EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

reserpine
methyl reserpate 3,4,5-trimethoxybenzoic acid ester

Supplier Sponsors

Name:methyl(1R,15S,17R,18R,19S,20S)-6,18-dimethoxy-17-(3,4,5-trimethoxybenzoyl)oxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate
CAS Number: 50-55-5Picture of molecule3D/inchi
Other(deleted CASRN):1407-38-1
ECHA EINECS - REACH Pre-Reg:200-047-9
FDA UNII: 8B1QWR724A
Nikkaji Web:J1.359E
Beilstein Number:0102014
MDL:MFCD00005091
XlogP3-AA:4.00 (est)
Molecular Weight:608.68860000
Formula:C33 H40 N2 O9
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:pharmaceuticals / chemical synthisis
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Appearance:white or cream to slightly yellow crystalline powder (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 264.50 °C. @ 760.00 mm Hg
Boiling Point: 700.10 °C. @ 760.00 mm Hg (est)
Flash Point: 711.00 °F. TCC ( 377.20 °C. ) (est)
logP (o/w): 4.050 (est)
Soluble in:
 water, 73 mg/L @ 30 °C (exp)
 water, 2.084 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Alfa Biotechnology
For experimental / research use only.
Reserpine 98%
BOC Sciences
For experimental / research use only.
Reserpine >98%
Odor: characteristic
Use: Reserpine is an inhibitor of multidrug efflux pumps, used as an antipsychotic and antihypertensive drug.
Santa Cruz Biotechnology
For experimental / research use only.
Reserpine ≥98%
Sigma-Aldrich: Sigma
For experimental / research use only.
Reserpine
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-bird - wild LD50 100 mg/kg
Toxicology and Applied Pharmacology. Vol. 21, Pg. 315, 1972.

intravenous-dog LD50 500 ug/kg
"Drug Dosages in Laboratory Animals - A Handbook," Rev. ed., Barnes, C.D., and L.G. Eltherington, Berkeley, Univ. of California Press, 1973Vol. -, Pg. 234, 1973.

intravenous-guinea pig LDLo 16 mg/kg
Arzneimittel-Forschung. Drug Research. Vol. 23, Pg. 600, 1973.

intraperitoneal-mouse LD50 5 mg/kg
European Journal of Medicinal Chemistry--Chimie Therapeutique. Vol. 10, Pg. 519, 1975.

intravenous-mouse LD50 21 mg/kg
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
Arzneimittel-Forschung. Drug Research. Vol. 14, Pg. 1040, 1964.

oral-mouse LD50 > 50 mg/kg
Drugs in Japan Vol. -, Pg. 1453, 1995.

intraperitoneal-rabbit LD50 7 mg/kg
Journal of Drug Research. Vol. 6(3), Pg. 19, 1974.

intravenous-rabbit LD50 15 mg/kg
"Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 111, 1972.

intraperitoneal-rat LD50 44 mg/kg
BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 110, Pg. 20, 1957.

intravenous-rat LD50 15 mg/kg
"Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 111, 1972.

oral-rat LD50 420 mg/kg
BEHAVIORAL: ANTIPSYCHOTIC
Pesticide Science. Vol. 11, Pg. 555, 1980.

Dermal Toxicity:
subcutaneous-guinea pig LD50 65 mg/kg
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 137, Pg. 375, 1962.

subcutaneous-mouse LD50 5610 ug/kg
Drugs in Japan Vol. -, Pg. 1453, 1995.

subcutaneous-rat LD50 25 mg/kg
Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 56, Pg. 377, 1960.

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
pharmaceuticals / chemical synthisis
Recommendation for reserpine usage levels up to:
 not for fragrance use.
 
Recommendation for reserpine flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
ClinicalTrials.gov:search
Daily Med:search
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
Carcinogenic Potency Database:Search
EPA GENetic TOXicology:Search
EPA Substance Registry Services (TSCA):50-55-5
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :5770
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
methyl(1R,15S,17R,18R,19S,20S)-6,18-dimethoxy-17-(3,4,5-trimethoxybenzoyl)oxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate
Chemidplus:0000050555
EPA/NOAA CAMEO:hazardous materials
RTECS:ZG0350000 for cas# 50-55-5
 
References:
 methyl(1R,15S,17R,18R,19S,20S)-6,18-dimethoxy-17-(3,4,5-trimethoxybenzoyl)oxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):5770
Pubchem (sid):134971500
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C06539
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2939.90.5000
MedlinePlusSupp:View
ChemSpider:View
Wikipedia:View
Formulations/Preparations:
•reserpine (sandril, serpasil, others) is available in tablets that contain 0.1, 0.25 or 1.0 mg or in capsules that contain 0.5 mg •dosage forms- extended-release capsules: 0.5 mg. elixir: 0.2 mg4 ml; injection: 5 mg2 ml, and 25 mg10 ml; tablets; 0.1, 0.25, 0.5, and 1 mg •reserpine combinations: oral tablets: 0.1 mg with hydralazine hydrochloride 25 mg: serpasil, apresoline, hydrochloride #1 (with tartrazine) (ciba); 0.1 mg with hydralazine hydrochloride 25 mg and hydrochlorothiazide 15 mg: cherpas (kay), hhr (geneva generics, schein, towne), hydroserpine plus (zenith), rezide (edward), ser-a-gen (goldline) ser-ap-es (ciba), serathide (interstate), serpazide (major), tri-hydroserpine (rugby), unipres (reid-rowell). •reserpine combinations: oral tablets: 0.1 mg with hydrochlorothiazide 25 mg: serpasil, esidrix (with tartazine) (ciba); 0.1 mg with hydrochlorothiazide 50 mg: serpasil, esidrix #2 (with tartazine) (ciba), 0.1 mg with methyclothiazide 2.5 mg: diutensen-r (wallace); 0.1 mg with trichloromethiazide: 2 mg: metatensin #2 (with tartrazine) (merrell dow); 0.1 mg with trichlormethiazide 4 mg: diurese-r (american urologicals), metatensin #4 (merrell dow), naquival (with tatazine) (schering), trichlormethanizide with resperpine tablets (bolar, moore); trichlortensin (rugby); 0.125 mg with chlorothiazide 250 mg: chloroserp-250 (quality generics), chloroserpine-250 (rugby, schein), diupres 250. •reserpine combinations: oral tablets: 0.125 mg with chlorothiazide 500 mg: chloroserp-500 (quality generics), chloroserpine-500 (rugby, schein), diupres 500 (msd); 0.125 mg with chlorthalidone 25 mg: demi-regroton (usv); 0.125 mg with hydrochlorothiazide 25 mg: hydropres 25 (msd), hydro-reserpine-25 (interstate), hydroserp (bioline, quality generics), hydroserpine #1 (goldline, rugby, schein, zenith), hydrosine 25 mg (major), mallopress (mallard); 0.125 mg with hydrochlorothiazide 50 mg: hydropres 50 (msd), hydro-reserpine-50 (interstate), hydroserp (bioline, quality generics), hydroserpalan (lannett), hydroserpine #2 (goldline, rugby, schein, zenith), hydrosine 50 mg (major), hydrotensin-50 (mayrand). •reserpine combinations: oral tablets: 0.125 mg with hydroflumethiazide 25 mg: hydro-fluserpine #1 (schein), hydropine (rugby), salazide-demi (major), salutensin-demi (bristol); 0.125 mg with quinethazone 50 mg: hydromox-r (lederle); 0.2 mg with hydralazine hydrochloride 50 mg: serpasil-apresoline hydrochloride #2 (with tartrazine) (ciba); 0.25 mg with chlorthalidone 50 mg: regroton (usv); 0.25 mg with polythiazide 2 mg: renese-r (pfizer). •oral tablets: serpalan (lilly) 0.1 and 0.25 mg; serpasil (lannett) 0.1 and 0.25 mg; serpate (vale) 0.1 and 0.25 mg; 1 mg reserpine tablets (towne) •reserpine elixir: an elixir containing reserpine and alcohol 11 to 13%. •reserpine injection: a sterile solution of resperine in water for injections, prepared with the aid of a suitable acid. •seominal: tablets each containing reserpine 200 ug, phenobarbitone 10 mg, and theobromine 325 mg.
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 apoplon
 austrapine
 benazyl
 bioserpine
 carrserp
 crystoserpine
 deserpine
 diupres
 eberpine
 elserpine
 eserpine
 gammaserpine
 helfoserpin
 hydropine
 hydropres
 hydroserpalan
 hypersine
 klimanosid
 lemiserp
 maviserpin
 mayserpine
 mephaserpin
 methyl reserpate 3,4,5-trimethoxybenzoic acid ester
 methyl(1R,15S,17R,18R,19S,20S)-6,18-dimethoxy-17-(3,4,5-trimethoxybenzoyl)oxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate
 naquival
 neoserfin
 novoreserpine
 purserpine
 rauloydin
 raumorine
 raunorine
 rausedan
 rauserpine
 rauserpol
 rausingle
 rauwasedin
 rauwipur
 regroton
 resaltex
 resedril
 reserbal
 resercen
 reserjen
 reserpal
 reserpene
 reserpin
(-)-reserpine
 reserpine base
 reserpoid
 reserpur
 residine
 restran
 rezerpin
 rolserp
 roxinoid
 sedaraupin
 sederaupin
 serpaloid
 serpasil
 serpasol
 serpedin
 serpentil
 serpentin
 serpogen
 sertensin
 temposerpine
 tenserpinie
3,4,5-trimethoxybenzoyl methyl reserpate
 vio-serpine
 

Articles:

PubMed:Simultaneous Determination of 10 Adulterants in Antihypertensive Functional Foods Using Multi-Walled Carbon Nanotubes-Dispersive Solid-Phase Extraction Coupled with High Performance Liquid Chromatography.
PubMed:Extracellular dopamine and alterations on dopamine transporter are related to reserpine toxicity in Caenorhabditis elegans.
PubMed:Benzalkonium chloride and heavy-metal tolerance in Listeria monocytogenes from retail foods.
PubMed:Genetic determinants of antimicrobial resistance in Gram positive bacteria from organic foods.
PubMed:Anti depressant activity of Mamsyadi Kwatha: An Ayurvedic compound formulation.
PubMed:A review of the gastroprotective effects of ginger (Zingiber officinale Roscoe).
PubMed:Development of antimicrobial resistance in Campylobacter jejuni and Campylobacter coli adapted to biocides.
PubMed:Ovariectomized mouse uterotrophic assay of 36 chemicals.
PubMed:Expression of efflux pump gene lde in ciprofloxacin-resistant foodborne isolates of Listeria monocytogenes.
PubMed:Effect of sterilized human fecal extract on the sensitivity of Escherichia coli ATCC 25922 to enrofloxacin.
PubMed:Listeria monocytogenes strains selected on ciprofloxacin or the disinfectant benzalkonium chloride exhibit reduced susceptibility to ciprofloxacin, gentamicin, benzalkonium chloride, and other toxic compounds.
PubMed:Ginsenoside Rb3 exerts antidepressant-like effects in several animal models.
PubMed:Enhanced neurodegeneration after a high dose of methamphetamine in adenosine A3 receptor null mutant mice.
PubMed:Octopamine and occupancy: an aminergic mechanism for intruder-resident aggression in crickets.
PubMed:Tetrabenazine, a monoamine-depleting drug used in the treatment of hyperkinetic movement disorders.
PubMed:[Effect and mechanism of reserpine for changing salivary protein secretion in Pi-deficient rats].
PubMed:Effect of DOV 102,677 on the volitional consumption of ethanol by Myers' high ethanol-preferring rat.
PubMed:High-level resistance to moxifloxacin and gatifloxacin associated with a novel mutation in gyrB in toxin-A-negative, toxin-B-positive Clostridium difficile.
PubMed:Role of efflux pumps in adaptation and resistance of Listeria monocytogenes to benzalkonium chloride.
PubMed:Evidence for active drug efflux in fluoroquinolone resistance in Clostridium hathewayi.
PubMed:Identification of BCRP as transporter of benzo[a]pyrene conjugates metabolically formed in Caco-2 cells and its induction by Ah-receptor agonists.
PubMed:Cocaine Rapid Efficacy Screening Trial (CREST): a paradigm for the controlled evaluation of candidate medications for cocaine dependence.
PubMed:Tandem action of exercise training and food restriction completely preserves ischemic preconditioning in the aging heart.
PubMed:Bile-mediated aminoglycoside sensitivity in Lactobacillus species likely results from increased membrane permeability attributable to cholic acid.
PubMed:Protective effect of bovine milk whey protein concentrate on the ulcerative lesions caused by subcutaneous administration of indomethacin.
PubMed:Evaluation of the Xpa-deficient transgenic mouse model for short-term carcinogenicity testing: 9-month studies with haloperidol, reserpine, phenacetin, and D-mannitol.
PubMed:Antiulcer effects of amylin: a review.
PubMed:Rat stomach ECL cells: mode of activation of histidine decarboxylase.
PubMed:Phenotypic and genotypic characterization of food animal isolates of Salmonella with reduced sensitivity to ciprofloxacin.
PubMed:Evaluation of the face validity of reserpine administration as an animal model of depression--Parkinson's disease association.
PubMed:On the role of monoamine oxidase-A for the maintenance of the volitional consumption of ethanol in two different rat models.
PubMed:Cardioprotective effect of ischemic preconditioning is preserved in food-restricted senescent rats.
PubMed:Substance P and its transglutaminase-synthesized spermine derivative elicit yawning behavior via nitric oxide in rats.
PubMed:Inositol reduces depressive-like behaviors in two different animal models of depression.
PubMed:Dopamine receptor sensitive effect of dizocilpine on feeding behaviour.
PubMed:Determination of reserpine and rescinnamine in Rauwolfia serpentina powders and tablets: collaborative study.
PubMed:Perindopril ameliorates glomerular and renal tubulointerstitial injury in the SHR/N-corpulent rat.
PubMed:Present and future pharmacological approaches.
PubMed:Antinociceptive effects of neuropeptide Y and related peptides in mice.
PubMed:Neuropharmacological studies on Fusarium toxins--II: Total toxin extract from F. oxysporum.
PubMed:Determination of reserpine and chlorothiazide in commercial tablets by liquid chromatography with fluorescence and UV absorbance detectors in series.
PubMed:Sympathetic nervous system influences salt appetite in four strains of rats.
PubMed:Effect of acute administration of fish oil (omega-3 marine triglyceride) on gastric ulceration and secretion induced by various ulcerogenic and necrotizing agents in rats.
PubMed:Determination of ajmalicine in reserpine raw materials by liquid chromatography with fluorescence detection.
PubMed:Octopamine mediates rapid stimulation of protein kinase A in the antennal lobe of honeybees.
PubMed:Natural substances in psychiatry (Ginkgo biloba in dementia).
PubMed:Determination of reserpine in tablets by liquid chromatography with fluorescence detection: revised procedure.
PubMed:Serotonin depletion inhibits feeding in carnivorous leeches (Haemopis).
PubMed:Neural regulation of peptide YY secretion.
PubMed:Effects of cerulein and epidermal growth factor on pancreatic growth in the reserpinized rat model.
PubMed:The effects of blood pressure reduction on cyclosporine nephrotoxicity in the rat.
PubMed:The effect of reserpine and stress on feeding behaviour in the light and dark phases of the diurnal cycle in rats.
PubMed:Habituation of an appetitive reflex in the honeybee.
PubMed:Alpha-amylase circadian rhythm of young rat parotid gland: an endogenous rhythm with maternal coordination.
PubMed:ATP breakdown and resynthesis in the development of gastrointestinal mucosal damage and its prevention in animals and human (an overview of 25 years ulcer research studies).
PubMed:Alterations of amylase secretion in the chronically reserpinized rat: an acetylcholine-mediated phenomenon.
PubMed:Effects of reserpine and L-cysteine and glutathione depletion on 2-bromoethylamine hydrobromide-induced tubular necrosis in Swiss ICR mice.
PubMed:Social isolation effects on the "behavioral despair" forced swimming test: effect of age and duration of testing.
PubMed:The discovery of antidepressants: a winding path.
PubMed:Evaluation of dopamine receptor involvement in rat feeding behaviour.
PubMed:Perirenal hemorrhage syndrome in market turkey toms: effect of management factors.
PubMed:Pharmacology, pharmacodynamics and pharmacokinetics of sotalol.
PubMed:Alterations of pancreatic growth and of GP-2 content in the reserpinized rat model of cystic fibrosis.
PubMed:Clearance of Pseudomonas aeruginosa in different rat lung models.
PubMed:Protective action of SCH 12223 against experimentally induced gastric and intestinal lesions.
PubMed:Determination of reserpine and hydrochlorothiazide in commercial tablets by liquid chromatography with fluorescence and UV absorption detectors in series.
PubMed:Effects of reserpine treatment on dietary adaptation of the rat exocrine pancreas.
PubMed:Changes in rat parotid saliva protein composition following chronic reserpine treatment and their relation to inanition.
PubMed:Anorectic and behavioural effects of bupropion.
PubMed:Progress in assessing the role of serotonin in the control of food intake.
PubMed:5-HT1A and alpha-2 adrenergic receptors mediate the hyperglycemic and hypoinsulinemic effects of 8-hydroxy-2-(di-n-propylamino)tetralin in the conscious rat.
PubMed:Transcallosal evoked potentials in relation to behavior in the rat: effects of atropine, p-chlorophenylalanine, reserpine, scopolamine and trifluoperazine.
PubMed:Amphetamine and reserpine deplete brain biogenic amines and alter blow fly feeding behavior.
PubMed:Potentiated 5-hydroxytryptophan induced response suppression in rats following chronic reserpine.
PubMed:Beta-adrenoceptor sensitivity of brown and white adipocytes after chronic pretreatment of rats with reserpine.
PubMed:From fenfluramine racemate to d-fenfluramine. Specificity and potency of the effects on the serotoninergic system and food intake.
PubMed:Effects of malnutrition and chronic reserpine treatment on pancreatic exocrine function.
PubMed:Stability of reserpine injections and tablets submitted by U.S. hospitals.
PubMed:Effect of mealing on plasma and brain amino acid, and brain monoamine in rats after oral aspartame.
PubMed:Toxicity and neuropharmacology of cyclopiazonic acid.
PubMed:Effects of reserpine and adrenal demedullation on brown adipose tissue thermogenesis induced by dl-phenylpropanolamine.
PubMed:Tolerance to or facilitation of pharmacological effects induced by chronic treatment with the beta-adrenergic stimulant clenbuterol.
PubMed:Feeding behavior elicited by electrical stimulation of the lateral hypothalamic area in the rat: role of the adrenergic pathways and receptors.
PubMed:Antihypertensive effects of chronic 5-hydroxytryptamine (5-HT2) receptor blockade with ketanserin in the spontaneously hypertensive rat.
PubMed:d-Fenfluramine and salbutamol: two drugs causing anorexia through different neurochemical mechanisms.
PubMed:Reserpine tumorigenic in rodents.
PubMed:Effect of adrenergic blockers and depleters on food intake in rats.
PubMed:Formation of physical dependence on barbiturates and cerebral monoamines.
PubMed:Chronobiology and thermoregulation.
PubMed:Influence of iproniazid on the combination effect of reserpine with antitumor agents on l1210.
PubMed:D-Fenfluramine and D-norfenfluramine reduce food intake by acting on different serotonin mechanisms in the rat brain.
PubMed:An improved pharmacological procedure for depletion of noradrenaline: pharmacology and assessment of noradrenaline-associated behaviors.
PubMed:Pharmacology of amezinium, a novel antihypotensive drug. VI. Effect on central nervous functions.
PubMed:GABA in the ventral tegmental area: differential regional effects on locomotion, aggression and food intake after microinjection of GABA agonists and antagonists.
PubMed:Reserpine: no changes advised for now.
PubMed:[Decrease of ACh response in isolated duodenum from SART stressed (repeated cold stressed) mice (author's transl)].
PubMed:Changes of interhemispheric hippocampal responses during conditioning in the awake rat.
PubMed:Effect of reserpine on cell proliferation in the developing rat bran: a biochemical study.
PubMed:Sympathetic inhibition of thermogenesis in the infant rat: possible glucostatic control.
PubMed:Effect of toloxatone on behaviour of primates.
PubMed:A hospital population of schizophrenic patients undergoing change.
PubMed:Effect of autonomic blockers on the heart rate of intact rats and animals with artificial hyperthyroidism.
PubMed:[Central action of WA-335-BS, a substance with peripheral antiserotonin and antihistaminic activity].
PubMed:Editorial: Reserpine and breast cancer: a perspective.
PubMed:Pharmacological analysis of a new anorexic substance: 5-hydroxy-5(4'-chlorophenyl)-2, 3-dihydro-5H-imidazo-(2, 1-a) isoindole (Mazindol).
PubMed:Circadian changes in the temperature of human beings.
PubMed:Role of the biogenic amines in the reversal of cycloheximide-induced amnesia.
PubMed:Effects of lesions and drugs on brain tryptamine.
PubMed:Penicillium viridicatum mycotoxicosis in the rat. IV. Attempts to modify the tissue responses.
PubMed:Effects of benzoquinolizine homologues on proliferative and exudative inflammation.
PubMed:Effects of long-term reserpine treatment on brain tyrosine hydroxylase and behavioral activity.
PubMed:Interaction of the effects of reserpine and amphetamine on food and water intake.
PubMed:The adrenergic and cholinergic control of food and water intake.
PubMed:Mastication, submandibular gland enlargement and the periodontal syndrome in the rice rat.
PubMed:[On the influencing of food intake by psychotropic drugs].
PubMed:THE EFFECT OF RESERPINE, IPRONIAZIDE, AND BOTH IN COMBINATION ON THE FOOD-APPROACH CONDITIONED REFLEX AND BRAIN SEROTONIN LEVEL IN RATS.
PubMed:[Oxygen consumption, body temperature, food consumption and metabolite content of the brain in white mice after reserpine administration].
PubMed:Federal ruling on products containing reserpine and Rauwolfia products issued by the Food and Drug Administration of the U.S. Department of Health, Education, and Welfare.
 
Notes:
an alkaloid found in the roots of rauwolfia serpentina and r. vomitoria. reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. it has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
Please share your Comments.
Email Address:
Top of Page Home
Copyright © 1980-2021 The Good Scents Company (tgsc) ™ Disclaimer Privacy Policy