EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

glucosamine HCl
D-glucose, 2-amino-2-deoxy-, hydrochloride (1:1)

Supplier Sponsors

Name:(2R,3R,4S,5R)-2-amino-3,4,5,6-tetrahydroxyhexanal;hydrochloride
CAS Number: 66-84-2Picture of molecule3D/inchi
Other(deleted CASRN):151799-45-0
ECHA EINECS - REACH Pre-Reg:200-638-1
FDA UNII: 750W5330FY
Beilstein Number:4157370
MDL:MFCD00135831
Molecular Weight:215.63258000
Formula:C6 H14 Cl N O5
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:cosmetic agents, dietary supplements
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
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Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 FDA/DG SANTE Petitions, Reviews, Notices:
GRN 150 7 Glucosamine hydrochloride prepared from chitin obtained from Aspergillus niger View - notice PDF
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 532.50 °C. @ 760.00 mm Hg (est)
Flash Point: 528.00 °F. TCC ( 275.80 °C. ) (est)
logP (o/w): -2.375 (est)
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: antistatic agents
hair conditioning
 
Suppliers:
AIDP
Glucosamine HCl (Low Lead) 99% min.
AIDP
Glucosamine HCl 95% 93.5% min
AIDP
Glucosamine HCl 99%-101%
BOC Sciences
For experimental / research use only.
D-Glucosamine Hydrochloride
Charkit Chemical
GLUCOSAMINE HCL 40-80 MESH
Charkit Chemical
GLUCOSAMINE HCL DC
Charkit Chemical
GLUCOSAMINE HCL,D- 20 MESH 95%
EMD Millipore
For experimental / research use only.
D(+)Glucosamine, Hydrochloride
sds
Foodchem International
Glucosamine HCL
Glentham Life Sciences
D-Glucosamine hydrochloride, USP grade
Glentham Life Sciences
D-Glucosamine hydrochloride
Indis NV
For experimental / research use only.
Glucosamine Hcl
Jiangyin Healthway
D-Glucosamine Hydrochloride
New functional food ingredients
Kowa Amerian Corporation
Glucosamine hydrochloride
Odor: characteristic
Use: Glucosamine hydrochloride is a way to prepare HCL salt glucosasmine. This high purity substance is soluble in water.
Maypro Industries
Glucosamine HCL
Penta International
D-GLUCOSAMINE HYDROCHLORIDE
Sabinsa Corporation
Glucosamine HCL
Santa Cruz Biotechnology
For experimental / research use only.
D(+)Glucosamine, Hydrochloride ≥99%
Sigma-Aldrich: Sigma
For experimental / research use only.
D-(+)-Glucosamine hydrochloride ≥99%, crystalline
sds
Silver Fern Chemical
Glucosamine HCL
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
parenteral-frog LD50 5000 mg/kg
PERIPHERAL NERVE AND SENSATION: SENSORY CHANGE INVOLVING PERIPHERAL NERVE
Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 56(1), Pg. 64S, 1960.

intravenous-mouse LD50 1100 mg/kg
Chemotherapia. Vol. 5, Pg. 277, 1962.

oral-mouse LD50 15000 mg/kg
PERIPHERAL NERVE AND SENSATION: SENSORY CHANGE INVOLVING PERIPHERAL NERVE
Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 56(1), Pg. 64S, 1960.

Dermal Toxicity:
subcutaneous-mouse LD50 6200 mg/kg
PERIPHERAL NERVE AND SENSATION: SENSORY CHANGE INVOLVING PERIPHERAL NERVE
Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 56(1), Pg. 64S, 1960.

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
cosmetic agents, dietary supplements
Recommendation for glucosamine HCl usage levels up to:
 not for fragrance use.
 
Recommendation for glucosamine HCl flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
ClinicalTrials.gov:search
Daily Med:search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):66-84-2
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :91431
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
(2R,3R,4S,5R)-2-amino-3,4,5,6-tetrahydroxyhexanal;hydrochloride
Chemidplus:0000066842
RTECS:LZ6665000 for cas# 66-84-2
 
References:
 (2R,3R,4S,5R)-2-amino-3,4,5,6-tetrahydroxyhexanal;hydrochloride
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:66-84-2
Pubchem (cid):91431
Pubchem (sid):135048005
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEMBL:View
Golm Metabolome Database:Search
KEGG (GenomeNet):D08022
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2932.90.5000
FDA Listing of Food Additive Status:View
MedlinePlusSupp:View
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
 antistatic agents
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
2-amino-2-deoxy-D-glucose hydrochloride
2-amino-2-deoxy-D-glucose hydrochloride (1:1)
2-amino-2-deoxy-d-glucose hydrochloride(1:1)
(2R,3R,4S,5R)-2-amino-3,4,5,6-tetrahydroxyhexanal;hydrochloride
2-deoxy-2-amino-D-glucose hydrochloride
D-glucosamine chloride
 glucosamine HCl (low lead) 99% min.
 glucosamine HCl 95% 93.5% min
 glucosamine HCl 99%-101%
 glucosamine HCl, 99% min.
 glucosamine hydrochloride
D-glucosamine hydrochloride
D-(+)-glucosamine hydrochloride
dextro-glucosamine hydrochloride
2-glucosamine hydrochloride prepared from chitin obtained from aspergillus niger
D-glucosamine monohydrochloride
D-glucosaminehydrochloride
D-glucose, 2-amino-2-deoxy-, hydrochloride
D-glucose, 2-amino-2-deoxy-, hydrochloride (1:1)
 

Articles:

PubMed:Therapeutic Efficacy of Vitamin E δ-Tocotrienol in Collagen-Induced Rat Model of Arthritis.
PubMed:Effect of glucosamine conjugation to zinc(II) complexes of a bis-pyrazole ligand: Syntheses, characterization and anticancer activity.
PubMed:Combined glucosamine and chondroitin sulfate, once or three times daily, provides clinically relevant analgesia in knee osteoarthritis.
PubMed:Protective effects of glucosamine hydrochloride against free radical-induced erythrocytes damage.
PubMed:Effects of RU486 and indomethacin on meiotic maturation, formation of extracellular matrix, and progesterone production by porcine oocyte-cumulus complexes.
PubMed:Suppressive effects of D-glucosamine on the 5-HT sensitive nociceptive units in the rat tooth pulpal nerve.
PubMed:Short-term treatment with glucosamine hydrochloride specifically downregulates hypoxia-inducible factor-1α at the protein level in YD-8 human tongue cancer cells.
PubMed:Effect of oral glucosamine on joint structure in individuals with chronic knee pain: a randomized, placebo-controlled clinical trial.
PubMed:[Isolation of D-glucosamine from chitin-glucan complexes].
PubMed:Evaluation of arthrocentesis with hyaluronic acid injection plus oral glucosamine hydrochloride for temporomandibular joint osteoarthritis in oral-health-related quality of life.
PubMed:The dissolution enhancement of piroxicam in its physical mixtures and solid dispersion formulations using gluconolactone and glucosamine hydrochloride as potential carriers.
PubMed:Effect of Fucoxanthin Alone and in Combination with D-glucosamine Hydrochloride on Carrageenan/kaolin-induced Experimental Arthritis in Rats.
PubMed:Antioxidant and antimicrobial activity of Maillard reaction products from xylan with chitosan/chitooligomer/glucosamine hydrochloride/taurine model systems.
PubMed:NSAID-sparing effect of glucosamine hydrochloride in patients with knee osteoarthritis: an analysis of data from a French database.
PubMed:Glucosamine hydrochloride exerts a protective effect against unilateral ureteral obstruction-induced renal fibrosis by attenuating TGF-β signaling.
PubMed:Synthesis of α-amino acids from glucosamine-HCl and its derivatives by aerobic oxidation in water catalyzed by Au nanoparticles on basic supports.
PubMed:Bioavailability enhancement of glucosamine hydrochloride by chitosan.
PubMed:Nonsteroidal anti-inflammatory drugs (NSAID) sparing effects of glucosamine hydrochloride through N-glycosylation inhibition; strategy to rescue stomach from NSAID damage.
PubMed:Efficacies of different preparations of glucosamine for the treatment of osteoarthritis: a meta-analysis of randomised, double-blind, placebo-controlled trials.
PubMed:Amelioration of collagen-induced arthritis in female dark agouti rats by glucosamine treatment.
PubMed:Effect of glucosamine HCl on dissolution and solid state behaviours of piroxicam upon milling.
PubMed:Novel glucosamine hydrochloride-rectorite nanocomposites with antioxidant and anti-ultraviolet activity.
PubMed:Synthesis and evaluation of (68)Ga-labeled DOTA-2-deoxy-D-glucosamine as a potential radiotracer in μPET imaging.
PubMed:Synthesis of bacillithiol and the catalytic selectivity of FosB-type fosfomycin resistance proteins.
PubMed:Metabolomic analyses of blood plasma after oral administration of D-glucosamine hydrochloride to dogs.
PubMed:Products from microwave and ultrasonic wave assisted acid hydrolysis of chitin.
PubMed:Crystalline glucosamine sulfate in the management of knee osteoarthritis: efficacy, safety, and pharmacokinetic properties.
PubMed:Comparative fasting bioavailability and pharmacokinetic properties of 2 formulations of glucosamine hydrochloride in healthy Chinese adult male volunteers.
PubMed:[Effect of glucosamine hydrochloride in combination with paracetamol on chondrocyte apoptosis under conditions of systemic steroidal arthritis development in rats].
PubMed:Chondroitin sulfate and/or glucosamine hydrochloride for Kashin-Beck disease: a cluster-randomized, placebo-controlled study.
PubMed:Suppressive effects of N-acetyl-D-glucosamine on rheumatoid arthritis mouse models.
PubMed:Improved determination of D-glucosamine hydrochloride in health foods by HPLC using 7-fluoro-4-nitrobenzo-2-oxa-l,3-diazole as a derivative.
PubMed:A randomized comparative study of safety and efficacy of immediate release glucosamine HCL and glucosamine HCL sustained release formulation in the treatment of knee osteoarthritis: A proof of concept study.
PubMed:[Glucosamine hydrochloride combined with hyaluronate for temporomandibular joint osteoarthritis: a primary report of randomized controlled trial].
PubMed:Is there any scientific evidence for the use of glucosamine in the management of human osteoarthritis?
PubMed:[Knee osteoarthritis treated with acupuncture at the points selected according to syndrome differentiation: a randomized controlled trial].
PubMed:Kashin-Beck disease in Sichuan, China: report of a pilot open therapeutic trial.
PubMed:[Study of molecular mechanisms of fuyuan capsule, icariin and arasaponin R1 in treatment of osteoarthritis].
PubMed:Quantitation of glucosamine sulfate in plasma by HPLC-MS/MS after administration of powder for oral solution formulation.
PubMed:Anti-cancer properties of glucosamine-hydrochloride in YD-8 human oral cancer cells: Induction of the caspase-dependent apoptosis and down-regulation of HIF-1α.
PubMed:Effect of a dietary supplement containing glucosamine hydrochloride, chondroitin sulfate and quercetin glycosides on symptomatic knee osteoarthritis: a randomized, double-blind, placebo-controlled study.
PubMed:Effects of diet type and supplementation of glucosamine, chondroitin, and MSM on body composition, functional status, and markers of health in women with knee osteoarthritis initiating a resistance-based exercise and weight loss program.
PubMed:Effects of oral glucosamine hydrochloride administration on plasma free amino acid concentrations in dogs.
PubMed:Comparative therapeutic efficacy and safety of type-II collagen (UC-II), glucosamine and chondroitin in arthritic dogs: pain evaluation by ground force plate.
PubMed:Effect of π electrons on the detection of silver ions by ion-selective electrodes containing tripodal broom molecules as an ionophore.
PubMed:Oral glucosamine increases expression of transforming growth factor β1 (TGFβ1) and connective tissue growth factor (CTGF) mRNA in rat cartilage and kidney: implications for human efficacy and toxicity.
PubMed:Glucosamine-based primary amines as organocatalysts for the asymmetric aldol reaction.
PubMed:Bone resorption and remodeling in murine collagenase-induced osteoarthritis after administration of glucosamine.
PubMed:Multiple functional hyperbranched poly(amido amine) nanoparticles: synthesis and application in cell imaging.
PubMed:Efficient production of D-glucosaminic acid from D-glucosamine by Pseudomonas putida GNA5.
PubMed:Glucosamine attenuates increases of intraabdominal fat, serum leptin levels, and insulin resistance induced by a high-fat diet in rats.
PubMed:Effects of sodium-hyaluronate and glucosamine-chondroitin sulfate on remodeling stage of tenotomized superficial digital flexor tendon in rabbits: a clinical, histopathological, ultrastructural, and biomechanical study.
PubMed:High-throughput analysis of hexosamine using a colorimetric method.
PubMed:Effect of treatment based on syndrome differentiation by Chinese medicine on post-traumatic elbow arthritis.
PubMed:Glucosamine HCl as a new carrier for improved dissolution behaviour: effect of grinding.
PubMed:Comparison of glucose derivatives effects on cartilage degradation.
PubMed:Towards the assembly of heparin and heparan sulfate oligosaccharide libraries: efficient synthesis of uronic acid and disaccharide building blocks.
PubMed:Glucosamine hydrochloride functionalized tetraphenylethylene: a novel fluorescent probe for alkaline phosphatase based on the aggregation-induced emission.
PubMed:[Effect of glucosamine hydrochloride capsules on articular cartilage of rabbit knee joint in osteoarthritis].
PubMed:Identification and assessment of permeability enhancing vehicles for transdermal delivery of glucosamine hydrochloride.
PubMed:Evaluation of the effect of glucosamine on an experimental rat osteoarthritis model.
PubMed:[Safety Assessment regarding use of glucosamine sulfate by patients whose dietary potassium intake is restricted].
PubMed:Effect of glucosamine and related compounds on the degranulation of mast cells and ear swelling induced by dinitrofluorobenzene in mice.
PubMed:To enhance dissolution rate of poorly water-soluble drugs: glucosamine hydrochloride as a potential carrier in solid dispersion formulations.
PubMed:[The influence of paracetamol on the parameters of connective tissue metabolism during experimental osteoarthrosis].
PubMed:Low quality of evidence for glucosamine-based nutraceuticals in equine joint disease: review of in vivo studies.
PubMed:Glucosamine hydrochloride functionalized water-soluble conjugated polyfluorene: synthesis, characterization, and interactions with DNA.
PubMed:Differential down-regulation of COX-2 and MMP-13 in human skin fibroblasts by glucosamine-hydrochloride.
PubMed:[Determination of glucosamine hydrochloride in health foods using high performance anion exchange chromatography].
PubMed:Loss of mannosylphosphate from Candida albicans cell wall proteins results in enhanced resistance to the inhibitory effect of a cationic antimicrobial peptide via reduced peptide binding to the cell surface.
PubMed:A review of evidence-based medicine for glucosamine and chondroitin sulfate use in knee osteoarthritis.
PubMed:[Controlled clinical trials on the effects of Chinese traditional medicine for the treatment of osteoarthritis of knee joint at early stage and its MRI changes].
PubMed:Application of artificial intelligent tools to modeling of glucosamine preparation from exoskeleton of shrimp.
PubMed:Glucosamine for knee osteoarthritis--what's new?
PubMed:Synthesis of the trisaccharide repeating unit related to Klebsiella 012 serotype.
PubMed:Glucosamine increases hyaluronic acid production in human osteoarthritic synovium explants.
PubMed:Effects of methylprednisolone acetate and glucosamine on proteoglycan production by equine chondrocytes in vitro.
PubMed:Joint inflammation increases glucosamine levels attained in synovial fluid following oral administration of glucosamine hydrochloride.
PubMed:Synthesis and antiviral evaluation of some new pyrazole and fused pyrazolopyrimidine derivatives.
PubMed:Additive effects of glucosamine or risedronate for the treatment of osteoarthritis of the knee combined with home exercise: a prospective randomized 18-month trial.
PubMed:Potential glucosamine-warfarin interaction resulting in increased international normalized ratio: case report and review of the literature and MedWatch database.
PubMed:[Therapeutic results of glucosamine hydrochloride for knee degenerative osteoarthritis].
PubMed:Comparison of pharmacokinetics of glucosamine and synovial fluid levels following administration of glucosamine sulphate or glucosamine hydrochloride.
PubMed:[Determination of glucosamine hydrochloride in complex formula by RP-HPLC coupled with evaporative light scattering detection].
PubMed:Glucosamine hydrochloride for the treatment of osteoarthritis symptoms.
PubMed:Treatment of primary and secondary osteoarthritis of the knee.
PubMed:Disease-modifying effects of glucosamine HCl involving regulation of metalloproteinases and chemokines activated by interleukin-1beta in human primary synovial fibroblasts.
PubMed:[Efficacy and safety evaluation of glucosamine hydrochloride in the treatment of osteoarthritis].
PubMed:[A comparison study on the physical/chemical properties and immunomodulatory activities of mycelial polysaccharide extracts from five Ganoderma species].
PubMed:Glucosamine HCl alters production of inflammatory mediators by rat intervertebral disc cells in vitro.
PubMed:Downregulated gene expression in human palate fibroblasts after cyclosporin A treatment.
PubMed:Glucosamine prevents in vitro collagen degradation in chondrocytes by inhibiting advanced lipoxidation reactions and protein oxidation.
PubMed:Glucosamine and chondroitin sulfate as therapeutic agents for knee and hip osteoarthritis.
PubMed:Glucosamine hydrochloride specifically inhibits COX-2 by preventing COX-2 N-glycosylation and by increasing COX-2 protein turnover in a proteasome-dependent manner.
PubMed:Glucosamine for pain in osteoarthritis: why do trial results differ?
PubMed:Glucosamine/chondroitin combined with exercise for the treatment of knee osteoarthritis: a preliminary study.
PubMed:Collagen Synthesis in tenocytes, ligament cells and chondrocytes exposed to a combination of Glucosamine HCl and chondroitin sulfate.
PubMed:Glucosamine reduces anabolic as well as catabolic processes in bovine chondrocytes cultured in alginate.
PubMed:The effects of glucosamine hydrochloride on subchondral bone changes in an animal model of osteoarthritis.
PubMed:Establishment of a novel corneal endothelial cell line from domestic rabbit, Oryctolagus curiculus.
PubMed:Glucosamine inhibits LPS-induced COX-2 and iNOS expression in mouse macrophage cells (RAW 264.7) by inhibition of p38-MAP kinase and transcription factor NF-kappaB.
PubMed:Double blind investigation of the effects of oral supplementation of combined glucosamine hydrochloride (GHCL) and chondroitin sulphate (CS) on stride characteristics of veteran horses.
PubMed:Modulation of articular chondrocyte proliferation and anionic glycoconjugate synthesis by glucosamine (GlcN), N-acetyl GlcN (GlcNAc) GlcN sulfate salt (GlcN.S) and covalent glucosamine sulfates (GlcN-SO4).
PubMed:Preparation of glucosamine from exoskeleton of shrimp and predicting production yield by response surface methodology.
PubMed:Systematic review of clinical trials of treatments for osteoarthritis in dogs.
PubMed:[The influence of experimental therapy on the dynamics of endogenous glucosamine content in laboratory animals with nephropathy].
PubMed:Therapeutic Efficacy and Safety of Undenatured Type II Collagen Singly or in Combination with Glucosamine and Chondroitin in Arthritic Dogs.
PubMed:Evidence-based practice: review of clinical evidence on the efficacy of glucosamine and chondroitin in the treatment of osteoarthritis.
PubMed:Arthritic disease suppression and cartilage protection with glycosaminoglycan polypeptide complexes (Peptacans) derived from the cartilage extracellular matrix: a novel approach to therapy.
PubMed:Effects of glucosamine administration on patients with rheumatoid arthritis.
PubMed:Antitumor activities of D-glucosamine and its derivatives.
PubMed:Randomised double-blind, positive-controlled trial to assess the efficacy of glucosamine/chondroitin sulfate for the treatment of dogs with osteoarthritis.
PubMed:[Experience with glucosamine hydrochloride in the treatment of patients with osteoarthrosis].
PubMed:Determination of the degree of acetylation of chitosan by UV spectrophotometry using dual standards.
PubMed:An optimized reverse-phase high performance liquid chromatographic method for evaluating percutaneous absorption of glucosamine hydrochloride.
PubMed:[Combined medication ARTRA in the treatment of osteoarthrosis].
PubMed:Inhibitory action of glucosamine on platelet activation in guinea pigs.
PubMed:[A multi-central, randomized, controlled clinical trial of glucosamine hydrochloride/sulfate in the treatment of knee osteoarthritis].
PubMed:Chitosan monomer promotes tissue regeneration on dental pulp wounds.
PubMed:Glucosamine decreases expression of anabolic and catabolic genes in human osteoarthritic cartilage explants.
PubMed:The antioxidant activity of glucosamine hydrochloride in vitro.
PubMed:Determination of glucosamine in raw materials and dietary supplements containing glucosamine sulfate and/or glucosamine hydrochloride by high-performance liquid chromatography with FMOC-Su derivatization: collaborative study.
PubMed:[Study on D-glucosamine-zn (II) complexes by IR spectral analysis].
PubMed:Fursultiamine, a vitamin B1 derivative, enhances chondroprotective effects of glucosamine hydrochloride and chondroitin sulfate in rabbit experimental osteoarthritis.
PubMed:Classification of chondroitin sulfate A, chondroitin sulfate C, glucosamine hydrochloride and glucosamine 6 sulfate using chemometric techniques.
PubMed:Effects of glucosamine hydrochloride and chondroitin sulphate, alone and in combination, on normal and interleukin-1 conditioned equine articular cartilage explant metabolism.
PubMed:Effect of oral glucosamine on cartilage degradation in a rabbit model of osteoarthritis.
PubMed:A solid-state NMR application of the anomeric effect in carbohydrates: galactosamine, glucosamine, and N-acetyl-glucosamine.
PubMed:[NMR study on the determination of structure in the protected glucosamineoside].
PubMed:13C solid-state NMR chemical shift anisotropy analysis of the anomeric carbon in carbohydrates.
PubMed:Synovial fluid levels and serum pharmacokinetics in a large animal model following treatment with oral glucosamine at clinically relevant doses.
PubMed:Recent advances in glucosamine and chondroitin supplementation.
PubMed:OK205 regulates production of inflammatory cytokines in HMC-1 cells.
PubMed:Single laboratory validation of a method for determination of glucosamine in raw materials and dietary supplements containing glucosamine sulfate and/or glucosamine hydrochloride by high-performance liquid chromatography with FMOC-Su derivatization.
PubMed:Formation and properties of positively charged colloids based on polyelectrolyte complexes of biopolymers.
PubMed:Effects of glucosamine hydrochloride on the production of prostaglandin E2, nitric oxide and metalloproteases by chondrocytes and synoviocytes in osteoarthritis.
PubMed:A stability-indicating HPLC method for the determination of glucosamine in pharmaceutical formulations.
PubMed:The bioavailability and pharmacokinetics of glucosamine hydrochloride and chondroitin sulfate after oral and intravenous single dose administration in the horse.
PubMed:[Study on the role of glucosamine hydrochloride in the pathogenesis of osteoarthritis].
PubMed:The effect of exogenous glucosamine hydrochloride on the proteoglycan concentration of the articular disc of the rabbit temporomandibular joint.
PubMed:The effect of glucosamine-chondroitin supplementation on glycosylated hemoglobin levels in patients with type 2 diabetes mellitus: a placebo-controlled, double-blinded, randomized clinical trial.
PubMed:Reduction mechanism of tetrazolium salt XTT by a glucosamine derivative.
PubMed:Fibrin D-dimer impairs the accumulation and anticoagulant properties of heparan sulphate and stimulates secretion of plasminogen activator inhibitor-1 by rabbit coronary endothelial cells.
PubMed:[Experimental study of the effect of glucosamine hydrochloride on metabolic and repair processes in connective tissue structures].
PubMed:Synthesis and induction of apoptosis in B cell chronic leukemia by diosgenyl 2-amino-2-deoxy-beta-D-glucopyranoside hydrochloride and its derivatives.
PubMed:Preformulation studies and characterization of proposed chondroprotective agents: glucosamine HCl and chondroitin sulfate.
PubMed:Inhibition of articular cartilage degradation by glucosamine-HCl and chondroitin sulphate.
PubMed:High doses of glucosamine-HCl have detrimental effects on bovine articular cartilage explants cultured in vitro.
PubMed:The bioavailability and pharmacokinetics of glucosamine hydrochloride and low molecular weight chondroitin sulfate after single and multiple doses to beagle dogs.
PubMed:Serum concentrations of keratan sulfate, osteocalcin, and pyridinoline crosslinks after oral administration of glucosamine to standardbred horses during race training.
PubMed:Protective effect of the chondroprotective agent Cosequin DS on bovine articular cartilage exposed in vitro to nonsteroidal antiinflammatory agents.
PubMed:A randomized double-blind clinical trial of the effect of chondroitin sulfate and glucosamine hydrochloride on temporomandibular joint disorders: a pilot study.
PubMed:A hydrogen-bonding receptor that binds cationic monosaccharides with high affinity in methanol.
PubMed:Safety of an oral chondroprotective agent in horses.
PubMed:Effect of pre-loading oral glucosamine HCl/chondroitin sulfate/manganese ascorbate combination on experimental arthritis in rats.
PubMed:Increasing the intra-Golgi pH of cultured LS174T goblet-differentiated cells mimics the decreased mucin sulfation and increased Thomsen-Friedenreich antigen (Gal beta1-3GalNac alpha-) expression seen in colon cancer.
PubMed:Oral treatment with a nutraceutical (Cosequin) for ameliorating signs of navicular syndrome in horses.
PubMed:Effects of an orally administered mixture of chondroitin sulfate, glucosamine hydrochloride and manganese ascorbate on synovial fluid chondroitin sulfate 3B3 and 7D4 epitope in a canine cruciate ligament transection model of osteoarthritis.
PubMed:In vivo chondroprotection and metabolic synergy of glucosamine and chondroitin sulfate.
PubMed:The effects of glucosamine derivatives on equine articular cartilage degradation in explant culture.
PubMed:Secretion of paracrine factors enabling expansion of cumulus cells is developmentally regulated in pig oocytes.
PubMed:A novel amphiphilic chiral ligand derived from D-glucosamine. Application to palladium-catalyzed asymmetric allylic substitution reaction in an aqueous or an organic medium, allowing for catalyst recycling
PubMed:Efficacy of a combination of FCHG49 glucosamine hydrochloride, TRH122 low molecular weight sodium chondroitin sulfate and manganese ascorbate in the management of knee osteoarthritis.
PubMed:Glucosamine HCl reduces equine articular cartilage degradation in explant culture.
PubMed:The effects of aspirin on antioxidant defences of cultured rat gastric mucosal cells.
PubMed:Determination of the nutraceutical, glucosamine hydrochloride, in raw materials, dosage forms and plasma using pre-column derivatization with ultraviolet HPLC.
PubMed:Scintigraphic evaluation of dogs with acute synovitis after treatment with glucosamine hydrochloride and chondroitin sulfate.
PubMed:Effect of glucosamine hydrochloride in the treatment of pain of osteoarthritis of the knee.
PubMed:Oocytectomy does not influence synthesis of hyaluronic acid by pig cumulus cells: retention of hyaluronic acid after insulin-like growth factor-I treatment in serum-free medium.
PubMed:Access to tetrachlorophthalimide-protected ethyl 2-amino-2-deoxy-1-thio-beta-D-glucopyranosides.
PubMed:Glucosamine, chondroitin, and manganese ascorbate for degenerative joint disease of the knee or low back: a randomized, double-blind, placebo-controlled pilot study.
PubMed:Chemical, metabolic and immunological characterization of gangliosides of human glioma cells.
PubMed:Establishment and characterization of tracheal epithelial cell lines, TM01 and TM02-3, from transgenic mice bearing temperature-sensitive simian virus 40 large T-antigen gene.
PubMed:A carbon-centered radical as a reaction species in the DNA strand-breakage by D-glucosamine.
PubMed:Synthesis of substituted chiral piperazones resembling aza-sugars.
PubMed:Dexamethasone treatment decreases hyaluronan-formation by primate trabecular meshwork cells in vitro.
PubMed:Possible involvement of dihydrofructosazine in the DNA breaking activity of D-glucosamine.
PubMed:Effects of hexoses and their derivatives on glucagon secretion from isolated perfused rat pancreas.
PubMed:Chirospecific synthesis of D and Lp-chlorohomophenylalanine N-t-BOC DCHA salts.
PubMed:[Soluble and semisoluble lectins from mollicutes and their possible functions].
PubMed:Elevated levels of glycoprotein gp200 in progeria fibroblasts.
PubMed:Nonenzymatic modifications of amino sugars in vitro.
PubMed:Formation of pyrazine derivatives from D-glucosamine and their deoxyribonucleic acid (DNA) strand breakage activity.
PubMed:[The efficacy of glucosamine in treating complicated hyperreactive experimental myocardial infarct].
PubMed:Post-translational alterations in newly synthesized cartilage proteoglycans induced by the glutamine analogue 6-diazo-5-oxo-L-norleucine. Time course of inhibition and recovery.
PubMed:Cartilage changes in rats induced by papain and the influence of treatment with N-acetylglucosamine.
PubMed:Mast cell heterogeneity. Differential synthesis and expression of glycosphingolipids by mouse serosal mast cells as compared to IL-3-dependent bone marrow culture-derived mast cells before or after coculture with 3T3 fibroblasts.
PubMed:Purification and characterization of bacteriophage receptor on Veillonella rodentium cells. Phage-receptor on Veillonella.
PubMed:Effect of sulfate concentration on glycosaminoglycan synthesis in explant cultures of bovine articular cartilage.
PubMed:Oxygen radicals stimulate guinea pig gallbladder glycoprotein secretion in vitro.
PubMed:Sporulation media for Basidiobolus species.
PubMed:Monoclonal antibodies to human renal cell carcinoma: recognition of shared and restricted tissue antigens.
PubMed:A convergent approach to the synthesis of lipid A.
PubMed:N-acetylneuraminic acid and sialoglycoconjugate metabolism in fibroblasts from a patient with generalized N-acetylneuraminic acid storage disease.
PubMed:[Effect of hexosamine derivatives on mesenchymal metabolic processes of in vitro cultured fetal bone explants].
PubMed:Neurophysin biosynthesis in vitro in oat cell carcinoma of the lung with ectopic vasopressin production.
PubMed:The permeability of endplate channels to monovalent and divalent metal cations.
PubMed:Secretory response of dispersed rat submandibular cells. II. Mucin secretion.
PubMed:Characteristics of Streptomyces coelicolor A3(2) aerial spore rodlet mosaic.
PubMed:[Effect of peptidoglycan preparations on phage inactivation: decrease in phage 187 binding using monosaccharides].
PubMed:Isolation of glycopeptides from the lectin-stimulated human peripheral lymphocyte cell surface.
PubMed:Alkyl streptozotocin analogues with improved biological activities.
PubMed:Glucosamine-labelled envelope proteins of Escherichia coli K-12. I. Electrophoretic studies and partial fractionation of phenol-soluble proteins.
PubMed:On the mode of action of hydroxyproline in Drosophila development.
PubMed:Selective inhibition of Newcastle disease virus-induced glycoprotein synthesis by D-glucosamine hydrochloride.
PubMed:Glucosamine HCl, hydroxyproline and developmental homoeostasis in Drosophila melanogaster.
PubMed:Cold osmotic shock in Saccharomyces cerevisiae.
PubMed:The effect of exogenously administered D-glucosamine hydrochloride on the seromucoid fraction of tumor-bearing rats.
PubMed:Mannosyl D-glucosamine hydrochloride isomers.
PubMed:The influence of glucosamine-hydrochloride on cellular adhesiveness in Drosophila melanogaster.
PubMed:[Chemotherapy of experimental schistosomiasis. 2. Observations on the therapeutic action of glucosamine hydrochloride].
PubMed:[Tumor inhibiting effect of basic substance components (especially glucosamine hydrochloride)].
PubMed:Enhancement of tetracycline serum levels with glucosamine hydrochloride as adjuvant; cross-over studies in beagle dogs.
PubMed:The fate of glucosamine hydrochloride injected intravenously in man.
PubMed:Radioactive oxytetracycline (terramycin). III. Effect of glucosamine HCL on serum concentrations.
PubMed:The effect of D-glucosamine hydrochloride and related compounds on tissue cultures of the solid form of mouse sarcoma 37.
PubMed:d-Glucosamine hydrochloride.
 
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