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Category:toxic natural substances
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Melting Point: | 246.00 °C. @ 760.00 mm Hg (est)
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| Boiling Point: | 569.75 °C. @ 760.00 mm Hg (est)
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| Vapor Pressure: | 1.730000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 421.00 °F. TCC ( 215.90 °C. ) (est)
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| logP (o/w): | 3.169 (est) |
| Soluble in: |
| | water, 1.44 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
intraperitoneal-chicken LD50 10 mg/kg
SKIN AND APPENDAGES (SKIN): OTHER GLANDS: OTHER
Mycopathologia. Vol. 97, Pg. 51, 1987.
oral-chicken LD50 41 mg/kg
Journal of the American College of Toxicology. Vol. 5(4), Pg. 275, 1986.
oral-mouse LD50 > 800 mg/kg
Mycopathologia et Mycologia Applicata. Vol. 35, Pg. 373, 1968.
intraperitoneal-rat LD50 60 mg/kg
KIDNEY, URETER, AND BLADDER: CHANGES PRIMARILY IN GLOMERULI
LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), DIFFUSE"
LIVER: FATTY LIVER DEGERATION
Food and Cosmetics Toxicology. Vol. 7, Pg. 135, 1969.
oral-rat LD50 120 mg/kg
LIVER: FATTY LIVER DEGERATION
LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), DIFFUSE"
KIDNEY, URETER, AND BLADDER: CHANGES PRIMARILY IN GLOMERULI
Food and Cosmetics Toxicology. Vol. 7, Pg. 135, 1969.
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | toxic natural substances |
| Recommendation for sterigmatocystin usage levels up to: | | | not for fragrance use.
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| |
| Recommendation for sterigmatocystin flavor usage levels up to: |
| | not for flavor use.
|
Safety References:
European Food Safety Authority (EFSA) reference(s):
|
Scientific Opinion on the risk for public and animal health related to the presence of sterigmatocystin in food and feed
View page or View pdf
|
Survey on sterigmatocystin in food
View page or View pdf
|
| EPI System: View |
| Chemical Carcinogenesis Research Information System:Search |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| Carcinogenic Potency Database:Search |
| EPA GENetic TOXicology:Search |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :5280389 |
| National Institute of Allergy and Infectious Diseases:Data |
| WGK Germany:3 |
| Chemidplus:0010048132 |
| RTECS:LV1750000 for cas# 10048-13-2 |
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| (3AR-cis)3a,12c- | dihydro-8-hydroxy-6-methoxy-7H-furo(3',2':4,5)furo(2,3-c)xanthen-7-one | | 7H- | furo(3',2':4,5)furo(2,3-c)xanthen-7-one, 3a,12c-dihydro-8-hydroxy-6-methoxy-, (3aR-cis)- | | 7H- | furo[3',2':4,5]furo[2, 3-c]xanthen-7-one, 3a,12c-dihydro-8-hydroxy-6-methoxy-, (3aR-cis)- | | 7H- | furo[3',2':4,5]furo[2,3-c]xanthen-7-one, 3a, 12c-dihydro-8-hydroxy-6-methoxy-, (3aR-cis)- | | 7H- | furo[3',2':4,5]furo[2,3-c]xanthen-7-one, 3a,12c-dihydro-8-hydroxy-6-methoxy-, (3aR,12cS)- | | (12cS,3aR)-8- | hydroxy-6-methoxy-12c,3a-dihydroxantheno[4',3'-5,4]furano[2,3-b]furan-7-one | | (3aR,12cS)-8- | hydroxy-6-methoxy-3a,12c-dihydro-7H-furo[3',2':4,5]furo[2,3-c]xanthen-7-one | | | sterigmatocystine |
Articles:
| PubMed:Toxigenic potentiality of Aspergillus flavus and Aspergillus parasiticus strains isolated from black pepper assessed by an LC-MS/MS based multi-mycotoxin method. |
| PubMed:Toxic indole alkaloids avrainvillamide and stephacidin B produced by a biocide tolerant indoor mold Aspergillus westerdijkiae. |
| PubMed:Fungal and bacterial metabolites associated with natural contamination of locally processed rice (Oryza sativa L.) in Nigeria. |
| PubMed:A new approach using micro HPLC-MS/MS for multi-mycotoxin analysis in maize samples. |
| PubMed:Simple and efficient methodology to determine mycotoxins in cereal syrups. |
| PubMed:Fungal and mycotoxin contamination of coffee beans in Benguet province, Philippines. |
| PubMed:The furofuran-ring selectivity, hydrogen peroxide-production and low Km value are the three elements for highly effective detoxification of aflatoxin oxidase. |
| PubMed:Public health risk associated with the co-occurrence of mycotoxins in spices consumed in Sri Lanka. |
| PubMed:Catechol formation: a novel pathway in the metabolism of sterigmatocystin and 11-methoxysterigmatocystin. |
| PubMed:Measurement of sterigmatocystin concentrations in urine for monitoring the contamination of cattle feed. |
| PubMed:Sterigmatocystin induces G1 arrest in primary human esophageal epithelial cells but induces G2 arrest in immortalized cells: key mechanistic differences in these two models. |
| PubMed:An ultra-sensitive monoclonal antibody-based competitive enzyme immunoassay for sterigmatocystin in cereal and oil products. |
| PubMed:Sterigmatocystin-induced oxidative DNA damage in human liver-derived cell line through lysosomal damage. |
| PubMed:Mycotoxins' activity at toxic and sub-toxic concentrations: differential cytotoxic and genotoxic effects of single and combined administration of sterigmatocystin, ochratoxin A and citrinin on the hepatocellular cancer cell line Hep3B. |
| PubMed:Impairment of cell cycle progression by sterigmatocystin in human pulmonary cells in vitro. |
| PubMed:Upstream regulation of mycotoxin biosynthesis. |
| PubMed:Faces of a changing climate: semi-quantitative multi-mycotoxin analysis of grain grown in exceptional climatic conditions in Norway. |
| PubMed:A new approach in sample treatment combined with UHPLC-MS/MS for the determination of multiclass mycotoxins in edible nuts and seeds. |
| PubMed:Effects of sterigmatocystin on esophageal epithelium and experimental reflux esophagitis in rats. |
| PubMed:Gβ-like CpcB plays a crucial role for growth and development of Aspergillus nidulans and Aspergillus fumigatus. |
| PubMed:Occurrence and molecular detection of toxigenic Aspergillus species in food grain samples from India. |
| PubMed:Development and validation of a QuEChERS based liquid chromatography tandem mass spectrometry method for the determination of multiple mycotoxins in spices. |
| PubMed:Sterigmatocystin-induced DNA damage triggers G2 arrest via an ATM/p53-related pathway in human gastric epithelium GES-1 cells in vitro. |
| PubMed:Stability of sterigmatocystin during the bread making process and its occurrence in bread from the Latvian market. |
| PubMed:Fungal and mycotoxin assessment of dried edible mushroom in Nigeria. |
| PubMed:Multiclass mycotoxin analysis in Silybum marianum by ultra high performance liquid chromatography-tandem mass spectrometry using a procedure based on QuEChERS and dispersive liquid-liquid microextraction. |
| PubMed:Quantitation of mycotoxins in food and feed from Burkina Faso and Mozambique using a modern LC-MS/MS multitoxin method. |
| PubMed:Effects of onion (Allium cepa L.) and garlic (Allium sativum L.) essential oils on the Aspergillus versicolor growth and sterigmatocystin production. |
| PubMed:PCR detection of aflatoxin producing fungi and its limitations. |
| PubMed:Sterigmatocystin alters the number of FoxP3+ regulatory T cells and plasmacytoid dendritic cells in BALB/c mice. |
| PubMed:Involvement of MAPK and PI3K signaling pathway in sterigmatocystin-induced G2 phase arrest in human gastric epithelium cells. |
| PubMed:Conversion of 11-hydroxy-O-methylsterigmatocystin to aflatoxin G1 in Aspergillus parasiticus. |
| PubMed:Analysis of multiple mycotoxins in beer employing (ultra)-high-resolution mass spectrometry. |
| PubMed:Analysis of multiple mycotoxins in cereals under ambient conditions using direct analysis in real time (DART) ionization coupled to high resolution mass spectrometry. |
| PubMed:Fungi on wheat bran and their toxinogenity. |
| PubMed:Sterigmatocystin: occurrence in foodstuffs and analytical methods--an overview. |
| PubMed:Occurrence of mycotoxins in feed as analyzed by a multi-mycotoxin LC-MS/MS method. |
| PubMed:[Study of specificity of fungistatic effect of trichothecene mycotoxins]. |
| PubMed:A key role for vesicles in fungal secondary metabolism. |
| PubMed:JEM Spotlight: Fungi, mycotoxins and microbial volatile organic compounds in mouldy interiors from water-damaged buildings. |
| PubMed:LC-MS/MS multi-analyte method for mycotoxin determination in food supplements. |
| PubMed:Determination of sterigmatocystin in cheese by high-performance liquid chromatography-tandem mass spectrometry. |
| PubMed:Molecular characterization of StcI esterase from Aspergillus nidulans. |
| PubMed:FvVE1 regulates biosynthesis of the mycotoxins fumonisins and fusarins in Fusarium verticillioides. |
| PubMed:[High blood and urine concentration of hepatotoxic mycotoxins (aflatoxin B1, sterigmatocystin) in patients with liver cirrhosis]. |
| PubMed:Development of a multi-mycotoxin liquid chromatography/tandem mass spectrometry method for sweet pepper analysis. |
| PubMed:Occurrence of mycotoxins in feedstuffs of dairy cows and estimation of total dietary intakes. |
| PubMed:Mycotoxins and toxigenic fungi in sago starch from Papua New Guinea. |
| PubMed:Preparation of a reference material containing sterigmatocystin. |
| PubMed:Sterigmatocystin presence in typical Latvian grains. |
| PubMed:Occurrence of mycotoxins in maize, grass and wheat silage for dairy cattle in the Netherlands. |
| PubMed:LC-MS/MS multi-method for mycotoxins after single extraction, with validation data for peanut, pistachio, wheat, maize, cornflakes, raisins and figs. |
| PubMed:Mycotoxins in rice. |
| PubMed:Analytical method for the determination of sterigmatocystin in grains using high-performance liquid chromatography-tandem mass spectrometry with electrospray positive ionization. |
| PubMed:Regulations relating to mycotoxins in food: perspectives in a global and European context. |
| PubMed:The effect of Egyptian honeybee propolis on the growth of Aspergillus versicolor and sterigmatocystin biosynthesis in Ras cheese. |
| PubMed:Fungi recovered from Slovakian poultry feed mixtures and their toxinogenity. |
| PubMed:Computer aided boar semen motility analysis for cereulide detection in different food matrices. |
| PubMed:Regulatory elements in aflatoxin biosynthesis. |
| PubMed:Heterotrimeric G protein signaling and RGSs in Aspergillus nidulans. |
| PubMed:Development of a liquid chromatography/tandem mass spectrometry method for the simultaneous determination of 16 mycotoxins on cellulose filters and in fungal cultures. |
| PubMed:The phosducin-like protein PhnA is required for Gbetagamma-mediated signaling for vegetative growth, developmental control, and toxin biosynthesis in Aspergillus nidulans. |
| PubMed:FluG-dependent asexual development in Aspergillus nidulans occurs via derepression. |
| PubMed:A novel biosensor for sterigmatocystin constructed by multi-walled carbon nanotubes (MWNT) modified with aflatoxin-detoxifizyme (ADTZ). |
| PubMed:The pkaB gene encoding the secondary protein kinase A catalytic subunit has a synthetic lethal interaction with pkaA and plays overlapping and opposite roles in Aspergillus nidulans. |
| PubMed:Regulation of secondary metabolism in filamentous fungi. |
| PubMed:Adsorption of sterigmatocystin by montmorillonite and inhibition of its genotoxicity in the Nile tilapia fish (Oreachromis nilaticus). |
| PubMed:Fungal populations and mycotoxins in silage in Assiut and Sohag governorates in Egypt, with a special reference to characteristic Aspergilli toxins. |
| PubMed:[Carcinogenic effects of sterigmatocystin and deoxynivalenol in NIH mice]. |
| PubMed:Mites and fungi in heavily infested stores in the Czech Republic. |
| PubMed:Emericella venezuelensis, a new species with stellate ascospores producing sterigmatocystin and aflatoxin B1. |
| PubMed:[Survey and analysis on sterigmatocystin contaminated in grains in China]. |
| PubMed:Regulation of aflatoxin synthesis by FadA/cAMP/protein kinase A signaling in Aspergillus parasiticus. |
| PubMed:Characterization of molds from dry-cured meat products and their metabolites by micellar electrokinetic capillary electrophoresis and random amplified polymorphic DNA PCR. |
| PubMed:[The mechanisms of gastric cancer development produced by the combination of Helicobacter pylori with Sterigmatocystin, a mycotoxin]. |
| PubMed:Ethylene modulates development and toxin biosynthesis in aspergillus possibly via an ethylene sensor-mediated signaling pathway. |
| PubMed:Enzyme reactions and genes in aflatoxin biosynthesis. |
| PubMed:[Molecular biology of aflatoxin biosynthesis]. |
| PubMed:Suppressor mutations bypass the requirement of fluG for asexual sporulation and sterigmatocystin production in Aspergillus nidulans. |
| PubMed:Mycotoxin production in wheat grains by different Aspergilli in relation to different relative humidities and storage periods. |
| PubMed:Function of native OmtA in vivo and expression and distribution of this protein in colonies of Aspergillus parasiticus. |
| PubMed:Effects of sterigmatocystin, deoxynivalenol and aflatoxin G1 on apoptosis of human peripheral blood lymphocytes in vitro. |
| PubMed:Polymerase chain reaction-mediated characterization of molds belonging to the Aspergillus flavus group and detection of Aspergillus parasiticus in peanut kernels by a multiplex polymerase chain reaction. |
| PubMed:Biology and ecology of mycotoxigenic Aspergillus species as related to economic and health concerns. |
| PubMed:Lipid peroxidation as a possible secondary mechanism of sterigmatocystin toxicity. |
| PubMed:The mycotoxin research in foodstuffs in the Czech Republic in the 90th Years. |
| PubMed:Mycotoxin production on rice, pulses and oilseeds. |
| PubMed:Cloning and characterization of the O-methyltransferase I gene (dmtA) from Aspergillus parasiticus associated with the conversions of demethylsterigmatocystin to sterigmatocystin and dihydrodemethylsterigmatocystin to dihydrosterigmatocystin in aflatoxin biosynthesis. |
| PubMed:Purification and characterization of 40-kDa sterigmatocystin O-methyltransferase involved in aflatoxin biosynthesis. |
| PubMed:Molecular biology of mycotoxin biosynthesis. |
| PubMed:A colorimetric technique for detecting trichothecenes and assessing relative potencies. |
| PubMed:DNA damage by mycotoxins. |
| PubMed:Mycotoxin production by Aspergillus, Fusarium and Penicillium species. |
| PubMed:Mycotoxins in ingredients of animal feeding stuffs: III. Determination of mycotoxins in rice bran. |
| PubMed:Mycotoxins in ingredients of animal feeding stuffs: II. Determination of mycotoxins in maize and maize products. |
| PubMed:Sterigmatocystin - incidence, fate and production byA versicolor in ras cheese. |
| PubMed:Detection of aflatoxinogenic fungi in figs by a PCR reaction. |
| PubMed:Occurrence of mycotoxins in raw ingredients used for animal feeding stuffs in the United Kingdom in 1992. |
| PubMed:Mycotoxins in fungal contaminated samples of animal feed from western Canada, 1982-1994. |
| PubMed:Sterigmatocystin: incidence, fate and production by Aspergillus versicolor in Ras cheese. |
| PubMed:Characterization of the function of the ver-1A and ver-1B genes, involved in aflatoxin biosynthesis in Aspergillus parasiticus. |
| PubMed:Mycotoxins in two Spanish cheese varieties. |
| PubMed:Analytical methods for the determination of sterigmatocystin in cheese, bread and corn products using HPLC with atmospheric pressure ionization mass spectrometric detection. |
| PubMed:[Production and characterization of sterigmatocystin]. |
| PubMed:Mycotoxins and fungi in wheat harvested during 1990 in test plots in the state of São Paulo, Brazil. |
| PubMed:[Determination of sterigmatocystin in cancerous tissues, blood and urine in patients with liver and stomach cancer]. |
| PubMed:Mycotoxins and fungi in wheat stored in elevators in the state of Rio Grande do Sul, Brazil. |
| PubMed:Incidence and abundance of mycotoxins in maize in Rio Grande do Sul, Brazil. |
| PubMed:Postharvest and stored corn in Brazil: mycoflora interaction, abiotic factors and mycotoxin occurrence. |
| PubMed:[Preparation and identification of monoclonal antibody against sterigmatocystin]. |
| PubMed:Mycotoxin-producing potential of fungi isolated from amaranth seeds in Argentina. |
| PubMed:Natural occurrence of mycotoxins in different spices in Egypt. |
| PubMed:Production and characterization of sterigmatocystin. |
| PubMed:[The diagnosis of mycotoxin hepatitis in swine]. |
| PubMed:Tumor incidence in a chemical carcinogenesis study of nonhuman primates. |
| PubMed:Direct detection using the Drosophila DNA-repair test and isolation of a DNA-damaging mycotoxin, 5,6-dihydropenicillic acid, in fungal culture. |
| PubMed:Fungal flora and mycotoxins of six kinds of nut seeds for human consumption in Saudi Arabia. |
| PubMed:Isolation, purification, toxicity and some physicochemical properties of mycotoxins produced by aspergillus quadrilineatus isolated from acha (Digitaria exilis stapf) in Plateau State of Nigeria. |
| PubMed:Mycoflora and mycotoxin of hazelnut (Corylus avellana L.) and walnut (Juglans regia L.) seeds in Egypt. |
| PubMed:Survey of mycoflora and mycotoxins of some dried fruits in Egypt. |
| PubMed:Effect of feed-borne pollution with some mycotoxin combinations on broiler chicks. |
| PubMed:Mycotoxins in foods and feeds in the United States. |
| PubMed:Solution structure of the covalent sterigmatocystin-DNA adduct. |
| PubMed:Ochratoxin A production in Bavarian cereal grains stored at 15 and 19% moisture content. |
| PubMed:Aflatoxins as risk factors for hepatocellular carcinoma in humans. |
| PubMed:The biosynthesis of polyketide-derived mycotoxins. |
| PubMed:The influence of contamination with separate mycotoxins (aflatoxins, ochratoxin A, citrinin, patulin, penicillic acid or sterigmatocystin) on the in vitro dry matter and organic matter digestibilities of some roughages (berseem hay and wheat straw). |
| PubMed:Potential natural exposure of Mississippi sandhill cranes to aflatoxin B1. |
| PubMed:Mycotoxins and mycotoxigenic moulds in nuts and sunflower seeds for human consumption. |
| PubMed:Mycotoxins: food contamination, mechanism, carcinogenic potential and preventive measures. |
| PubMed:[Mycotoxins in enzyme preparations. Part II. Method of detection and determination of sterigmatocystin]. |
| PubMed:Ochratoxin A and other mycotoxins in cereals from an area of Balkan endemic nephropathy and urinary tract tumours in Bulgaria. |
| PubMed:Aspergillus flavus and aflatoxins B1, B2, and M1 in corn associated with equine death. |
| PubMed:Mycotoxins and toxigenic fungi on cereal grains in western Canada. |
| PubMed:Minicolumn chromatography for the detection of sterigmatocystin in agricultural commodities. |
| PubMed:Survey of the mycoflora and mycotoxins of cotton seeds and cotton seed products in Egypt. |
| PubMed:Contamination of dairy products by fungal metabolites. |
| PubMed:Natural occurrence of mycotoxins in some cereals. |
| PubMed:Action of phosphine (PH3) on production of sterigmatocystin by various fungal strains isolated from foodstuffs. |
| PubMed:Mould and mycotoxin contamination of stored corn in Turkey. |
| PubMed:Immunochemical assay applied to mycotoxin biosynthesis: ELISA comparison of sterigmatocystin production by Aspergillus versicolor and Aspergillus nidulans. |
| PubMed:Human liver microsomal cytochrome P-450 enzymes involved in the bioactivation of procarcinogens detected by umu gene response in Salmonella typhimurium TA 1535/pSK1002. |
| PubMed:Mycotoxin analysis by fast atom bombardment tandem mass spectrometry. |
| PubMed:A microbiological assay for sterigmatocystin, T-2 toxin and zearalenone. |
| PubMed:Induction of hepatocellular carcinoma in nonhuman primates by chemical carcinogens. |
| PubMed:Survey of aflatoxins, ochratoxin A, zearalenone, and sterigmatocystin in some Brazilian foods by using multi-toxin thin-layer chromatographic method. |
| PubMed:Corn as a source of mycotoxins in Indonesian poultry feeds and the effectiveness of visual examination methods for detecting contamination. |
| PubMed:Production of sterigmatocystin by Aspergillus versicolor isolated from roughage. |
| PubMed:Thin-layer chromatographic determination of sterigmatocystin in cheese: interlaboratory study. |
| PubMed:Standardized high-performance liquid chromatography of 182 mycotoxins and other fungal metabolites based on alkylphenone retention indices and UV-VIS spectra (diode array detection). |
| PubMed:High-performance liquid chromatographic determination of the mycotoxins patulin, penicillic acid, zearalenone and sterigmatocystin in artificially contaminated cocoa beans. |
| PubMed:Mycotoxin formation in moist 2-row and 6-row barley during granary storage. |
| PubMed:The effects of demethylsterigmatocystin and sterigmatin on ATP synthesis system in mitochondria: A comparison with sterigmatocystin. |
| PubMed:Determination of sterigmatocystin in feed by high-performance liquid chromatography with column switching. |
| PubMed:Thin layer chromatographic determination of sterigmatocystin in cheese. |
| PubMed:Sterigmatocystin in dairy cattle feed contaminated with Aspergillus versicolor. |
| PubMed:Toxic fungal metabolites in food. |
| PubMed:Mycotoxins in cereal grain. Part XI. Simple multidetection procedure for determination of 11 mycotoxins in cereals. |
| PubMed:Chemical confirmatory tests for ochratoxin A, citrinin, penicillic acid, sterigmatocystin, and zearalenone performed directly on thin layer chromatographic plates. |
| PubMed:Mycotoxins and mycoflora in animal feedstuffs in western Canada. |
| PubMed:Mycotoxins in cereal grain. Part VII. A simple method to assay mycotoxin potential of cereal grain and cereal products. |
| PubMed:[Study of cheeses for the presence of sterigmatocystin]. |
| PubMed:The nutritional value of moldy grains for broiler chicks. |
| PubMed:High incidence of angiosarcomas in brown-fat tissue and livers of mice fed sterigmatocystin. |
| PubMed:Mycotoxin formation in moist wheat under controlled temperatures. |
| PubMed:[Detection and determination of the content of selected mycotoxins in grain]. |
| PubMed:High-performance liquid chromatography of the mycotoxin sterigmatocystin and its application to the analysis of mouldy rice for sterigmatocystin. |
| PubMed:Mycotoxins in cereal grain. Part I. Ochratoxin, citrinin, sterigmatocystin, penicillic acid and toxigenic fungi in cereal grain. |
| PubMed:[New data on the metabolism and mechanism of action of mycotoxins]. |
| PubMed:Mycotoxins in coffee. |
| PubMed:[A screening method for the determination of various mycotoxins in food (author's transl)]. |
| PubMed:Fungal growth and the presence of sterigmatocystin in hard cheese. |
| PubMed:Thin layer chromatographic method for analysis and chemical confirmation of sterigmatocystin in cheese. |
| PubMed:Toxic aspergilli from pistachio nuts. |
| PubMed:Thin layer chromatographic determination of aflatoxins, ochratoxins, sterigmatocystin, zearalenone, citrinin, T-2 toxin, diacetoxyscirpenol, penicillic acid, patulin, and penitrem A. |
| PubMed:Toxigenic fungi isolated from Roquefort cheese. |
| PubMed:[Hygienic significance of sterigmatocystin in vegetable foods. 3. Occurrence of sterigmatocystin]. |
| PubMed:[Hygienic significance of sterigmatocystin in vegetable foods. 1. Analytical detection of sterigmatocystin]. |
| PubMed:[A chromatographic method of simultaneous semi-quantitative analysis of eight mycotoxins in grain]. |
| PubMed:Mycotoxins in foodstuffs. XII. The influence of the water activity (a-w) of cakes on the growth of moulds and the formation of mycotoxins. |
| PubMed:A synergistic effect of nitrosodimethylamine on sterigmatocystin carcinogenesis in rats. |
| PubMed:High incidence of hepatic tumours in rats fed mouldy rice contaminated with Aspergillus versicolor containing sterigmatocystin. |
| PubMed:[Mycotoxins and their significance for the human and animal health]. |
| PubMed:Natural occurrence of sterigmatocystin in in-shell pecans. |
| PubMed:[Bioproduction of sterigmatocystine by Aspergillus versicolor (Vuill.) tiraboschi in dry fodder]. |
| PubMed:Fluorescence behavior of sterigmatocystin. |
| PubMed:Aflatoxin and sterigmatocystin contamination of pistachio nuts in orchards. |
| PubMed:Carcinogens occurring naturally in foods. |
| PubMed:[Mycotoxins as a cause of disease in human beings]. |
| PubMed:Prevention of the formation of mycotoxins in whole wheat bread by citric acid and lactic acid. (Mycotoxins in foodstuffs. IX). |
| PubMed:[Identification and semiquantitative determination of ochratoxins A and B, sterigmatocystin and aflatoxin B-1]. |
| PubMed:The occurrence and control of mycotoxins and mycotoxicoses. |
| PubMed:Investigation of suspected cases of mycotoxicosis in farm animals in Britain. |
| PubMed:[Marginals to mycotoxin research (author's transl)]. |
| PubMed:Biosynthesis of averufin from acetate by Aspergillus parasiticus. |
| PubMed:Mycotoxin-producing potential of mold flora of dried beans. |
| PubMed:Detection of carcinogens as mutagens: bacterial tester strains with R factor plasmids. |
| PubMed:Long-term administration of sterigmatocystin and Penicillium viridicatum to mice. |
| PubMed:Potential production of sterigmatocystin on country-cured ham. |
| PubMed:Mycotoxins (ochratoxin A, citrinin, and sterigmatocystin) and toxigenic fungi in grains and other agricultural products. |
| PubMed:Brine shrimp (Artemia salina L.) larvae as a screening system for fungal toxins. |
| PubMed:Method for analysis and chemical confirmation of sterigmatocystin. |
| PubMed:A multimycotoxin detection method for aflatoxins, ochratoxins, zearalenone, sterigmatocystin, and patulin. |
| PubMed:Carcinogenicity of sterigmatocystin. |
| PubMed:Acute toxicity of sterigmatocystin to rats. |
| PubMed:Carcinogenicity of sterigmatocystin. |
| PubMed:A method for the determination of sterigmatocystin in grain and oilseeds. |
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a carcinogenic mycotoxin produced in high yields by strains of the common molds, aspergillus versicolor, a. nidulans, and an unidentified species of bipolaris. it causes necrosis of the liver and kidney and has an inhibitory effect on orotic acid incorporation into nuclear rna. Mycotoxin of Aspergillus versicolor and Chaetomium spp.
Sterigmatocystin is a poison of the type dermatoxin, from the fungi genus Aspergillus. It appears on crusts of cheese with mold.; Sterigmatocystin is a toxic metabolite structurally closely related to the aflatoxins (compare general fact sheet number 2), and consists of a xanthone nucleus attached to a bifuran structure. Sterigmatocystin is mainly produced by the fungi Aspergillus nidulans and A. versicolor. It has been reported in mouldy grain, green coffee beans and cheese although information on its occurrence in foods is limited. It appears to occur much less frequently than the aflatoxins, although analytical methods for its determination have not been as sensitive until recently, and so it is possible that small concentrations in food commodities may not always have been detected. Although it is a potent liver carcinogen similar to aflatoxin B1, current knowledge suggests that it is nowhere near as widespread in its occurrence. If this is the true situation it would be justified to consider sterigmatocystin as no more than a risk to consumers in special or unusual circumstances. A number of closely related compounds such o-methyl sterigmatocystin are known and some may also occur naturally.; The IARC-classification of sterigmatocystin is group 2B, which means it is possibly carcinogenic to humans. In practice, the risk is quite low however, because this substance only appears on cheese crusts with mold, and because of that the chance of daily exposure is very low. A molded crust is best not to be consumed in whole, but after removing the crust, the cheese can still be consumed. Sterigmatocystin is a different kind of mold than that which appears on cheese itself, which can simply be removed before further consumption.
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3D/inchi