Name: | methyl(1R,15S,17R,18R,19S,20S)-6,18-dimethoxy-17-(3,4,5-trimethoxybenzoyl)oxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate |
CAS Number: | 50-55-5 | 3D/inchi
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Other(deleted CASRN): | 1407-38-1 |
ECHA EINECS - REACH Pre-Reg: | 200-047-9 |
FDA UNII: | 8B1QWR724A |
Nikkaji Web: | J1.359E |
Beilstein Number: | 0102014 |
MDL: | MFCD00005091 |
XlogP3-AA: | 4.00 (est) |
Molecular Weight: | 608.68860000 |
Formula: | C33 H40 N2 O9 |
BioActivity Summary: | listing |
NMR Predictor: | Predict (works with chrome, Edge or firefox) |
Category:pharmaceuticals / chemical synthisis
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Appearance: | white or cream to slightly yellow crystalline powder (est) |
Assay: | 95.00 to 100.00
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Food Chemicals Codex Listed: | No |
Melting Point: | 264.50 °C. @ 760.00 mm Hg
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Boiling Point: | 700.10 °C. @ 760.00 mm Hg (est)
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Flash Point: | 711.00 °F. TCC ( 377.20 °C. ) (est)
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logP (o/w): | 4.050 (est) |
Soluble in: |
| water, 73 mg/L @ 30 °C (exp) | | water, 2.084 mg/L @ 25 °C (est) |
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
Preferred SDS: View |
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
oral-bird - wild LD50 100 mg/kg Toxicology and Applied Pharmacology. Vol. 21, Pg. 315, 1972.
intravenous-dog LD50 500 ug/kg "Drug Dosages in Laboratory Animals - A Handbook," Rev. ed., Barnes, C.D., and L.G. Eltherington, Berkeley, Univ. of California Press, 1973Vol. -, Pg. 234, 1973.
intravenous-guinea pig LDLo 16 mg/kg Arzneimittel-Forschung. Drug Research. Vol. 23, Pg. 600, 1973.
intraperitoneal-mouse LD50 5 mg/kg European Journal of Medicinal Chemistry--Chimie Therapeutique. Vol. 10, Pg. 519, 1975.
intravenous-mouse LD50 21 mg/kg GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) Arzneimittel-Forschung. Drug Research. Vol. 14, Pg. 1040, 1964.
oral-mouse LD50 > 50 mg/kg Drugs in Japan Vol. -, Pg. 1453, 1995.
intraperitoneal-rabbit LD50 7 mg/kg Journal of Drug Research. Vol. 6(3), Pg. 19, 1974.
intravenous-rabbit LD50 15 mg/kg "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 111, 1972.
intraperitoneal-rat LD50 44 mg/kg BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS Archives Internationales de Pharmacodynamie et de Therapie. Vol. 110, Pg. 20, 1957.
intravenous-rat LD50 15 mg/kg "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 111, 1972.
oral-rat LD50 420 mg/kg BEHAVIORAL: ANTIPSYCHOTIC Pesticide Science. Vol. 11, Pg. 555, 1980.
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Dermal Toxicity: |
subcutaneous-guinea pig LD50 65 mg/kg Archives Internationales de Pharmacodynamie et de Therapie. Vol. 137, Pg. 375, 1962.
subcutaneous-mouse LD50 5610 ug/kg Drugs in Japan Vol. -, Pg. 1453, 1995.
subcutaneous-rat LD50 25 mg/kg Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 56, Pg. 377, 1960.
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Category: | pharmaceuticals / chemical synthisis |
Recommendation for reserpine usage levels up to: | | not for fragrance use.
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Recommendation for reserpine flavor usage levels up to: |
| not for flavor use.
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Safety References:
EPI System: View |
ClinicalTrials.gov:search |
Daily Med:search |
Chemical Carcinogenesis Research Information System:Search |
AIDS Citations:Search |
Cancer Citations:Search |
Toxicology Citations:Search |
Carcinogenic Potency Database:Search |
EPA GENetic TOXicology:Search |
EPA Substance Registry Services (TSCA):50-55-5 |
EPA ACToR:Toxicology Data |
EPA Substance Registry Services (SRS):Registry |
Laboratory Chemical Safety Summary :5770 |
National Institute of Allergy and Infectious Diseases:Data |
WGK Germany:3 |
methyl(1R,15S,17R,18R,19S,20S)-6,18-dimethoxy-17-(3,4,5-trimethoxybenzoyl)oxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate |
Chemidplus:0000050555 |
EPA/NOAA CAMEO:hazardous materials |
RTECS:ZG0350000 for cas# 50-55-5 |
References:
| methyl(1R,15S,17R,18R,19S,20S)-6,18-dimethoxy-17-(3,4,5-trimethoxybenzoyl)oxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate |
NIST Chemistry WebBook: | Search Inchi |
Pubchem (cid): | 5770 |
Pubchem (sid): | 134971500 |
Other Information:
(IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
Videos: | The Periodic Table of Videos |
tgsc: | Atomic Weights use for this web site |
(IUPAC): | Periodic Table of the Elements |
CHEBI: | View |
CHEMBL: | View |
KEGG (GenomeNet): | C06539 |
HMDB (The Human Metabolome Database): | Search |
Export Tariff Code: | 2939.90.5000 |
MedlinePlusSupp: | View |
ChemSpider: | View |
Wikipedia: | View |
Formulations/Preparations: •reserpine (sandril, serpasil, others) is available in tablets that contain 0.1, 0.25 or 1.0 mg or in capsules that contain 0.5 mg
•dosage forms- extended-release capsules: 0.5 mg. elixir: 0.2 mg4 ml; injection: 5 mg2 ml, and 25 mg10 ml; tablets; 0.1, 0.25, 0.5, and 1 mg
•reserpine combinations: oral tablets: 0.1 mg with hydralazine hydrochloride 25 mg: serpasil, apresoline, hydrochloride #1 (with tartrazine) (ciba); 0.1 mg with hydralazine hydrochloride 25 mg and hydrochlorothiazide 15 mg: cherpas (kay), hhr (geneva generics, schein, towne), hydroserpine plus (zenith), rezide (edward), ser-a-gen (goldline) ser-ap-es (ciba), serathide (interstate), serpazide (major), tri-hydroserpine (rugby), unipres (reid-rowell).
•reserpine combinations: oral tablets: 0.1 mg with hydrochlorothiazide 25 mg: serpasil, esidrix (with tartazine) (ciba); 0.1 mg with hydrochlorothiazide 50 mg: serpasil, esidrix #2 (with tartazine) (ciba), 0.1 mg with methyclothiazide 2.5 mg: diutensen-r (wallace); 0.1 mg with trichloromethiazide: 2 mg: metatensin #2 (with tartrazine) (merrell dow); 0.1 mg with trichlormethiazide 4 mg: diurese-r (american urologicals), metatensin #4 (merrell dow), naquival (with tatazine) (schering), trichlormethanizide with resperpine tablets (bolar, moore); trichlortensin (rugby); 0.125 mg with chlorothiazide 250 mg: chloroserp-250 (quality generics), chloroserpine-250 (rugby, schein), diupres 250.
•reserpine combinations: oral tablets: 0.125 mg with chlorothiazide 500 mg: chloroserp-500 (quality generics), chloroserpine-500 (rugby, schein), diupres 500 (msd); 0.125 mg with chlorthalidone 25 mg: demi-regroton (usv); 0.125 mg with hydrochlorothiazide 25 mg: hydropres 25 (msd), hydro-reserpine-25 (interstate), hydroserp (bioline, quality generics), hydroserpine #1 (goldline, rugby, schein, zenith), hydrosine 25 mg (major), mallopress (mallard); 0.125 mg with hydrochlorothiazide 50 mg: hydropres 50 (msd), hydro-reserpine-50 (interstate), hydroserp (bioline, quality generics), hydroserpalan (lannett), hydroserpine #2 (goldline, rugby, schein, zenith), hydrosine 50 mg (major), hydrotensin-50 (mayrand).
•reserpine combinations: oral tablets: 0.125 mg with hydroflumethiazide 25 mg: hydro-fluserpine #1 (schein), hydropine (rugby), salazide-demi (major), salutensin-demi (bristol); 0.125 mg with quinethazone 50 mg: hydromox-r (lederle); 0.2 mg with hydralazine hydrochloride 50 mg: serpasil-apresoline hydrochloride #2 (with tartrazine) (ciba); 0.25 mg with chlorthalidone 50 mg: regroton (usv); 0.25 mg with polythiazide 2 mg: renese-r (pfizer).
•oral tablets: serpalan (lilly) 0.1 and 0.25 mg; serpasil (lannett) 0.1 and 0.25 mg; serpate (vale) 0.1 and 0.25 mg; 1 mg reserpine tablets (towne)
•reserpine elixir: an elixir containing reserpine and alcohol 11 to 13%.
•reserpine injection: a sterile solution of resperine in water for injections, prepared with the aid of a suitable acid.
•seominal: tablets each containing reserpine 200 ug, phenobarbitone 10 mg, and theobromine 325 mg.
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Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| apoplon | | austrapine | | benazyl | | bioserpine | | carrserp | | crystoserpine | | deserpine | | diupres | | eberpine | | elserpine | | eserpine | | gammaserpine | | helfoserpin | | hydropine | | hydropres | | hydroserpalan | | hypersine | | klimanosid | | lemiserp | | maviserpin | | mayserpine | | mephaserpin | | methyl reserpate 3,4,5-trimethoxybenzoic acid ester | | methyl(1R,15S,17R,18R,19S,20S)-6,18-dimethoxy-17-(3,4,5-trimethoxybenzoyl)oxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate | | naquival | | neoserfin | | novoreserpine | | purserpine | | rauloydin | | raumorine | | raunorine | | rausedan | | rauserpine | | rauserpol | | rausingle | | rauwasedin | | rauwipur | | regroton | | resaltex | | resedril | | reserbal | | resercen | | reserjen | | reserpal | | reserpene | | reserpin | (-)- | reserpine | | reserpine base | | reserpoid | | reserpur | | residine | | restran | | rezerpin | | rolserp | | roxinoid | | sedaraupin | | sederaupin | | serpaloid | | serpasil | | serpasol | | serpedin | | serpentil | | serpentin | | serpogen | | sertensin | | temposerpine | | tenserpinie | 3,4,5- | trimethoxybenzoyl methyl reserpate | | vio-serpine |
Articles:
PubMed:Simultaneous Determination of 10 Adulterants in Antihypertensive Functional Foods Using Multi-Walled Carbon Nanotubes-Dispersive Solid-Phase Extraction Coupled with High Performance Liquid Chromatography. |
PubMed:Extracellular dopamine and alterations on dopamine transporter are related to reserpine toxicity in Caenorhabditis elegans. |
PubMed:Benzalkonium chloride and heavy-metal tolerance in Listeria monocytogenes from retail foods. |
PubMed:Genetic determinants of antimicrobial resistance in Gram positive bacteria from organic foods. |
PubMed:Anti depressant activity of Mamsyadi Kwatha: An Ayurvedic compound formulation. |
PubMed:A review of the gastroprotective effects of ginger (Zingiber officinale Roscoe). |
PubMed:Development of antimicrobial resistance in Campylobacter jejuni and Campylobacter coli adapted to biocides. |
PubMed:Ovariectomized mouse uterotrophic assay of 36 chemicals. |
PubMed:Expression of efflux pump gene lde in ciprofloxacin-resistant foodborne isolates of Listeria monocytogenes. |
PubMed:Effect of sterilized human fecal extract on the sensitivity of Escherichia coli ATCC 25922 to enrofloxacin. |
PubMed:Listeria monocytogenes strains selected on ciprofloxacin or the disinfectant benzalkonium chloride exhibit reduced susceptibility to ciprofloxacin, gentamicin, benzalkonium chloride, and other toxic compounds. |
PubMed:Ginsenoside Rb3 exerts antidepressant-like effects in several animal models. |
PubMed:Enhanced neurodegeneration after a high dose of methamphetamine in adenosine A3 receptor null mutant mice. |
PubMed:Octopamine and occupancy: an aminergic mechanism for intruder-resident aggression in crickets. |
PubMed:Tetrabenazine, a monoamine-depleting drug used in the treatment of hyperkinetic movement disorders. |
PubMed:[Effect and mechanism of reserpine for changing salivary protein secretion in Pi-deficient rats]. |
PubMed:Effect of DOV 102,677 on the volitional consumption of ethanol by Myers' high ethanol-preferring rat. |
PubMed:High-level resistance to moxifloxacin and gatifloxacin associated with a novel mutation in gyrB in toxin-A-negative, toxin-B-positive Clostridium difficile. |
PubMed:Role of efflux pumps in adaptation and resistance of Listeria monocytogenes to benzalkonium chloride. |
PubMed:Evidence for active drug efflux in fluoroquinolone resistance in Clostridium hathewayi. |
PubMed:Identification of BCRP as transporter of benzo[a]pyrene conjugates metabolically formed in Caco-2 cells and its induction by Ah-receptor agonists. |
PubMed:Cocaine Rapid Efficacy Screening Trial (CREST): a paradigm for the controlled evaluation of candidate medications for cocaine dependence. |
PubMed:Tandem action of exercise training and food restriction completely preserves ischemic preconditioning in the aging heart. |
PubMed:Bile-mediated aminoglycoside sensitivity in Lactobacillus species likely results from increased membrane permeability attributable to cholic acid. |
PubMed:Protective effect of bovine milk whey protein concentrate on the ulcerative lesions caused by subcutaneous administration of indomethacin. |
PubMed:Evaluation of the Xpa-deficient transgenic mouse model for short-term carcinogenicity testing: 9-month studies with haloperidol, reserpine, phenacetin, and D-mannitol. |
PubMed:Antiulcer effects of amylin: a review. |
PubMed:Rat stomach ECL cells: mode of activation of histidine decarboxylase. |
PubMed:Phenotypic and genotypic characterization of food animal isolates of Salmonella with reduced sensitivity to ciprofloxacin. |
PubMed:Evaluation of the face validity of reserpine administration as an animal model of depression--Parkinson's disease association. |
PubMed:On the role of monoamine oxidase-A for the maintenance of the volitional consumption of ethanol in two different rat models. |
PubMed:Cardioprotective effect of ischemic preconditioning is preserved in food-restricted senescent rats. |
PubMed:Substance P and its transglutaminase-synthesized spermine derivative elicit yawning behavior via nitric oxide in rats. |
PubMed:Inositol reduces depressive-like behaviors in two different animal models of depression. |
PubMed:Dopamine receptor sensitive effect of dizocilpine on feeding behaviour. |
PubMed:Determination of reserpine and rescinnamine in Rauwolfia serpentina powders and tablets: collaborative study. |
PubMed:Perindopril ameliorates glomerular and renal tubulointerstitial injury in the SHR/N-corpulent rat. |
PubMed:Present and future pharmacological approaches. |
PubMed:Antinociceptive effects of neuropeptide Y and related peptides in mice. |
PubMed:Neuropharmacological studies on Fusarium toxins--II: Total toxin extract from F. oxysporum. |
PubMed:Determination of reserpine and chlorothiazide in commercial tablets by liquid chromatography with fluorescence and UV absorbance detectors in series. |
PubMed:Sympathetic nervous system influences salt appetite in four strains of rats. |
PubMed:Effect of acute administration of fish oil (omega-3 marine triglyceride) on gastric ulceration and secretion induced by various ulcerogenic and necrotizing agents in rats. |
PubMed:Determination of ajmalicine in reserpine raw materials by liquid chromatography with fluorescence detection. |
PubMed:Octopamine mediates rapid stimulation of protein kinase A in the antennal lobe of honeybees. |
PubMed:Natural substances in psychiatry (Ginkgo biloba in dementia). |
PubMed:Determination of reserpine in tablets by liquid chromatography with fluorescence detection: revised procedure. |
PubMed:Serotonin depletion inhibits feeding in carnivorous leeches (Haemopis). |
PubMed:Neural regulation of peptide YY secretion. |
PubMed:Effects of cerulein and epidermal growth factor on pancreatic growth in the reserpinized rat model. |
PubMed:The effects of blood pressure reduction on cyclosporine nephrotoxicity in the rat. |
PubMed:The effect of reserpine and stress on feeding behaviour in the light and dark phases of the diurnal cycle in rats. |
PubMed:Habituation of an appetitive reflex in the honeybee. |
PubMed:Alpha-amylase circadian rhythm of young rat parotid gland: an endogenous rhythm with maternal coordination. |
PubMed:ATP breakdown and resynthesis in the development of gastrointestinal mucosal damage and its prevention in animals and human (an overview of 25 years ulcer research studies). |
PubMed:Alterations of amylase secretion in the chronically reserpinized rat: an acetylcholine-mediated phenomenon. |
PubMed:Effects of reserpine and L-cysteine and glutathione depletion on 2-bromoethylamine hydrobromide-induced tubular necrosis in Swiss ICR mice. |
PubMed:Social isolation effects on the "behavioral despair" forced swimming test: effect of age and duration of testing. |
PubMed:The discovery of antidepressants: a winding path. |
PubMed:Evaluation of dopamine receptor involvement in rat feeding behaviour. |
PubMed:Perirenal hemorrhage syndrome in market turkey toms: effect of management factors. |
PubMed:Pharmacology, pharmacodynamics and pharmacokinetics of sotalol. |
PubMed:Alterations of pancreatic growth and of GP-2 content in the reserpinized rat model of cystic fibrosis. |
PubMed:Clearance of Pseudomonas aeruginosa in different rat lung models. |
PubMed:Protective action of SCH 12223 against experimentally induced gastric and intestinal lesions. |
PubMed:Determination of reserpine and hydrochlorothiazide in commercial tablets by liquid chromatography with fluorescence and UV absorption detectors in series. |
PubMed:Effects of reserpine treatment on dietary adaptation of the rat exocrine pancreas. |
PubMed:Changes in rat parotid saliva protein composition following chronic reserpine treatment and their relation to inanition. |
PubMed:Anorectic and behavioural effects of bupropion. |
PubMed:Progress in assessing the role of serotonin in the control of food intake. |
PubMed:5-HT1A and alpha-2 adrenergic receptors mediate the hyperglycemic and hypoinsulinemic effects of 8-hydroxy-2-(di-n-propylamino)tetralin in the conscious rat. |
PubMed:Transcallosal evoked potentials in relation to behavior in the rat: effects of atropine, p-chlorophenylalanine, reserpine, scopolamine and trifluoperazine. |
PubMed:Amphetamine and reserpine deplete brain biogenic amines and alter blow fly feeding behavior. |
PubMed:Potentiated 5-hydroxytryptophan induced response suppression in rats following chronic reserpine. |
PubMed:Beta-adrenoceptor sensitivity of brown and white adipocytes after chronic pretreatment of rats with reserpine. |
PubMed:From fenfluramine racemate to d-fenfluramine. Specificity and potency of the effects on the serotoninergic system and food intake. |
PubMed:Effects of malnutrition and chronic reserpine treatment on pancreatic exocrine function. |
PubMed:Stability of reserpine injections and tablets submitted by U.S. hospitals. |
PubMed:Effect of mealing on plasma and brain amino acid, and brain monoamine in rats after oral aspartame. |
PubMed:Toxicity and neuropharmacology of cyclopiazonic acid. |
PubMed:Effects of reserpine and adrenal demedullation on brown adipose tissue thermogenesis induced by dl-phenylpropanolamine. |
PubMed:Tolerance to or facilitation of pharmacological effects induced by chronic treatment with the beta-adrenergic stimulant clenbuterol. |
PubMed:Feeding behavior elicited by electrical stimulation of the lateral hypothalamic area in the rat: role of the adrenergic pathways and receptors. |
PubMed:Antihypertensive effects of chronic 5-hydroxytryptamine (5-HT2) receptor blockade with ketanserin in the spontaneously hypertensive rat. |
PubMed:d-Fenfluramine and salbutamol: two drugs causing anorexia through different neurochemical mechanisms. |
PubMed:Reserpine tumorigenic in rodents. |
PubMed:Effect of adrenergic blockers and depleters on food intake in rats. |
PubMed:Formation of physical dependence on barbiturates and cerebral monoamines. |
PubMed:Chronobiology and thermoregulation. |
PubMed:Influence of iproniazid on the combination effect of reserpine with antitumor agents on l1210. |
PubMed:D-Fenfluramine and D-norfenfluramine reduce food intake by acting on different serotonin mechanisms in the rat brain. |
PubMed:An improved pharmacological procedure for depletion of noradrenaline: pharmacology and assessment of noradrenaline-associated behaviors. |
PubMed:Pharmacology of amezinium, a novel antihypotensive drug. VI. Effect on central nervous functions. |
PubMed:GABA in the ventral tegmental area: differential regional effects on locomotion, aggression and food intake after microinjection of GABA agonists and antagonists. |
PubMed:Reserpine: no changes advised for now. |
PubMed:[Decrease of ACh response in isolated duodenum from SART stressed (repeated cold stressed) mice (author's transl)]. |
PubMed:Changes of interhemispheric hippocampal responses during conditioning in the awake rat. |
PubMed:Effect of reserpine on cell proliferation in the developing rat bran: a biochemical study. |
PubMed:Sympathetic inhibition of thermogenesis in the infant rat: possible glucostatic control. |
PubMed:Effect of toloxatone on behaviour of primates. |
PubMed:A hospital population of schizophrenic patients undergoing change. |
PubMed:Effect of autonomic blockers on the heart rate of intact rats and animals with artificial hyperthyroidism. |
PubMed:[Central action of WA-335-BS, a substance with peripheral antiserotonin and antihistaminic activity]. |
PubMed:Editorial: Reserpine and breast cancer: a perspective. |
PubMed:Pharmacological analysis of a new anorexic substance: 5-hydroxy-5(4'-chlorophenyl)-2, 3-dihydro-5H-imidazo-(2, 1-a) isoindole (Mazindol). |
PubMed:Circadian changes in the temperature of human beings. |
PubMed:Role of the biogenic amines in the reversal of cycloheximide-induced amnesia. |
PubMed:Effects of lesions and drugs on brain tryptamine. |
PubMed:Penicillium viridicatum mycotoxicosis in the rat. IV. Attempts to modify the tissue responses. |
PubMed:Effects of benzoquinolizine homologues on proliferative and exudative inflammation. |
PubMed:Effects of long-term reserpine treatment on brain tyrosine hydroxylase and behavioral activity. |
PubMed:Interaction of the effects of reserpine and amphetamine on food and water intake. |
PubMed:The adrenergic and cholinergic control of food and water intake. |
PubMed:Mastication, submandibular gland enlargement and the periodontal syndrome in the rice rat. |
PubMed:[On the influencing of food intake by psychotropic drugs]. |
PubMed:THE EFFECT OF RESERPINE, IPRONIAZIDE, AND BOTH IN COMBINATION ON THE FOOD-APPROACH CONDITIONED REFLEX AND BRAIN SEROTONIN LEVEL IN RATS. |
PubMed:[Oxygen consumption, body temperature, food consumption and metabolite content of the brain in white mice after reserpine administration]. |
PubMed:Federal ruling on products containing reserpine and Rauwolfia products issued by the Food and Drug Administration of the U.S. Department of Health, Education, and Welfare. |
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