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acetaldehyde tetramer
metaldehyde (bsi:iso)

Supplier Sponsors

CAS Number: 108-62-3Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:203-745-1
FDA UNII: 4CI033VJYG
Nikkaji Web:J2.423F
XlogP3:1.10 (est)
Molecular Weight:176.21232000
Formula:C8 H16 O4
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:information only not used for fragrances or flavors
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Soluble in:
 water, 222 mg/L @ 20 °C (exp)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
Metaldehyde ≥97%
TCI AMERICA
For experimental / research use only.
Metaldehyde >97.0%(T)
sds
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-cat LD50 207 mg/kg
"Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 15, 1982.

oral-child LDLo 100 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
"Pflanzenschutz-und Schaedlingsbekaempfungsmittel: Abriss einer Toxikologie und Therapie von Vergiftungen," 2nd ed., Klimmer, O.R., Hattingen, Fed. Rep. Ger., Hundt-Verlag, 1971Vol. -, Pg. 158, 1971.

oral-dog LD50 600 mg/kg
Guide to the Chemicals Used in Crop Protection. Vol. 6, Pg. 331, 1973.

oral-guinea pig LD50 175 mg/kg
"Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 15, 1982.

oral-human LDLo 343 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 34, Pg. 1464, 1992.

unreported-mammal (species unspecified) LD50 600 mg/kg
"Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971Vol. -, Pg. 111, 1971.

oral-mouse LD50 200 mg/kg
"Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 15, 1982.

oral-rabbit LD50 290 mg/kg
"Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 15, 1982.

oral-rat LD50 227 mg/kg
"Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 15, 1982.

Dermal Toxicity:
skin-rat LD50 2275 mg/kg
"Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 15, 1982.

Inhalation Toxicity:
inhalation-mouse LC50 348 mg/m3/2H
"Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 15, 1982.

inhalation-rat LC50 203 mg/m3/4H
"Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 15, 1982.
 
Safety in Use Information:
Category:
information only not used for fragrances or flavors
Recommendation for acetaldehyde tetramer usage levels up to:
 not for fragrance use.
 
Recommendation for acetaldehyde tetramer flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :61021
National Institute of Allergy and Infectious Diseases:Data
2,4,6,8-tetramethyl-1,3,5,7-tetraoxocane
Chemidplus:0000108623
 
References:
 2,4,6,8-tetramethyl-1,3,5,7-tetraoxocane
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):61021
Pubchem (cas):108-62-3
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C18744
HMDB (The Human Metabolome Database):Search
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 caswell no. 548
 cekumeta
 corry's slug death
 metacetaldehyde (bsi:iso)
 metaldehyde (bsi:iso)
 metason
 slug-tox
2,4,6,8-tetramethyl-1,3,5,7-tetroxocane
R-2,C-4,C-6,C-8-tetramethyl-1,3,5,7-tetroxocane
 

Articles:

PubMed:Metaldehyde
PubMed:Ubiquity of microbial capacity to degrade metaldehyde in dissimilar agricultural, allotment and garden soils
PubMed:Fatal metaldehyde poisoning in a dog confirmed by gas chromatography
PubMed:Degradation of Metaldehyde in Aqueous Solution by Nano-Sized Photocatalysts and Granular Activated Carbon
PubMed:Metaldehyde Poisoning of Companion Animals: A Three-year Retrospective Study
PubMed:From full-scale biofilters to bioreactors: Engineering biological metaldehyde removal
PubMed:Isolation and characterization of metaldehyde-degrading bacteria from domestic soils
PubMed:The effects of metaldehyde on non-target aquatic macroinvertebrates: Integrating field and laboratory-based evidence
PubMed:Degradation of metaldehyde in water by nanoparticle catalysts and powdered activated carbon
PubMed:Metaldehyde exposures
PubMed:Achieving drinking water compliance levels for metaldehyde with an acclimated sand bioreactor
PubMed:Comparison of different monitoring methods for the measurement of metaldehyde in surface waters
PubMed:Metaldehyde toxicity: a review
PubMed:Self-poisoning with metaldehyde
PubMed:Modelling metaldehyde in catchments: a River Thames case-study
PubMed:Metaldehyde prediction by integrating existing water industry datasets with the soil and water assessment tool
PubMed:Metaldehyde poisoning
PubMed:Metaldehyde poisoning
PubMed:Measuring metaldehyde in surface waters in the UK using two monitoring approaches
PubMed:Reports of metaldehyde and iron phosphate exposures in animals and characterization of suspected iron toxicosis in dogs
PubMed:Retrospective evaluation of the use of hemodialysis in dogs with suspected metaldehyde poisoning (2012-2017): 11 cases
PubMed:An investigation of metaldehyde and acetaldehyde toxicities in dogs
PubMed:Metaldehyde poisoning
PubMed:Developmental toxicity of metaldehyde in the embryos of Lymnaea stagnalis (Gastropoda: Pulmonata) co-exposed to the synergist piperonyl butoxide
PubMed:TAML/H2O2 Oxidative Degradation of Metaldehyde: Pursuing Better Water Treatment for the Most Persistent Pollutants
PubMed:Modification of the existing maximum residue level for metaldehyde in leek
PubMed:Efficacy of a Novel Metaldehyde Application Method to Control the Brown Garden Snail, Cornu aspersum (Helicidae), in South Africa
PubMed:Dissipation, residues and risk assessment of metaldehyde and niclosamide ethanolamine in pakchoi after field application
PubMed:Metaldehyde poisoning of dogs
PubMed:Metaldehyde poisoning of dogs
PubMed:Metaldehyde removal from aqueous solution by adsorption and ion exchange mechanisms onto activated carbon and polymeric sorbents
PubMed:Conventional treatment of a metaldehyde-intoxicated cat with additional use of low-dose intravenous lipid emulsion
PubMed:Evaluation of the in vitro efficacy of hemodialysis, hemoperfusion, and the combined approach on the removal of metaldehyde from canine plasma
PubMed:Explaining the interactions between metaldehyde and acidic surface groups of activated carbon under different pH conditions
PubMed:Fragmentation patterns involving ammonium adduct fragment ions: A comparison of the determination of metaldehyde in human blood by HPLC-QqQ-MS/MS and UHPLC-Q-TOF-MS
PubMed:A new conceptual model of pesticide transfers from agricultural land to surface waters with a specific focus on metaldehyde
PubMed:Direct Analysis and Quantification of Metaldehyde in Water using Reactive Paper Spray Mass Spectrometry
PubMed:Metaldehyde poisoning in a dairy herd
PubMed:Calibration and field evaluation of the Chemcatcher? passive sampler for monitoring metaldehyde in surface water
PubMed:An improved method for measuring metaldehyde in surface water using liquid chromatography tandem mass spectrometry
PubMed:Super-refractory nonconvulsive status epilepticus due to self-poisoning with metaldehyde
PubMed:Residues and dissipation dynamics of molluscicide metaldehyde in cabbage and soil
PubMed:Adsorption effects of activated charcoal on metaldehyde toxicity in rats
PubMed:In vivo effects of metaldehyde on Pacific oyster, Crassostrea gigas: comparing hemocyte parameters in two oyster families
PubMed:Phenolic carbon tailored for the removal of polar organic contaminants from water: a solution to the metaldehyde problem?
PubMed:Metaldehyde toxicosis in ducklings
PubMed:Acute metaldehyde poisoning in Taiwan
PubMed:Integrated catchment management for reducing pesticide levels in water: Engaging with stakeholders in East Anglia to tackle metaldehyde
PubMed:[Effectiveness of snail control by immersion of molluscicides through tide diversion in marshlands: a field evaluation]
PubMed:Metaldehyde: pet poisonings
PubMed:Determination of metaldehyde in human serum by headspace solid-phase microextraction and gas chromatography-mass spectrometry
PubMed:Analysis of molluscicide metaldehyde in vegetables by dispersive solid-phase extraction and liquid chromatography-tandem mass spectrometry
PubMed:Suspected metaldehyde slug bait poisoning in dogs: a retrospective analysis of cases reported to the Veterinary Poisons Information Service
PubMed:Contact toxicity and biochemical impact of metaldehyde against the white garden snail Theba pisana (Mller, 1774)
PubMed:Arsenic and metaldehyde toxicosis in a beef herd
PubMed:The effects of repeated applications of the molluscicide metaldehyde and the biocontrol nematode Phasmarhabditis hermaphrodita on molluscs, earthworms, nematodes, acarids and collembolans: a two-year study
PubMed:Comparison of UV/H2O2 and UV/TiO2 for the degradation of metaldehyde: Kinetics and the impact of background organics
PubMed:Toxicoses of the Ruminant Nervous System
PubMed:Indoor poisoning of companion animals by chemicals
PubMed:[Toxicology of metaldehyde]
PubMed:The toxicity of the molluscicides metaldehyde and methiocarb to dogs
PubMed:Low pressure UV/H2O2 treatment for the degradation of the pesticides metaldehyde, clopyralid and mecoprop - Kinetics and reaction product formation
PubMed:Determination of metaldehyde in workroom air
PubMed:Anaesthetic control for metaldehyde poisoning
PubMed:An outbreak of metaldehyde poisoning in sheep
PubMed:Identification of environmental factors limiting plant uptake of metaldehyde seed treatments under field conditions
PubMed:Pesticide toxicosis in the horse
PubMed:Metaldehyde poisoning in horses
PubMed:Anaesthetic control for metaldehyde poisoning
PubMed:Fungal volatile organic compounds show promise as potent molluscicides
PubMed:Types of pesticides involved in domestic and wild animal poisoning in Italy
PubMed:Homogeneous Catalysis Under Ultradilute Conditions: TAML/NaClO Oxidation of Persistent Metaldehyde
PubMed:Phenobarbital-type P-450 inducers protect rats against metaldehyde toxicity
PubMed:Metaldehyde poisoning in three horses
PubMed:Metaldehyde poisoning from slug bait ingestion
PubMed:Clinical, neurological and clinicopathological signs, treatment and outcome of metaldehyde intoxication in 18 dogs
PubMed:Efficacy of chemical and biological slug control measures in response to watering and earthworms
PubMed:[Murder by metaldehyde poisoning]
PubMed:Long-term toxicity and reproduction studies with metaldehyde in rats
PubMed:Peroxidation and unsaturation coefficients as biomarkers of environmental micro-exposure to molluscicides in Helix pomatia L
PubMed:Zoonoses and other findings in hedgehogs (Erinaceus europaeus): a survey of mortality and review of the literature
PubMed:Local context and environment as risk factors for acute poisoning in animals in northwest Italy
PubMed:Environmental impact of two molluscicides: niclosamide and metaldehyde in a rice paddy ecosystem
PubMed:Inspective and toxicological survey of the poisoned baits and bites
PubMed:Miniaturized array gas membrane separation strategy for rapid analysis of complex samples by surface-enhanced Raman scattering
PubMed:Effects of season and sediment-water exchange processes on the partitioning of pesticides in the catchment environment: Implications for pesticides monitoring
PubMed:[Identification and determination of metaldehyde]
PubMed:Metaldehyde residues on and in citrus fruits after a soil broadcast of a granular formulation and after a spray application to citrus trees
PubMed:Pesticide incidence in poisoned baits: A 10-year report
PubMed:Pesticide contact dermatitis in agricultural workers of Himachal Pradesh (India)
PubMed:Geographical characteristics influencing the risk of poisoning in pet dogs: Results of a large population-based epidemiological study in Italy
PubMed:Epileptic brain damage in dogs and cats: myth or reality?
PubMed:Determination of metaldehyde in suspected cases of animal poisoning using gas chromatography-ion trap mass spectrometry
PubMed:Disinfection by-product formation during UV/Chlorine treatment of pesticides in a novel UV-LED reactor at 285˙nm and the mitigation impact of GAC treatment
PubMed:Letter: Blindness associated with metaldehyde poisoning
PubMed:Pharmacological aspects of metaldehyde poisoning in mice
PubMed:Practical toxicologic diagnosis
PubMed:[Toxicity of metaldehyde for the dog. Determination of DL50]
PubMed:The impact of background organic matter and alkalinity on the degradation of the pesticide metaldehyde by two advanced oxidation processes: UV/H?O? and UV/TiO?
PubMed:Researches and applications of the ultrasonic emulsifications and dispersions
PubMed:Metaldehyde poisoning in cattle
PubMed:Metaldehyde and paraquat poisoning
PubMed:[Metaldehyde against terrestrial molluscs]
PubMed:Three cases of metaldehyde poisoning in cattle
PubMed:[Effect and cost-effectiveness of three commonly used molluscicides in largescale field application]
PubMed:Analysis of metaldehyde in cow blood samples
PubMed:Suspected poisoning of domestic animals by pesticides
PubMed:Gas chromatographic analysis of metaldehyde in urine and plasma
PubMed:Pathogenicity of wild and commercial Phasmarhabditis hermaphrodita exposed to the pestiferous slug Deroceras invadens
PubMed:Treatment of metaldehyde poisoning in dogs with megadoses of acepromazine maleate
PubMed:Canine status epilepticus due to acute intoxication
PubMed:[Metaldehyde poisoning on a bivouac]
PubMed:Metaldehyde poisoning in the dog
PubMed:Persistence of metaldehyde during acute molluscicide poisoning
PubMed:[Evaluation on molluscicidal effect of suspension concentrate of metaldehyde and niclosamide]
PubMed:Apropos: critical analysis of molluscicide application in schistosomiasis control programs in Brazil
PubMed:Seed dressings to control slug damage in oilseed rape
PubMed:Metaldehyde poisoning in farm animals
PubMed:A multiresidue screen for the analysis of toxicants in bovine rumen contents
PubMed:[Molluscicidal effect and cost-effectiveness of suspension concentrate of metaldehyde and niclosamide in the field in Honghu City]
PubMed:[Pesticide poisoning]
PubMed:Metaldehyde poisoning in a dairy herd
PubMed:[Molluscicidal effect of suspension concentrate of metaldehyde and niclosamide in fields of mountainous areas in Yunnan Province]
PubMed:Differential susceptibility of species of slugs to metaldehyde/bran and to methiocarb baits
PubMed:Gas chromatographic method for the analysis of metaldehyde in crop tissue
PubMed:Susceptibility of the Giant African snail (Achatina fulica) exposed to the gastropod parasitic nematode Phasmarhabditis hermaphrodita
PubMed:Biochemical studies on the terrestrial snail, Eubania vermiculata (Mller) treated with some pesticides
PubMed:Molluscicide baits impair the life traits of Folsomia candida (Collembola): Possible hazard to the population level and soil function
PubMed:[Case report-fatal snail bait (metaldehyde) overdose presenting aspiration pneumonia]
PubMed:Anti-convulsant activity of diazepam and clonidine on metaldehyde-induced seizures in mice: effects on brain gamma-amino butyric acid concentrations and monoamine oxidase activity
PubMed:Attempted suicide with a pesticide mixture
PubMed:Reproductive Ecology of the Giant African Snail in South Florida: Implications for Eradication Programs
PubMed:Effect of prolonged status epilepticus as a result of intoxication on epileptogenesis in a UK canine population
PubMed:[Comparison of molluscicidal cost and effectiveness between 5% niclosamide ethanolamine salt granules and 26% suspension concentrate of metalaldehyde and niclosamide ethanolamine salt]
PubMed:Relationships between past and present pesticide applications and pollution at a watershed outlet: The case of a horticultural catchment in Martinique, French West Indies
PubMed:Molluscicidal activity of cardiac glycosides from Nerium indicum against Pomacea canaliculata and its implications for the mechanisms of toxicity
PubMed:[Reaction of metaldehyde with indoles]
PubMed:[Effects and cost of four formulations of niclosamide ethanolamine salt in Oncomelania hupensis snail control in field]
PubMed:Metaldehyde poisoning in horses (two case reports)
PubMed:Backbone cyclised peptides from plants show molluscicidal activity against the rice pest Pomacea canaliculata (golden apple snail)
PubMed:Letter: Toxicity of metaldehyde to dogs
PubMed:Pesticide poisoning of livestock: a review of cases investigated
PubMed:Snails and slugs damaging the cut foliage, Cordyline fruticosa and use of biorationals towards their management
PubMed:Selected fatty acids as biomarkers of exposure to microdoses of molluscicides in snails Helix pomatia (Gastropoda Pulmonata)
PubMed:Anaesthetic control for metaldehyde poisoning
PubMed:[Oncomelania hupensis snail control effects of molluscicides with different formulations in field in marshland and lake regions]
PubMed:Control measures for slug and snail hosts of Angiostrongylus cantonensis, with special reference to the semi-slug Parmarion martensi
PubMed:Death by caffeine: presumptive malicious poisoning of a dog by incorporation in ground meat
PubMed:Pesticide pressure and fish farming in barrage pond in Northeastern France Part I: site characterization and water quality
PubMed:[Poisoning with meta (metaldehyde) in a horse]
PubMed:Danger to dogs of metaldehyde pellets
PubMed:Ultraviolet absorption of contaminants in water
PubMed:Thin layer chromatography of metaldehyde
PubMed:Thin layer chromatography convulsant screen extended by gas chromatography-mass spectrometry
PubMed:Epidemiological features of snail and slug bait poisoning in dogs and cats
PubMed:The incidence and seasonal characteristics of veterinary toxicoses in Saskatchewan
PubMed:A laboratory-based comparison of a molluscicide and an alternative food source (red clover) as means of reducing slug damage to winter wheat
PubMed:Effects of granulated baits on meso and macrofauna in soybean soil system
PubMed:The identification of metaldehyde by Koflers' micro method
PubMed:Inhibition of feeding responses by the molluscicide, metaldehyde
PubMed:Five common toxins and activated charcoal: part 2
PubMed:The Enhancement of H2O2/UV AOPs for the Removal of Selected Organic Pollutants from Drinking Water with Hydrodynamic Cavitation
PubMed:[Materials for hygienic standardization of metaldehyde in the air of the working area]
PubMed:Pacific oyster (Crassostrea gigas) hemocyte are not affected by a mixture of pesticides in short-term in vitro assays
PubMed:[Molluscicidal effect comparison between TDS and MNSC in field]
PubMed:The determination of metaldehyde in biological material by head-space gas chromatography
PubMed:Technique of recording slug movement and some results of tests with metaldehyde and bran, and bran baits only
PubMed:[Renal repercussions of metaldehyde poisoning; attempted pathogenetic interpretation]
PubMed:[Molluscicidal effect of WPN and MNSC on Lymnaea]
PubMed:Surveillance. SAC C vs disease surveillance report. Cases of poisoning in Scottish cattle and sheep
PubMed:Evaluation of a UV-light emitting diodes unit for the removal of micropollutants in water for low energy advanced oxidation processes
PubMed:[Acute poisonings and convulsive crises. Electroencephalographic study of 3 very different products: Rimifon, chloralose, metaldehyde]
PubMed:4-week oral toxicity study of a combination of eight chemicals in rats: comparison with the toxicity of the individual compounds
PubMed:[Field evaluation of a novel plant molluscicide "Luo-wei" against Oncomelania hupensis snails II molluscicidal effect in the field of lake areas in Hanchuan City, Hubei Province]
PubMed:The determination of volatile carbonyl compounds in diagnostic samples
PubMed:[Suicide by methaldehyde]
PubMed:[Molluscicidal effect of 5% niclosamide ethanolamine granules against Oncomelania hupensis in a marshland field]
PubMed:Toxicant adsorption on activated charcoal: is the fraction adsorbed a unique function of the charcoal:adsorbate ratio?
PubMed:Toxic pneumonitis in an adolescent following exposure to Snow Storm tablets
PubMed:Poisoning of animals in the Los Angeles area with pesticides during 1977
PubMed:Toxicity episodes involving agricultural chemicals and other substances in birds in Victoria, Australia
 
Notes:
None found
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