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Category:cosmetic ingredient for skin conditioning
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Flash Point: | 32.00 °F. TCC ( 0.00 °C. ) (est)
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| Soluble in: |
| | water, 215.2 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
intraperitoneal-mouse LD50 36 mg/kg
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
BEHAVIORAL: EXCITEMENT
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Eisei Shikenjo Hokoku. Bulletin of the Institute of Hygienic Sciences. Vol. (103), Pg. 29, 1985.
intravenous-mouse LD50 107 mg/kg
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 90, Pg. 18, 1952.
oral-mouse LD50 1050 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE
GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH
Eisei Shikenjo Hokoku. Bulletin of the Institute of Hygienic Sciences. Vol. (103), Pg. 29, 1985.
intravenous-rabbit LDLo 15 mg/kg
BLOOD: OTHER CHANGES
LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA
CARDIAC: OTHER CHANGES
Zeitschrift fuer die Gesamte Experimentelle Medizin. Vol. 52, Pg. 779, 1926.
intraperitoneal-rat LD50 123 mg/kg
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
BEHAVIORAL: ATAXIA
BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
Oyo Yakuri. Pharmacometrics. Vol. 3, Pg. 45, 1969.
intravenous-rat LD50 150 mg/kg
Arzneimittel-Forschung. Drug Research. Vol. 20, Pg. 323, 1970.
oral-rat LD50 1370 mg/kg
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
BEHAVIORAL: ATAXIA
Oyo Yakuri. Pharmacometrics. Vol. 3, Pg. 45, 1969.
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| Dermal Toxicity: |
subcutaneous-mouse LD50 815 mg/kg
BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
BEHAVIORAL: ATAXIA
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Oyo Yakuri. Pharmacometrics. Vol. 3, Pg. 45, 1969.
subcutaneous-rat LD50 2430 mg/kg
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
BEHAVIORAL: ATAXIA
BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
Oyo Yakuri. Pharmacometrics. Vol. 3, Pg. 45, 1969.
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | cosmetic ingredient for skin conditioning |
| Recommendation for sodium deoxycholate usage levels up to: | | | not for fragrance use.
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| |
| Recommendation for sodium deoxycholate flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | deoxycholate sodium | | | deoxycholic acid, sodium salt | | | desoxycholate sodium | | | desoxycholic acid sodium salt | | (4R)-4-((1S,2S,11S,16S,5R,7R,10R,14R,15R)-5,16- | dihydroxy-2,15-dimethyltetracyc lo[8.7.0.0<2,7>.0<11,15>]heptadec-14-yl)pentanoic acid, sodium salt | | (4R)-4-((1S,2S,11S,16S,5R,7R,10R,14R,15R)-5,16- | dihydroxy-2,15-dimethyltetracyclo[8.7.0.0<2,7>.0<11,15>]heptadec-14-yl)pentanoic acid, sodium salt | | | sodium (4R)-4-[(3R,5R,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate | | | sodium 7-deoxycholate | | | sodium deoxycholic acid | | | sodium desoxycholate | | | sodiumdeoxycholate |
Articles:
| PubMed:Efficient transformation of Rhizopus delemar by electroporation of germinated spores. |
| PubMed:Use of sodium lauroyl sarcosinate (sarkosyl) in viable real-time PCR for enumeration of Escherichia coli. |
| PubMed:Toxicokinetic and mechanistic basis for the safety and tolerability of liposomal amphotericin B. |
| PubMed:A novel immunoproteomics method for identifying in vivo-induced Campylobacter jejuni antigens using pre-adsorbed sera from infected patients. |
| PubMed:Effects of microwave (2.45 GHz) irradiation on some biological characters of Salmonella typhimurium. |
| PubMed:Global transcriptional and phenotypic analyses of Escherichia coli O157:H7 strain Xuzhou21 and its pO157_Sal cured mutant. |
| PubMed:Study on interaction of bile salts with curcumin and curcumin embedded in dipalmitoyl-sn-glycero-3-phosphocholine liposome. |
| PubMed:Enzymatic synthesis of phosphatidylserine using bile salt mixed micelles. |
| PubMed:Resistance to bile salts and sodium deoxycholate in macrolide- and fluoroquinolone-susceptible and resistant Campylobacter jejuni and Campylobacter coli strains. |
| PubMed:Effects of efflux-pump inducers and genetic variation of the multidrug transporter cmeB in biocide resistance of Campylobacter jejuni and Campylobacter coli. |
| PubMed:Role of anionic charges of periplasmic glucans of Shigella flexneri in overcoming detergent stress. |
| PubMed:Cj1136 is required for lipooligosaccharide biosynthesis, hyperinvasion, and chick colonization by Campylobacter jejuni. |
| PubMed:Role of anionic charges of osmoregulated periplasmic glucans of Salmonella enterica serovar Typhimurium SL1344 in mice virulence. |
| PubMed:In vitro binding capacity of bile acids by defatted corn protein hydrolysate. |
| PubMed:Evaluation of a new enrichment broth for detection of Cronobacter spp. in powdered infant formula. |
| PubMed:Separation of dipeptides with two chiral centers using 2-hydroxypropyl-beta-CD-modified MEKC. |
| PubMed:Arcobacter trophiarum sp. nov., isolated from fattening pigs. |
| PubMed:Evaluation of Mycoplasma inactivation during production of biologics: egg-based viral vaccines as a model. |
| PubMed:Probiotic properties of yeasts isolated from chicken feces and kefirs. |
| PubMed:Discrimination of viable and dead Vibrio vulnificus after refrigerated and frozen storage using EMA, sodium deoxycholate and real-time PCR. |
| PubMed:Crab digestive phospholipase: a new invertebrate member. |
| PubMed:Improving the enrichment procedure for Enterobacteriaceae detection. |
| PubMed:Effect of putative efflux pump inhibitors and inducers on the antimicrobial susceptibility of Campylobacter jejuni and Campylobacter coli. |
| PubMed:Transport of Val-Leu-Pro-Val-Pro in human intestinal epithelial (Caco-2) cell monolayers. |
| PubMed:Culture of Campylobacter jejuni with sodium deoxycholate induces virulence gene expression. |
| PubMed:Virulence properties of Campylobacter jejuni isolates of poultry and human origin. |
| PubMed:Direct and rapid discrimination of aflatoxigenic strains based on fibre-optic room temperature phosphorescence detection. |
| PubMed:Modification of milk and whey surface properties by enzymatic hydrolysis of milk phospholipids. |
| PubMed:Study of a room temperature phosphorescence phenomenon to allow the detection of aflatoxigenic strains in culture media. |
| PubMed:In situ and in vivo efficacy of peroral absorption enhancers in rats and correlation to in vitro mechanistic studies. |
| PubMed:Purification and characterization of a fructosyltransferase from onion bulbs and its key role in the synthesis of fructo-oligosaccharides in vivo. |
| PubMed:A new micellar electrokinetic capillary chromatography method for separation of the components of the aminoglycoside antibiotics. |
| PubMed:Growth of autobioluminescent Campylobacter jejuni in response to various environmental conditions. |
| PubMed:Development of a method for direct visual determination of aflatoxin production by colonies of the Aspergillus flavus group. |
| PubMed:Comparison of recovery of airborne microorganisms in a dairy cattle facility using selective agar and thin agar layer resuscitation media. |
| PubMed:Improvements in the measurement of stool decay-accelerating factor in the detection of colorectal cancer. |
| PubMed:Biosynthetic requirements for the repair of membrane damage in pressure-treated Escherichia coli. |
| PubMed:Survival of Campylobacter jejuni during stationary phase: evidence for the absence of a phenotypic stationary-phase response. |
| PubMed:Cholesterol solubilization in aqueous micellar solutions of quillaja saponin, bile salts, or nonionic surfactants. |
| PubMed:Determination of biogenic amines in fish implicated in food poisoning by micellar electrokinetic capillary chromatography. |
| PubMed:Simultaneous determination of sweeteners and preservatives in preserved fruits by micellar electrokinetic capillary chromatography. |
| PubMed:Antitumorigenic effects of several food proteins in a rat model with colon cancer and their reverse correlation with plasma bile acid concentration. |
| PubMed:Simultaneous determination of antioxidants, preservatives and sweeteners permitted as additives in food by mixed micellar electrokinetic chromatography. |
| PubMed:A food-grade process for isolation and partial purification of bacteriocins of lactic acid bacteria that uses diatomite calcium silicate. |
| PubMed:Isolation of Campylobacter spp. from slaughtered cattle and swine on blood-free selective medium. |
| PubMed:Evaluation of cell death in EBV-transformed lymphocytes using agarose gel electrophoresis, light microscopy and electron microscopy. I. Induction of classic apoptosis by the bile salt, sodium deoxycholate. |
| PubMed:Micellar electrokinetic capillary chromatographic determination of artificial sweeteners in low-Joule soft drinks and other foods. |
| PubMed:Effects of rat bile-pancreatic juice on Fe2+ induced peroxidation of phospholipids. |
| PubMed:Use of inexpensive O antisera as the detecting antibodies for Salmonella antigens in the polymyxin-cloth enzyme immunoassay. |
| PubMed:[Features of Vibrio cholerae 0:1 El Tor, Inaba serotype, isolated during the cholera epidemic in Cartagena (Colombia)]. |
| PubMed:Evaluation of Chemicals for Restricting Colony Spreading by a Xerophilic Mold, Eurotium amstelodami, on Dichloran-18% Glycerol Agar. |
| PubMed:Distribution of 5'-nucleotidase in muscle of some marine fishes. |
| PubMed:Different forms of alkaline phosphatase in adult rat femur. Effect of a vitamin D3-deficient diet and of a sorbitol-enriched diet. |
| PubMed:Cytochrome b5/cytochrome b5 reductase complex in rat liver microsomes has NADH-linked aquacobalamin reductase activity. |
| PubMed:Purification of rough-type lipopolysaccharides of Neisseria meningitidis from cells and outer membrane vesicles in spent media. |
| PubMed:Pathogenic Escherichia coli O157:H7 and their detection. |
| PubMed:A p-nitrophenyl phosphorylcholine phosphodiesterase from mouse brain. |
| PubMed:The action of sodium deoxycholate on Escherichia coli. |
| PubMed:Ornithine decarboxylase induction in rat colon: synergistic effects of intrarectal instillation of sodium deoxycholate and starvation-refeeding. |
| PubMed:Immobilization of fumarase by entrapment of rat liver mitochondria in polyacrylamide gel using gamma rays. |
| PubMed:Fermentation by the human large intestine microbial community in an in vitro semicontinuous culture system. |
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3D/inchi