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Category:herbicides / pesticides
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | white solid (est) |
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Melting Point: | 155.00 °C. @ 760.00 mm Hg
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| Boiling Point: | 340.90 °C. @ 760.00 mm Hg (est)
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| Flash Point: | 320.00 °F. TCC ( 160.00 °C. ) (est)
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| logP (o/w): | 3.430 |
| Soluble in: |
| | water, 15 mg/L @ 25 °C (exp) | | | water, 25.74 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-dog LD50 10000 mg/kg
Farm Chemicals Handbook. Vol. -, Pg. C177, 1991.
oral-duck LD50 > 14000 mg/kg
Defense des Vegetaux. Vol. 26, Pg. 192, 1972.
oral-rat LD50 3350 mg/kg
Defense des Vegetaux. Vol. 26, Pg. 192, 1972.
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| Dermal Toxicity: |
skin-rabbit LDLo > 3160 mg/kg
Defense des Vegetaux. Vol. 26, Pg. 192, 1972.
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | herbicides / pesticides |
| Recommendation for propyzamide usage levels up to: | | | not for fragrance use.
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| |
| Recommendation for propyzamide flavor usage levels up to: |
| | not for flavor use.
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Safety References:
European Food Safety Authority (EFSA) reference(s):
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Reasoned opinion on the modification of the existing MRLs for propyzamide in leaves, flowers and roots of herbal infusions
View page or View pdf
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Outcome of the consultation with Member States, the applicant and EFSA on the pesticide risk assessment for propyzamide in light of confirmatory data
View page or View pdf
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| EPI System: View |
| EPA-Iris:IRIS |
| Chemical Carcinogenesis Research Information System:Search |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| Carcinogenic Potency Database:Search |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :32154 |
| National Institute of Allergy and Infectious Diseases:Data |
| WGK Germany:3 |
| 3,5-dichloro-N-(2-methylbut-3-yn-2-yl)benzamide |
| Chemidplus:0023950585 |
| EPA/NOAA CAMEO:hazardous materials |
| RTECS:CV3460000 for cas# 23950-58-5 |
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | benzamide, 3,5-dichloro-N-(1,1-dimethyl-2-propyn-1-yl)- | | | benzamide, 3,5-dichloro-N-(1,1-dimethyl-2-propynyl)- | | | clanex | | 3,5- | dichlor-N-(2-methyl-3-butin-2-yl)benzamid | | 3,5- | dichlor-N-(2-methylbut-3-in-2-yl)benzamid | | 3,5- | dichloro-N-(1,1-dimethyl-2-propynyl) benzamide | | 3,5- | dichloro-n-(1,1-dimethyl-2-propynyl)benzamide | | 3,5- | dichloro-N-(1,1-dimethyl-prop-2-ynyl)-benzamide | | 3,5- | dichloro-N-(1,1-dimethylprop-2-yn-1-yl)benzamide | | 3,5- | dichloro-N-(1,1-dimethylprop-2-ynyl)benzamide | | 3,5- | dichloro-N-(1,1-dimethylpropynyl)benzamide | | 3,5- | dichloro-N-(2-methyl-3-butyn-2-yl)benzamide | | 3,5- | dichloro-N-(2-methylbut-3-yn-2-yl)benzamide | | 3,5- | dichloro(N-1,1-dimethyl-2-propynyl)benzamide | | (3,5- | dichlorophenyl)-N-(1,1-dimethylprop-2-ynyl)carboxamide | | | kerb 50W | | | pronamid | | | pronamide | | | propisamide | | | propizamide |
Articles:
| PubMed:Aphidicolin-Induced Nuclear Elongation in Tobacco BY-2 cells. |
| PubMed:Community air monitoring for pesticides-part 2: multiresidue determination of pesticides in air by gas chromatography, gas chromatography-mass spectrometry, and liquid chromatography-mass spectrometry. |
| PubMed:Phosphatidic acid integrates calcium signaling and microtubule dynamics into regulating ABA-induced stomatal closure in Arabidopsis. |
| PubMed:Influence of an intensive agricultural drainage basin on the seasonal distribution of organic pollutants in seawater from a Mediterranean coastal lagoon (Mar Menor, SE Spain). |
| PubMed:An atypical tubulin kinase mediates stress-induced microtubule depolymerization in Arabidopsis. |
| PubMed:Modulation of root-skewing responses by KNAT1 in Arabidopsis thaliana. |
| PubMed:Environmental fate of fungicides and other current-use pesticides in a central California estuary. |
| PubMed:Hazard-ranking of agricultural pesticides for chronic health effects in Yuma County, Arizona. |
| PubMed:Mechanism of microtubule array expansion in the cytokinetic phragmoplast. |
| PubMed:α-tubulin is rapidly phosphorylated in response to hyperosmotic stress in rice and Arabidopsis. |
| PubMed:Pesticide leaching from two Swedish topsoils of contrasting texture amended with biochar. |
| PubMed:Seasonal input of regulated and emerging organic pollutants through surface watercourses to a Mediterranean coastal lagoon. |
| PubMed:Predicting rapid herbicide leaching to surface waters from an artificially drained headwater catchment using a one dimensional two-domain model coupled with a simple groundwater model. |
| PubMed:Micronucleation by mitosis inhibitors in developing microspores of Spathiphyllum wallisii Regel. |
| PubMed:NIMA-related kinases regulate directional cell growth and organ development through microtubule function in Arabidopsis thaliana. |
| PubMed:Measurement and conceptual modelling of herbicide transport to field drains in a heavy clay soil with implications for catchment-scale water quality management. |
| PubMed:Acquisition of embryogenic competency does not require cell division in carrot somatic cell. |
| PubMed:Lipid body biogenesis and the role of microtubules in lipid synthesis in Ornithogalum umbellatum lipotubuloids. |
| PubMed:Salt stress-induced disassembly of Arabidopsis cortical microtubule arrays involves 26S proteasome-dependent degradation of SPIRAL1. |
| PubMed:NIMA-related kinases 6, 4, and 5 interact with each other to regulate microtubule organization during epidermal cell expansion in Arabidopsis thaliana. |
| PubMed:Use of farming and agro-industrial wastes as versatile barriers in reducing pesticide leaching through soil columns. |
| PubMed:Tobacco microtubule-associated protein, MAP65-1c, bundles and stabilizes microtubules. |
| PubMed:Blockage of mitosis in maize root tips using colchicine-alternatives. |
| PubMed:Enhanced dissipation of oxyfluorfen, ethalfluralin, trifluralin, propyzamide, and pendimethalin in soil by solarization and biosolarization. |
| PubMed:Actin reorganization underlies phototropin-dependent positioning of nuclei in Arabidopsis leaf cells. |
| PubMed:Predictive modeling of a mixture of thyroid hormone disrupting chemicals that affect production and clearance of thyroxine. |
| PubMed:Photocatalytic degradation of eight pesticides in leaching water by use of ZnO under natural sunlight. |
| PubMed:Arabidopsis mitogen-activated protein kinase MPK18 mediates cortical microtubule functions in plant cells. |
| PubMed:Arabidopsis microtubule-associated protein AtMAP65-2 acts as a microtubule stabilizer. |
| PubMed:Salt tolerance requires cortical microtubule reorganization in Arabidopsis. |
| PubMed:Excessive expression of the plant kinesin TBK5 converts cortical and perinuclear microtubules into a radial array emanating from a single focus. |
| PubMed:Cell cycle synchronization of tobacco BY-2 cells. |
| PubMed:Molecular cloning and gene expression of a fibrillarin homolog of tobacco BY-2 cells. |
| PubMed:Change in the actin cytoskeleton during seismonastic movement of Mimosa pudica. |
| PubMed:The WAG1 and WAG2 protein kinases negatively regulate root waving in Arabidopsis. |
| PubMed:Narrowing of the preprophase microtubule band is not required for cell division plane determination in cultured plant cells. |
| PubMed:Isolation of a protein interacting with Vfphot1a in guard cells of Vicia faba. |
| PubMed:Loss-of-function mutations of ROOT HAIR DEFECTIVE3 suppress root waving, skewing, and epidermal cell file rotation in Arabidopsis. |
| PubMed:Localization of actin filaments on mitotic apparatus in tobacco BY-2 cells. |
| PubMed:Does the effect of herbicide pulse exposure on aquatic plants depend on Kow or mode of action? |
| PubMed:In vivo dynamics and differential microtubule-binding activities of MAP65 proteins. |
| PubMed:Low concentrations of propyzamide and oryzalin alter microtubule dynamics in Arabidopsis epidermal cells. |
| PubMed:Complete mineralization of propyzamide in aqueous solution containing TiO2 particles and H2O2 by the simultaneous irradiation of light and ultrasonic waves. |
| PubMed:Sonochemical preparation of composite nanoparticles of Au/gamma-Fe2O3 and magnetic separation of glutathione. |
| PubMed:A semidominant mutation in an Arabidopsis mitogen-activated protein kinase phosphatase-like gene compromises cortical microtubule organization. |
| PubMed:The Arabidopsis sku6/spiral1 gene encodes a plus end-localized microtubule-interacting protein involved in directional cell expansion. |
| PubMed:Microtubules and microfilaments coordinate to direct a fountain streaming pattern in elongating conifer pollen tube tips. |
| PubMed:Is microtubule disassembly a trigger for cold acclimation? |
| PubMed:Involvement of microtubules in rhizoid differentiation of Spirogyra species. |
| PubMed:Visualization of peroxisomes in living plant cells reveals acto-myosin-dependent cytoplasmic streaming and peroxisome budding. |
| PubMed:DNA catenations that link sister chromatids until the onset of anaphase are maintained by a checkpoint mechanism. |
| PubMed:Simultaneous visualization of peroxisomes and cytoskeletal elements reveals actin and not microtubule-based peroxisome motility in plants. |
| PubMed:Sub-cellular localisation of GFP-tagged tobacco mitotic cyclins during the cell cycle and after spindle checkpoint activation. |
| PubMed:Preparative-scale synthesis of two metabolites isolated from soil treated with zoxium fungicide and kerb herbicide. |
| PubMed:Involvement of cortical microtubules in plastic extension regulated by gibberellin in Lemna minor root. |
| PubMed:The role of microtubules in guard cell function. |
| PubMed:Ruminations regarding the design of small mixtures for biological testing. |
| PubMed:The SPIRAL genes are required for directional control of cell elongation in Aarabidopsis thaliana. |
| PubMed:Covalent binding of the benzamide RH-4032 to tubulin in suspension-cultured tobacco cells and its application in a cell-based competitive-binding assay. |
| PubMed:Simultaneous determination of acidic and non-acidic pesticides in natural waters by liquid chromatography-mass spectrometry. |
| PubMed:Screening of selected pesticides for inhibition of CYP19 aromatase activity in vitro. |
| PubMed:Soil dissipation of diuron, chlorotoluron, simazine, propyzamide, and diflufenican herbicides after repeated applications in fruit tree orchards. |
| PubMed:Microtubule stabilization leads to growth reorientation in Arabidopsis trichomes. |
| PubMed:Plant cell biology through the window of the highly synchronized tobacco BY-2 cell line. |
| PubMed:Indomethacin-induced G1/S phase arrest of the plant cell cycle. |
| PubMed:A low content in zeatin type cytokinins is not restrictive for the occurrence of G1/S transition in tobacco BY-2 cells. |
| PubMed:Dinitroaniline herbicide-resistant transgenic tobacco plants generated by co-overexpression of a mutant alpha-tubulin and a beta-tubulin. |
| PubMed:In situ synthesis of beta-glucan microfibrils on tobacco plasma membrane sheets. |
| PubMed:A cell cycle regulated MAP kinase with a possible role in cytokinesis in tobacco cells. |
| PubMed:Dynamic organization of microtubules in guard cells of Vicia faba L. with diurnal cycle. |
| PubMed:Ploidy of small individual embryo-like structures from maize anther cultures treated with chromosome doubling agents and calli derived from them. |
| PubMed:Monoclonal antibodies specific for ohmefentanyl. |
| PubMed:Ploidy variation of pronamide-treated maize calli during long term culture. |
| PubMed:The colR4 and colR15 beta-tubulin mutations in Chlamydomonas reinhardtii confer altered sensitivities to microtubule inhibitors and herbicides by enhancing microtubule stability. |
| PubMed:Capillary column gas chromatography with nitrogen-phosphorus detection for determination of nitrogen- and phosphorus-containing pesticides in finished drinking waters: collaborative study. |
| PubMed:The use of antimicrotubule herbicides for the production of doubled haploid plants from anther-derived maize callus. |
| PubMed:A Dinitroaniline-Resistant Mutant of Eleusine indica Exhibits Cross-Resistance and Supersensitivity to Antimicrotubule Herbicides and Drugs. |
| PubMed:Concentrations of the herbicides propyzamide, chlorpropham, and of their metabolites in soil and lettuce under field conditions. |
| PubMed:The role of necrosis in hepatocellular proliferation and liver tumors. |
| PubMed:Transplantation studies on induced and spontaneous nodules from B6C3F1 mouse liver. |
| PubMed:Applicability of a carbamate insecticide multiresidue method for determining additional types of pesticides in fruits and vegetables. |
| PubMed:[Effect of application of a herbicide propyzamide into the soil by study of mineralization of glucose 14C(U) and distribution of radioactivity in various fractions of the soil (laboratory and open field tests)]. |
| PubMed:Enzymatic alterations in mouse hepatic nodules induced by a chlorinated hydrocarbon pesticide. |
| PubMed:[Chromatographic determination of propisamide (kerba) in water, soil and plants]. |
| PubMed:Carcinogenicity of pronamide. |
| PubMed:Metabolism of the herbicide pronamide in soil. |
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3D/inchi