EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

succinic anhydride
1,4-butanedioic acid anhydride

Supplier Sponsors

Name:oxolane-2,5-dione
CAS Number: 108-30-5Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:203-570-0
FDA UNII: 6RF4O17Z8J
Nikkaji Web:J3.248D
Beilstein Number:0108441
MDL:MFCD00005525
XlogP3-AA:-0.50 (est)
Molecular Weight:100.07348000
Formula:C4 H4 O3
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:food starch-modified
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
DG SANTE Food Contact Materials:succinic anhydride
FDA Mainterm (SATF):108-30-5 ; SUCCINIC ANHYDRIDE
FDA Regulation:
FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION
Subpart I--Multipurpose Additives
Sec. 172.892 Food starch-modified.


FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS
Subpart C--Substances for Use as Components of Coatings
Sec. 175.300 Resinous and polymeric coatings.


FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS
Subpart C--Substances for Use as Components of Coatings
Sec. 175.380 Xylene-formaldehyde resins condensed with 4,4'-isopropylidenediphenol-epichlorohydrin epoxy resins.


FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS
Subpart C--Substances for Use as Components of Coatings
Sec. 175.390 Zinc-silicon dioxide matrix coatings.


FDA PART 176 -- INDIRECT FOOD ADDITIVES: PAPER AND PAPERBOARD COMPONENTS
Subpart B--Substances for Use Only as Components of Paper and Paperboard
Sec. 176.170 Components of paper and paperboard in contact with aqueous and fatty foods.


FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS
Subpart B--Substances for Use as Basic Components of Single and Repeated Use Food Contact
Sec. 177.1210 Closures with sealing gaskets for food containers.
 
Physical Properties:
Appearance:colorless needles (est)
Assay: 99.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 119.00 °C. @ 760.00 mm Hg
Boiling Point: 261.00 °C. @ 760.00 mm Hg
Vapor Pressure:0.012000 mmHg @ 25.00 °C. (est)
Flash Point: 252.00 °F. TCC ( 122.10 °C. ) (est)
logP (o/w): -0.890 (est)
Soluble in:
 water, 2.376e+004 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
Succinic anhydride >98%
Charkit Chemical
SUCCINIC ANHYDRIDE
ECSA Chemicals
SUCCINIC ANHYDRIDE
ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY
EMD Millipore
For experimental / research use only.
Succinic Anhydride
sds
Glentham Life Sciences
Succinic anhydride
Penta International
SUCCINIC ANHYDRIDE
Santa Cruz Biotechnology
For experimental / research use only.
Succinic Anhydride
Sigma-Aldrich: Aldrich
For experimental / research use only.
Succinic anhydride ≥99% (GC)
sds
SysKem Chemie
Succinic Anhydride
TCI AMERICA
For experimental / research use only.
Succinic Anhydride >95.0%(T)
sds
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 1510 mg/kg
United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. Vol. 8EHQ-0282-0433

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
food starch-modified
Recommendation for succinic anhydride usage levels up to:
 not for fragrance use.
 
Recommendation for succinic anhydride flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
NIOSH International Chemical Safety Cards:search
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
Carcinogenic Potency Database:Search
EPA GENetic TOXicology:Search
EPA Substance Registry Services (TSCA):108-30-5
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :7922
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:1
oxolane-2,5-dione
Chemidplus:0000108305
EPA/NOAA CAMEO:hazardous materials
RTECS:108-30-5
 
References:
 oxolane-2,5-dione
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:108-30-5
Pubchem (cid):7922
Pubchem (sid):134972903
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
FDA Indirect Additives used in Food Contact Substances:View
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C19524
HMDB (The Human Metabolome Database):HMDB32523
FooDB:FDB010338
Export Tariff Code:2917.19.2700
FDA Listing of Food Additive Status:View
ChemSpider:View
Wikipedia:View
EFSA Update of results on the monitoring of furan levels in food:Read Report
EFSA Previous report: Results on the monitoring of furan levels in food:Read Report
EFSA Report of the CONTAM Panel on provisional findings on furan in food:Read Report
Formulations/Preparations:
•grade: distilled. •...available in us as commercial grade containing at least 99.5% of pure chemical, with maximum of 0.5% unsaturated compound...0.15% chlorides, 0.04% sulfates...and 20 mgkg heavy metals. •flake
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 butane dioic acid anhydride
 butane dioic anhydride
1,4-butanedioic acid anhydride
 butanedioic anhydride
 dihydro-2,5-dioxofuran
 dihydro-2,5-furan dione
 dihydro-2,5-furandione
 dihydro-2,5-furanedione
2,5-dihydrofuran dione
 dihydrofuran-2,5-dione
 dihydrofurane-2,5-dione
2,5-furandione, dihydro-
oxolan-2,5-dione
 succinic acid anhydride
 succinicanhydride
 succinyl oxide
 tetrahydro-2,5-dioxofuran
 tetrahydro-2,5-furandione
 

Articles:

PubMed:Partially Hydrolyzed Bamboo (Phyllostachys heterocycla) As a Porous Bioadsorbent for the Removal of Pb(II) from Aqueous Mixtures.
PubMed:Particle-stabilizers modified from indica rice starches differing in amylose content.
PubMed:Process optimization of ultrasound-assisted curcumin nanoemulsions stabilized by OSA-modified starch.
PubMed:Structure and physicochemical properties of octenyl succinic esters of sugary maize soluble starch and waxy maize starch.
PubMed:Distribution of octenylsuccinic substituents in modified A and B polymorph starch granules.
PubMed:In vitro and in vivo digestion of octenyl succinic starch.
PubMed:The mechanism of starch granule reacted with OSA by phase transition catalyst in aqueous medium.
PubMed:Synthesis and characterization of dextrin monosuccinate.
PubMed:Effects of the order of addition of reagents and catalyst on modification of maize starches.
PubMed:Hydrophobic derivatives of guar gum hydrolyzate and gum Arabic as matrices for microencapsulation of mint oil.
PubMed:Emulsion stabilizing capacity of intact starch granules modified by heat treatment or octenyl succinic anhydride.
PubMed:Analysis of resistant starches in rat cecal contents using Fourier transform infrared photoacoustic spectroscopy.
PubMed:Quinoa starch granules as stabilizing particles for production of Pickering emulsions.
PubMed:Structure and physicochemical properties of octenyl succinic anhydride modified starches: a review.
PubMed:Quinoa starch granules: a candidate for stabilising food-grade Pickering emulsions.
PubMed:Enzyme immunoassay for tenuazonic acid in apple and tomato products.
PubMed:Structure of modified ε-polylysine micelles and their application in improving cellular antioxidant activity of curcuminoids.
PubMed:Modification of pineapple peel fibre with succinic anhydride for Cu2+, Cd2+ and Pb2+ removal from aqueous solutions.
PubMed:New (1)h NMR procedure for the characterization of native and modified food-grade starches.
PubMed:Production and physicochemical properties of 2-octen-1-ylsuccinic derivatives from waxy corn starch.
PubMed:Influence of biopolymer emulsifier type on formation and stability of rice bran oil-in-water emulsions: whey protein, gum arabic, and modified starch.
PubMed:[Studies on the characters and microstructure of enzyme and octenyl succinic anhydride modified starch].
PubMed:Functional properties of acetylated and succinylated cowpea protein concentrate and effect of enzymatic hydrolysis on solubility.
PubMed:Antioxidant activity of N-acyl chitosan oligosaccharide with same substituting degree.
PubMed:Production of monoclonal antibody to acaricide dicofol and its derivatives.
PubMed:Modification of pineapple peel fiber as metal ion adsorbent through reaction with succinic anhydride in pyridine and dimethyl sulfoxide solvents.
PubMed:Effects of acylation on the functional properties and in vitro trypsin digestibility of red kidney bean (Phaseolus vulgaris L.) protein isolate.
PubMed:Physicochemical properties of octenyl succinic anhydride-modified potato starch with different degrees of substitution.
PubMed:[Study on esterified modification of anthocyanins by FTIR].
PubMed:Synthesis and characterization of novel antimicrobial emulsifiers from epsilon-polylysine.
PubMed:Fourier transform infrared (FT-IR) microspectroscopic census of single starch granules for octenyl succinate ester modification.
PubMed:Sodium caseinates with an altered isoelectric point as emulsifiers in oil/water systems.
PubMed:Homogeneous modification of cellulose in ionic liquid with succinic anhydride using N-bromosuccinimide as a catalyst.
PubMed:Production of octenyl succinic anhydride-modified waxy corn starch and its characterization.
PubMed:[Synthesis of Sudan I artificial antigen].
PubMed:Role of lysine epsilon-amino groups of beta-lactoglobulin on its activating effect of Kluyveromyces lactis beta-galactosidase.
PubMed:Slowly digestible waxy maize starch prepared by octenyl succinic anhydride esterification and heat-moisture treatment: glycemic response and mechanism.
PubMed:Monoclonal antibody-based fluorescence polarization immunoassay for sulfamethoxypyridazine and sulfachloropyridazine.
PubMed:Flavor retention of peppermint (Mentha piperita L.) essential oil spray-dried in modified starches during encapsulation and storage.
PubMed:Adsorption of hydrophobically modified anionic starch at oppositely charged oil/water interfaces.
PubMed:Synthesis and paste properties of octenyl succinic anhydride modified early Indica rice starch.
PubMed:Quantitative description of the relation between protein net charge and protein adsorption to air-water interfaces.
PubMed:Octenyl succinic anhydride modified early indica rice starches differing in amylose content.
PubMed:Study of succinylated food proteins by Raman spectroscopy.
PubMed:Physical properties of octenyl succinic anhydride modified rice, wheat, and potato starches.
PubMed:Glycemic response to a food starch esterified by 1-octenyl succinic anhydride in humans.
PubMed:Chemically modified papain for applications in detergent formulations.
PubMed:[Development of hen's egg with low antigenicity for allergic patients].
PubMed:NTP Toxicology and Carcinogenesis Studies of Succinic Anhydride (CAS No. 108-30-5) in F344/N Rats and B6C3F1 Mice (Gavage Studies).
 
Notes:
Succinic anhydride, also called dihydro-2,5-furandione, is an organic compound with the molecular formula C4H4O3. It is the acid anhydride of succinic acid.
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