EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

tetramethylammonium chloride
methanaminium, N,N,N-trimethyl-, chloride (1:1)

Supplier Sponsors

Name:tetramethylazanium;chloride
CAS Number: 75-57-0Picture of molecule3D/inchi
Other(deleted CASRN):251459-49-1
ECHA EINECS - REACH Pre-Reg:200-880-8
FDA UNII: DCQ9S88703
Beilstein Number:3911201
MDL:MFCD00011628
Molecular Weight:109.59864000
Formula:C4 H12 Cl N
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:viscosity controlling agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
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PubMed:Search
NCBI:Search
 
Physical Properties:
Appearance:white crystalline solid (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 420.00 °C. @ 760.00 mm Hg
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: viscosity controlling agents
 
Suppliers:
BOC Sciences
For experimental / research use only.
Tetramethylammonium chloride 98 % (TLC).
Odor: characteristic
Use: Non-selective K+ channel blocker. ADCs Cytotoxin
Charkit Chemical
TETRAMETHYLAMMONIUM CHLORIDE 30% IN ETHYLENE GLYCOL
Charkit Chemical
TETRAMETHYLAMMONIUM CHLORIDE
EMD Millipore
For experimental / research use only.
Tetramethylammonium Chloride
sds
Glentham Life Sciences
Tetramethylammonium chloride
Santa Cruz Biotechnology
For experimental / research use only.
Tetramethylammonium Chloride ≥99%
Sigma-Aldrich: Sigma
For experimental / research use only.
Tetramethylammonium Chloride BioUltra, for molecular biology, ≥99.0% (AT)
sds
TCI AMERICA
For experimental / research use only.
Tetramethylammonium Chloride >98.0%(T)
sds
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
unreported-guinea pig LDLo 20 mg/kg
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 7, Pg. 183, 1900.

intraperitoneal-mouse LD50 10 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
National Technical Information Service. Vol. OTS0536975

oral-mouse LDLo 125 mg/kg
Journal of Pharmaceutical Sciences. Vol. 69, Pg. 327, 1980.

unreported-mouse LDLo 20 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: ATAXIA
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 7, Pg. 183, 1900.

intraperitoneal-rat LD50 10 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) VASCULAR: REGIONAL OR GENERAL ARTERIOLAR OR VENOUS DILATION LUNGS, THORAX, OR RESPIRATION: CYANOSIS
National Technical Information Service. Vol. OTS0536975

oral-rat LD50 50 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) SKIN AND APPENDAGES (SKIN): HAIR: OTHER BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
National Technical Information Service. Vol. OTS0536975

Dermal Toxicity:
subcutaneous-frog LDLo 2000 mg/kg
PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) CARDIAC: OTHER CHANGES
Skandinavisches Archiv fuer Physiologie. Vol. 10, Pg. 201, 1900.

subcutaneous-mouse LD50 40 mg/kg
National Technical Information Service. Vol. ORNL-5576

subcutaneous-rabbit LDLo 6 mg/kg
VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 7, Pg. 183, 1900.

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
viscosity controlling agents
Recommendation for tetramethylammonium chloride usage levels up to:
 not for fragrance use.
 
Recommendation for tetramethylammonium chloride flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
NIOSH International Chemical Safety Cards:search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):75-57-0
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :6379
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:1
tetramethylazanium;chloride
Chemidplus:0000075570
RTECS:75-57-0
 
References:
 tetramethylazanium;chloride
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:75-57-0
Pubchem (cid):6379
Pubchem (sid):134970909
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C11335
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2923.90.0000
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
 viscosity controlling agents
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 ammonium, tetramethyl-, chloride
 methanaminium, N,N,N-trimethyl-, chloride
 methanaminium, N,N,N-trimethyl-, chloride (1:1)
 tetramethyl ammonium chloride
 tetramethylazanium;chloride
 tetramine chloride
N,N,N-trimethylmethanaminium chloride
 

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Notes:
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