Category:cosmetic agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Appearance: | colorless to pale yellow clear oily liquid (est) |
Assay: | 95.00 to 100.00
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Food Chemicals Codex Listed: | No |
Specific Gravity: | 0.95930 @ 20.00 °C.
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Refractive Index: | 1.39820 @ 20.00 °C.
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Melting Point: | -38.00 °C. @ 760.00 mm Hg
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Boiling Point: | 210.00 °C. @ 760.00 mm Hg
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Boiling Point: | 209.00 to 210.00 °C. @ 760.00 mm Hg (est)
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Vapor Pressure: | 0.200000 mmHg @ 25.00 °C. |
Flash Point: | 204.00 °F. TCC ( 95.60 °C. ) (est)
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logP (o/w): | 5.200 |
Soluble in: |
| water, 0.017 mg/L @ 25 °C (exp) |
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
BOC Sciences |
For experimental / research use only. |
Decamethylcyclopentasiloxane >99.0%(GC)
Odor: characteristic Use: A cyclic volatile methylsiloxane (cVMS) used in cosmetic and personal care products. Used in dermal exposure and inh |
ECSA Chemicals |
CYCLOPENTASILOXANE + CYCLOHEXASILOXANE
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ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY |
ECSA Chemicals |
CYCLOPENTASILOXANE HIGH PURITY
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ECSA Chemicals |
CYCLOPENTASILOXANE
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Indis NV |
For experimental / research use only. |
Cyclopentasiloxane (D5)
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OQEMA |
LanCos SI25
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Sigma-Aldrich: Aldrich |
For experimental / research use only. |
Decamethylcyclopentasiloxane 97%
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Siltech |
Siltech CF-955
Odor: characteristic Use: Siltech®CF-955 is an excellent carrier for oils and greases and for active ingredients. Siltech®CF-955 can also be used as to clean various substrates where removal of greases, silicone fluids or waxes is important. Leaves a soft, silky feel in cosmetic formulations. |
Universal Preserv-A-Chem Inc. |
Cyclopentasiloxane; Dimethiconol
Odor: characteristic Use: ABIL OSW 5 is also suitable as a conditioner that improves the structure of treated damaged hair after repeated permanent waving or oxidative dyeing. |
Universal Preserv-A-Chem Inc. |
CYCLOPENTASILOXANE
Odor: characteristic Use: Used for excellent spreading, fast evaporation leaving no residue or build-up, leaves a unique soft feel and lubricity; non-greasy feel, non-occlusive and non-irritating. Used in conditioners, hair sprays, face wash, body wash, make-up, sun care, antiperspirants, and deodorants. |
Safety Information:
Preferred SDS: View |
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
oral-rat LD50 > 24134 mg/kg National Technical Information Service. Vol. OTS0572801
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Dermal Toxicity: |
skin-rabbit LD50 > 16 mL/kg Toxicology and Applied Pharmacology. Vol. 28, Pg. 313, 1974.
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Inhalation Toxicity: |
inhalation-rat LC > 2700 mg/m3/4H National Technical Information Service. Vol. OTS0572802
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Safety in Use Information:
Category: | cosmetic agents |
Recommendation for cyclopentasiloxane usage levels up to: | | not for fragrance use.
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Recommendation for cyclopentasiloxane flavor usage levels up to: |
| not for flavor use.
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Safety References:
EPI System: View |
Chemical Carcinogenesis Research Information System:Search |
AIDS Citations:Search |
Cancer Citations:Search |
Toxicology Citations:Search |
EPA GENetic TOXicology:Search |
EPA Substance Registry Services (TSCA):541-02-6 |
EPA ACToR:Toxicology Data |
EPA Substance Registry Services (SRS):Registry |
Laboratory Chemical Safety Summary :10913 |
National Institute of Allergy and Infectious Diseases:Data |
WGK Germany:2 |
2,2,4,4,6,6,8,8,10,10-decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane |
Chemidplus:0000541026 |
RTECS:GY5945200 for cas# 541-02-6 |
References:
| 2,2,4,4,6,6,8,8,10,10-decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane |
NIST Chemistry WebBook: | Search Inchi |
Canada Domestic Sub. List: | 541-02-6 |
Pubchem (cid): | 10913 |
Pubchem (sid): | 134975748 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| cyclopentasiloxane, 2,2,4,4,6,6,8,8,10,10-decamethyl- | | decamethyl cyclopentasiloxane | 2,2,4,4,6,6,8,8,10,10- | decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane | 2,2,4,4,6,6,8,8,10,10- | decamethyl-1,3,5,7,9,2,4,6,8,10-pentoxapentasilecan | 2,2,4,4,6,6,8,8,10,10- | decamethyl-1,3,5,7,9,2,4,6,8,10-pentoxapentasilecane | | decamethylcyclopentasiloxane | | dow corning 345 | | silicon SF 1202 | | union carbide 7158 silicone fluid |
Articles:
PubMed:Determination of soil-water sorption coefficients of volatile methyl siloxanes. |
PubMed:Sensitive Method for Quantification of Octamethylcyclotetrasiloxane (D4) and Decamethylcyclopentasiloxane (D5) in End-Exhaled Air by Thermal Desorption Gas Chromatography Mass Spectrometry. |
PubMed:Allometric relationships to liver tissue concentrations of cyclic volatile methyl siloxanes in Atlantic cod. |
PubMed:Emissions of decamethylcyclopentasiloxane from Chicago. |
PubMed:Concentrations and trophic magnification of cyclic siloxanes in aquatic biota from the Western Basin of Lake Erie, Canada. |
PubMed:Consistency in trophic magnification factors of cyclic methyl siloxanes in pelagic freshwater food webs leading to brown trout. |
PubMed:Concentrations of cyclic volatile methylsiloxanes in European cosmetics and personal care products: prerequisite for human and environmental exposure assessment. |
PubMed:Emergence and fate of cyclic volatile polydimethylsiloxanes (D4, D5) in municipal waste streams: release mechanisms, partitioning and persistence in air, water, soil and sediments. |
PubMed:Compound allergy to a lipophilic gel containing vitamin E acetate and cyclopentasiloxane. |
PubMed:Water-in-oil emulsions prepared by peptide-silicone hybrid polymers as active interfacial modifier: effects of silicone oil species on dispersion stability of emulsions. |
PubMed:Composition and source identification of deposits forming in landfill gas (LFG) engines and effect of activated carbon treatment on deposit composition. |
PubMed:Adsorption characteristics of siloxanes in landfill gas by the adsorption equilibrium test. |
PubMed:Cyclic siloxanes in air, including identification of high levels in Chicago and distinct diurnal variation. |
PubMed:Calibration and application of a passive air sampler (XAD-PAS) for volatile methyl siloxanes. |
PubMed:Concentrations in ambient air and emissions of cyclic volatile methylsiloxanes in Zurich, Switzerland. |
PubMed:Selected ion flow tube studies of several siloxanes. |
PubMed:VOC contamination in hospital, from stationary sampling of a large panel of compounds, in view of healthcare workers and patients exposure assessment. |
PubMed:Evaluating the fate and behaviour of cyclic volatile methyl siloxanes in two contrasting North American lakes using a multi-media model. |
PubMed:Decamethylcyclopentasiloxane (D5) spiked sediment: bioaccumulation and toxicity to the benthic invertebrate Hyalella azteca. |
PubMed:Fathead minnow (Pimephales promelas) embryo to adult exposure to decamethylcyclopentasiloxane (D5). |
PubMed:Bioaccumulation of decamethylcyclopentasiloxane in perch in Swedish lakes. |
PubMed:Occurrence of linear and cyclic volatile methylsiloxanes in wastewater, surface water and sediments from Catalonia. |
PubMed:Uncertainty analysis using a fugacity-based multimedia mass-balance model: application of the updated EQC model to decamethylcyclopentasiloxane (D5). |
PubMed:Determination of cyclic volatile methylsiloxanes in water, sediment, soil, biota, and biosolid using large-volume injection-gas chromatography-mass spectrometry. |
PubMed:Review of recent advances in research on the toxicity, detection, occurrence and fate of cyclic volatile methyl siloxanes in the environment. |
PubMed:Plasma concentrations of cyclic volatile methylsiloxanes (cVMS) in pregnant and postmenopausal Norwegian women and self-reported use of personal care products (PCPs). |
PubMed:Determination of the dietary biomagnification of octamethylcyclotetrasiloxane and decamethylcyclopentasiloxane with the rainbow trout (Oncorhynchus mykiss). |
PubMed:Occurrence and seasonality of cyclic volatile methyl siloxanes in Arctic air. |
PubMed:Accounting for intended use application in characterizing the contributions of cyclopentasiloxane (D5) to aquatic loadings following personal care product use: antiperspirants, skin care products and hair care products. |
PubMed:Occurrence and fate of volatile siloxanes in a municipal wastewater treatment plant of Beijing, China. |
PubMed:Cyclic volatile methylsiloxanes in fish from the Baltic Sea. |
PubMed:Simulated use and wash-off release of decamethylcyclopentasiloxane used in anti-perspirants. |
PubMed:Junge relationships in measurement data for cyclic siloxanes in air. |
PubMed:Concentrations of cyclic volatile methylsiloxanes in biosolid amended soil, influent, effluent, receiving water, and sediment of wastewater treatment plants in Canada. |
PubMed:Characterization of low-k dielectric SiCOH films deposited with decamethylcyclopentasiloxane and cyclohexane. |
PubMed:Determination of siloxanes in silicone products and potential migration to milk, formula and liquid simulants. |
PubMed:Food web accumulation of cyclic siloxanes in Lake Mjøsa, Norway. |
PubMed:Method for simultaneous determination of partition coefficients for cyclic volatile methylsiloxanes and dimethylsilanediol. |
PubMed:Safety assessment of cyclomethicone, cyclotetrasiloxane, cyclopentasiloxane, cyclohexasiloxane, and cycloheptasiloxane. |
PubMed:An updated state of the science EQC model for evaluating chemical fate in the environment: application to D5 (decamethylcyclopentasiloxane). |
PubMed:Ecotoxicity of siloxane D5 in soil. |
PubMed:A study of pyrolysis of polymethylsiloxanes by Fourier transform infrared. |
PubMed:Prioritizing organic chemicals for long-term air monitoring by using empirical monitoring data--application to data from the Swedish screening program. |
PubMed:Volatile organic compounds in small- and medium-sized commercial buildings in California. |
PubMed:Measuring chemical emissions from wet products--development of a new measurement technique. |
PubMed:Cyclic volatile methylsiloxane bioaccumulation in flounder and ragworm in the Humber Estuary. |
PubMed:BETR global--a geographically-explicit global-scale multimedia contaminant fate model. |
PubMed:Determination of decamethylcyclopentasiloxane in river and estuarine sediments in the UK. |
PubMed:Survey of cyclic and linear siloxanes in sediment from the Songhua River and in sewage sludge from wastewater treatment plants, Northeastern China. |
PubMed:Determination of cyclic volatile methylsiloxanes in biota with a purge and trap method. |
PubMed:Determination of cyclic and linear siloxanes in soil samples by ultrasonic-assisted extraction and gas chromatography-mass spectrometry. |
PubMed:Volatile siloxanes in the European arctic: assessment of sources and spatial distribution. |
PubMed:Occurrence of cyclic and linear siloxanes in indoor dust from China, and implications for human exposures. |
PubMed:Concentrations and fate of decamethylcyclopentasiloxane (D(5)) in the atmosphere. |
PubMed:Dynamic multi-phase partitioning of decamethylcyclopentasiloxane (D5) in river water. |
PubMed:Determination of decamethylcyclopentasiloxane in air using commercial solid phase extraction cartridges. |
PubMed:Active interfacial modifier: stabilization mechanism of water in silicone oil emulsions by peptide-silicone hybrid polymers. |
PubMed:Study on penetration of titanium dioxide (TiO(2)) nanoparticles into intact and damaged skin in vitro. |
PubMed:Quantitative analysis of volatile methylsiloxanes in waste-to-energy landfill biogases using direct APCI-MS/MS. |
PubMed:Modelling concentrations of decamethylcyclopentasiloxane in two UK rivers using LF2000-WQX. |
PubMed:Direct analysis of volatile methylsiloxanes in gaseous matrixes using atmospheric pressure chemical ionization-tandem mass spectrometry. |
PubMed:Effect of ozone and relative humidity on the heterogeneous uptake of octamethylcyclotetrasiloxane and decamethylcyclopentasiloxane on model mineral dust aerosol components. |
PubMed:Low molecular weight cyclic volatile methylsiloxanes in cosmetic products sold in Canada: implication for dermal exposure. |
PubMed:Effect of Aldrich humic acid on water-atmosphere transfer of decamethylcyclopentasiloxane. |
PubMed:A mechanistic study of cyclic siloxane pyrolyses at low pressures. |
PubMed:Determination of decamethylcyclopentasiloxane in river water and final effluent by headspace gas chromatography/mass spectrometry. |
PubMed:[Analysis of the volatile oils chemical constituents of roots of Actinidia deliciosa]. |
PubMed:Inhalation dosimetry modeling with decamethylcyclopentasiloxane in rats and humans. |
PubMed:Are highly lipophilic volatile compounds expected to bioaccumulate with repeated exposures? |
PubMed:Protective effect of conditioning agents on Afro-ethnic hair chemically treated with thioglycolate-based straightening emulsion. |
PubMed:Survey of organosilicone compounds, including cyclic and linear siloxanes, in personal-care and household products. |
PubMed:Disposition of decamethylcyclopentasiloxane in Fischer 344 rats following single or repeated inhalation exposure to 14C-decamethylcyclopentasiloxane (14C-D5). |
PubMed:In vitro and in vivo percutaneous absorption of 14C-octamethylcyclotetrasiloxane (14C-D4) and 14C-decamethylcyclopentasiloxane (14C-D5). |
PubMed:Fabrication of spatially periodic double roughness structures by directional viscous fingering and spinodal dewetting for water-repellent surfaces. |
PubMed:Modeling of human dermal absorption of octamethylcyclotetrasiloxane (D(4)) and decamethylcyclopentasiloxane (D(5)). |
PubMed:Recent progress in the determination of solid surface tensions from contact angles. |
PubMed:In vitro and in vivo evaluation of the estrogenic, androgenic, and progestagenic potential of two cyclic siloxanes. |
PubMed:A two-generation reproductive toxicity study of decamethylcyclopentasiloxane (D5) in rats exposed by whole-body vapor inhalation. |
PubMed:Novel anhydrous emulsions: formulation as controlled release vehicles. |
PubMed:Interpretation of contact angle measurements on two different fluoropolymers for the determination of solid surface tension. |
PubMed:Octamethylcyclotetrasiloxane exhibits estrogenic activity in mice via ERalpha. |
PubMed:Highly activated, silicone entrapped, lipase. |
PubMed:Beyond rheology modification: hydrophilically modified silicone elastomers provide new benefits. |
PubMed:The measurement of conformational stability of proteins adsorbed on siloxanes. |
PubMed:Determination of siloxanes, silicon, and platinum in tissues of women with silicone gel-filled implants. |
PubMed:Metabolites of hexamethyldisiloxane and decamethylcyclopentasiloxane in Fischer 344 rat urine--a comparison of a linear and a cyclic siloxane. |
PubMed:Determination of low molecular weight silicones in plasma and blood of women after exposure to silicone breast implants by GC/MS. |
PubMed:Induction of rat hepatic drug metabolizing enzymes by dimethylcyclosiloxanes. |
PubMed:Toxicology and humoral immunity assessment of octamethylcyclotetrasiloxane (D4) following a 28-day whole body vapor inhalation exposure in Fischer 344 rats. |
PubMed:Induction of hepatic xenobiotic metabolizing enzymes in female Fischer-344 rats following repeated inhalation exposure to decamethylcyclopentasiloxane (D5). |
PubMed:Cyclosiloxanes produce fatal liver and lung damage in mice. |
PubMed:Inhalation toxicology of decamethylcyclopentasiloxane (D5) following a 3-month nose-only exposure in Fischer 344 rats. |
PubMed:Toxicology and humoral immunity assessment of decamethylcyclopentasiloxane (D5) following a 1-month whole body inhalation exposure in Fischer 344 rats. |
PubMed:Low molecular weight silicones are widely distributed after a single subcutaneous injection in mice. |
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