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lignin sodium sulfonate
lignosulfonic acid, sodium salt

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CAS Number: 8061-51-6
FDA UNII: XY2KOA860T
MDL:MFCD00135572
Formula:unspecified
Category:food-contact surface of paper and paperboard
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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FDA Mainterm (SATF):8061-51-6 ; LIGNIN SODIUM SULFONATE
FDA Regulation:
FDA PART 173 -- SECONDARY DIRECT FOOD ADDITIVES PERMITTED IN FOOD FOR HUMAN CONSUMPTION
Subpart D--Specific Usage Additives
Sec. 173.310 Boiler water additives.


FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS
Subpart B--Substances for Use Only as Components of Adhesives
Sec. 175.105 Adhesives.


FDA PART 176 -- INDIRECT FOOD ADDITIVES: PAPER AND PAPERBOARD COMPONENTS
Subpart B--Substances for Use Only as Components of Paper and Paperboard
Sec. 176.170 Components of paper and paperboard in contact with aqueous and fatty foods.


FDA PART 176 -- INDIRECT FOOD ADDITIVES: PAPER AND PAPERBOARD COMPONENTS
Subpart B--Substances for Use Only as Components of Paper and Paperboard
Sec. 176.180 Components of paper and paperboard in contact with dry food.


FDA PART 176 -- INDIRECT FOOD ADDITIVES: PAPER AND PAPERBOARD COMPONENTS
Subpart B--Substances for Use Only as Components of Paper and Paperboard
Sec. 176.210 Defoaming agents used in the manufacture of paper and paperboard.


FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS
Subpart B--Substances for Use as Basic Components of Single and Repeated Use Food Contact
Sec. 177.1210 Closures with sealing gaskets for food containers.
 
Physical Properties:
Appearance:pale tan powder (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Soluble in:
 water, 5.224e+005 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: surfactants
 
Suppliers:
BOC Sciences
For experimental / research use only.
Lignosulfonic acid sodium salt
Odor: characteristic
Use: A lignan-derived macromolecule with antiviral activity, efffective against HIV and HSV in vitro; an entry inhibitor, most effective if used upon pre-treatment
Santa Cruz Biotechnology
For experimental / research use only.
Sodium Ligninsulfonate
Sigma-Aldrich: Aldrich
For experimental / research use only.
Lignosulfonic acid sodium salt, average Mw ∼52,000, average Mn ∼7,000
sds
TCI AMERICA
For experimental / research use only.
Sodium Ligninsulfonate
sds
Chemical Sources Association
Need This Item for Flavor/Food?: You can contact the Chemical Sources Association
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-rat LD50 260 mg/kg
BEHAVIORAL: COMA BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: MUSCLE WEAKNESS
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 53(10), Pg. 92, 1988.

oral-mouse LD50 6030 mg/kg
BEHAVIORAL: COMA BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 53(10), Pg. 92, 1988.

intravenous-mouse LDLo 500 mg/kg
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 45, Pg. 685, 1956.

oral-rat LD > 10000 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: EXCITEMENT
Toksikologicheskii Vestnik. Vol. (1), Pg. 37, 1998.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
inhalation-rat LC > 480 mg/m3/4H
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: EXCITEMENT
Toksikologicheskii Vestnik. Vol. (1), Pg. 37, 1998.
 
Safety in Use Information:
Category:
food-contact surface of paper and paperboard
Recommendation for lignin sodium sulfonate usage levels up to:
 not for fragrance use.
 
Recommendation for lignin sodium sulfonate flavor usage levels up to:
 not for flavor use.
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Scientific Opinion on the safety and efficacy of lignosulphonate as a feed additive for all animal species
View page or View pdf

EPI System: View
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):8061-51-6
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:1
Chemidplus:0008061516
EPA/NOAA CAMEO:hazardous materials
RTECS:OI6174000 for cas# 8061-51-6
 
References:
Canada Domestic Sub. List:8061-51-6
Pubchem (sid):135264405
 
Other Information:
FDA Substances Added to Food (formerly EAFUS):View
FDA Indirect Additives used in Food Contact Substances:View
HMDB (The Human Metabolome Database):Search
Export Tariff Code:3912.90.0090
FDA Listing of Food Additive Status:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
 surfactants
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 banirex N
sulfonated lignin sodium salt
 lignin sodium sulfonate
 lignosite 458
 lignosol XD
 lignosulfonic acid sodium salt
 lignosulfonic acid, sodium salt
 maracell C
 marasperse N
 orzan CG
 polignate sodium
 polyfon F
 reax 80C
 reveal NM
 sodium lignin sulfonate
 sodium ligninsulfonate
 sodium lignosulfite
 sodium lignosulfonate
 sodium polignate
 vanicell
 vanirex N
 vanisperse
 wanin S
 

Articles:

PubMed:A novel and efficient polymerization of lignosulfonates by horseradish peroxidase/H(2)O(2) incubation.
PubMed:Reducing non-productive adsorption of cellulase and enhancing enzymatic hydrolysis of lignocelluloses by noncovalent modification of lignin with lignosulfonate.
PubMed:Encapsulation of the herbicide picloram by using polyelectrolyte biopolymers as layer-by-layer materials.
PubMed:Preparation of starch-sodium lignosulfonate graft copolymers via laccase catalysis and characterization of antioxidant activity.
PubMed:Surfactant-mediated electrodeposition of bismuth telluride films and its effect on microstructural properties.
PubMed:Effect of molecular weight on the adsorption characteristics of lignosulfonates.
PubMed:Effect of supramolecular structures on thermoplastic zein-lignin bionanocomposites.
PubMed:Adsorption characteristics of lignosulfonates in salt-free and salt-added aqueous solutions.
PubMed:Aggregation behavior of sodium lignosulfonate in water solution.
PubMed:Lignin-based activated carbons for adsorption of sodium dodecylbenzene sulfonate: Equilibrium and kinetic studies.
PubMed:Screening of different adjuvants for wastewater/wastewater sludge-based Bacillus thuringiensis formulations.
PubMed:Purification and characterization of laccase produced by a white rot fungus Pleurotus sajor-caju under submerged culture condition and its potential in decolorization of azo dyes.
PubMed:Laccase from the medicinal mushroom Agaricus blazei: production, purification and characterization.
PubMed:Whole-mount silver staining of Arabidopsis and maize: a new method for staining secondary wall thickenings in tracheary elements.
PubMed:Ozonolysis mechanism of lignin model compounds and microbial treatment of organic acids produced.
PubMed:Acidified litter benefits the intestinal flora balance of broiler chickens.
PubMed:Novel laccase redox mediators: spectral, electrochemical, and kinetic properties.
PubMed:A novel extracellular multicopper oxidase from Phanerochaete chrysosporium with ferroxidase activity.
PubMed:[Determination of relative molecular mass distribution of electro-oxidative degradation products of lignosulfonate by gel permeation chromatography].
PubMed:The study of modified calcium hydroxides with surfactants for acid gas removal during incineration.
PubMed:Purification and characterization of a new member of the laccase family from the white-rot basidiomycete Coriolus hirsutus.
PubMed:Interaction between sodium ascorbate and polyphenols.
PubMed:Enhancement of radical intensity and cytotoxic activity of ascorbate by PSK and lignins.
PubMed:Ascorbyl radical scavenging activity of polyphenols.
PubMed:[Work conditions and health status of workers in present-day production of disperse azo dyes].
PubMed:Teratogenic effects of the fungicide maneb on chick embryos.
PubMed:Prevention of formation of acid drainage from high-sulfur coal refuse by inhibition of iron- and sulfur-oxidizing microorganisms. I. Preliminary experiments in controlled shaken flasks.
PubMed:Abnormal limb regeneration in adult newts exposed to the fungicide Maneb 80. A histological study.
PubMed:Sulfur requirement of lactating dairy cows. II. Utilization of sulfates, molasses, and lignin-sulfonate.
PubMed:The biological degradation of lignin. IV. The inability of Polyporus versicolor to metabolize sodium lignosulfonate.
 
Notes:
None found
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