EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

dextro-mannose
D-mannopyranose

Supplier Sponsors

Name:(3S,4S,5S,6R)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol
CAS Number: 3458-28-4Picture of molecule3D/inchi
Other(deleted CASRN):147-74-0
ECHA EINECS - REACH Pre-Reg:222-392-4
FDA UNII: PHA4727WTP
Nikkaji Web:J182.296I
Beilstein Number:1423215
MDL:MFCD00064122
XlogP3-AA:-2.60 (est)
Molecular Weight:180.15684000
Formula:C6 H12 O6
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:humectants
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 132.00 °C. @ 760.00 mm Hg
Boiling Point: 410.80 °C. @ 760.00 mm Hg (est)
Flash Point: 396.00 °F. TCC ( 202.20 °C. ) (est)
logP (o/w): -2.490 (est)
Soluble in:
 water, 7.13E+05 mg/L @ 17C (exp)
 water, 1e+006 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: humectants
 
Suppliers:
Alfa Biotechnology
For experimental / research use only.
D-(+)-Mannose 98%
BOC Sciences
For experimental / research use only.
D(+)-Mannose
Charkit Chemical
MANNOSE, D-
ECSA Chemicals
D-MANNOSE
ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY
ExtraSynthese
For experimental / research use only.
D-(+)-Mannose
Fleurchem
d-mannose natural
Glentham Life Sciences
D-(+)-Mannose, 99%, from wood
Glentham Life Sciences
D-(+)-Mannose
H. Interdonati, Inc.
Mannose, D-
Featured Products
Indis NV
For experimental / research use only.
D-Mannose
Jiangyin Healthway
D-Mannose
New functional food ingredients
Penta International
D-MANNOSE
Pfanstiehl, Inc
Mannose, High Purity (Low Endotoxin)
Odor: characteristic
Use: Mannose is a C-2 epimer of glucose and a sugar monomer of the aldohexose series of carbohydrates. Mannose is important in human metabolism, particularly in the proper glycosylation of native proteins. It follows that extracellular mannose has been demonstrated to play a critical and ever-increasing role in the optimization of protein therapeutics bioproduction.
Santa Cruz Biotechnology
For experimental / research use only.
D-Mannose 99%
Sigma-Aldrich: Sigma
For experimental / research use only.
D-(+)-Mannose from wood, ≥99%
sds
United International
D-Mannose
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
humectants
Recommendation for dextro-mannose usage levels up to:
 not for fragrance use.
 
Recommendation for dextro-mannose flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):3458-28-4
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :18950
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
(3S,4S,5S,6R)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol
Chemidplus:0003458284
 
References:
 (3S,4S,5S,6R)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:3458-28-4
Pubchem (cid):18950
Pubchem (sid):135136220
Pherobase:View
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
Golm Metabolome Database:Search
Metabolomics Database:Search
KEGG (GenomeNet):C00159
HMDB (The Human Metabolome Database):HMDB00169
FooDB:FDB001202
YMDB (Yeast Metabolome Database):YMDB00894
Export Tariff Code:2940.00.0000
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 apple plant
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 basil seed
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 bean mung bean seed
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 cacao bean
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 caraway seed
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 carob bean
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 carrot root
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 carrot root
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 cashew sap
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 chicory root
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 coffee bean
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 corn plant
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 date palm seed
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 fenugreek plant
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 ginkgo biloba wood
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 guava leaf
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 guava leaf oil
Search Trop Picture
 marango sap
Search Trop Picture
 orange fruit
Search Trop Picture
 plum fruit
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 potato plant
Search Trop Picture
 puya raimondii
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 roselle calyx
Search Trop Picture
 wheat seed
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Synonyms:
 carubinose
(3S,4S,5S,6R)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol
D-mannopyranose
 mannopyranose, D-
(+)-mannose
D-mannose
D-(+)-mannose
 mannose, D-
 seminose
 

Articles:

PubMed:Mucilage chemical profile and antioxidant properties of giant swamp taro tubers.
PubMed:Facile enzymatic synthesis of sugar 1-phosphates as substrates for phosphorylases using anomeric kinases.
PubMed:Enzymatic Saccharification of Cassava Residues and Glucose Inhibitory Kinetics on β-Glucosidase from Hypocrea orientalis.
PubMed:Structural insights into the substrate specificity and transglycosylation activity of a fungal glycoside hydrolase family 5 β-mannosidase.
PubMed:Low temperature storage affects the ascorbic acid metabolism of cherry tomato fruits.
PubMed:Bacillus invictae sp. nov., isolated from a health product.
PubMed:Chemical composition of Pleurotus eryngii polysaccharides and their inhibitory effects on high-fructose diet-induced insulin resistance and oxidative stress in mice.
PubMed:Structural elucidation of the exopolysaccharide produced by the mangrove fungus Penicillium solitum.
PubMed:Transient expression analysis revealed the importance of VTC2 expression level in light/dark regulation of ascorbate biosynthesis in Arabidopsis.
PubMed:GC/MS-based metabolomics approach to identify biomarkers differentiating survivals from death in crucian carps infected by Edwardsiella tarda.
PubMed:Fraction and chemical analysis of antioxidant active polysaccharide isolated from flue-cured tobacco leaves.
PubMed:Purification and Partial Characterization of a Novel Anti-tumor Glycoprotein from Cultured Mycelia of Grifola frondosa.
PubMed:Synthesis of thymol glycosides under SCCO2 conditions using amyloglucosidase from Rhizopus mold.
PubMed:Structural characterization and biosorption of exopolysaccharides from Anoxybacillus sp. R4-33 isolated from radioactive radon hot spring.
PubMed:SGP-2, an acidic polysaccharide from Sarcandra glabra, inhibits proliferation and migration of human osteosarcoma cells.
PubMed:Isolation and structural characterization of a novel antioxidant mannoglucan from a marine bubble snail, Bullacta exarata (Philippi).
PubMed:Structural investigation of a novel heteropolysaccharide from the fruiting bodies of Boletus edulis.
PubMed:Effects of ovalbumin glycoconjugates on alleviation of orally induced egg allergy in mice via dendritic-cell maturation and T-cell activation.
PubMed:Characterization and bioactivity of polysaccharides obtained from pine cones of Pinus koraiensis by graded ethanol precipitation.
PubMed:Lectin Activity in Gut Extract of Culex pipiens.
PubMed:Evidence of metabolic switching and implications for food safety from the phenome(s) of Salmonella enterica serovar Typhimurium DT104 cultured at selected points across the pork production food chain.
PubMed:The effect of mannosylation of liposome-encapsulated indocyanine green on imaging of sentinel lymph node.
PubMed:In vitro growth of four individual human gut bacteria on oligosaccharides produced by chemoenzymatic synthesis.
PubMed:Ethanol production from high cellulose concentration by the basidiomycete fungus Flammulina velutipes.
PubMed:Defects in D-rhamnosyl residue biosynthetic genes affect lipopolysaccharide structure, motility, and cell-surface hydrophobicity in Pseudomonas syringae pathovar glycinea race 4.
PubMed:Metabolic profiling of Chinese tobacco leaf of different geographical origins by GC-MS.
PubMed:Metabolic engineering of Corynebacterium glutamicum to produce GDP-L-fucose from glucose and mannose.
PubMed:Effect of grinding intensity and feed physical form on in vitro adhesion of Salmonella Typhimurium and mannose residues in intestinal mucus receptors for salmonellae.
PubMed:Recent advances on physiological functions and biotechnological production of epilactose.
PubMed:The effectiveness of selected feed and water additives for reducing Salmonella spp. of public health importance in broiler chickens: a systematic review, meta-analysis, and meta-regression approach.
PubMed:A polysaccharide from Sargassum fusiforme protects against immunosuppression in cyclophosphamide-treated mice.
PubMed:In vitro adherence patterns of Shigella serogroups to bovine recto-anal junction squamous epithelial (RSE) cells are similar to those of Escherichia coli O157.
PubMed:A novel two-step synthesis of α-linked mannobioses based on an acid-assisted reverse hydrolysis reaction.
PubMed:Bovine recto-anal junction squamous epithelial (RSE) cell adhesion assay for studying Escherichia coli O157 adherence.
PubMed:The importance of inter-species cell-cell co-aggregation between Lactobacillus plantarum ML11-11 and Saccharomyces cerevisiae BY4741 in mixed-species biofilm formation.
PubMed:Enzymatic synthesis of cholecalciferol glycosides using β-glucosidase from sweet almond.
PubMed:Association of Lactobacillus acidophilus with mice Peyer's patches.
PubMed:Characterisation of a haemagglutinin from Hokkaido red bean (Phaseolus vulgaris cv. Hokkaido red bean).
PubMed:[Study on the structure and constituents of polysaccharide from ganoderma lucidum].
PubMed:Isolation of beta-mannanase from Cocos nucifera Linn haustorium and its application in the depolymerization of beta-(1,4)-linked D-mannans.
PubMed:Ascorbate metabolism and the developmental demand for tartaric and oxalic acids in ripening grape berries.
PubMed:Bovine Muc1 inhibits binding of enteric bacteria to Caco-2 cells.
PubMed:Physicochemical properties and antioxidant capacity of 3 polysaccharides from green tea, oolong tea, and black tea.
PubMed:Mannose-binding lectin from yam (Dioscorea batatas) tubers with insecticidal properties against Helicoverpa armigera (Lepidoptera: Noctuidae).
PubMed:Xylose reductase activity in Debaryomyces hansenii UFV-170 cultivated in semi-synthetic medium and cotton husk hemicellulose hydrolyzate.
PubMed:Efficient lipase-selective synthesis of dilauryl mannoses by simultaneous reaction-extraction system.
PubMed:Syntheses of retinol glycosides using beta-glucosidase in SCCO(2) media.
PubMed:Cryoprotective activity of mannoprotein from the cell membrane of Pichia anomala.
PubMed:Syntheses of dopa glycosides using glucosidases.
PubMed:An overview of mannan structure and mannan-degrading enzyme systems.
PubMed:Crystal structure of YihS in complex with D-mannose: structural annotation of Escherichia coli and Salmonella enterica yihS-encoded proteins to an aldose-ketose isomerase.
PubMed:GDP-perosamine synthase: structural analysis and production of a novel trideoxysugar.
PubMed:Structural characterization and serological specificities of lipopolysaccharides from Salmonella enterica serovar Gallinarum biovar Pullorum standard, intermediate and variant antigenic type strains.
PubMed:Lactobacillus ghanensis sp. nov., a motile lactic acid bacterium isolated from Ghanaian cocoa fermentations.
PubMed:Syntheses of N-vanillyl-nonanamide glycosides using amyloglucosidase from Rhizopus and beta-glucosidase from sweet almond.
PubMed:Effect of dietary beta1-4 mannobiose in the prevention of Salmonella enteritidis infection in broilers.
PubMed:The missing step of the L-galactose pathway of ascorbate biosynthesis in plants, an L-galactose guanyltransferase, increases leaf ascorbate content.
PubMed:Structural elucidation of a 3-O-methyl-D-galactose-containing neutral polysaccharide from the fruiting bodies of Phellinus igniarius.
PubMed:Generation of antibodies specific to D-mannitol, a unique haptenic allergen, using reductively aminated D-mannose-bovine serum albumin conjugate as the immunogen.
PubMed:Amyloglucosidase-catalyzed synthesis of eugenyl and curcuminyl glycosides.
PubMed:Factors involved in binding of Lactobacillus plantarum Lp6 to rat small intestinal mucus.
PubMed:Novel substrate specificity of D-arabinose isomerase from Klebsiella pneumoniae and its application to production of D-altrose from D-psicose.
PubMed:Reaction on D-glucal by an inverting phosphorylase to synthesize derivatives of 2-deoxy-beta-D-arabino-hexopyranosyl-(1-->4)-D-glucose (2II-deoxycellobiose).
PubMed:Equine spermatozoal motility and fertility associated with the incorporation of d-(+)-mannose into semen extender.
PubMed:Insecticidal activity of Arum maculatum tuber lectin and its binding to the glycosylated insect gut receptors.
PubMed:Histochemical analysis of glycoconjugate secretion in the alimentary canal of Anguilla anguilla L.
PubMed:Isomerisation of aldoses in pyridine in the presence of aluminium oxide.
PubMed:Regioselectivity in beta-galactosidase-catalyzed transglycosylation for the enzymatic assembly of D-galactosyl-D-mannose.
PubMed:Analysis of reducing carbohydrates by reductive tryptamine derivatization prior to micellar electrokinetic capillary chromatography.
PubMed:Synthesis of FimH receptor-active manno-oligosaccharides by reverse hydrolysis using alpha-mannosidases from Penicillium citrinum, Aspergillus phoenicis and almond.
PubMed:Characterization of a cellobiose phosphorylase from a hyperthermophilic eubacterium, Thermotoga maritima MSB8.
PubMed:Staphylococcus succinus subsp. casei subsp. nov., a dominant isolate from a surface ripened cheese.
PubMed:Weissella kimchii sp. nov., a novel lactic acid bacterium from kimchi.
PubMed:Sensitive and rapid immunoassays for Salmonella enteritidis.
PubMed:Effect of molecular structure and water content on the dielectric relaxation behaviour of amorphous low molecular weight carbohydrates above and below their glass transition.
PubMed:Isolation and characterization of a novel polysaccharide as a possible allergen occurring in wheat flour.
PubMed:Haloanaerobium fermentans sp. nov., a strictly anaerobic, fermentative halophile isolated from fermented puffer fish ovaries.
PubMed:Staphylococcus fleurettii sp. nov., isolated from goat's milk cheeses.
PubMed:Use of an enzyme-linked lectinsorbent assay to monitor the shift in polysaccharide composition in bacterial biofilms.
PubMed:Use of specific sugars to inhibit bacterial adherence to equine endometrium in vitro.
PubMed:Lactobacillus nagelii sp. nov., an organism isolated from a partially fermented wine.
PubMed:Transglycosylation reactions of Bacillus stearothermophilus maltogenic amylase with acarbose and various acceptors.
PubMed:In vitro attachment of Salmonella typhimurium to chicken cecal mucus: effect of cations and pretreatment with Lactobacillus spp. isolated from the intestinal tracts of chickens.
PubMed:Action of Trichoderma reesei mannanase on galactoglucomannan in pine kraft pulp.
PubMed:Genetic analysis of the acetan biosynthetic pathway in Acetobacter xylinum: nucleotide sequence analysis of the aceB, aceC, aceD and aceE genes.
PubMed:Synthesis of three hetero disaccharides, 4-O-beta-glucopyranosyl-6-deoxy-D-glucose, 4-O-beta-D-glucopyranosyl-D-mannosamine, and 4-O-beta-D-glucopyranosyl-D-mannose, and confirmation of their structures by C-13 NMR and MS.
PubMed:Certain functional properties of gums derived from some lesser known tropical legumes (Afzelia africana, Detarium microcarpum and Mucuna flagellipes).
PubMed:Antitumor activities and immunochemical properties of the cell-wall polysaccharides from Aureobasidium pullulans.
PubMed:The cuticular localization of integument peptides from particular routing categories.
PubMed:Identification of the Staphylococcus sciuri species group with EcoRI fragments containing rRNA sequences and description of Staphylococcus vitulus sp. nov.
PubMed:Effect of mannose on Salmonella typhimurium-mediated loss of mucosal epithelial integrity in cultured chick intestinal segments.
PubMed:2-O-methyl-D-mannose residues are immunodominant in extracellular polysaccharides of Mucor racemosus and related molds.
PubMed:[Effects of Coriolus versicolor polysaccharides on productivity and longevity in Drosophila melanogaster].
PubMed:The alpha-mannosyl-binding lectin from leaves of the orchid twayblade (Listera ovata). Application to separation of alpha-D-mannans from alpha-D-glucans.
PubMed:Evidence that the enzyme catalyzing the conversion of guanosine diphosphate D-mannose to a 4-keto sugar nucleotide intermediate requires nicotinamide adenine dinucleotide phosphate.
PubMed:Kinetic heterogeneity of Na-D-glucose cotransport in teleost gastrointestinal tract.
PubMed:Isolation, characterization, and antitumor activities of the cell wall polysaccharides from Elsinoe leucospila.
PubMed:Effects of D-mannose on incidence and levels of salmonellae in ceca and carcass samples of market age broilers.
PubMed:Effect of d-mannose on fimbriae of bacterial isolates from chicken carcasses.
PubMed:Prevention of Salmonella typhimurium colonization of broilers with D-mannose.
PubMed:Role of the glucopyranose ring in the elicitation of feeding.
PubMed:D-glucose suppression of eating after intra-third ventricle infusion in rat.
 
Notes:
a hexose or fermentable monosaccharide and isomer of glucose from manna, the ash fraxinus ornus and related plants. (from grant & hackh's chemical dictionary, 5th ed & random house unabridged dictionary, 2d ed) Occurs in trace amounts in apples and peaches. Obt. from the hydrolysates of D-mannans of the corms of Amorphophallus konjac (devil's tongue)
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