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N-phenyl-p-phenylenediamine
p-phenylenediamine, N-phenyl-

Supplier Sponsors

CAS Number: 101-54-2Picture of molecule3D/inchi
Other(deleted CASRN):12227-74-6
ECHA EINECS - REACH Pre-Reg:202-951-9
FDA UNII: 007X4XXS71
Nikkaji Web:J4.017G
Beilstein Number:908935
MDL:MFCD00007850
XlogP3:2.50 (est)
Molecular Weight:184.24164000
Formula:C12 H12 N2
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:hair dyeing agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
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Google Patents:Search
US Patents:Search
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Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Appearance:purple-black solid or flake (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 66.00 °C. @ 760.00 mm Hg
Boiling Point: 354.00 °C. @ 760.00 mm Hg
Flash Point: 388.00 °F. TCC ( 197.80 °C. ) (est)
logP (o/w): 1.290 (est)
Soluble in:
 water, 1453 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: hair dyeing agents
 
Suppliers:
EMD Millipore
For experimental / research use only.
4-Aminodiphenylamine
Santa Cruz Biotechnology
For experimental / research use only.
N-Phenyl-p-phenylenediamine 98%
Sigma-Aldrich: Aldrich
For experimental / research use only.
N-Phenyl-p-phenylenediamine 98%
TCI AMERICA
For experimental / research use only.
Azoic Diazo Component 22 >98.0%(HPLC)(T)
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-cat LDLo 100 mg/kg
BLOOD: METHEMOGLOBINEMIA-CARBOXYHEMOGLOBIN LUNGS, THORAX, OR RESPIRATION: CYANOSIS
Journal of the American College of Toxicology. Vol. 13, Pg. 374, 1994.

oral-mouse LD50 244 mg/kg
BLOOD: HEMORRHAGE
Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 8, Pg. 126, 1966.

oral-rabbit LD50 > 5000 mg/kg
Journal of the American College of Toxicology. Vol. 13, Pg. 374, 1994.

oral-rat LD50 464 mg/kg
Progress Report for Contract No. NIH-NCI-E-C-72-3252, Submitted to the National Cancer Institute by Litton Bionetics, Inc. Vol. NCI-E-C-72-3252, Pg. 1973

Dermal Toxicity:
skin-rabbit LD50 > 5000 mg/kg
SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE BEHAVIORAL: FOOD INTAKE (ANIMAL) SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION
Acute Toxicity Data. Journal of the American College of Toxicology, Part B. Vol. 1, Pg. 63, 1990.

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
hair dyeing agents
Recommendation for N-phenyl-p-phenylenediamine usage levels up to:
 not for fragrance use.
 
Recommendation for N-phenyl-p-phenylenediamine flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
NIOSH International Chemical Safety Cards:search
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA GENetic TOXicology:Search
EPA Substance Registry Services (TSCA):101-54-2
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :7564
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
4-N-phenylbenzene-1,4-diamine
Chemidplus:0000101542
EPA/NOAA CAMEO:hazardous materials
RTECS:101-54-2
 
References:
 4-N-phenylbenzene-1,4-diamine
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:101-54-2
Pubchem (cid):7564
Pubchem (sid):134970828
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2921.59.8090
ChemSpider:View
Wikipedia:View
Formulations/Preparations:
hair dyes are prepared by combining 2,6-diaminopyridine or its salt, p-aminodiphenylamine or its salt, and 2,5-diaminopyridine or its salt at the mole ratio of 1:2:3.
 
Potential Blenders and core components note
None Found
 
Potential Uses:
 hair dyeing agents
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 acna black DF base
p-aminodifenylamin
p-aminodiphenylamine
N-(4-aminophenyl) aniline (c.i. 76085)
N-(4-aminophenyl)aniline
(4-aminophenyl)phenylamine
 azoic diazo component 22
 azoic diazo no. 22
 azosalt R
1,4-benzenediamine, N-phenyl-
1,4-benzenediamine, N1-phenyl-
 black base P
 c.i. 76085
 C.I. azoic diazo component 22
 C.I. developer 15
 C.I. oxidation base 2
 ci 76085
 CI azoic diazo component 22
 CI developer 15
 CI oxidation base 2
 developer 15
 diphenyl black base P
 diphenylamine, 4-amino-
 diphenylamine, p-amino-
 fast blue R salt
N-fenyl-p-fenylendiamin
 luxan black R
 naphthoelan navy blue
 oxidation base 2
 oxy acid black base
 peltol BR
N-phenyl-1,4-benzenediamine
N-phenyl-1,4-phenylene diamine
N-phenyl-1,4-phenylenediamine
N-phenyl-1,4-phenylenediamine sulfate
N-phenyl-p-aminoaniline
4-(phenylamino)aniline
p-(phenylamino)aniline
1-N-phenylbenzene-1,4-diamine
N-phenylbenzene-1,4-diamine
p-phenylenediamine, N-phenyl-
 rodol gray B base
p-semidine
 variamine blue RT
 variamine blue RT salt
 variamine blue salt RT
 
 
Notes:
None found
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