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Category:direct-contact freezing agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 98.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Boiling Point: | -29.77 °C. @ 760.00 mm Hg (est)
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| Vapor Pressure: | 4850.000000 mmHg @ 25.00 °C. |
| Flash Point: | -101.00 °F. TCC ( -74.00 °C. ) (est)
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| logP (o/w): | 2.160 |
| Soluble in: |
| | water, 280 mg/L @ 25 °C (exp) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-rat LD50 > 5600 mg/kg
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 52(3), Pg. 73, 1987.
oral-rat LD > 5600 ug/kg
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 52(3), Pg. 73, 1987.
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
inhalation-rat LC50 > 80 pph/4H
National Technical Information Service. Vol. OTS0520424
inhalation-rabbit LC50 80 pph/4H
European Journal of Toxicology and Environmental Hygiene. Vol. 9, Pg. 385, 1976.
inhalation-mouse LC50 3348 gm/m3/3H
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 28(6), Pg. 95, 1963.
inhalation-guinea pig LC50 80 pph/30M
European Journal of Toxicology and Environmental Hygiene. Vol. 9, Pg. 385, 1976.
inhalation-human TCLo 200000 ppm/30M
SENSE ORGANS AND SPECIAL SENSES: CONJUNCTIVE IRRITATION: EYE
LUNGS, THORAX, OR RESPIRATION: FIBROSING ALVEOLITIS
LIVER: OTHER CHANGES
European Journal of Toxicology and Environmental Hygiene. Vol. 9, Pg. 385, 1976.
inhalation-mouse LC50 3348000 mg/m3/3H
BEHAVIORAL: SLEEP
BEHAVIORAL: TREMOR
BEHAVIORAL: EXCITEMENT
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 28(6), Pg. 95, 1963.
inhalation-rabbit LC50 80 pph/30M
European Journal of Toxicology and Environmental Hygiene. Vol. 9, Pg. 385, 1976.
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Safety in Use Information:
| Category: | | direct-contact freezing agents |
| Recommendation for dichlorodifluoromethane usage levels up to: | | | not for fragrance use.
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| Recommendation for dichlorodifluoromethane flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
| | found in food but not in nature |
Synonyms:
| | carbon dichloride difluoride | | | chladone 12 | | | chlorofluorocarbon 12 | | | dichloro(difluoro)methane | | | dichlorodifluormethane | | | dichlorodifluoromethane [R12] [UN1028] [Nonflammable gas] | | | difluorodichloromethane | | | fluorocarbon 12 | | | forane 12 | | | freon 12 | | | freon F-12 | | | frigen R12 | | | genetron 12 | | | halocarbon 12 | | | halon | | | isceon 122 | | | khladon 12 | | | methane, dichlorodifluoro- | | | refrigerant R12 |
Articles:
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refrigerant,aerosol propellant. Direct contact freezing agent for foods. Refrigerant, aerosol propellant
Dichlorodifluoromethane (R-12), usually sold under the brand name Freon-12, is a chlorofluorocarbon halomethane (CFC), used as a refrigerant and aerosol spray propellant. Complying with the Montreal Protocol, its manufacture was banned in the United States along with many other countries in 1994 due to concerns about damage to the ozone layer. It is soluble in many organic solvents.
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3D/inchi