EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

phenyl t-butylnitrone
2-propanamine, 2-methyl-N-(phenylmethylene)-, N-oxide

Supplier Sponsors

CAS Number: 3376-24-7Picture of molecule3D/inchi
Other(deleted CASRN):115995-20-5
ECHA EINECS - REACH Pre-Reg:222-168-6
FDA UNII: 3I91332OPG
Nikkaji Web:J4.356G
Beilstein Number:2044028
MDL:MFCD00008799
XlogP3-AA:1.30 (est)
Molecular Weight:177.24675000
Formula:C11 H15 N O
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:antioxidants
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Soluble in:
 water, 4766 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: antioxidants
 
Suppliers:
BOC Sciences
For experimental / research use only.
N-tert-Butyl--phenylnitrone 95%
EMD Millipore
For experimental / research use only.
N-tert-Butyl-a-phenylnitrone
Santa Cruz Biotechnology
For experimental / research use only.
N-tert-Butyl-a-phenylnitrone 98%
Sigma-Aldrich
For experimental / research use only.
N-tert-Butyl-a-phenylnitrone for ESR-spectroscopy
TCI AMERICA
For experimental / research use only.
N-tert-Butyl-a-phenylnitrone >98.0%(HPLC)(T)
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
antioxidants
Recommendation for phenyl t-butylnitrone usage levels up to:
 not for fragrance use.
 
Recommendation for phenyl t-butylnitrone flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):3376-24-7
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :4390
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
N-tert-butyl-1-phenylmethanimine oxide
Chemidplus:0003376247
RTECS:TX1760000 for cas# 3376-24-7
 
References:
 N-tert-butyl-1-phenylmethanimine oxide
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):4390
Pubchem (sid):135022536
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2942.00.3500
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
N-tert-butyl-1-phenylmethanimine oxide
N-tert-butyl-a-phenylnitrone
N-tert-butyl-alpha-phenyl nitrone
2-methyl-N-(phenylmethylene)-S-propanamine N-oxide
2-propanamine, 2-methyl-N-(phenylmethylene)-, N-oxide
 

Articles:

PubMed:Natural Products Screening for the Identification of Selective Monoamine Oxidase-B Inhibitors.
PubMed:Downregulation of STAT3/NF-κB potentiates gemcitabine activity in pancreatic cancer cells.
PubMed:Berberine Antifungal Activity in Fluconazole-Resistant Pathogenic Yeasts: Action Mechanism Evaluated by Flow Cytometry and Biofilm Growth Inhibition in Candida spp.
PubMed:Extracting the Benefit of Nexrutine(®) for Cancer Prevention.
PubMed:Tolerance of Phellodendron amurense bark extract (Nexrutine®) in patients with human prostate cancer.
PubMed:Palmatine inhibits growth and invasion in prostate cancer cell: Potential role for rpS6/NFκB/FLIP.
PubMed:STAT3 down regulates LC3 to inhibit autophagy and pancreatic cancer cell growth.
PubMed:The anti-inflammatory potential of Cortex Phellodendron in vivo and in vitro: down-regulation of NO and iNOS through suppression of NF-κB and MAPK activation.
PubMed:Protective effects of Zhibai Dihuang Wan on renal tubular cells affected with gentamicin-induced apoptosis.
PubMed:Effect of Magnolia officinalis and Phellodendron amurense (Relora®) on cortisol and psychological mood state in moderately stressed subjects.
PubMed:Comparison the neuropreotective effect of Cortex Phellodendri chinensis and Cortex Phellodendri amurensis against beta-amyloid-induced neurotoxicity in PC12 cells.
PubMed:Discrimination of Phellodendron amurense and P. chinense based on DNA analysis and the simultaneous analysis of alkaloids.
PubMed:Bioguided isolation of (9Z)-octadec-9-enoic acid from Phellodendron amurense Rupr. and identification of fatty acids as PTP1B inhibitors.
PubMed:Comparison on the anti-inflammatory effect of Cortex Phellodendri Chinensis and Cortex Phellodendri Amurensis in 12-O-tetradecanoyl-phorbol-13-acetate-induced ear edema in mice.
PubMed:Effect of Phellodendron amurense in protecting human osteoarthritic cartilage and chondrocytes.
PubMed:Phellodendron amurense bark extract prevents progression of prostate tumors in transgenic adenocarcinoma of mouse prostate: potential for prostate cancer management.
PubMed:Natural products: potential for developing Phellodendron amurense bark extract for prostate cancer management.
PubMed:Extracts of bark from the traditional Chinese herb Phellodendron amurense inhibit contractility of the isolated rat prostate gland.
PubMed:Quality assessment of Cortex Phellodendri by high-performance liquid chromatography coupled with electrospray ionization mass spectrometry.
PubMed:Phellodendron and Citrus extracts benefit joint health in osteoarthritis patients: a pilot, double-blind, placebo-controlled study.
PubMed:In vitro antioxidant, antimicrobial and anti-herpes simplex virus type 1 activity of Phellodendron amurense Rupr. from China.
PubMed:Butanol fraction containing berberine or related compound from nexrutine inhibits NFkappaB signaling and induces apoptosis in prostate cancer cells.
PubMed:Phellodendron and Citrus extracts benefit cardiovascular health in osteoarthritis patients: a double-blind, placebo-controlled pilot study.
PubMed:Regulation of Cox-2 by cyclic AMP response element binding protein in prostate cancer: potential role for nexrutine.
PubMed:Akt/cAMP-responsive element binding protein/cyclin D1 network: a novel target for prostate cancer inhibition in transgenic adenocarcinoma of mouse prostate model mediated by Nexrutine, a Phellodendron amurense bark extract.
PubMed:Isolation of limonoids and alkaloids from Phellodendron amurense and their multidrug resistance (MDR) reversal activity.
PubMed:A rapid and simple determination of protoberberine alkaloids in cortex phellodendri by 1H NMR and its application for quality control of commercial traditional Chinese medicine prescriptions.
PubMed:Identification of dyes on ancient Chinese paper samples using the subtracted shifted Raman spectroscopy method.
PubMed:Principle of the bark of Phellodendron amurense to suppress the cellular immune response: effect of phellodendrine on cellular and humoral immune responses.
PubMed:Principle of the bark of Phellodendron amurense to suppress the cellular immune response.
 
Notes:
None found
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