laureth-10
poly(oxy-1,2-ethanediyl), .alpha.-dodecyl-.omega.-hydroxy- (10 mol EO average molar ratio)

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  CODE130730 CODE130730
  Product(s):
  6540-99-4 Decaethylene Glycol Monodecyl Ether pH (1%, solution):3.0

CAS Number: 6540-99-4 3D/inchi FDA UNII: Search Nikkaji Web: J740.903F XlogP3: 3.80 (est) Molecular Weight: 626.86922000 Formula: C32 H66 O11 BioActivity Summary: listing NMR Predictor: Predict (works with chrome, Edge or firefox) CAS Number: 9002-92-0 3D/inchi Other(deleted CASRN): 101008-55-3 ECHA ELINCS - REACH Pre-Reg: 500-002-6 FDA UNII: 89TKQ5R54 Nikkaji Web: J92.963H XlogP3: 5.10 (est) Formula: (C2 H4 O)mult-C12 H26 O NMR Predictor: Predict (works with chrome, Edge or firefox) Also(can) Contains: ethoxylated C10-16 alcohols Category:emulsifiers, surfactants   US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information: Google Scholar: Search Google Books: Search Google Scholar: with word "volatile" Search Google Scholar: with word "flavor" Search Google Scholar: with word "odor" Search Google Patents: Search US Patents: Search EU Patents: Search Pubchem Patents: Search PubMed: Search NCBI: Search   Physical Properties: Assay: 95.00 to 100.00 Food Chemicals Codex Listed: No Boiling Point: 645.10 °C. @ 760.00 mm Hg (est) Flash Point: 651.00 °F. TCC ( 344.00 °C. ) (est) logP (o/w): 1.820 (est)   Organoleptic Properties: Odor and/or flavor descriptions from others (if found).   Cosmetic Information: CosIng: cosmetic data Cosmetic Uses: surfactants surfactant - emulsifying   Suppliers: BOC Sciences For experimental / research use only. Decaethylene Glycol Monodecyl Ether pH (1%, solution):3.0 Universal Preserv-A-Chem Inc. Laureth-10 Odor: characteristic Use: In cosmetics and personal care products, the laureth ingredients are used in the formulation of a variety of bath, eye, facial, hair, cleansing and sunscreen products. They are also used in cuticle softeners, deodorants and moisturizing products.   Safety Information:   Hazards identification   Classification of the substance or mixture GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) None found. GHS Label elements, including precautionary statements   Pictogram   Hazard statement(s) None found. Precautionary statement(s) None found. Oral/Parenteral Toxicity: intravenous-guinea pig LD50 38 mg/kg BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) KIDNEY, URETER, AND BLADDER: HEMATURIA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Arzneimittel-Forschung. Drug Research. Vol. 7, Pg. 162, 1957. oral-guinea pig LD50 384 mg/kg PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Arzneimittel-Forschung. Drug Research. Vol. 7, Pg. 162, 1957. intraperitoneal-mouse LD50 160 mg/kg Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 967, 1991. intraperitoneal-mouse LD50 160 mg/kg Drugs in Japan Vol. -, Pg. 1300, 1995. intravenous-mouse LD50 100 mg/kg Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 967, 1991. intravenous-mouse LD50 100 mg/kg Toxicology and Applied Pharmacology. Vol. 7, Pg. 206, 1965. oral-mouse LD50 1170 mg/kg Toxicology and Applied Pharmacology. Vol. 2, Pg. 133, 1960. oral-mouse LD50 1170 mg/kg PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Arzneimittel-Forschung. Drug Research. Vol. 7, Pg. 162, 1957. oral-mouse LD50 3500 mg/kg American Perfumer and Cosmetics. Vol. 77, Pg. 35, 1962. oral-mouse LD50 4940 mg/kg American Perfumer and Cosmetics. Vol. 77, Pg. 35, 1962. intratracheal-rabbit LD50 > 15 mg/kg Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 78, 1976. intravenous-rabbit LD50 36 mg/kg KIDNEY, URETER, AND BLADDER: HEMATURIA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) Arzneimittel-Forschung. Drug Research. Vol. 7, Pg. 162, 1957. parenteral-rabbit LD50 > 75 mg/kg Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 78, 1976. intraperitoneal-rat LD50 125 mg/kg GASTROINTESTINAL: OTHER CHANGES Food and Cosmetics Toxicology. Vol. 8, Pg. 125, 1970. intravenous-rat LD50 27 mg/kg Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 967, 1991. intravenous-rat LD50 27 mg/kg Drugs in Japan Vol. -, Pg. 1300, 1995. intravenous-rat LD50 390 mg/kg Toxicology and Applied Pharmacology. Vol. 2, Pg. 133, 1960. oral-rat LD50 1000 mg/kg LIVER: FATTY LIVER DEGERATION GASTROINTESTINAL: OTHER CHANGES GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH Food and Cosmetics Toxicology. Vol. 8, Pg. 125, 1970. oral-rat LD50 4150 mg/kg Toxicology and Applied Pharmacology. Vol. 2, Pg. 133, 1960. oral-rat LD50 8600 mg/kg Soap, Perfumery & Cosmetics. Vol. 38, Pg. 47, 1965. Dermal Toxicity: subcutaneous-mouse LD50 792 mg/kg Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 967, 1991. subcutaneous-mouse LD50 792300 ug/kg Drugs in Japan Vol. -, Pg. 1300, 1995. subcutaneous-rat LD50 953 mg/kg Drugs in Japan Vol. -, Pg. 1300, 1995. subcutaneous-rat LD50 954 mg/kg Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 967, 1991. Inhalation Toxicity: Not determined   Safety in Use Information: Category: emulsifiers, surfactants Recommendation for laureth-10 usage levels up to:   not for fragrance use.   Recommendation for laureth-10 flavor usage levels up to:   not for flavor use.   Safety References: EPI System: View ClinicalTrials.gov:search Chemical Carcinogenesis Research Information System:Search AIDS Citations:Search Cancer Citations:Search Toxicology Citations:Search EPA Substance Registry Services (TSCA):6540-99-4 EPA ACToR:Toxicology Data EPA Substance Registry Services (SRS):Registry Laboratory Chemical Safety Summary :145870 National Institute of Allergy and Infectious Diseases:Data WGK Germany:2 2-[2-[2-[2-[2-[2-[2-[2-[2-(2-dodecoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol Chemidplus:0006540994 2-dodecoxyethanol (peg-10) Chemidplus:0009002920 EPA/NOAA CAMEO:hazardous materials   References:   2-[2-[2-[2-[2-[2-[2-[2-[2-(2-dodecoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol NIST Chemistry WebBook: Search Inchi Canada Domestic Sub. List: 6540-99-4 Pubchem (cid): 145870 Pubchem (sid): 135102162   2-dodecoxyethanol (peg-10) NIST Chemistry WebBook: Search Inchi Canada Domestic Sub. List: 9002-92-0 Pubchem (cid): 24750 Pubchem (sid): 134991393   Other Information: (IUPAC): Atomic Weights of the Elements 2011 (pdf) Videos: The Periodic Table of Videos tgsc: Atomic Weights use for this web site (IUPAC): Periodic Table of the Elements CHEBI: View CHEMBL: View KEGG (GenomeNet): D01539 HMDB (The Human Metabolome Database): Search ChemSpider: View   Potential Blenders and core components note None Found   Potential Uses: None Found   Occurrence (nature, food, other):note   not found in nature   Synonyms:   britex L 100 2- dodecoxyethanol (peg-10)   peg-10 lauryl ether   poly(oxy-1,2-ethanediyl), .alpha.-dodecyl-.omega.-hydroxy- (10 mol EO average molar ratio)   polyethylene glycol (10) lauryl ether   polyethylene glycol (10) monolauryl ether   polyoxyethylene (10) lauryl ether   polyoxyethylene (10) monolauryl ether   Articles:   None found yet. Try the PubMed Search.

Notes: polyethylene glycol monododecyl ether (average polymer n=9).