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Category:natural substances and extractives
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| | FDA/DG SANTE Petitions, Reviews, Notices: |
| FR DOC # 2012-4164 | International Conference on Harmonisation; Final Recommendation for the Revision of the Permitted Daily Exposure for the Solvent Cumene According to the Maintenance Procedures for the Guidance Q3C Impurities: Residual So View - petition PDF |
Physical Properties:
| Appearance: | colorless to pale yellow clear liquid (est) |
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 0.86400 @ 25.00 °C.
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| Refractive Index: | 1.48460 @ 20.00 °C.
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| Boiling Point: | 152.00 to 153.00 °C. @ 760.00 mm Hg
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| Vapor Pressure: | 4.500000 mmHg @ 25.00 °C. |
| Flash Point: | 115.00 °F. TCC ( 46.11 °C. )
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| logP (o/w): | 3.660 |
| Soluble in: |
| | alcohol | | | water, 61.3 mg/L @ 25 °C (exp) |
| Insoluble in: |
| | water |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-rat LD50 1400 mg/kg
GASTROINTESTINAL: GASTRITIS
AMA Archives of Industrial Health. Vol. 14, Pg. 387, 1956.
oral-mouse LD50 12750 mg/kg
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 36(9), Pg. 18, 1971.
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| Dermal Toxicity: |
skin-rabbit LD50 12300 ul/kg
AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 4, Pg. 119, 1951.
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| Inhalation Toxicity: |
inhalation-mouse LC50 10000 mg/m3/7H
BLOOD: CHANGES IN SPLEEN
LIVER: MULTIPLE EFFECTS
KIDNEY, URETER, AND BLADDER: CHANGES IN BOTH TUBULES AND GLOMERULI
Journal of Industrial Hygiene and Toxicology. Vol. 26, Pg. 264, 1944.
inhalation-human TCLo 200 ppm
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: ANTIPSYCHOTIC
BEHAVIORAL: IRRITABILITY
"Handbook of Organic Industrial Solvents," 2nd ed., Chicago, National Assoc. of Mutual Casualty Companies, 1961Vol. 2, Pg. 39, 1961.
inhalation-rat LCLo 8000 ppm/4H
AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 4, Pg. 119, 1951.
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Safety in Use Information:
| Category: | | natural substances and extractives |
| Recommendation for cumene usage levels up to: | | | not for fragrance use.
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| Recommendation for cumene flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | benzene, (1-methylethyl)- | | | benzene, 1-methylethyl- | | | benzene, isopropyl | | ( | methylethyl)benzene | | (1- | methylethyl)benzene | | 2- | phenylpropane | | ( | propan-2-yl)benzene | | iso | propylbenzene |
Articles:
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Trace constit. of ginger oil (Zingiber officinale)
Cumene is the common name for isopropylbenzene, an organic compound that is an aromatic hydrocarbon. It is a constituent of crude oil and refined fuels. It is a flammable colorless liquid that has a boiling point of 152 °C. Nearly all the cumene that is produced as a pure compound on an industrial scale is converted to cumene hydroperoxide, which is an intermediate in the synthesis of other industrially important chemicals such as phenol and acetone.
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3D/inchi