EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

dextrans

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CAS Number: 9004-54-0Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:232-677-5
FDA UNII: EW7Q6SVD0D
XlogP3-AA:-7.20 (est)
Molecular Weight:504.44024000
Formula:C18 H32 O16
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:food-contact surface of paper and paperboard
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 FDA/DG SANTE Petitions, Reviews, Notices:
186.1275 Dextrans View - review
186.1275 Dextran View - review
FDA Mainterm (SATF):9004-54-0 ; DEXTRANS (AVG M W LESS THAN 100,000)
FDA Regulation:
FDA PART 186 -- INDIRECT FOOD SUBSTANCES AFFIRMED AS GENERALLY RECOGNIZED AS SAFE
Subpart B--Listing of Specific Substances Affirmed as GRAS
Sec. 186.1275 Dextrans.
 
Physical Properties:
Food Chemicals Codex Listed: No
Boiling Point: 952.80 °C. @ 760.00 mm Hg (est)
Flash Point: 622.00 °F. TCC ( 327.70 °C. ) (est)
logP (o/w): -4.259 (est)
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: binding agents
viscosity controlling agents
 
Suppliers:
BOC Sciences
For experimental / research use only.
Dextran 110 - MW: 100,000 to 120,000
Glentham Life Sciences
Dextran 1,000
Glentham Life Sciences
Dextran 40,000
Glentham Life Sciences
Dextran 70,000
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
unreported-mammal (species unspecified) LD50 13500 mg/kg
BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Gematologiya i Transfuziologiya. Hematology and Transfusion Science. Vol. 31(10), Pg. 38, 1986.

intravenous-mouse LD50 12100 mg/kg
Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 1023, 1972.

oral-mouse LD50 > 12000 mg/kg
Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 1023, 1972.

intravenous-rabbit LD50 17400 mg/kg
BEHAVIORAL: ATAXIA BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 1023, 1972.

intravenous-rabbit LD50 208000 mg/kg
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) LUNGS, THORAX, OR RESPIRATION: CYANOSIS
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 3, Pg. 201, 1975.

intravenous-rat LD50 6900 mg/kg
Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 1023, 1972.

oral-rat LD50 > 3000 mg/kg
Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 1023, 1972.

Dermal Toxicity:
subcutaneous-mouse LD50 13900 mg/kg
Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 1023, 1972.

subcutaneous-rat LD50 10700 mg/kg
Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 1023, 1972.

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
food-contact surface of paper and paperboard
Recommendation for dextrans usage levels up to:
 not for fragrance use.
 
Recommendation for dextrans flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
ClinicalTrials.gov:search
Daily Med:search
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
Carcinogenic Potency Database:Search
EPA Substance Registry Services (TSCA):9004-54-0
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :4125253
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
2,3,4,5-tetrahydroxy-6-[3,4,5-trihydroxy-6-[[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxyhexanal
Chemidplus:0009004540
 
References:
 2,3,4,5-tetrahydroxy-6-[3,4,5-trihydroxy-6-[[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxyhexanal
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:9004-54-0
Pubchem (cid):4125253
Pubchem (sid):135289239
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
FDA Indirect Additives used in Food Contact Substances:View
KEGG (GenomeNet):C00372
HMDB (The Human Metabolome Database):Search
FooDB:FDB012591
MedlinePlusSupp:View
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
 binding agents
 viscosity controlling agents
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 dextran 4
 dextran 8
2,3,4,5-tetrahydroxy-6-[3,4,5-trihydroxy-6-[[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxyhexanal
 
 
Notes:
a group of glucose polymers made by certain bacteria. dextrans are used therapeutically as plasma volume expanders and anticoagulants. they are also commonly used in biological experimentation and in industry for a wide variety of purposes. Indirect food additive produced by bacterial fermentation of sucrose Dextran is a complex, branched glucan (polysaccharide made of many glucose molecules) composed of chains of varying lengths (from 10 to 150 kilodaltons). It is used medicinally as an antithrombotic (anti-platelet), to reduce blood viscosity, and as a volume expander in anemia.
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