EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

riboflavin 5'-phosphate sodium
riboflavin 5'-(dihydrogen phosphate) sodium salt (1:1)

Supplier Sponsors

Name:sodium [(2S,3R,4R)-5-(7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10-yl)-2,3,4-trihydroxypentyl] hydrogen phosphate
CAS Number: 130-40-5Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:204-988-6
FDA UNII: 957E53WV42
Beilstein Number:4106529
MDL:MFCD00065362
Molecular Weight:478.33073128
Formula:C17 H20 N4 Na O9 P
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:nutrient supplements
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Google Patents:Search
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Pubchem Patents:Search
PubMed:Search
NCBI:Search
JECFA Food Additive: Riboflavin 5'-Phosphate Sodium
GSFA Codex: Riboflavin 5'-phosphate sodium (101(ii))
FDA Mainterm (SATF):130-40-5 ; RIBOFLAVIN 5'-PHOSPHATE, SODIUM
FDA Regulation:
FDA PART 184 -- DIRECT FOOD SUBSTANCES AFFIRMED AS GENERALLY RECOGNIZED AS SAFE
Subpart B--Listing of Specific Substances Affirmed as GRAS
Sec. 184.1697 Riboflavin-5'-phosphate (sodium).
 
Physical Properties:
Appearance:orange yellow crystalline powder (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
logP (o/w): -2.193 (est)
Soluble in:
 water, 7.688e+005 mg/L @ 25 °C (est)
Insoluble in:
 alcohol
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: skin conditioning
 
Suppliers:
American International Chemical, LLC.
Riboflavin-5’-Phosphate Sodium (RPS)
BOC Sciences
For experimental / research use only.
Riboflavin-5"-Phosphate Sodium 98%
Odor: characteristic
Use: Riboflavin phosphate sodium, a Riboflavin derivative, is a commonly existed nutritional factor and could improve the biomechanical stiffness of corneal. Riboflavin phosphate sodium is a commonly existed nutritional factor and could improve the biomechanical stiffness o
Carbosynth
For experimental / research use only.
Riboflavin 5'-phosphate sodium salt
Charkit Chemical
RIBOFLAVIN 5 PHOSPHATE
Glentham Life Sciences
Riboflavin-5'-phosphate monosodium salt hydrate, USP grade
Penta International
RIBOFLAVIN-5-PHOSPHATE SODIUM SALT USP GRADE
Penta International
RIBOFLAVIN-5-PHOSPHATE SODIUM SALT
Rung International
Riboflavin
Odor: characteristic
Use: Riboflavin- 5-Sodium Phosphate is a more soluble form of Riboflavin. Riboflavin, also known as Vitamin B2. Commercially prepared from yeast, it is also manufactured synthetically.
Santa Cruz Biotechnology
For experimental / research use only.
Riboflavin 5'-Monophosphate Sodium Salt >93%
Sigma-Aldrich: Sigma
For experimental / research use only.
Riboflavin 5'-monophosphate sodium salt hydrate synthetic, ≥70% (HPLC)
sds
TCI AMERICA
For experimental / research use only.
Riboflavin 5'-Monophosphate Sodium Salt >93.0%(E)
sds
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
nutrient supplements
Recommendation for riboflavin 5'-phosphate sodium usage levels up to:
 not for fragrance use.
 
Recommendation for riboflavin 5'-phosphate sodium flavor usage levels up to:
 not for flavor use.
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Scientific Opinion on the re-evaluation of riboflavin (E 101(i)) and riboflavin-5'-phosphate sodium (E 101(ii)) as food additives
View page or View pdf

Assessment of one published review on health risks associated with phosphate additives in food
View page or View pdf

Safety and efficacy of vitamin B2 (riboflavin and riboflavin 5’-phosphate ester monosodium salt) produced by Bacillus subtilis for all animal species based on a dossier submitted by DSM
View page or View pdf

Safety and efficacy of vitamin B2 (riboflavin 5'-phosphate ester monosodium salt) for all animal species when used in water for drinking
View page or View pdf

EPI System: View
ClinicalTrials.gov:search
Daily Med:search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):130-40-5
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :656596
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:1
sodium [(2S,3R,4R)-5-(7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10-yl)-2,3,4-trihydroxypentyl] hydrogen phosphate
Chemidplus:0000130405
 
References:
 sodium [(2S,3R,4R)-5-(7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10-yl)-2,3,4-trihydroxypentyl] hydrogen phosphate
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:130-40-5
Pubchem (cid):656596
Pubchem (sid):134973046
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
HMDB (The Human Metabolome Database):Search
FooDB:FDB010176
Export Tariff Code:2936.23.0000
FDA Listing of Food Additive Status:View
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
 biological additives
 
Occurrence (nature, food, other):note
 found in nature
 
Synonyms:
 infuvite
 riboflavin 5'-(dihydrogen phosphate) monosodium salt
 riboflavin 5'-(dihydrogen phosphate) sodium salt (1:1)
 riboflavin 5'-(dihydrogen phosphate), monosodium salt
 riboflavin 5'-(sodium hydrogen phosphate)
 riboflavin monophosphate monosodium salt
 riboflavin-5-phosphate sodium
 riboflavin-5'-phosphate sodium
 riboflavine phosphate sodium
 sodium [(2S,3R,4R)-5-(7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10-yl)-2,3,4-trihydroxypentyl] hydrogen phosphate
 sodium 5-deoxy-5-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2h)-yl)-1-o-(hydroxyphosphinato)-d-ribitol
 sodium riboflavin 5'-phosphate
 sodium riboflavin phosphate
 

Articles:

PubMed:A thixotropic supramolecular hydrogel of adenine and riboflavin-5'-phosphate sodium salt showing enhanced fluorescence properties.
PubMed:Matrix tablets based on a carrageenan with the modified-release of sodium riboflavin 5'-phosphate.
PubMed:[Ion-pair HPLC analysis of B vitamins in syrup products in Indonesia].
PubMed:Modified-release capsules containing sodium riboflavin 5'-phosphate.
PubMed:Tailored beads made of dissolved cellulose--investigation of their drug release properties.
PubMed:A novel riboflavin gastro-mucoadhesive delivery system based on ion-exchange fiber.
PubMed:Simultaneous determination of some water-soluble vitamins and preservatives in multivitamin syrup by validated stability-indicating high-performance liquid chromatography method.
PubMed:The simultaneous assay of riboflavin 5-phosphate sodium and other water-soluble vitamins in liquid multivitamin formulations by liquid chromatograph.
PubMed:Vitamin stability in a TPN mixture stored in an EVA plastic bag.
PubMed:[Resorption of cocarboxylase, riboflavin-5'-phosphate sodium and vitamin A in the colon].
 
Notes:
a coenzyme for a number of oxidative enzymes including nadh dehydrogenase. it is the principal form in which riboflavin is found in cells and tissues. nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. the richest natural source is yeast. it occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms in tissues and cells are as flavin mononucleotide and flavin-adenine dinucleotide. Used as a food additive [EAFUS]
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