PubMed:Preparation of melanin from Catharsius molossus L. and preliminary study on its chemical structure. |
PubMed:Insights into the aggregation/deposition and structure of a polydopamine film. |
PubMed:Artificial biomelanin: highly light-absorbing nano-sized eumelanin by biomimetic synthesis in chicken egg white. |
PubMed:Superior photoprotective motifs and mechanisms in eumelanins uncovered. |
PubMed:Melanization reaction products of shrimp display antimicrobial properties against their major bacterial and fungal pathogens. |
PubMed:Effects of the melanin precursor 5,6-dihydroxy-indole-2-carboxylic acid (DHICA) on DNA damage and repair in the presence of reactive oxygen species. |
PubMed:Effect of pH on elementary steps of dopachrome conversion from first-principles calculation. |
PubMed:Characterization of carbonized polydopamine nanoparticles suggests ordered supramolecular structure of polydopamine. |
PubMed:Degree of polymerization of 5,6-dihydroxyindole-derived eumelanin from chemical degradation study. |
PubMed:Tuning heterogeneous poly(dopamine) structures and mechanics: in silico covalent cross-linking and thin film nanoindentation. |
PubMed:Towards eumelanin@zeolite hybrids: pore-size-controlled 5,6-dihydroxyindole polymerization. |
PubMed:Comparison of synthetic dopamine-eumelanin formed in the presence of oxygen and Cu2+ cations as oxidants. |
PubMed:Free radical coupling of o-semiquinones uncovered. |
PubMed:Neutral pH and copper ions promote eumelanogenesis after the dopachrome stage. |
PubMed:Self-assembly of tetramers of 5,6-dihydroxyindole explains the primary physical properties of eumelanin: experiment, simulation, and design. |
PubMed:High-performance liquid chromatography estimation of cross-linking of dihydroxyindole moiety in eumelanin. |
PubMed:Bottom-up approach to eumelanin photoprotection: emission dynamics in parallel sets of water-soluble 5,6-dihydroxyindole-based model systems. |
PubMed:Intermolecular π-electron perturbations generate extrinsic visible contributions to eumelanin black chromophore in model polymers with interrupted interring conjugation. |
PubMed:Synthesis and Agonistic Activity at the GPR35 of 5,6-Dihydroxyindole-2-carboxylic Acid Analogues. |
PubMed:Eumelanin buildup on the nanoscale: aggregate growth/assembly and visible absorption development in biomimetic 5,6-dihydroxyindole polymerization. |
PubMed:Multiple tyrosine metabolites are GPR35 agonists. |
PubMed:The eumelanin intermediate 5,6-dihydroxyindole-2-carboxylic acid is a messenger in the cross-talk among epidermal cells. |
PubMed:Exploring the frontiers of synthetic eumelanin polymers by high-resolution matrix-assisted laser/desorption ionization mass spectrometry. |
PubMed:Metabolomic profiling reveals that Drosophila melanogaster larvae with the y mutation have altered lysine metabolism. |
PubMed:Age-dependent changes in eumelanin composition in hairs of various ethnic origins. |
PubMed:UV-absorption spectra of melanosomes containing varying 5,6-dihydroxyindole and 5,6-dihydroxyindole-2-carboxylic acid content. |
PubMed:New pathways of betanidin and betanin enzymatic oxidation. |
PubMed:Inactivation of tautomerase activity of macrophage migration inhibitory factor by sulforaphane: a potential biomarker for anti-inflammatory intervention. |
PubMed:Antiviral, anti-parasitic, and cytotoxic effects of 5,6-dihydroxyindole (DHI), a reactive compound generated by phenoloxidase during insect immune response. |
PubMed:π-Electron manipulation of the 5,6-dihydroxyindole/quinone system by 3-alkynylation: mild acid-mediated entry to (cross)-conjugated scaffolds and paradigms for medium-tunable chromophores. |
PubMed:Usefulness of alkaline hydrogen peroxide oxidation to analyze eumelanin and pheomelanin in various tissue samples: application to chemical analysis of human hair melanins. |
PubMed:Maintenance of immune hyporesponsiveness to melanosomal proteins by DHICA-mediated antioxidation: Possible implications for autoimmune vitiligo. |
PubMed:First synthetic entry to the trimer stage of 5,6-dihydroxyindole polymerization: ortho-alkynylaniline-based access to the missing 2,7':2',7''-triindole. |
PubMed:Cyclic structural motifs in 5,6-dihydroxyindole polymerization uncovered: biomimetic modular buildup of a unique five-membered macrocycle. |
PubMed:UV-dissipation mechanisms in the eumelanin building block DHICA. |
PubMed:5,6-Dihydroxyindole oxidation in phosphate buffer/polyvinyl alcohol: a new model system for studies of visible chromophore development in synthetic eumelanin polymers. |
PubMed:Regulation of DHICA-mediated antioxidation by dopachrome tautomerase: implication for skin photoprotection against UVA radiation. |
PubMed:Direct measurement of the ultraviolet absorption coefficient of single retinal melanosomes. |
PubMed:Disentangling eumelanin "black chromophore": visible absorption changes as signatures of oxidation state- and aggregation-dependent dynamic interactions in a model water-soluble 5,6-dihydroxyindole polymer. |
PubMed:Ultrafast excited state dynamics of 5,6-dihydroxyindole, a key eumelanin building block: nonradiative decay mechanism. |
PubMed:Efficient synthesis of 5,6-dihydroxyindole dimers, key eumelanin building blocks, by a unified o-ethynylaniline-based strategy for the construction of 2-linked biindolyl scaffolds. |
PubMed:Lack of visible chromophore development in the pulse radiolysis oxidation of 5,6-dihydroxyindole-2-carboxylic acid oligomers: DFT investigation and implications for eumelanin absorption properties. |
PubMed:Dopamine and the dopamine oxidation product 5,6-dihydroxylindole promote distinct on-pathway and off-pathway aggregation of alpha-synuclein in a pH-dependent manner. |
PubMed:Structural, electrical, electronic and optical properties of melanin films. |
PubMed:Role of solvent, pH, and molecular size in excited-state deactivation of key eumelanin building blocks: implications for melanin pigment photostability. |
PubMed:Possible oxidative polymerization mechanism of 5,6-dihydroxyindole from ab initio calculations. |
PubMed:Skin-lightening products revisited. |
PubMed:Structural effects on the electronic absorption properties of 5,6-dihydroxyindole oligomers: the potential of an integrated experimental and DFT approach to model eumelanin optical properties. |
PubMed:Chemistry of mixed melanogenesis--pivotal roles of dopaquinone. |
PubMed:Ultra-low temperature oxidation of 5,6-dihydroxyindole: a novel approach to study synthetic melanogenesis. |
PubMed:Synthesis and polymerization studies of organic-soluble eumelanins. |
PubMed:Solvochromic effects in model eumelanin compounds. |
PubMed:Effect of dimerization on vibrational spectra of eumelanin precursors. |
PubMed:Melanin precursor 5,6-dihydroxyindol: protective effects and cytotoxicity on retinal cells in vitro and in vivo. |
PubMed:Hyperbranched molecular structures with potential antiviral activity: derivatives of 5,6-dihydroxyindole-2-carboxylic Acid. |
PubMed:5,6-dihydroxyindole tetramers with "anomalous" interunit bonding patterns by oxidative coupling of 5,5',6,6'-tetrahydroxy-2,7'-biindolyl: emerging complexities on the way toward an improved model of eumelanin buildup. |
PubMed:Transition dipole strength of eumelanin. |
PubMed:Oxidation chemistry of norepinephrine: partitioning of the O-quinone between competing cyclization and chain breakdown pathways and their roles in melanin formation. |
PubMed:Parasite suppression of the oxidations of eumelanin precursors in Drosophila melanogaster. |
PubMed:Broad-spectrum antimicrobial activity of the reactive compounds generated in vitro by Manduca sexta phenoloxidase. |
PubMed:The melanogenic system of the liver pigmented macrophages of Rana esculenta L.--tyrosinase activity. |
PubMed:Changes of melanosome morphology associated with the differentiation of epidermal melanocytes in slaty mice. |
PubMed:Kinetic and structural analysis of the early oxidation products of dopamine: analysis of the interactions with alpha-synuclein. |
PubMed:Evaluation of efficacy and safety of rucinol serum in patients with melasma: a randomized controlled trial. |
PubMed:The first 5,6-dihydroxyindole tetramer by oxidation of 5,5',6,6'-tetrahydroxy- 2,4'-biindolyl and an unexpected issue of positional reactivity en route to eumelanin-related polymers. |
PubMed:Photophysics of eumelanin: ab initio studies on the electronic spectroscopy and photochemistry of 5,6-dihydroxyindole. |
PubMed:Short-lived quinonoid species from 5,6-dihydroxyindole dimers en route to eumelanin polymers: integrated chemical, pulse radiolytic, and quantum mechanical investigation. |
PubMed:Dopaquinone redox exchange with dihydroxyindole and dihydroxyindole carboxylic acid. |
PubMed:Synthesis, discovery and mechanism of 2,6-dimethoxy-N-(4-methoxyphenyl)benzamide as potent depigmenting agent in the skin. |
PubMed:Quantitative fluorescence excitation spectra of synthetic eumelanin. |
PubMed:Fe(III)-coordination properties of neuromelanin components: 5,6-dihydroxyindole and 5,6-dihydroxyindole-2-carboxylic acid. |
PubMed:Role of dopachrome conversion enzyme in the melanization of filarial worms in mosquitoes. |
PubMed:An oxygen transporter hemocyanin can act on the late pathway of melanin synthesis. |
PubMed:[UV-Vis spectroscopic study of aluminum-manganese cooperative effect on the melanin formation from DOPA oxidation]. |
PubMed:[UV-vis spectroscopic study of the effect of Cu(II) ions on dopachrome]. |
PubMed:Comparisons of the structural and chemical properties of melanosomes isolated from retinal pigment epithelium, iris and choroid of newborn and mature bovine eyes. |
PubMed:Metal-ion interactions and the structural organization of Sepia eumelanin. |
PubMed:Comparison of structural and chemical properties of black and red human hair melanosomes. |
PubMed:Design and synthesis of novel dihydroxyindole-2-carboxylic acids as HIV-1 integrase inhibitors. |
PubMed:Aluminum facilitation of the iron-mediated oxidation of DOPA to melanin. |
PubMed:Involvement of photooxidation of melanogenic precursors in prolonged pigmentation induced by ultraviolet A. |
PubMed:Benzylamide derivative compound attenuates the ultraviolet B-induced hyperpigmentation in the brownish guinea pig skin. |
PubMed:Changes in the proliferation and differentiation of neonatal mouse pink-eyed dilution melanocytes in the presence of excess tyrosine. |
PubMed:Aluminum ions accelerated the oxidative stress of copper-mediated melanin formation. |
PubMed:Melanogenesis in the ink gland of Sepia officinalis. |
PubMed:Neurotoxicity due to o-quinones: neuromelanin formation and possible mechanisms for o-quinone detoxification. |
PubMed:Melanin as a target for melanoma chemotherapy: pro-oxidant effect of oxygen and metals on melanoma viability. |
PubMed:The IFPCS presidential lecture: a chemist's view of melanogenesis. |
PubMed:Effect of aluminum (III) on the conversion of dopachrome in the melanin synthesis pathway. |
PubMed:Cocaine, benzoylecgonine, amphetamine, and N-acetylamphetamine binding to melanin subtypes. |
PubMed:Identification of Drosophila melanogaster yellow-f and yellow-f2 proteins as dopachrome-conversion enzymes. |
PubMed:Stimulation of the proliferation and differentiation of mouse pink-eyed dilution epidermal melanocytes by excess tyrosine in serum-free primary culture. |
PubMed:Redox behavior of melanins: direct electrochemistry of dihydroxyindole-melanin and its Cu and Zn adducts. |
PubMed:Comparative biochemistry of eumelanogenesis and the protective roles of phenoloxidase and melanin in insects. |
PubMed:Acid-Promoted Competing Pathways in the Oxidative Polymerization of 5,6-Dihydroxyindoles and Related Compounds: Straightforward Cyclotrimerization Routes to Diindolocarbazole Derivatives. |
PubMed:Variation in melanin content and composition in type V and VI photoexposed and photoprotected human skin: the dominant role of DHI. |
PubMed:Cloning and characterization of a dopachrome conversion enzyme from the yellow fever mosquito, Aedes aegypti. |
PubMed:Melanogenesis by tyrosinase action on 3,4-dihydroxyphenylalanine (DOPA) in the presence of polyethylene glycol: a matrix-assisted laser desorption/ionization mass spectrometric investigation. |
PubMed:Interaction of major coat color gene functions in mice as studied by chemical analysis of eumelanin and pheomelanin. |
PubMed:Relationship of melanin degradation products to actual melanin content: application to human hair. |
PubMed:The 5,6-dihydroxyindole-2-carboxylic acid (DHICA) oxidase activity of human tyrosinase. |
PubMed:TYRP2-mediated resistance to cis-diamminedichloroplatinum (II) in human melanoma cells is independent of tyrosinase and TYRP1 expression and melanin content. |
PubMed:Macrophage migration inhibitory factor (MIF): its essential role in the immune system and cell growth. |
PubMed:Effects of ultraviolet irradiation on melanogenesis from tyrosine, Dopa and dopamine: a matrix-assisted laser desorption/ionization mass spectrometric study. |
PubMed:Tyrosinase-induced cross-linking of tyrosine-containing peptides investigated by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. |
PubMed:Isolation and characterization of mammalian eumelanins from hair and irides. |
PubMed:Absolute rate constants for the quenching of reactive excited states by melanin and related 5,6-dihydroxyindole metabolites: implications for their antioxidant activity. |
PubMed:Macrophage migration inhibitory factor (MIF)--its role in catecholamine metabolism. |
PubMed:Cross-polarization/magic-angle-spinning nuclear magnetic resonance in selectively 13C-labeled synthetic eumelanins. |
PubMed:A method for detecting dopaminechrome isomerase activity on gels. |
PubMed:5,6-Dihydroxyindoles in the fenton reaction: a model study of the role of melanin precursors in oxidative stress and hyperpigmentary processes. |
PubMed:Enzymatically inactive macrophage migration inhibitory factor inhibits monocyte chemotaxis and random migration. |
PubMed:Application of matrix-assisted laser desorption/ionization mass spectrometry to the detection of melanins formed from Dopa and dopamine. |
PubMed:The soluble eumelanin precursor 5,6-dihydroxyindole-2-carboxylic acid enhances oxidative damage in human keratinocyte DNA after UVA irradiation. |
PubMed:The depigmenting effect of alpha-tocopheryl ferulate on human melanoma cells. |
PubMed:Insect melanogenesis. II. Inability of Manduca phenoloxidase to act on 5,6-dihydroxyindole-2-carboxylic acid. |
PubMed:Lipoxygenase/H2O2-catalyzed oxidation of dihdroxyindoles: synthesis of melanin pigments and study of their antioxidant properties. |
PubMed:Cloning of the mouse gene for D-dopachrome tautomerase. |
PubMed:Tyrosinase stabilization by Tyrp1 (the brown locus protein). |
PubMed:Cooperation of dopachrome conversion factor with phenoloxidase in the eumelanin pathway in haemolymph of Locusta migratoria (Insecta). |
PubMed:Nitric oxide-induced oxidation of 5,6-dihydroxyindole and 5,6-dihydroxyindole-2-carboxylic acid under aerobic conditions: non-enzymatic route to melanin pigments of potential relevance to skin (photo)protection. |
PubMed:Role of neurofibromin in modulation of expression of the tyrosinase-related protein 2 gene. |
PubMed:Human tyrosinase related protein-1 (TRP-1) does not function as a DHICA oxidase activity in contrast to murine TRP-1. |
PubMed:Lactoperoxidase-catalyzed oxidation of melanin by reactive nitrogen species derived from nitrite (NO2-): an EPR study. |
PubMed:Chemical degradation of melanins: application to identification of dopamine-melanin. |
PubMed:Production of melanins by ceruloplasmin. |
PubMed:Molecular cloning of human D-dopachrome tautomerase cDNA: N-terminal proline is essential for enzyme activation. |
PubMed:The protein catalysing the conversion of D-dopachrome to 5,6-dihydroxyindole is a phenylpyruvate tautomerase (EC 5.3.2.1) |
PubMed:Selective incorporation of the prototype melanoma seeker thiourea into nascent melanin: a chemical insight. |
PubMed:Substrate specificity for isomerase activity of macrophage migration inhibitory factor and its inhibition by indole derivatives. |
PubMed:Crystallization and preliminary X-ray analysis of human D-dopachrome tautomerase. |
PubMed:NMR characterization of physicochemical properties of rat D-dopachrome tautomerase. |
PubMed:Diffusible melanin-related metabolites are potent inhibitors of lipid peroxidation. |
PubMed:Chemical characterization of eumelanins with special emphasis on 5,6-dihydroxyindole-2-carboxylic acid content and molecular size. |
PubMed:Molecular approach to the nucleo-melanosomal interaction in human melanoma cells. |
PubMed:Mechanism of selective incorporation of the melanoma seeker 2-thiouracil into growing melanin. |
PubMed:Mouse fibroblast expressing human tyrosinase with DHICA-oxidase activity produces predominantly pheomelanin deposit in lysosome. |
PubMed:Negative ion electrospray mass spectrometry of polyphenols, catecholamines and their oxidation products. |
PubMed:Hydrogen peroxide generation associated with the oxidations of the eumelanin precursors 5,6-dihydroxyindole and 5,6-dihydroxyindole-2-carboxylic acid. |
PubMed:Composition of mammalian eumelanins: analyses of DHICA-derived units in pigments from hair and melanoma cells. |
PubMed:Chemical characterization of melanins in sheep wool and human hair. |
PubMed:Polymerization of 5,6-dihydroxyindole-2-carboxylic acid to melanin by the pmel 17/silver locus protein. |
PubMed:Molecular mechanism for catalysis by a new zinc-enzyme, dopachrome tautomerase. |
PubMed:The immunoregulatory mediator macrophage migration inhibitory factor (MIF) catalyzes a tautomerization reaction. |
PubMed:5,6-Dihydroxyindole-2-carboxylic acid, a diffusible melanin precursor, is a potent stimulator of lipopolysaccharide-induced production of nitric oxide by J774 macrophages. |
PubMed:Cloning and sequencing of a cDNA encoding rat D-dopachrome tautomerase. |
PubMed:Chemical characterization of hair melanins in various coat-color mutants of mice. |
PubMed:Modulation of melanogenic protein expression during the switch from eu- to pheomelanogenesis. |
PubMed:Dual role of melanins and melanin precursors as photoprotective and phototoxic agents: inhibition of ultraviolet radiation-induced lipid peroxidation. |
PubMed:The expression of tyrosinase, tyrosinase-related proteins 1 and 2 (TRP1 and TRP2), the silver protein, and a melanogenic inhibitor in human melanoma cells of differing melanogenic activities. |
PubMed:Some aspects of melanin formation of melanocytes cultured on collagen-coated microcarrier beads. |
PubMed:Generation of the neurotoxin 6-hydroxydopamine by peroxidase/H2O2 oxidation of dopamine. |
PubMed:Tyrosinase related protein 1 (TRP1) functions as a DHICA oxidase in melanin biosynthesis. |
PubMed:Egg chorion tanning in Aedes aegypti mosquito. |
PubMed:Dopachrome conversion activity in Aedes aegypti: significance during melanotic encapsulation of parasites and cuticular tanning. |
PubMed:One-electron oxidation of C(2) and C(3) methyl substituted 5,6-dihydroxyindoles: model pathways of melanogenesis. |
PubMed:Dopachrome tautomerase is a zinc-containing enzyme. |
PubMed:The mouse brown (b) locus protein functions as a dopachrome tautomerase. |
PubMed:Specific incorporation of 2-thiouracil into biological melanins. |
PubMed:Characterization of peroxidative oxidation products of dopamine by mass spectrometry. |
PubMed:DHICA oxidase activity of TRP1 and interactions with other melanogenic enzymes. |
PubMed:A new enzymatic function in the melanogenic pathway. The 5,6-dihydroxyindole-2-carboxylic acid oxidase activity of tyrosinase-related protein-1 (TRP1). |
PubMed:Detection of dopachrome isomerase activity on gels. |
PubMed:A new dopachrome-rearranging enzyme from the ejected ink of the cuttlefish Sepia officinalis. |
PubMed:The inherent cytotoxicity of melanin precursors: a revision. |
PubMed:Evaluation of melanin-related metabolites as markers of melanoma progression. |
PubMed:Dopachrome tautomerase decreases the binding of indolic melanogenesis intermediates to proteins. |
PubMed:A 13C solid-state NMR study of the structure and auto-oxidation process of natural and synthetic melanins. |
PubMed:Isolation of a new tautomerase monitored by the conversion of D-dopachrome to 5,6-dihydroxyindole. |
PubMed:Spectrophotometric assay of eumelanin in tissue samples. |
PubMed:The mouse brown (b) locus protein has dopachrome tautomerase activity and is located in lysosomes in transfected fibroblasts. |
PubMed:Regulatory factors for polymerization of melanin monomers within coated vesicles and premelanosomes in melanoma cells. |
PubMed:Inhibitory effect of melanin precursors on arachidonic acid peroxidation. |
PubMed:Metabolism of 3-indolylacetic acid during percutaneous absorption in human skin. |
PubMed:Exploitation of pigment biosynthesis pathway as a selective chemotherapeutic approach for malignant melanoma. |
PubMed:Differences in subcellular distribution of catechol-O-methyltransferase and tyrosinase in malignant melanoma. |
PubMed:Dynamics of melanogenesis intermediates. |
PubMed:Preparation of monoclonal mouse antibodies against two specific eu-melanin related compounds. |
PubMed:Mutational mapping of the catalytic activities of human tyrosinase. |
PubMed:Functional properties of cloned melanogenic proteins. |
PubMed:5,6-Dihydroxyindole-2-carboxylic acid is incorporated in mammalian melanin. |
PubMed:Synthesis and characterization of melanins from dihydroxyindole-2-carboxylic acid and dihydroxyindole. |
PubMed:Regulation of the final phase of mammalian melanogenesis. The role of dopachrome tautomerase and the ratio between 5,6-dihydroxyindole-2-carboxylic acid and 5,6-dihydroxyindole. |
PubMed:Evidence that dopachrome tautomerase is a ferrous iron-binding glycoprotein. |
PubMed:Measurement of eumelanin precursor metabolites in the urine as a new marker for melanoma metastases. |
PubMed:Reduced cellular immune competence of a temperature-sensitive dopa decarboxylase mutant strain of Drosophila melanogaster against the parasite Leptopilina boulardi. |
PubMed:A second tyrosinase-related protein, TRP-2, is a melanogenic enzyme termed DOPAchrome tautomerase. |
PubMed:Identification of 3,4-dihydroxyphenylalanine, 5,6-dihydroxyindole, and N-acetylarterenone during eumelanin formation in immune reactive larvae of Drosophila melanogaster. |
PubMed:The role of peroxidase in melanogenesis revisited. |
PubMed:Comparative action of dopachrome tautomerase and metal ions on the rearrangement of dopachrome. |
PubMed:Electrochemical identification of dopachrome isomerase in Drosophila melanogaster. |
PubMed:Specificity of dopachrome tautomerase and inhibition by carboxylated indoles. Considerations on the enzyme active site. |
PubMed:Quinone methide as a new intermediate in eumelanin biosynthesis. |
PubMed:Peroxidase as an alternative to tyrosinase in the oxidative polymerization of 5,6-dihydroxyindoles to melanin(s). |
PubMed:After dopachrome? |
PubMed:Determination of catechol O-methyltransferase activity in relation to melanin metabolism using high-performance liquid chromatography with fluorimetric detection. |
PubMed:A pulse radiolysis investigation of the oxidation of methoxylated metabolites of indolic melanin precursors. |
PubMed:Regulation of mammalian melanogenesis. I: Partial purification and characterization of a dopachrome converting factor: dopachrome tautomerase. |
PubMed:A new spectrophotometric assay for dopachrome tautomerase. |
PubMed:Mutagenicity test for unstable compounds, such as 5,6-dihydroxyindole, using an Escherichia coli HB101/pBR322 transfection system. |
PubMed:A pulse radiolysis investigation of the oxidation of indolic melanin precursors: evidence for indolequinones and subsequent intermediates. |
PubMed:Correlation between urinary melanin-related metabolites and tumour weight in melanoma-bearing mice. |
PubMed:Liposome-entrapped tyrosinase: a tool to investigate the regulation of the Raper-Mason pathway. |
PubMed:Function of dopachrome oxidoreductase and metal ions in dopachrome conversion in the eumelanin pathway. |
PubMed:Melanin monomers within coated vesicles and premelanosomes in melanin synthesizing cells. |
PubMed:Preparation of eumelanin-related metabolites 5,6-dihydroxyindole, 5,6-dihydroxyindole-2-carboxylic acid, and their O-methyl derivatives. |
PubMed:Melanogenesis in Cryptococcus neoformans. |
PubMed:Structural modifications in biosynthetic melanins induced by metal ions. |
PubMed:Some indolic compounds as markers of the melanocyte activity. |
PubMed:Activation of tyrosinase in mouse melanoma cell cultures. |
PubMed:Effect of metal ions on the rearrangement of dopachrome. |
PubMed:Photogeneration of free radicals from eumelanogenic intermediates and metabolites. |
PubMed:Restriction patterns of model DNA treated with 5,6-dihydroxyindole, a potent cytotoxic intermediate of melanin synthesis: effect of u.v. irradiation. |
PubMed:Reexamination of the structure of eumelanin. |
PubMed:Eumelanin-related indolic compounds in the urine of treated melanoma patients. |
PubMed:Synthesis in vitro of 5,6-dihydroxyindole-2-carboxylic acid by dopachrome conversion factor from Cloudman S91 melanoma cells. |
PubMed:5,6-Dihydroxyindole oxidation by mammalian, mushroom and amphibian tyrosinase preparations. |
PubMed:A spectrophotometric assay for mammalian tyrosinase utilizing the formation of melanochrome from L-dopa. |
PubMed:Decreased dopachrome oxidoreductase activity in yellow mice. |
PubMed:Dopachrome oxidoreductase: a new enzyme in the pigment pathway. |
PubMed:A new possible pathogenesis of some gallstones. |
PubMed:Identification of 5-hydroxy-6-indolyl-O-sulfate in urine of patients with malignant melanoma. |
PubMed:Tyrosinase-like activity in normal human substantia nigra. |
PubMed:New regulatory factors for melanogenesis: developmental changes in neonatal mice of various genotypes. |
PubMed:A quantitative method for determination of 5,6-dihydroxyindole-2-carboxylic acid using high-pressure liquid chromatography with fluorometric detection. |
PubMed:Eumelanin (precursor) metabolites as markers for pigmented malignant melanoma: a preliminary report. |
PubMed:Dopa oxidation and tyrosine oxygenation by human melanoma tyrosinase. |
PubMed:Demonstration of 5,6-dihydroxyindole-2-carboxylic acid, a melanin precursor, in normal urine. |
PubMed:Mammalian tyrosinase catalyzes three reactions in the biosynthesis of melanin. |
PubMed:DNA damage and selective toxicity of dopa and ascorbate:copper in human melanoma cells. |
PubMed:The role of pH in the melanin biosynthesis pathway. |
PubMed:New regulators of melanogenesis are associated with purified tyrosinase isozymes. |
PubMed:Catechol O-methyltransferase. 12. Affinity labeling the active site with the oxidation products of 5,6-dihydroxyindole. |
PubMed:A qualitative gas chromatographic analysis of substituted 5,6-dihydroxyindoles from the urine of patients with melanoma. |
PubMed:The identification of Thormählen positive melanogen "A" from the urine of melanoma patients as 6-methoxy-5-indolylglucosiduronate. |
PubMed:5,6-Dihydroxyindole is a melanin precursor showing potent cytotoxicity. |
PubMed:Isolation of oligomers of 5,6-dihydroxyindole-2-carboxylic acid from the eye of the catfish. |
PubMed:5,6-Dihydroxyindole formation from oxidized 6-hydroxydopamine. |