EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

dextro,laevo-proline
DL-2-pyrrolidinecarboxylic acid

Supplier Sponsors

Name:pyrrolidine-2-carboxylic acid
CAS Number: 609-36-9Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:210-189-3
FDA UNII: DCS9E77JPQ
Nikkaji Web:J1.287D
Beilstein Number:0080812
MDL:MFCD00005250
XlogP3:-2.50 (est)
Molecular Weight:115.13213000
Formula:C5 H9 N O2
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:information only not used for fragrances or flavors
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Appearance:colorless crystals (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 205.00 °C. @ 760.00 mm Hg
Soluble in:
 water, 1.313e+005 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Alfa Biotechnology
For experimental / research use only.
DL-Proline 98%
BOC Sciences
For experimental / research use only.
DL-Proline 98%
Glentham Life Sciences
DL-Proline
sds
Santa Cruz Biotechnology
For experimental / research use only.
DL-Proline
Sigma-Aldrich: Aldrich
For experimental / research use only.
DL-Proline ReagentPlus®, 99%
sds
TCI AMERICA
For experimental / research use only.
DL-Proline >99.0%(T)
sds
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
information only not used for fragrances or flavors
Recommendation for dextro,laevo-proline usage levels up to:
 not for fragrance use.
 
Recommendation for dextro,laevo-proline flavor usage levels up to:
 not for flavor use.
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Safety of proline-specific oligopeptidase as a novel food pursuant to Regulation (EC) No 258/97
View page or View pdf

EPI System: View
Daily Med:search
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):609-36-9
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :614
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
pyrrolidine-2-carboxylic acid
Chemidplus:0000609369
 
References:
 pyrrolidine-2-carboxylic acid
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):614
Pubchem (sid):134978485
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
Golm Metabolome Database:Search
KEGG (GenomeNet):C16435
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2933.99.9700
ChemSpider:View
Wikipedia:View
Formulations/Preparations:
usp and fcc grades
 
Potential Blenders and core components note
None Found
 
Potential Uses:
 antistatic agents
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
DL-proline
 proline DL-form
 proline, DL-
2-pyrrolidine carboxylic acid
 pyrrolidine-2-carboxylic acid
(+/-)-pyrrolidine-2-carboxylic acid
(R,S)-pyrrolidine-2-carboxylic acid
DL-pyrrolidine-2-carboxylic acid
DL-2-pyrrolidinecarboxylic acid
 

Articles:

PubMed:Thermodynamic and conformational study of proline stereoisomers.
PubMed:The γ-aminobutyrate permease GabP serves as the third proline transporter of Bacillus subtilis.
PubMed:Concise NMR approach for molecular dynamics characterizations in organic solids.
PubMed:A domino Knoevenagel hetero-Diels-Alder reaction for the synthesis of polycyclic chromene derivatives and evaluation of their cytotoxicity.
PubMed:L-Proline nutrition and catabolism in Staphylococcus saprophyticus.
PubMed:Structural characterization and reactivity of gamma-octamolybdate functionalized by proline.
PubMed:[Ligand exchange chromatographic separation of DL-amino acids based on monodisperse resin-bonded chiral stationary phase].
PubMed:DL-Proline.
PubMed:Oxidation of 3,4-dehydro-D-proline and other D-amino acid analogues by D-alanine dehydrogenase from Escherichia coli.
PubMed:Probing the reaction pathways of DL-proline on TiO2 (001) single crystal surfaces.
PubMed:Transport of pharmacologically active proline derivatives by the human proton-coupled amino acid transporter hPAT1.
PubMed:Identification of regions of the tomato gamma-glutamyl kinase that are involved in allosteric regulation by proline.
PubMed:Dichlorobis(DL-proline-kappaO)zinc(II).
PubMed:Three modifications in the D and T arms of tRNA influence translation in Escherichia coli and expression of virulence genes in Shigella flexneri.
PubMed:Chiral polyoxotungstates. 1. Stereoselective interaction of amino acids with enantiomers of [Ce(III)(alpha1-P2W17O61)(H2O)x]7-. The structure of DL-[Ce2(H2O)8(P2W17O61)2]14-.
PubMed:Accurate experimental electronic properties of dl-proline monohydrate obtained within 1 Day
PubMed:The influence of proline analogs on bleomycin-induced lung injury in rats.
PubMed:Purification and Characterization of an l-Amino Amidase from Mycobacterium neoaurum ATCC 25795.
PubMed:Effect of novel compound, 1-methyl-1-piperidino methane sulfonate (MPMS), on the osmoprotectant activity of glycine betaine, choline and L-proline in Escherichia coli.
PubMed:Inhibitors of C1q biosynthesis suppress activation of murine macrophages for both antibody-independent and antibody-dependent tumor cytotoxicity.
PubMed:Effects of inhibitors of C1q biosynthesis on macrophage Fc receptor subclass-mediated antibody-dependent cellular cytotoxicity and phagocytosis.
PubMed:Energetics of proline racemase: transition-state fractionation factors for the two protons involved in the catalytic steps.
PubMed:Channel structures in synthetic polypeptides with alternating configurations. Conformational analysis of poly(DL-proline).
PubMed:Poly(DL-proline), a synthetic polypeptide behaving as an ion channel across bilayer membranes.
PubMed:Identification of a mutation that relieves gamma-glutamyl kinase from allosteric feedback inhibition by proline.
PubMed:L-Proline transport in Saccharomyces cerevisiae.
PubMed:Proline transport in Saccharomyces cerevisiae.
PubMed:Retrograde amnesia in chicks and mice induced by 3,4-dehydro-DL-proline, a proline analog.
PubMed:Construction of an L-arginine-producing mutant in Serratia marcescens. Use of the wide substrate specificity of acetylornithinase.
PubMed:Potential inhibitors of collagen biosynthesis, 4,4-Difluoro-L-proline and 4,4-dimethyl-DL-proline and their activation by prolyl-tRNA ligase.
PubMed:The use of hydroxy-DL-proline-2-(14)C in the investigation of hydroxyproline metabolism in normal subjects and in patients with renal insufficiency.
PubMed:Preparation of optically active proline. Optical resolution of N-acyl-DL-proline by preferential crystallization procedure.
PubMed:Differences in the incorporation of L- and DL-Amino acids into renal tubular cells. An autoradiographic study.
PubMed:13C magnetic resonance study of the ionization of N-acetyl-DL-proline in aqueous solution.
PubMed:Induction of prodigiosin biosynthesis after shift-down in temperature of nonproliferating cells of Serratia marcescens.
PubMed:Proline as an intermediate in the reductive deamination of ornithine to delta-aminovaleric acid.
PubMed:Effect of structural and stereochemical methylproline isomers on actinomycin biosynthesis.
PubMed:Purification, properties and comparative specificities of the enzyme prolyl-transfer ribonucleic acid synthetase from Phaseolus aureus and Polygonatum multiflorum.
PubMed:PROLINE OXIDASES IN HANSENULA SUBPELLICULOSA.
PubMed:SYNTHESIS OF 4-METHYLENE-DL-PROLINE: A NATURALLY OCCURRING RACEMIC AMINO-ACID.
PubMed:EFFECT OF 3,4-DEHYDRO-DL-PROLINE ON GROWTH AND PROTEIN SYNTHESIS.
PubMed:The synthesis of amino acids from 2,3-dihydrofuran DL-ornithine, DL-proline, and DL-alpha-amino-delta-hydroxyvaleric acid.
 
Notes:
None found
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