Category:herbicides / pesticides
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Appearance: | orange crystalline solid (est) |
Assay: | 95.00 to 100.00
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Food Chemicals Codex Listed: | No |
Melting Point: | 84.00 °C. @ 760.00 mm Hg
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Boiling Point: | 358.20 °C. @ 760.00 mm Hg
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Vapor Pressure: | 2.000000 mmHg @ 25.00 °C. (est) |
Flash Point: | 370.00 °F. TCC ( 187.90 °C. ) (est)
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logP (o/w): | 4.730 |
Soluble in: |
| water, 0.116 mg/L @ 25 °C (exp) | | water, 0.1958 mg/L @ 25 °C (est) |
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
oral-dog LD50 > 5 mg/kg Pesticide Manual. Vol. 9, Pg. 643, 1991.
oral-rat LD50 5000 mg/kg "Agricultural Chemicals," Thomson, W.T., 4 vols., Fresno, CA, Thomson Publications, 1976/77 revisionVol. 2, Pg. 201, 1977.
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Dermal Toxicity: |
skin-rabbit LD50 > 10000 mg/kg Pesticide Manual. Vol. 9, Pg. 643, 1991.
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Category: | herbicides / pesticides |
Recommendation for oxyfluorfen usage levels up to: | | not for fragrance use.
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Recommendation for oxyfluorfen flavor usage levels up to: |
| not for flavor use.
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Safety References:
European Food Safety Authority (EFSA) reference(s):
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Outcome of the consultation with Member States, the applicant and EFSA on the pesticide risk assessment of confirmatory data for the active substance oxyfluorfen View page or View pdf
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Retrospective analysis of the immunotoxic effects of plant protection products as reported in the Draft Assessment Reports for their peer review at EU level View page or View pdf
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Peer review of the pesticide risk assessment for the active substance oxyfluorfen in light of confirmatory data submitted View page or View pdf
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Protocol for the evaluation of data concerning the necessity of the application of herbicide active substances to control a serious danger to plant health which cannot be contained by other available means, including non-chemical methods View page or View pdf
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Review of the existing maximum residue levels for oxyfluorfen according to Article 12 of Regulation (EC) No 396/2005 View page or View pdf
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EPI System: View |
EPA-Iris:IRIS |
AIDS Citations:Search |
Cancer Citations:Search |
Toxicology Citations:Search |
EPA ACToR:Toxicology Data |
EPA Substance Registry Services (SRS):Registry |
Laboratory Chemical Safety Summary :39327 |
National Institute of Allergy and Infectious Diseases:Data |
WGK Germany:2 |
2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene |
Chemidplus:0042874033 |
EPA/NOAA CAMEO:hazardous materials |
RTECS:KN6900000 for cas# 42874-03-3 |
References:
| 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene |
NIST Chemistry WebBook: | Search Inchi |
Pubchem (cid): | 39327 |
Pubchem (sid): | 135000601 |
Other Information:
(IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
Videos: | The Periodic Table of Videos |
tgsc: | Atomic Weights use for this web site |
(IUPAC): | Periodic Table of the Elements |
CHEBI: | View |
CHEMBL: | View |
KEGG (GenomeNet): | C18881 |
HMDB (The Human Metabolome Database): | Search |
ChemSpider: | View |
Wikipedia: | View |
Formulations/Preparations: •chief 3sc herbicide active ingredient 14.2% glyphosate, isopropylamine salt, 21.1% oxyfluorfen
•double o g-pro active ingredient 1.0% oryzalin, 2.0% oxyfluorfen
•end zone herbicide active ingredient 22.2% oxyfluorfen
•galigan 2e active ingredient 22.2% oxyfluorfen
•galigan oxyfluorfen technical active ingredient 97.4% oxyfluorfen
•goal technical herbicide active ingredient 99.0% oxyfluorfen
•goal 2xl herbicide active ingredient 22.3% oxyfluorfen
•goaltender active ingredient 41.0% oxyfluorfen
•harrell's granular herbicide 75 active ingredient 3.0% trifluralin, 2.0% oxyfluorfen
•harrell's granular herbicide 63 active ingredient 2.0% oxyfluorfen
•kleenup super edger active ingredient 0.25% glyphosate, isopropylamine salt, 0.25% oxyfluorfen
•nations ag ii, llc oxyfluorfen 2 herbicide active ingredient 23.0% oxyfluorfen
•ornamental herbicide ii active ingredient 1.0% pendimethalin, 2.0% oxyfluorfen
•ortho fence & grass edger formula ii active ingredient 0.25% glyphosate, isopropylamine salt, 0.25% oxyfluorfen
•ortho season-long grass & weed killer active ingredient 0.1% diquat dibromide, 1.5% oxyfluorfen, 8.0% glyphosate
•oxyfluorfen tgai active ingredient 97.0% oxyfluorfen
•oxyfluorfen 2ec active ingredient 22.3% oxyfluorfen
•rawhide 4f herbicide active ingredient 20.3% glyphosate, isopropylamine salt, 20.3% oxyfluorfen
•regal o-o herbicide active ingredient 1.0% oxadiazon, 2.0% oxyfluorfen
•rout ornamental herbicide active ingredient 1.0% oryzalin, 2.0% oxyfluorfen
•showcase active ingredient 2.0% trifluralin, 0.25% oxyfluorfen, 0.25% isoxaben
•triox vegetation killer formula ii active ingredient 0.7% oxyfluorfen, 0.08% imazapyr, isopropylamine salt
•two ox e-pro herbicide active ingredient 1.0% oxadiazon, 2.0% oxyfluorfen
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Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| benzene, 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)- (9CI) | 2- | chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene | 2- | chloro-1-(3-ethoxy-4-nitrophenoxy)-4-trifluoromethylbenzene | 2- | chloro-alpha,alpha,alpha-trifluoro-p-tolyl-3-ethoxy-4-nitrophenyl ether | | ether, 2-chloro-alpha,alpha,alpha-trifluoro-p-tolyl 3-ethoxy-4-nitrophenyl | | galigan | | goldate | | hada F | | koltar | | oxyfluorfene |
Articles:
PubMed:Behaviour of oxyfluorfen in soils amended with edaphic biostimulants/biofertilizers obtained from sewage sludge and chicken feathers. Effects on soil biological properties. |
PubMed:Evaluation of three herbicide resistance genes for use in genetic transformations and for potential crop protection in algae production. |
PubMed:Behavior of oxyfluorfen in soils amended with different sources of organic matter. Effects on soil biology. |
PubMed:Monitoring of selected priority and emerging contaminants in the Guadalquivir River and other related surface waters in the province of JaƩn, South East Spain. |
PubMed:Contaminants of legacy and emerging concern in largescale suckers (Catostomus macrocheilus) and the foodweb in the lower Columbia River, Oregon and Washington, USA. |
PubMed:Community air monitoring for pesticides-part 2: multiresidue determination of pesticides in air by gas chromatography, gas chromatography-mass spectrometry, and liquid chromatography-mass spectrometry. |
PubMed:Community air monitoring for pesticides. Part 3: using health-based screening levels to evaluate results collected for a year. |
PubMed:Persistence of oxyfluorfen in soil, runoff water, sediment and plants of a sunflower cultivation. |
PubMed:Hypospadias and residential proximity to pesticide applications. |
PubMed:Field dissipation of oxyfluorfen in onion and its dynamics in soil under Indian tropical conditions. |
PubMed:Photolysis of oxyfluorfen in aqueous methanol. |
PubMed:The use of antioxidant enzymes in freshwater biofilms: temporal variability vs. toxicological responses. |
PubMed:Identifying the cause of sediment toxicity in agricultural sediments: the role of pyrethroids and nine seldom-measured hydrophobic pesticides. |
PubMed:Assessment of possible carcinogenicity of oxyfluorfen to humans using mode of action analysis of rodent liver effects. |
PubMed:Light history modulates antioxidant and photosynthetic responses of biofilms to both natural (light) and chemical (herbicides) stressors. |
PubMed:Differential physiological and biochemical responses of two cyanobacteria Nostoc muscorum and Phormidium foveolarum against oxyfluorfen and UV-B radiation. |
PubMed:Toxicity of sediment-associated pesticides to Chironomus dilutus and Hyalella azteca. |
PubMed:Overexpression of a specific soybean GmGSTU4 isoenzyme improves diphenyl ether and chloroacetanilide herbicide tolerance of transgenic tobacco plants. |
PubMed:[Determination of biphenyl ether herbicides in water using HPLC with cloud-point extraction]. |
PubMed:Enhanced dissipation of oxyfluorfen, ethalfluralin, trifluralin, propyzamide, and pendimethalin in soil by solarization and biosolarization. |
PubMed:Development of a sample preparation method for the analysis of current-use pesticides in sediment using gas chromatography. |
PubMed:Pesticide extraction from table grapes and plums using ionic liquid based dispersive liquid-liquid microextraction. |
PubMed:Ionic liquid based dispersive liquid-liquid microextraction for the extraction of pesticides from bananas. |
PubMed:Pendimethalin and oxyfluorfen degradation under two irrigation conditions over four years application. |
PubMed:Persistence and bioaccumulation of oxyfluorfen residues in onion. |
PubMed:Micellar modified spectrophotometric determination of nitrobenzenes based upon reduction with tin(II), diazotisation and coupling with the Bratton-Marshall reagent. |
PubMed:Metabolism of nitrodiphenyl ether herbicides by dioxin-degrading bacterium Sphingomonas wittichii RW1. |
PubMed:Optimization of separation and detection conditions for the multiresidue analysis of pesticides in grapes by comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry. |
PubMed:Evaluation of six pesticides leaching indexes using field data of herbicide application in Casablanca Valley, Chile. |
PubMed:Determination of diphenylether herbicides in water samples by solid-phase microextraction coupled to liquid chromatography. |
PubMed:[Experimental study on oxyfluorfen technical herbicides induced mutagenicity]. |
PubMed:Effect of systemic herbicides on N2-fixing and phosphate solubilizing microorganisms in relation to availability of nitrogen and phosphorus in paddy soils of West Bengal. |
PubMed:[Determination of acetochlor and oxyfluorfen by capillary gas chromatography]. |
PubMed:Assessment of the plasma desorption time-of-flight mass spectrometry technique for pesticide adsorption and degradation on 'as-received' treated soil samples. |
PubMed:Herbicidal and antioxidant responses of transgenic rice overexpressing Myxococcus xanthus protoporphyrinogen oxidase. |
PubMed:Weed control and persistence of two oxyfluorfen formulations in olive groves under non tillage conditions. |
PubMed:Pesticide patch test series for the assessment of allergic contact dermatitis among banana plantation workers in panama. |
PubMed:Surface retention and photochemical reactivity of the diphenylether herbicide oxyfluorfen. |
PubMed:Oxyfluorfen toxic effect on S. obliquus evaluated by different photosynthetic and enzymatic biomarkers. |
PubMed:A point mutation of valine-311 to methionine in Bacillus subtilis protoporphyrinogen oxidase does not greatly increase resistance to the diphenyl ether herbicide oxyfluorfen. |
PubMed:Effect of the herbicides oxadiazon and oxyfluorfen on phosphates solubilizing microorganisms and their persistence in rice fields. |
PubMed:Dissipation of the herbicide oxyfluorfen in subtropical soils and its potential to contaminate groundwater. |
PubMed:Weed control in rose-scented geranium (Pelargonium spp). |
PubMed:Jasmonate is involved in the induction of tyrosine aminotransferase and tocopherol biosynthesis in Arabidopsis thaliana. |
PubMed:Degradation of oxyfluorfen by Azotobacter chroococcum (Beijerink). |
PubMed:Toxicological effects of the herbicide oxyfluorfen on acetylcholinesterase in two fish species: Oreochromis niloticus and Gambusia affinis. |
PubMed:Resistance of a soybean cell line to oxyfluorfen by overproduction of mitochondrial protoporphyrinogen oxidase. |
PubMed:Transgenic rice plants expressing a Bacillus subtilis protoporphyrinogen oxidase gene are resistant to diphenyl ether herbicide oxyfluorfen. |
PubMed:Laboratory study on leachability of five herbicides in South Australian soils. |
PubMed:Induction of hsp70 by the herbicide oxyfluorfen (Goal) in the Egyptian Nile fish, Oreochromis niloticus. |
PubMed:Herbicide residues in grapes and wine. |
PubMed:Herbicide-induced experimental variegate porphyria in mice: tissue porphyrinogen accumulation and response to porphyrogenic drugs. |
PubMed:Effects of a diphenyl-ether herbicide, oxyfluorfen, on human BFU-E/CFU-E development and haemoglobin synthesis. |
PubMed:Protoporphyrinogen oxidase: high affinity tetrahydrophthalimide radioligand for the inhibitor/herbicide-binding site in mouse liver mitochondria. |
PubMed:Photoaffinity labeling of protoporphyrinogen oxidase, the molecular target of diphenylether-type herbicides. |
PubMed:Effect of the protoporphyrinogen oxidase-inhibiting herbicide fomesafen on liver uroporphyrin and heptacarboxylic porphyrin in two mouse strains. |
PubMed:Effect of diphenyl ether herbicides and oxadiazon on porphyrin biosynthesis in mouse liver, rat primary hepatocyte culture and HepG2 cells. |
PubMed:Developmental toxicity of diphenyl ether herbicides in nestling American kestrels. |
PubMed:Determination of oxyfluorfen herbicide and oxyfluorfen amine residues in garbanzo beans by liquid chromatography. |
PubMed:Disappearance of oxyfluorfen (goal) from onions and organic soils. |
PubMed:The generation of singlet oxygen (o(2)) by the nitrodiphenyl ether herbicide oxyfluorfen is independent of photosynthesis. |
PubMed:Photosynthesis involvement in the mechanism of action of diphenyl ether herbicides. |
PubMed:Evidence from studies with acifluorfen for participation of a flavin-cytochrome complex in blue light photoreception for phototropism of oat coleoptiles. |
PubMed:Fate of 2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl) benzene (oxyfluorofen) in rats. |
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