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Category:natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Melting Point: | 274.50 °C. @ 760.00 mm Hg
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| Boiling Point: | 653.00 °C. @ 760.00 mm Hg (est)
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| Flash Point: | 685.00 °F. TCC ( 362.70 °C. ) (est)
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| logP (o/w): | 2.050 (est) |
| Soluble in: |
| | water, 3433 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | natural substances and extractives |
| Recommendation for purpurogallin usage levels up to: | | | not for fragrance use.
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| Recommendation for purpurogallin flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 5H- | benzocyclohepten-5-one, 2,3,4,6-tetrahydroxy- | | | purpurogalline | | 2,3,4,6- | tetrahydroxy-5H-benzo[7]annulen-5-one | | 2,3,4,6- | tetrahydroxy-5H-benzo[a]cyclohepten-5-one | | 2,3,4,6- | tetrahydroxy-5H-benzocyclohepten-5-one | | 2,3,4,6- | tetrahydroxy-5H-benzocycloheptene-5-one | | 2,3,4,6- | tetrahydroxy-benzocyclohepten-5-one | | 2,3,4,6- | tetrahydroxybenzo[7]annulen-6-one | | 2,7,8,9- | tetrahydroxybenzo[a][7]annulen-1-one | | 2,3,4,6- | tetrahydroxybenzocyclohepten-5-one |
Articles:
| PubMed:Purpurogallin, a natural phenol, attenuates high-mobility group box 1 in subarachnoid hemorrhage induced vasospasm in a rat model. |
| PubMed:New insights of superoxide dismutase inhibition of pyrogallol autoxidation. |
| PubMed:Theaflavins enhance intestinal barrier of Caco-2 Cell monolayers through the expression of AMP-activated protein kinase-mediated Occludin, Claudin-1, and ZO-1. |
| PubMed:Antiplatelet and antithrombotic activities of purpurogallin in vitro and in vivo. |
| PubMed:Purpurogallin exerts anti‑inflammatory effects in lipopolysaccharide‑stimulated BV2 microglial cells through the inactivation of the NF‑κB and MAPK signaling pathways. |
| PubMed:[Targeting the substrate binding domain of polo-like kinase 1: advances in the study of PBD1 inhibitors]. |
| PubMed:Spectrophotometric determination of sulfide based on peroxidase inhibition by detection of purpurogallin formation. |
| PubMed:Synthesis and evaluation as potential anticancer agents of novel tetracyclic indenoquinoline derivatives. |
| PubMed:Anti-inflammatory functions of purpurogallin in LPS-activated human endothelial cells. |
| PubMed:Characterization of an UV- and VIS-absorbing, purpurogallin-derived secondary pigment new to algae and highly abundant in Mesotaenium berggrenii (Zygnematophyceae, Chlorophyta), an extremophyte living on glaciers. |
| PubMed:Triterpene hexahydroxydiphenoyl esters and a quinic acid purpurogallin carbonyl ester from the leaves of Castanopsis fissa. |
| PubMed:A graphene oxide/hemoglobin composite hydrogel for enzymatic catalysis in organic solvents. |
| PubMed:Natural products in regression and slowing of progression of atherosclerosis. |
| PubMed:Exploring Potential Binding Modes of Small Drug-like Molecules to the Polo-Box Domain of Human Polo-like Kinase 1. |
| PubMed:Hybrid inorganic/organic alumina adsorbents-functionalized-purpurogallin for removal and preconcentration of Cr(III), Fe(III), Cu(II), Cd(II) and Pb(II) from underground water. |
| PubMed:Biocatalysis in water-in-ionic liquid microemulsions: a case study with horseradish peroxidase. |
| PubMed:Deficiency in chromosome congression by the inhibition of Plk1 polo box domain-dependent recognition. |
| PubMed:Flow-injection chemiluminescent determination of vanadium(IV) and total vanadium by means of catalysis on the periodate oxidation of purpurogallin. |
| PubMed:Cytotoxicity of chloroquine in isolated rat hepatocytes. |
| PubMed:Peroxidase activity can dictate the in vitro lignin dehydrogenative polymer structure. |
| PubMed:Potent inhibitory effects of black tea theaflavins on off-odor formation from citral. |
| PubMed:Protection by tropolones against H2O2-induced DNA damage and apoptosis in cultured Jurkat cells. |
| PubMed:Benzotropolone inhibitors of estradiol methylation: kinetics and in silico modeling studies. |
| PubMed:[Separation and identification of two benzotropolones from teapigment]. |
| PubMed:Metabolism of pyrogallol to purpurogallin by human erythrocytic hemoglobin. |
| PubMed:A mesh microcontactor for 2-phase reactions. |
| PubMed:Coordination of aluminium with purpurogallin and theaflavin digallate. |
| PubMed:Discovery, characterization, and structure-activity relationships studies of proapoptotic polyphenols targeting B-cell lymphocyte/leukemia-2 proteins. |
| PubMed:Design, synthesis, and biological evaluation of a series of simple and novel potential antimalarial compounds. |
| PubMed:Chemiluminescent detection of catecholamines by generation of hydrogen peroxide with imidazole. |
| PubMed:Inhibition of oncogene product enzyme activity as an approach to cancer chemoprevention. Tyrosine-specific protein kinase inhibition by purpurogallin from Quercus sp. nutgall. |
| PubMed:Ethanol's effect on rat pituitary adrenal axis is prevented by purine metabolic pathway inhibitors. |
| PubMed:Human immunodeficiency virus type 1 cDNA integration: new aromatic hydroxylated inhibitors and studies of the inhibition mechanism. |
| PubMed:Flow injection determination of free and total cholesterol in animal greases using enzymes in non-aqueous media. |
| PubMed:Inhibition of xanthine oxidase by purpurogallin and silymarin group. |
| PubMed:Morin hydrate: a better protector than purpurogallin of corneal endothelial cell damage induced by xanthine oxidase and SIN-1. |
| PubMed:Biological activity of purpurogallin. |
| PubMed:Negative ion electrospray mass spectrometry of polyphenols, catecholamines and their oxidation products. |
| PubMed:Molecular structure and antioxidant specificity of purpurogallin in three types of human cardiovascular cells. |
| PubMed:Purpurogallin inhibits DNA synthesis of murine fibrosarcoma L-929 and human U-87 MG glioblastoma cells in vitro. |
| PubMed:Novel inhibitors of 3-phosphoglycerate kinase. |
| PubMed:Detection of substances with alcoholic or phenolic hydroxyl groups by generation of hydrogen peroxide with imidazole and peroxyoxalate chemiluminescence. |
| PubMed:Comparative cytoprotection of cultured corneal endothelial cells by water-soluble antioxidants against free-radical damage. |
| PubMed:New enhancers for the chemiluminescent peroxidase catalysed chemiluminescent oxidation of pyrogallol and purpurogallin. |
| PubMed:Molecular mechanisms of tirapazamine (SR 4233, Win 59075)-induced hepatocyte toxicity under low oxygen concentrations. |
| PubMed:Comparative antioxidant protection of cultured rabbit corneal epithelium. |
| PubMed:Purpurogallin, a scavenger of polymorphonuclear leukocyte-derived oxyradicals. |
| PubMed:Purpurogallin as a cytoprotector of cultured rabbit corneal endothelium. |
| PubMed:Evaluation of hydroxyl radical-scavenging property of purpurogallin using high pressure liquid chromatography. |
| PubMed:Purpurogallin: in vivo evidence of a novel and effective cardioprotector. |
| PubMed:Purpurogallin as an antioxidant protector of human erythrocytes against lysis by peroxyl radicals. |
| PubMed:Effects of phenol compounds, glutathione analogues and a diuretic drug on glutathione S-transferase, glutathione reductase and glutathione peroxidase from canine erythrocytes. |
| PubMed:Purpurogallin protects both ventricular myocytes and aortic endothelial cells of rats against oxyradical damage. |
| PubMed:Purpurogallin is a more powerful protector of kidney cells than Trolox and allopurinol. |
| PubMed:Purpurogallin--a natural and effective hepatoprotector in vitro and in vivo. |
| PubMed:Block copolymer microdomains: a novel medium for enzymatic reactions. |
| PubMed:Kinetics and inhibition studies of catechol O-methyltransferase from the yeast Candida tropicalis. |
| PubMed:Differential inhibition of rat and human glutathione S-transferase isoenzymes by plant phenols. |
| PubMed:[Chemiluminescence immunoenzyme technic for detection of small numbers of bacteria demonstrated by the example with Pseudomonas aeruginosa]. |
| PubMed:Plant phenols as in vitro inhibitors of glutathione S-transferase(s). |
| PubMed:Functional differences between peroxidase compound I and the cytochrome P-450 reactive oxygen intermediate. |
| PubMed:A quantitative enzyme-linked immunoassay for serum immune complexes. |
| PubMed:Mutagenic and colicine-inducing activity of two antioxidants: pyrogallol and purpurogallin. |
| PubMed:The oxidation of some pyrogallol and purpurogallin derivatives. |
| PubMed:Oxidation of pyrogallol to purpurogallin by crystallin catalase. |
| PubMed:Purpurogallin. |
| PubMed:The oxidation products of phenols; the structure of purpurogallin. |
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3D/inchi