acetyl glutamic acid
N-acetyl glutamate

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CAS Number: 1188-37-0 3D/inchi Other(deleted CASRN): 7728-87-2 ECHA EINECS - REACH Pre-Reg: 214-708-4 FDA UNII: MA61H539YZ Nikkaji Web: J37.497K Beilstein Number: 1727473 MDL: MFCD00002802 XlogP3: -1.80 (est) Molecular Weight: 189.16767000 Formula: C7 H11 N O5 BioActivity Summary: listing NMR Predictor: Predict (works with chrome, Edge or firefox) EFSA/JECFA Comments: mp: 199-201°; Optical rotation: -25.6° (22 °C in water) Category:flavor enhancers, umami taste enhancer   US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information: Google Scholar: Search Google Books: Search Google Scholar: with word "volatile" Search Google Scholar: with word "flavor" Search Google Scholar: with word "odor" Search Google Patents: Search US Patents: Search EU Patents: Search Pubchem Patents: Search PubMed: Search NCBI: Search JECFA Food Flavoring: 2269 N-acetyl glutamate FEMA Number: 4752 N-acetyl glutamate FDA: No longer provide for the use of these seven synthetic flavoring substances   Physical Properties: Appearance: white powder (est) Assay: 95.00 to 100.00 Food Chemicals Codex Listed: No Melting Point: 199.00 to 201.00 °C. @ 760.00 mm Hg Boiling Point: 495.00 to 496.00 °C. @ 760.00 mm Hg Flash Point: 488.00 °F. TCC ( 253.33 °C. ) logP (o/w): -2.131 (est) Soluble in:   water, 8.524e+005 mg/L @ 25 °C (est)   Organoleptic Properties: Odor and/or flavor descriptions from others (if found).   Cosmetic Information: CosIng: cosmetic data Cosmetic Uses: skin conditioning   Suppliers: BOC Sciences For experimental / research use only. N-Acetyl-L-Glutamic acid 95% Carbosynth For experimental / research use only. N-Acetyl-L-glutamic acid Glentham Life Sciences N-Acetyl-L-glutamic acid sds Penta International N-ACETYL-L-GLUTAMIC ACID Santa Cruz Biotechnology For experimental / research use only. N-Acetyl-L-glutamic acid Sigma-Aldrich: Aldrich For experimental / research use only. N-Acetyl-L-glutamic acid, ReagentPlus®, 99% sds TCI AMERICA For experimental / research use only. N-Acetyl-L-glutamic Acid >98.0%(HPLC)(T) sds United International N-Acetyl-L-glutamic acid United International N-Acetyl-L-Glutamine Nat.   Safety Information: Preferred SDS: View   Hazards identification   Classification of the substance or mixture GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) None found. GHS Label elements, including precautionary statements   Pictogram   Hazard statement(s) None found. Precautionary statement(s) None found. Oral/Parenteral Toxicity: intraperitoneal-mouse LD50 711 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA Toksikologicheskii Vestnik. Vol. (3), Pg. 36, 1995. oral-mouse LD50 6838 mg/kg BRAIN AND COVERINGS: "CHANGES IN CIRCULATION (HEMORRHAGE, THROMBOSIS, ETC.)" LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BLOOD: HEMORRHAGE Toksikologicheskii Vestnik. Vol. (3), Pg. 36, 1995. oral-rat LD50 > 7000 mg/kg LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BRAIN AND COVERINGS: "CHANGES IN CIRCULATION (HEMORRHAGE, THROMBOSIS, ETC.)" BLOOD: HEMORRHAGE Toksikologicheskii Vestnik. Vol. (3), Pg. 36, 1995. Dermal Toxicity: Not determined Inhalation Toxicity: Not determined   Safety in Use Information: Category: flavor enhancers, umami taste enhancer Recommendation for acetyl glutamic acid usage levels up to:   not for fragrance use.   Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library publication number: 26 Click here to view publication 26   average usual ppm average maximum ppm baked goods: - - beverages(nonalcoholic): 50.00000 150.00000 beverages(alcoholic): - - breakfast cereal: - - cheese: 50.00000 150.00000 chewing gum: - - condiments / relishes: 20.00000 100.00000 confectionery froastings: - - egg products: - - fats / oils: 25.00000 100.00000 fish products: 50.00000 150.00000 frozen dairy: - - fruit ices: - - gelatins / puddings: - - granulated sugar: - - gravies: 50.00000 150.00000 hard candy: - - imitation dairy: 50.00000 150.00000 instant coffee / tea: 50.00000 150.00000 jams / jellies: - - meat products: 50.00000 150.00000 milk products: 50.00000 200.00000 nut products: - - other grains: - - poultry: 50.00000 150.00000 processed fruits: - - processed vegetables: 25.00000 100.00000 reconstituted vegetables: 25.00000 100.00000 seasonings / flavors: 50.00000 500.00000 snack foods: 50.00000 200.00000 soft candy: - - soups: 50.00000 150.00000 sugar substitutes: - - sweet sauces: 50.00000 150.00000   Safety References: EPI System: View AIDS Citations:Search Cancer Citations:Search Toxicology Citations:Search EPA Substance Registry Services (TSCA):1188-37-0 EPA ACToR:Toxicology Data EPA Substance Registry Services (SRS):Registry Laboratory Chemical Safety Summary :70914 National Institute of Allergy and Infectious Diseases:Data WGK Germany:2 (2S)-2-acetamidopentanedioic acid Chemidplus:0001188370 RTECS:LZ9725000 for cas# 1188-37-0   References:   (2S)-2-acetamidopentanedioic acid NIST Chemistry WebBook: Search Inchi Pubchem (cid): 70914 Pubchem (sid): 135028765   Other Information: (IUPAC): Atomic Weights of the Elements 2011 (pdf) Videos: The Periodic Table of Videos tgsc: Atomic Weights use for this web site (IUPAC): Periodic Table of the Elements CHEBI: View CHEMBL: View Golm Metabolome Database: Search Metabolomics Database: Search KEGG (GenomeNet): C00624 HMDB (The Human Metabolome Database): HMDB01138 FooDB: FDB022447 YMDB (Yeast Metabolome Database): YMDB00066 Export Tariff Code: 2924.19.1150 ChemSpider: View Wikipedia: View   Potential Blenders and core components note None Found   Potential Uses:   additives   skin conditioning   Occurrence (nature, food, other):note   not found in nature   Synonyms: (2S)-2- acetamidopentanedioic acid N- acetyl glutamate N- acetyl-L-glutamic acid N- acetyl-laevo-glutamic acid L- acetylglutamic acid L- glutamic acid, N-acetyl- laevo- glutamic acid, N-acetyl-   Articles:   None found yet. 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Notes: N-Acetylglutamic acid (abbreviated NAcGlu) is biosynthesized from glutamic acid and acetyl-CoA by the enzyme NAGS. The reverse reaction, hydrolysis of the acetyl group, is catalyzed by a specific hydrolase. [HMDB]