIST Chemistry WebBook: Search Inchi Pubchem (cid): 23899 Pubchem (sid): 134988008   Other Information: (IUPAC): Atomic Weights of the Elements 2011 (pdf) Videos: The Periodic Table of Videos tgsc: Atomic Weights use for this web site (IUPAC): Periodic Table of the Elements HMDB (The Human Metabolome Database): Search ChemSpider: View Wikipedia: View   Potential Blenders and core components note None Found   Potential Uses: None Found   Occurrence (nature, food, other):note   not found in nature   Synonyms:   carbenoxolone disodium   carbenoxolone, disodium salt   glycyrrhetinic acid hydrogen succinate, disodium salt   Articles:   None found yet. Try the PubMed Search.

Notes: an agent derived from licorice root. it is used for the treatment of digestive tract ulcers, especially in the stomach. antidiuretic side effects are frequent, but otherwise the drug is low in toxicity.