tetracaine
benzoic acid, 4-(butylamino)-, 2-(dimethylamino)ethyl ester

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  CODE136264 CODE136264
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  TCBNIP Tetracaine Base USP

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  94-24-6 Tetracaine

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  GL2126 Tetracaine

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  T2789 Tetracaine >98.0%(GC)(T)
  SDS

Name: 2-(dimethylamino)ethyl 4-(butylamino)benzoate CAS Number: 94-24-6 3D/inchi ECHA EINECS - REACH Pre-Reg: 202-316-6 FDA UNII: 0619F35CGV Nikkaji Web: J3.945D Beilstein Number: 2216051 MDL: MFCD00053787 XlogP3: 3.70 (est) Molecular Weight: 264.36868000 Formula: C15 H24 N2 O2 BioActivity Summary: listing NMR Predictor: Predict (works with chrome, Edge or firefox) Category:pharmaceuticals / chemical synthisis   US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information: Google Scholar: Search Google Books: Search Google Scholar: with word "volatile" Search Google Scholar: with word "flavor" Search Google Scholar: with word "odor" Search Google Patents: Search US Patents: Search EU Patents: Search Pubchem Patents: Search PubMed: Search NCBI: Search   Physical Properties: Assay: 95.00 to 100.00 Food Chemicals Codex Listed: No Boiling Point: 389.36 °C. @ 760.00 mm Hg (est) Flash Point: 373.00 °F. TCC ( 189.30 °C. ) (est) logP (o/w): 3.510 Soluble in:   water, 201.4 mg/L @ 25 °C (est)   Organoleptic Properties: Odor and/or flavor descriptions from others (if found).   Cosmetic Information: None found   Suppliers: American International Chemical, LLC. Tetracaine Base USP BOC Sciences For experimental / research use only. Tetracaine Glentham Life Sciences Tetracaine Sigma-Aldrich: Sigma For experimental / research use only. Tetracaine ≥98% (TLC) sds TCI AMERICA For experimental / research use only. Tetracaine >98.0%(GC)(T) sds   Safety Information: Preferred SDS: View   Hazards identification   Classification of the substance or mixture GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) None found. GHS Label elements, including precautionary statements   Pictogram   Hazard statement(s) None found. Precautionary statement(s) None found. Oral/Parenteral Toxicity: parenteral-frog LDLo 200 mg/kg LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES CARDIAC: OTHER CHANGES BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 168, Pg. 447, 1932. parenteral-man LDLo 1 mg/kg BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) BEHAVIORAL: COMA LUNGS, THORAX, OR RESPIRATION: CYANOSIS Sammlung von Vergiftungsfaellen. Vol. 10, Pg. 5C, 1939. intraperitoneal-mouse LD50 20 mg/kg Russian Pharmacology and Toxicology Vol. 35, Pg. 114, 1972. intravenous-mouse LD50 6 mg/kg European Journal of Medicinal Chemistry--Chimie Therapeutique. Vol. 10, Pg. 291, 1975. oral-mouse LD50 300 mg/kg Helvetica Physiologia et Pharmacologica Acta. Vol. 15, Pg. 55, 1957. intratracheal-rabbit LD50 6500 ug/kg Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 78, 1976. parenteral-rabbit LD50 33500 ug/kg Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 78, 1976. intravenous-rabbit LDLo 6 mg/kg LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 160, Pg. 53, 1931. intraperitoneal-rat LD50 33 mg/kg Klinische Wochenscrift. Vol. 31, Pg. 97, 1953. intratracheal-rat LD50 4 mg/kg Klinische Wochenscrift. Vol. 31, Pg. 97, 1953. intravenous-rat LD50 6 mg/kg Arzneimittel-Forschung. Drug Research. Vol. 8, Pg. 539, 1958. Dermal Toxicity: subcutaneous-mouse LD50 41500 ug/kg Arzneimittel-Forschung. Drug Research. Vol. 7, Pg. 215, 1957. subcutaneous-rabbit LDLo 20 mg/kg LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 160, Pg. 53, 1931. Inhalation Toxicity: Not determined   Safety in Use Information: Category: pharmaceuticals / chemical synthisis Recommendation for tetracaine usage levels up to:   not for fragrance use.   Recommendation for tetracaine flavor usage levels up to:   not for flavor use.   Safety References: EPI System: View ClinicalTrials.gov:search Daily Med:search AIDS Citations:Search Cancer Citations:Search Toxicology Citations:Search EPA ACToR:Toxicology Data EPA Substance Registry Services (SRS):Registry Laboratory Chemical Safety Summary :5411 National Institute of Allergy and Infectious Diseases:Data WGK Germany:3 2-(dimethylamino)ethyl 4-(butylamino)benzoate Chemidplus:0000094246 RTECS:DG4725000 for cas# 94-24-6   References:   2-(dimethylamino)ethyl 4-(butylamino)benzoate NIST Chemistry WebBook: Search Inchi Pubchem (cid): 5411 Pubchem (sid): 134970961   Other Information: (IUPAC): Atomic Weights of the Elements 2011 (pdf) Videos: The Periodic Table of Videos tgsc: Atomic Weights use for this web site (IUPAC): Periodic Table of the Elements CHEBI: View CHEMBL: View KEGG (GenomeNet): C07526 HMDB (The Human Metabolome Database): Search Export Tariff Code: 2922.49.3700 ChemSpider: View Wikipedia: View   Potential Blenders and core components note None Found   Potential Uses: None Found   Occurrence (nature, food, other):note   not found in nature   Synonyms:   amethocaine   anetain   benzoic acid, 4-(butylamino)-, 2-(dimethylamino)ethyl ester 4- butylamino-benzoic acid 2-dimethylamino-ethyl ester 4-( butylamino)benzoic acid 2-(dimethylamino)ethyl ester p-( butylamino)benzoic acid, 2-(dimethylamino)ethyl ester p- butylaminobenzoyl-2-dimethylaminoethanol   contralgin   dicaine   dikain 2-( dimethylamino)ethyl 4-(butylamino)benzoate 2-( dimethylamino)ethyl p-(butylamino)benzoate   fissucain   intercain   laudocaine   medicaine   meethobalm   metraspray   mucaesthin   pontocaine   rexocaine   synera   uromucaesthin   Articles:   None found yet. 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Notes: a potent local anesthetic of the ester type used for surface and spinal anesthesia.