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copper powder

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CAS Number: 7440-50-8Picture of molecule3D/inchi
Other(deleted CASRN):133353-46-5
ECHA EINECS - REACH Pre-Reg:231-159-6
FDA UNII: 789U1901C5
Nikkaji Web:J3.733H
MDL:MFCD00010965
Molecular Weight:63.54600000
Formula:Cu
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:coloring agents (for surface only)
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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NCBI:Search
FDA Mainterm (SATF): Copper powder
FDA Regulation:
FDA PART 73-LISTING OF COLOR ADDITIVES EXEMPT FROM CERTIFICATION
Subpart B-Drugs
Sec. 73.1647 Copper powder.
 
Physical Properties:
Appearance:Reddish metallic solid (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point:1083.00 °C. @ 760.00 mm Hg (est)
Boiling Point:2595.00 °C. @ 760.00 mm Hg (est)
Vapor Pressure:1.000000 mmHg @ 1.00 °C. (est)
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: cosmetic colorants
 
Suppliers:
ECSA Chemicals
COPPER ELECTROLYTIC WIRE RPE-FOR ANALYSIS, K
ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-human TDLo 120 ug/kg
GASTROINTESTINAL: NAUSEA OR VOMITING
Public Health Reports. Vol. 73, Pg. 910, 1958.

intraperitoneal-mouse LD50 3500 ug/kg
"Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2A, Pg. 1623, 1981.

Dermal Toxicity:
subcutaneous-rabbit LDLo 375 mg/kg
LIVER: OTHER CHANGES KIDNEY, URETER, AND BLADDER: OTHER CHANGES LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), ZONAL"
American Journal of Pathology. Vol. 1, Pg. 117, 1925.

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
coloring agents (for surface only)
Recommendation for copper powder usage levels up to:
 not for fragrance use.
 
Recommendation for copper powder flavor usage levels up to:
 not for flavor use.
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Outcome of a public consultation on a Draft Scientific Opinion on Dietary Reference Values for copper
View page or View pdf

Scientific Opinion on Dietary Reference Values for copper
View page or View pdf

Final Evidence Report as preparatory work for the setting of Dietary Reference Values for magnesium, copper and phosphorus
View page or View pdf

Extensive Literature Search on the “Effects of Copper intake levels in the gut microbiota profile of target animals, in particular piglets”
View page or View pdf

Revision of the currently authorised maximum copper content in complete feed
View page or View pdf

Review of the existing maximum residue levels for copper compounds according to Article 12 of Regulation (EC) No 396/2005
View page or View pdf

EPI System: View
EPA-Iris:IRIS
ClinicalTrials.gov:search
Daily Med:search
NIOSH International Chemical Safety Cards:search
NIOSH Pocket Guide:search
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):7440-50-8
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :23978
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:nwg
copper
Chemidplus:0007440508
EPA/NOAA CAMEO:hazardous materials
RTECS:7440-50-8
 
References:
 copper
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:7440-50-8
Pubchem (cid):23978
Pubchem (sid):134988662
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
KEGG (GenomeNet):C00070
HMDB (The Human Metabolome Database):HMDB00657
FooDB:FDB003582
FDA Color Additive Status ListView
MedlinePlusSupp:View
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
Formulations/Preparations:
•usepaopp pesticide code 022501; trade names: allbrinatural copper; anac 110; bronze powder; cathode copper; copper bronze; copper m1; cda 102; cda 122; and copper. •commercial copper (cu) is available in six general types: electrolytic tough-pitch, 99.90% cu; deoxidized, 99.90% cu; oxygen-free, 99.92% cu; silver-bearing, 99.90% cu; arsenical, 99.68%; free-cutting, 99.4-99.5% •forms available: ingots, sheet, rod, wire, tubing, shot, powder; high purity (impurities less than 10 ppm) as single crystals or whiskers.
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
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Synonyms:
 c.i. 77400
 C.I. pigment metal 2
 ci 77400
 copper
 cuprum powder
 
 
Notes:
a heavy metal trace element with the atomic symbol cu, atomic number 29, and atomic weight 63.55. Copper (pronounced /?k?p?r/, KOP-?r) is a chemical element with the symbol Cu (Latin: cuprum) and atomic number 29. It is a ductile metal with very high thermal and electrical conductivity. Pure copper is rather soft and malleable and a freshly-exposed surface has a pinkish or peachy color. It is used as a thermal conductor, an electrical conductor, a building material, and a constituent of various metal alloys.; Copper can be found as native copper in mineral form (for example, in Michigan's Keewenaw Peninsula). It is a polycrystal, with the largest single crystals measuring 4.4x3.2x3.2 cm3. Minerals such as the sulfides: chalcopyrite (CuFeS2), bornite (Cu5FeS4), covellite (CuS), chalcocite (Cu2S) are sources of copper, as are the carbonates: azurite (Cu3(CO3)2(OH)2) and malachite (Cu2CO3(OH)2) and the oxide: cuprite (Cu2O).; Copper compounds are known in several oxidation states, usually 2+, where they often impart blue or green colors to natural minerals such as turquoise and have been used historically widely as pigments. Copper as both metal and pigmented salt, has a significant presence in decorative art. Copper 2+ ions are soluble in water, where they function at low concentration as bacteriostatic substances and fungicides. For this reason, copper metal can be used as an anti-germ surface that can add to the anti-bacterial and antimicrobial features of buildings such as hospitals. In sufficient amounts, copper salts can be poisonous to higher organisms as well. However, despite universal toxicity at high concentrations, the 2+ copper ion at lower concentrations is an essential trace nutrient to all higher plant and animal life. In animals, including humans, it is found widely in tissues, with concentration in liver, muscle, and bone. It functions as a co-factor in various enzymes and in copper-based pigments.; Copper has a reddish, orangish, or brownish color because a thin layer of tarnish (including oxides) gradually forms on its surface when gases (especially oxygen) in the air react with it. But pure copper, when fresh, is actually a pinkish or peachy metal. Copper, caesium and gold are the only three elemental metals with a natural color other than gray or silver. The usual gray color of metals depends on their "electron sea" that is capable of absorbing and re-emitting photons over a wide range of frequencies. Copper has its characteristic color because of its unique band structure. By Madelung's rule the 4s subshell should be filled before electrons are placed in the 3d subshell but copper is an exception to the rule with only one electron in the 4s subshell instead of two. The energy of a photon of blue or violet light is sufficient for a d band electron to absorb it and transition to the half-full s band. Thus the light reflected by copper is missing some blue/violet components and appears red. This phenomenon is shared with gold which has a corresponding 5s/4d structure. In its liquefied state, a pure copper surface without ambient light appears somewhat greenish, a characteristic shared with gold. When liquid copper is in bright ambient light, it retains some of its pinkish luster. When copper is burnt in oxygen it gives off a black oxide.; Copper is a finite resource, but, unlike oil, it is not destroyed and therefore can be recycled. Recycling is a major source of copper in the modern world.; Copper is malleable and ductile and is a good conductor of both heat and electricity.; Copper, as native copper, is one of the few metals to occur naturally as an un-compounded mineral. Copper was known to some of the oldest civilizations on record, and has a history of use that is at least 10,000 years old. Some estimates of copper's discovery place this event around 9000 BC in the Middle East. A copper pendant was found in what is now northern Iraq that dates to 8700 BC. It is probable that gold and meteoritic iron were the only metals used by humans before copper. By 5000 BC, there are signs of copper smelting: the refining of copper from simple copper compounds such as malachite or azurite. Among archaeological sites in Anatolia, Çatal Höyük (~6000 BC) features native copper artifacts and smelted lead beads, but no smelted copper. Can Hasan (~5000 BC) had access to smelted copper but the oldest smelted copper artifact found (a copper chisel from the chalcolithic site of Prokuplje in Serbia) has pre-dated Can Hasan by 500 years. The smelting facilities in the Balkans appear to be more advanced than the Turkish forges found at a later date, so it is quite probable that copper smelting originated in the Balkans. Investment casting was realized in 4500-4000 BCE in Southeast Asia.; It is believed that zinc and copper compete for absorption in the digestive tract so that a diet that is excessive in one of these minerals may result in a deficiency in the other. The RDA for copper in normal healthy adults is 0.9 mg/day. On the other hand, professional research on the subject recommends 3.0 mg/day. Because of its role in facilitating iron uptake, copper deficiency can often produce anemia-like symptoms. In humans, the symptoms of Wilson's disease are caused by an accumulation of copper in body tissues.; Numerous copper alloys exist, many with important historical and contemporary uses. Speculum metal and bronze are alloys of copper and tin. Brass is an alloy of copper and zinc. Monel metal, also called cupronickel, is an alloy of copper and nickel. While the metal "bronze" usually refers to copper-tin alloys, it also is a generic term for any alloy of copper, such as aluminium bronze, silicon bronze, and manganese bronze. Copper is one of the most important constituents of carat silver and gold alloys and carat solders used in the jewelry industry, modifying the color, hardness and melting point of the resulting alloys.; The catalytic activity of copper is used by the enzymes that it is associated with and is thus only toxic when unsequestered and unmediated. This increase in unmediated reactive radicals is generally termed oxidative stress and is an active area of research in a variety of diseases where copper may play an important but more subtle role than in acute toxicity. It is believed that zinc and copper compete for absorption in the digestive tract so that a diet that is excessive in one of these minerals may result in a deficiency in the other. Copper is an essential nutrient to all higher plants and animals. Physiologically, it exists as an ion in the body. In animals, it is found primarily in the bloodstream, as a cofactor in various enzymes, and in copper-based pigments. In sufficient amounts, copper can be poisonous or even fatal to organisms.; The metal, when powdered, is a fire hazard. At concentrations higher than 1 mg/L, copper can stain clothes and items washed in water.; The purity of copper is expressed as 4N for 99.99% pure or 7N for 99.99999% pure. The numeral gives the number of nines after the decimal point when expressed as a decimal (e.g. 4N means 0.9999, or 99.99%). Copper is often too soft for its applications, so it is incorporated in numerous alloys. For example, brass is a copper-zinc alloy, and bronze is a copper-tin alloy.
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