EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes

calcium threonate
L-threonic acid calcium salt

Supplier Sponsors

CAS Number: 70753-61-6Picture of molecule3D/inchi
FDA UNII: HBB4YPO93U
Nikkaji Web:J624.916G
Beilstein Number:5166008
MDL:MFCD00077882
Molecular Weight:310.26958000
Formula:C8 H14 Ca O10
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:nutrient supplements
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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PubMed:Search
NCBI:Search
 FDA/DG SANTE Petitions, Reviews, Notices:
GRN 451 Calcium ascorbate with added threonate View - notice PDF
 
Physical Properties:
Appearance:white granular powder (est)
Assay: 98.50 to 100.00
Food Chemicals Codex Listed: No
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
Soluble in:
 water, slightly
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
Calcium L-threonate
Carbosynth
For experimental / research use only.
Calcium L-threonate
Glentham Life Sciences
Calcium L-threonate
Santa Cruz Biotechnology
For experimental / research use only.
L-Threonic acid hemicalcium salt
Sigma-Aldrich: Aldrich
For experimental / research use only.
L-Threonic acid hemicalcium salt >97%
sds
TCI AMERICA
For experimental / research use only.
Calcium L-Threonate >98.0%(T)
sds
Chemical Sources Association
Need This Item for Flavor/Food?: You can contact the Chemical Sources Association
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
nutrient supplements
Recommendation for calcium threonate usage levels up to:
 not for fragrance use.
 
Recommendation for calcium threonate flavor usage levels up to:
 not for flavor use.
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Opinion on Calcium L-threonate for use as a source of calcium in food supplements - Scientific Panel on Food Additives and Nutrient Sources added to food (ANS)
View page or View pdf

Daily Med:search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :13388558
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
calcium (2R,3S)-2,3,4-trihydroxybutanoate
Chemidplus:0070753616
 
References:
 calcium (2R,3S)-2,3,4-trihydroxybutanoate
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):13388558
Pubchem (sid):135289869
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2918.19.9000
FDA Listing of Food Additive Status:View
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 calcium (2R,3S)-2,3,4-trihydroxybutanoate
 calcium L-threonate
 calcium laevo-threonate
L-threonic acid calcium salt
laevo-threonic acid calcium salt
 threonine calcium salt
 

Articles:

PubMed:Calcium bioavailability of calcium L-threonate in healthy Chinese subjects measured with stable isotopes (⁴⁴Ca and ⁴²Ca).
PubMed:Pharmacokinetics and safety of calcium L-threonate in healthy volunteers after single and multiple oral administrations.
PubMed:Vitamin C-lipid metabolites: uptake and retention and effect on plasma C-reactive protein and oxidized LDL levels in healthy volunteers.
PubMed:Absorption rates and free radical scavenging values of vitamin C-lipid metabolites in human lymphoblastic cells.
PubMed:[Effects of L-threonate on bone resorption by osteoclasts in vitro].
PubMed:[FTIR studies of L-threonic acid and its metal compounds].
PubMed:Enhanced production of mineralized nodules and collagenous proteins in vitro by calcium ascorbate supplemented with vitamin C metabolites.
PubMed:Determination of L-threonate in calcium L-threonate preparations by capillary electrophoresis with indirect UV detection.
PubMed:Effect of aldonic acids on the uptake of ascorbic acid by 3T3 mouse fibroblasts and human T lymphoma cells.
PubMed:Stimulatory action of calcium L-threonate on ascorbic acid uptake by a human T-lymphoma cell line.
PubMed:Comparison of the anti-scorbutic activity of L-ascorbic acid and Ester C in the non-ascorbate synthesizing Osteogenic Disorder Shionogi (ODS) rat.
 
Notes:
None found
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