salicyl amide, 65-45-2

Supplier Sponsors

Best of Chemicals Supplier
Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services.
BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies.
Email:	Marketing
US Email:	Marketing
Email:	Sales
US Email:	Sales
Voice: 1-631-485-4226
Fax: 1-631-614-7828
US Voice: 1-631-485-4226
US Fax: 1-631-614-7828
Europe	44-203-286-1088
Facebook
Twitter
Linkedin
Blog
Get the App!
CODE128150 CODE128150
Product(s):
65-45-2 Hydrochlorothiazide Related Compound > 95%
Hydrochlorothiazide Related Compound is a non-prescription drug with analgesic and antipyretic properties. It is used in combination with both aspirin and caffeine in the over-the-counter pain remedy PainAid.

Penta International Corporation

Chemistry innovation
At Penta, our products and services help businesses do business better.
For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes.
US Email:	Technical Services
US Email:	Sales
US Voice: (973) 740-2300
US Fax: (973) 740-1839
CODE128150 CODE128150
Product(s):
19-05700 SALICYLAMIDE USP

TCI AMERICA

Moving Your Chemistry Forward
We continuously strive to advance our technology.
With East & West Coast distribution centers, count on TCI to deliver products quickly and reliably. Over 30,000 Reagents available today in benchtop to bulk quantities. We also offer custom synthesis solutions. Sign up for a TCI account today for fast and free shipping!
Tokyo Chemical Industry Co., Ltd. (TCI) is a leading worldwide manufacturer of specialty organic chemicals founded in 1946. TCI provides organic laboratory chemicals as well as pharmaceutical, cosmetic and functional materials. More than 70 years of synthesis experience and multi-purpose plants enable TCI to offer more than 30,000 products as well as custom synthesis.
US Email:	Sales
Email:	Technical Support
Voice: 1-800-423-8616
Fax: 1- 888-520-1075
Facebook
Twitter
Instagram
Linkedin
CODE128150 CODE128150
Product(s):
S0006 Salicylamide >98.0%(T)
SDS

Name:	2-hydroxybenzamide
CAS Number:	65-45-2	3D/inchi
ECHA EINECS - REACH Pre-Reg:	200-609-3
FDA UNII:	EM8BM710ZC
Nikkaji Web:	J1.408G
Beilstein Number:	0742439
MDL:	MFCD00007978
XlogP3:	1.30 (est)
Molecular Weight:	137.13819000
Formula:	C7 H7 N O2
BioActivity Summary:	listing
NMR Predictor:	Predict (works with chrome, Edge or firefox)

Category:cosmetic agents

US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:

Google Scholar:	Search
Google Books:	Search
Google Scholar: with word "volatile"	Search
Google Scholar: with word "flavor"	Search
Google Scholar: with word "odor"	Search
Google Patents:	Search
US Patents:	Search
EU Patents:	Search
Pubchem Patents:	Search
PubMed:	Search
NCBI:	Search
	FDA/DG SANTE Petitions, Reviews, Notices:
FCN 46	Salicylamide View - notice

Physical Properties:

Appearance:	white or slightly pink crystals (est)
Assay:	95.00 to 100.00
Food Chemicals Codex Listed:	No
Melting Point:	142.00 °C. @ 760.00 mm Hg
Boiling Point:	181.50 °C. @ 760.00 mm Hg
Flash Point:	295.00 °F. TCC ( 146.30 °C. ) (est)
logP (o/w):	1.280
Soluble in:
	water, 2060 mg/L @ 25 °C (exp)
	water, 2.64e+004 mg/L @ 25 °C (est)

Organoleptic Properties:

Odor and/or flavor descriptions from others (if found).

Cosmetic Information:

CosIng:	cosmetic data
Cosmetic Uses:	keratolytics

Suppliers:

Allan Chemical

Salicylamide

BOC Sciences

For experimental / research use only.

Hydrochlorothiazide Related Compound > 95%

Odor: characteristic

Use: Hydrochlorothiazide Related Compound is a non-prescription drug with analgesic and antipyretic properties. It is used in combination with both aspirin and caffeine in the over-the-counter pain remedy PainAid.

Sigma-Aldrich: Aldrich

For experimental / research use only.

Salicylamide 99%

sds

TCI AMERICA

For experimental / research use only.

Salicylamide >98.0%(T)

sds

Safety Information:

Preferred SDS: View

Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-cat LDLo 1000 mg/kg LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Journal of Pharmacology and Experimental Therapeutics. Vol. 101, Pg. 119, 1951. oral-cat LDLo 150 mg/kg Arzneimittel-Forschung. Drug Research. Vol. 5, Pg. 572, 1955. intraperitoneal-dog LDLo 1000 mg/kg LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Journal of Pharmacology and Experimental Therapeutics. Vol. 101, Pg. 119, 1951. oral-guinea pig LD50 1730 mg/kg BEHAVIORAL: TREMOR BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 47, Pg. 479, 1958. intraperitoneal-guinea pig LDLo 1000 mg/kg LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Journal of Pharmacology and Experimental Therapeutics. Vol. 101, Pg. 119, 1951. intraperitoneal-mouse LD50 180 mg/kg Bollettino Chimico Farmaceutico. Vol. 111, Pg. 293, 1972. intravenous-mouse LD50 313 mg/kg BEHAVIORAL: GENERAL ANESTHETIC Journal of Pharmacology and Experimental Therapeutics. Vol. 101, Pg. 119, 1951. oral-mouse LD50 300 mg/kg Arzneimittel-Forschung. Drug Research. Vol. 5, Pg. 572, 1955. oral-rabbit LD50 3200 mg/kg Arzneimittel-Forschung. Drug Research. Vol. 5, Pg. 572, 1955. intraperitoneal-rabbit LDLo 1000 mg/kg LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Journal of Pharmacology and Experimental Therapeutics. Vol. 101, Pg. 119, 1951. intraperitoneal-rat LD50 600 mg/kg Journal of Pharmacology and Experimental Therapeutics. Vol. 108, Pg. 450, 1953. oral-rat LD50 980 mg/kg LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 47, Pg. 479, 1958.
Dermal Toxicity:
subcutaneous-mouse LD50 300 mg/kg Arzneimittel-Forschung. Drug Research. Vol. 8, Pg. 25, 1958.
Inhalation Toxicity:
Not determined

Safety in Use Information:

Category:
cosmetic agents
Recommendation for salicyl amide usage levels up to:
	not for fragrance use.

Recommendation for salicyl amide flavor usage levels up to:
	not for flavor use.

Safety References:

EPI System: View

Chemical Carcinogenesis Research Information System:Search

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA Substance Registry Services (TSCA):65-45-2

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :5147

National Institute of Allergy and Infectious Diseases:Data

WGK Germany:2

2-hydroxybenzamide

Chemidplus:0000065452

EPA/NOAA CAMEO:hazardous materials

RTECS:VN6475000 for cas# 65-45-2

References:

	2-hydroxybenzamide
NIST Chemistry WebBook:	Search Inchi
Canada Domestic Sub. List:	65-45-2
Pubchem (cid):	5147
Pubchem (sid):	134972625

Other Information:

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
CHEBI:	View
CHEMBL:	View
KEGG (GenomeNet):	D01811
HMDB (The Human Metabolome Database):	Search
Export Tariff Code:	2924.21.4500
ChemSpider:	View
Wikipedia:	View
Formulations/Preparations: •salicylamide, nf capsules, 200 mg, with methapyrilene hydrochloride 50 mg & scopolamine aminoxide hydrobromide 500 ug (sominex); capsules, 324 mg, with methapyrilene hydrochloride 12 mg & scopolamine aminoxide hydrobromide 150 mg (devarex). •tablets, nf, 230 mg (amid-sal) & 600 mg (salrin); tablets, 200 mg with methapyrilene hydrochloride 25 mg (nytol); with scopolamine aminoxide hydrobromide 250 ug (sominex); tablets, 250 mg with methapyrilene hydrochloride 25 mg & scopolamine hydrobromide 200 ug (sure-sleep). •liquiprin...oral: soln 60 mgml; salamide...salicim...oral: tablets 300 mg; salrin...oral: tablets 300 & 600 mg. •grades: technical; nf.

Potential Blenders and core components note

None Found

Potential Uses:

None Found

Occurrence (nature, food, other):note

not found in nature

Synonyms:

	acket
	afko-sal
	algamon
	algiamida
	algiamide
	allevin
	amid-sal
	amidosal
	anamid
	andasol
	benesal
	benzamide, 2-hydroxy-
	benzamide, o-hydroxy-
	benzoic acid, 2-hydroxy-, amide
2-	carbamoylphenol
2-	carboxamidophenol
	cdial
	cetamide
	cymidon
	dolomide
	dropsprin
	eggosalil
	flarpirina
2-	hydroxy-benzamide
2-	hydroxybenzamide
o-	hydroxybenzamide
ortho-	hydroxybenzamide
2-	hydroxybenzoicacidamide
	liquiprin
	morsarinas
	novecyl
	oramid
	panithal
	raspberin
	rasperin
	salamide
	saliamid
	saliamin
	salicim
	salicylamide
	salicylic acid amide
	salipur
	salizell
	salrin
	salymid
	samid
	serramida
	urtosal

Articles:

PubMed:Effects of Sho-saiko-to extract and its components, Baicalin, baicalein, glycyrrhizin and glycyrrhetic acid, on pharmacokinetic behavior of salicylamide in carbon tetrachloride intoxicated rats.

PubMed:In vitro efficacy of nitro- and bromo-thiazolyl-salicylamide compounds (thiazolides) against Besnoitia besnoiti infection in Vero cells.

PubMed:Identification of metoclopramide metabolites in the urine of cattle by gas chromatography-mass spectrometry and high-performance liquid chromatography-photodiode array detection.

PubMed:Glucuronidation of morphine and six beta 2-sympathomimetics in isolated rat intestinal epithelial cells.

PubMed:Induction of tachyzoite egress from cells infected with the protozoan Neospora caninum by nitro- and bromo-thiazolides, a class of broad-spectrum anti-parasitic drugs.

PubMed:Inhibitory effects of lipophilic acids and related compounds on bacteria and mammalian cells.

Notes:

None found

salicyl amide benzamide, 2-hydroxy-

Supplier Sponsors

Articles:

salicyl amide
benzamide, 2-hydroxy-