EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

chloroacetic acid
acetic acid, 2-chloro-

Supplier Sponsors

Name:2-chloroacetic acid
CAS Number: 79-11-8Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:201-178-4
FDA UNII: 5GD84Y125G
Nikkaji Web:J2.409K
Beilstein Number:0605438
MDL:MFCD00002683
XlogP3:0.20 (est)
Molecular Weight:94.49631000
Formula:C2 H3 Cl O2
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:keratolytic agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
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PubMed:Search
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FDA Mainterm (SATF):79-11-8 ; MONOCHLOROACETIC ACID--PROHIBITED
FDA Regulation:
FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS
Subpart B--Substances for Use Only as Components of Adhesives
Sec. 175.105 Adhesives.


FDA PART 189 -- SUBSTANCES PROHIBITED FROM USE IN HUMAN FOOD
Subpart C--Substances Generally Prohibited From Direct Addition or Use as Human Food
Sec. 189.155 Monochloroacetic acid.
 
Physical Properties:
Food Chemicals Codex Listed: No
Melting Point: 61.00 to 63.00 °C. @ 760.00 mm Hg
Boiling Point: 187.00 to 190.00 °C. @ 760.00 mm Hg
Boiling Point: 115.00 to 116.00 °C. @ 50.00 mm Hg
Vapor Pressure:0.065000 mmHg @ 25.00 °C.
logP (o/w): 0.220
Soluble in:
 water, 858000 mg/L @ 25 °C (exp)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: keratolytics
 
Suppliers:
Covalent Chemical
Chloroacetic Acid
EMD Millipore
For experimental / research use only.
Chloroacetic Acid
Glentham Life Sciences
Chloroacetic acid
Santa Cruz Biotechnology
For experimental / research use only.
Chloroacetic Acid ≥99%
Sigma-Aldrich
For experimental / research use only.
Chloroacetic Acid ACS reagent, ≥99.0%
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 55 mg/kg
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 18(9), Pg. 32, 1974.

intraperitoneal-rat LD50 16.60 mg/kg
Russian Pharmacology and Toxicology Vol. 41, Pg. 113, 1978.

intraperitoneal-rat LD50 16600 ug/kg
Russian Pharmacology and Toxicology Vol. 41, Pg. 113, 1978.

Dermal Toxicity:
subcutaneous-rat LD50 5 mg/kg
Toxicology and Applied Pharmacology. Vol. 22, Pg. 303, 1972.

subcutaneous-mouse LD50 250 mg/kg
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 116, Pg. 154, 1958.

Inhalation Toxicity:
inhalation-rat LC50 180 mg/m3
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 18(9), Pg. 32, 1974.

 
Safety in Use Information:
Category:
keratolytic agents
Recommendation for chloroacetic acid usage levels up to:
 not for fragrance use.
 
Recommendation for chloroacetic acid flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
NIOSH International Chemical Safety Cards:search
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
Carcinogenic Potency Database:Search
EPA GENetic TOXicology:Search
EPA Substance Registry Services (TSCA):79-11-8
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :300
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
2-chloroacetic acid
Chemidplus:0000079118
EPA/NOAA CAMEO:hazardous materials
RTECS:79-11-8
 
References:
 2-chloroacetic acid
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:79-11-8
Pubchem (cid):300
Pubchem (sid):134971249
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
CHEBI:View
CHEMBL:View
Metabolomics Database:Search
UM BBD:Search
KEGG (GenomeNet):C06755
HMDB (The Human Metabolome Database):HMDB31331
FooDB:FDB003394
Export Tariff Code:2915.40.1000
Wikipedia:View
Formulations/Preparations:
•grades: technical; medicinal; 99.5% pure. •80% solution of chloroacetic acid •mcaa is marketed as a powder or flakes, as a concentrated solution in water, methanol or ethanol, but also in molten form, as its na-salt or as the methyl ester .
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 acetic acid, 2-chloro-
monochloracetic acid
2-chloro-acetic acid
2-chloro-ethanoic acid
2-chloroacetic acid
alpha-chloroacetic acid
 chloroacetic acid, molten [UN3250] [Poison]
 chloroacetic acid, solid [UN1751] [Poison]
 chloroacetic acid, solution [UN1750] [Poison]
 chloroethanoic acid
monochloroethanoic acid
 

Articles:

PubMed:SYNTHESIS AND ANTIMICROBIAL EVALUATION OF CYANOPYRIDINYL TETRAHYDRONAPHTHALENE DERIVATIVES.
PubMed:Reverse Engineering of Conjugated Microporous Polymers: Defect Structures of Tetrakis(4-ethynylphenyl)stannane Networks.
PubMed:Synthesis of Some Novel Heterocyclic and Schiff Base Derivatives as Antimicrobial Agents.
PubMed:Design, Synthesis, Characterization and Antimicrobial Evaluation of Some Heterocyclic Condensed Systems with Bridgehead Nitrogen from Thiazolotriazole Class.
PubMed:In Vitro Cytotoxicity and Adaptive Stress Responses to Selected Haloacetic Acid and Halobenzoquinone Water Disinfection Byproducts.
PubMed:Comparative cytotoxic and genotoxic potential of 13 drinking water disinfection by-products using a microplate-based cytotoxicity assay and a developed SOS/umu assay.
PubMed:Highly effective removal of Methylene Blue using functionalized attapulgite via hydrothermal process.
PubMed:[To the question of the optimization of methods for detection of vinyl chloride and 1,2-dichloroethane, and their metabolites in biological fluids in workers involved in production of polyvinyl chloride].
PubMed:Optimized synthesis of O-carboxymethyl-N,N,N-trimethyl chitosan.
PubMed:Synthesis of cyclopropyl-substituted furans by brønsted Acid promoted cascade reactions.
PubMed:Effect of drinking water disinfection by-products in human peripheral blood lymphocytes and sperm.
PubMed:Effect of dissolved oxygen concentration on iron efficiency: Removal of three chloroacetic acids.
PubMed:Antioxidant Activity and Gas Chromatographic-Mass Spectrometric Analysis of Extracts of the Marine Algae, Caulerpa peltata and Padina Gymnospora.
PubMed:Monochloroacetic acid application is an effective alternative to cryotherapy for common and plantar warts in primary care: a randomized controlled trial.
PubMed:Determination of selected protoporphyrins in parma ham with use of 5,10,15,20-tetra(4-hydroxyphenyl)porphyrin as a surrogate standard in the recovery study.
PubMed:Predictive capability of chlorination disinfection byproducts models.
PubMed:Chloroacetic acid triggers apoptosis in neuronal cells via a reactive oxygen species-induced endoplasmic reticulum stress signaling pathway.
PubMed:Preparation and properties of polyester fabrics grafted with O-carboxymethyl chitosan.
PubMed:Novel benzoxazine-based aglycones block glucose uptake in vivo by inhibiting glycosidases.
PubMed:Kinetics and efficiency of the hydrated electron-induced dehalogenation by the sulfite/UV process.
PubMed:Synthesis and preliminary ex vivo evaluation of the spasmolytic activity of 1,3-thiazolium- and 1,3,4-thiadiazolium-5-methylthio- and 5-thioacetate derivatives.
PubMed:[Influencing factors and reaction mechanism of chloroacetic acid reduction by cast iron].
PubMed:Bioanalytical and chemical evaluation of disinfection by-products in swimming pool water.
PubMed:Impurity profiling of carbocisteine by HPLC-CAD, qNMR and UV/vis spectroscopy.
PubMed:Transformation efficiency and formation of transformation products during photochemical degradation of TCE and PCE at micromolar concentrations.
PubMed:Short peptide tag for covalent protein labeling based on coiled coils.
PubMed:Investigation of adsorption capacity of N-carboxymethyl chitosan for Pb(II) ions.
PubMed:Carboxymethyl inulin: a novel flocculant for wastewater treatment.
PubMed:Human cell toxicogenomic analysis linking reactive oxygen species to the toxicity of monohaloacetic acid drinking water disinfection byproducts.
PubMed:Comparative developmental toxicity of new aromatic halogenated DBPs in a chlorinated saline sewage effluent to the marine polychaete Platynereis dumerilii.
PubMed:A convenient and sensitive method for haloacetic acid analysis in tap water by on-line field-amplified sample-stacking CE-ESI-MS.
PubMed:Synthesis and characterization of N-(2-aminoethyl)-2-acetamidyl gellan gum with potential biomedical applications.
PubMed:Characterisation of an L-haloacid dehalogenase from the marine psychrophile Psychromonas ingrahamii with potential industrial application.
PubMed:Pyruvate remediation of cell stress and genotoxicity induced by haloacetic acid drinking water disinfection by-products.
PubMed:Identification and analysis of an impurity inducing clinical adverse effect in anti-adhesion carboxymethyl chitosan products.
PubMed:Tuning affinity and reversibility for O2 binding in dinuclear Co(II) complexes.
PubMed:A facile synthesis, anti-inflammatory and analgesic activity of isoxazolyl-2,3-dihydrospiro[benzo[f]isoindole-1,3'-indoline]-2',4,9-triones.
PubMed:Organocatalysis in heterocyclic synthesis: DABCO as a mild and efficient catalytic system for the synthesis of a novel class of quinazoline, thiazolo [3,2-a]quinazoline and thiazolo[2,3-b] quinazoline derivatives.
PubMed:Genotoxic and clastogenic effects of monohaloacetic acid drinking water disinfection by-products in primary human lymphocytes.
PubMed:Enhanced degradation of haloacid by heterologous expression in related Burkholderia species.
PubMed:[Formation of disinfection by-products: temperature effect and kinetic modeling].
PubMed:Thiazolidinediones : A class of pharmacologically important molecules.
PubMed:A further study of acetylacetone nitrosation.
PubMed:Transports of acetate and haloacetate in Burkholderia species MBA4 are operated by distinct systems.
PubMed:Chloroacetic acid induced neuronal cells death through oxidative stress-mediated p38-MAPK activation pathway regulated mitochondria-dependent apoptotic signals.
PubMed:Ethylenediammonium dication: H-bonded complexes with terephthalate, chloroacetate, phosphite, selenite and sulfamate anions. Detailed vibrational spectroscopic and theoretical studies of ethylenediammonium terephthalate.
PubMed:Synthesis, characterization and in vitro release behavior of carboxymethyl xanthan.
PubMed:Removal of Cu(II) ions from aqueous solutions using N-carboxymethyl chitosan.
PubMed:A convenient ultrasound-promoted synthesis of some new thiazole derivatives bearing a coumarin nucleus and their cytotoxic activity.
PubMed:Synthesis, characterization and structure optimization of a series of thiazolidinone derivatives as Entamoeba histolytica inhibitors.
PubMed:Efficient reductive dechlorination of monochloroacetic acid by sulfite/UV process.
PubMed:The hdhA gene encodes a haloacid dehalogenase that is regulated by the LysR-type regulator, HdhR, in Sinorhizobium meliloti.
PubMed:Novel insights in Al-MCM-41 precursor as adsorbent for regulated haloacetic acids and nitrate from water.
PubMed:Enantioselective direct aldol reaction of α-keto esters catalyzed by (S(a))-binam-D-prolinamide under quasi solvent-free conditions.
PubMed:N-(4-18F-fluorobenzoyl)interleukin-2 for PET of human-activated T lymphocytes.
PubMed:Synthesis and characterization of carboxymethyl chitosan hydrogel: application as pH-sensitive delivery for nateglinide.
PubMed:Lipases as catalysts in synthesis of fine chemicals.
PubMed:Maternal exposure to drinking-water chlorination by-products and small-for-gestational-age neonates.
PubMed:Analysis of haloacetic acids in water and air (aerosols) from indoor swimming pools using HS-SPME/GC/ECD.
PubMed:Development of a method for the quantitation of chloro-, bromo-, and iodoacetic acids in alcoholic beverages.
PubMed:Characterization of intracellular & extracellular algae organic matters (AOM) of Microcystic aeruginosa and formation of AOM-associated disinfection byproducts and odor & taste compounds.
PubMed:Chitosan microparticles and nanoparticles as biocompatible delivery vehicles for peptide and protein-based immunocontraceptive vaccines.
PubMed:Isolation and characterization of monochloroacetic acid-degrading bacteria.
PubMed:Comparison of DNA damage in human-derived hepatoma line (HepG2) exposed to the fifteen drinking water disinfection byproducts using the single cell gel electrophoresis assay.
PubMed:Electromembrane extraction and HPLC analysis of haloacetic acids and aromatic acetic acids in wastewater.
PubMed:Hydrazonoyl halides as precursors for new fused heterocycles of 5α-reductase inhibitors.
PubMed:Preparation of cross-linked carboxymethyl jackfruit starch and evaluation as a tablet disintegrant.
PubMed:[Chlorination byproducts formation potentials of typical nitrogenous organic compounds in water].
PubMed:Comparative electrochemical treatments of two chlorinated aliphatic hydrocarbons. Time course of the main reaction by-products.
PubMed:Nanosized silica modified with carboxylic acid as support for controlled release of herbicides.
PubMed:Biological mechanism for the toxicity of haloacetic acid drinking water disinfection byproducts.
PubMed:Paclitaxel conjugation with the analog of the gonadotropin-releasing hormone as a targeting moiety.
PubMed:Synthesis, antitumor activity and molecular docking study of novel benzofuran-2-yl pyrazole pyrimidine derivatives.
PubMed:Mixture toxicity of S(N)2-reactive soft electrophiles: 2-evaluation of mixtures containing ethyl α-halogenated acetates.
PubMed:In vitro and in vivo evaluation of chemically modified degradable starch microspheres for topical haemostasis.
PubMed:Synthesis, antihypertensive activity, and 3D-QSAR studies of some new p-hydroxybenzohydrazide derivatives.
PubMed:[Establishment of an erythroleukemia model in CB6F1 mice by transplant with haploidentical mouse leukemic cell line FBL-3].
PubMed:[Investigation on coal work's production use of chloroacetic acid in one province].
PubMed:Synthesis and biological evaluation of some nitrogen containing steroidal heterocycles.
PubMed:Mammalian cell cytotoxicity and genotoxicity of the haloacetic acids, a major class of drinking water disinfection by-products.
PubMed:Assessment of the cytotoxicity and genotoxicity of haloacetic acids using microplate-based cytotoxicity test and CHO/HGPRT gene mutation assay.
PubMed:Effects of chlorinated acetates on the glutathione metabolism and on glycolysis of cultured astrocytes.
PubMed:Genotoxicity testing of three monohaloacetic acids in TK6 cells using the cytokinesis-block micronucleus assay.
PubMed:Preparation, characterization and adsorption performance of a novel anionic starch microsphere.
PubMed:Cytotoxicity and utility of 1-indanone in the synthesis of some new heterocycles.
PubMed:Quantification of monofluoroacetate and monochloroacetate in human urine by isotope dilution liquid chromatography tandem mass spectrometry.
PubMed:New 6-amino-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines and [1,2,4]triazolo[3,4-b] [1,3,4]thiadiazin-6-ones: synthesis, characterization and antibacterial activity evaluation.
PubMed:Synthesis of 3-((2,4-dichlorophenoxy)methyl)-1,2,4-triazolo(thiadiazoles and thiadiazines) as anti-inflammatory and molluscicidal agents.
PubMed:Impregnation of tubular self-assemblies into dextran hydrogels.
PubMed:Synthesis of novel celluloses derivatives and investigation of their mitogenic activity in the presence and absence of FGF2.
PubMed:Mammalian cell DNA damage and repair kinetics of monohaloacetic acid drinking water disinfection by-products.
PubMed:Hexane-1,6-diaminium chloride [hydrogen bis(chloroacetate)].
PubMed:CE-ESI-MS analysis of singly charged inorganic and organic anions using a dicationic reagent as a complexing agent.
PubMed:Reduction of protons assisted by a hexanuclear nickel thiolate metallacrown: protonation and electrocatalytic dihydrogen evolution.
PubMed:Oxidation of glycerol to glycolate by using supported gold and palladium nanoparticles.
PubMed:Effect of zinc on the transformation of haloacetic acids (HAAs) in drinking water.
PubMed:The determination of haloacetic acids in real world samples using IC-ESI-MS-MS.
PubMed:Theoretical analysis of kinetic isotope effects on proton transfer reactions between substituted alpha-methoxystyrenes and substituted acetic acids.
PubMed:Functional groups affect physical and biological properties of dextran-based hydrogels.
PubMed:Effective removal of disinfection by-products and assimilable organic carbon: an advanced water treatment system.
PubMed:Carboxymethyl Chinese yam starch: synthesis, characterization, and influence of reaction parameters.
PubMed:From proton nuclear magnetic resonance spectra to pH. Assessment of 1H NMR pH indicator compound set for deuterium oxide solutions.
PubMed:Self-assembly of chemically engineered hydrophilic dextran into microscopic tubules.
PubMed:[Determination of the electrophoretic mobility of peripheral red blood cells from healthy individuals, by using ethylene-2-amine-4-chloroacetic acid as a preservative].
PubMed:Preparation and application of carboxymethyl yam (Dioscorea esculenta) starch.
PubMed:Application of capillary affinity electrophoresis and density functional theory to the investigation of valinomycin-lithium complex.
PubMed:X-Ray crystallographic and mutational studies of fluoroacetate dehalogenase from Burkholderia sp. strain FA1.
PubMed:Capillary affinity electrophoresis and ab initio calculation studies of valinomycin complexation with Na+ ion.
PubMed:An unusual and serious complication of topical wart treatment with monochloroacetic acid.
PubMed:Reactions of pyrimidinonethione derivatives: Synthesis of 2-hydrazinopyrimidin-4-one, pyrimido[1,2-a]-1,2,4-triazine, triazolo-[1,2-a]pyrimidine, 2-(1-pyrazolo)pyrimidine and 2-arylhydrazonopyrimidine derivatives.
PubMed:Experimental design for the study of two derivatization procedures for simultaneous GC analysis of acidic herbicides and water chlorination by-products.
PubMed:Adsorptive stripping voltammetric determination of antimony.
PubMed:Photobactericidal plastic films based on cellulose esterified by chloroacetate and a cationic porphyrin.
PubMed:Simultaneous liquid-liquid microextraction/methylation for the determination of haloacetic acids in drinking waters by headspace gas chromatography.
PubMed:Dechlorination of disinfection by-product monochloroacetic acid in drinking water by nanoscale palladized iron bimetallic particle.
PubMed:Helical tubuland diols: a synthetic and crystal engineering quest.
PubMed:Substituted 2-nitrobenzyltrichloroacetate esters for photodirected oligonucleotide detritylation in solid films.
PubMed:[Study advance on reproductive and developmental toxicity of haloacetic acids in drinking water].
PubMed:Haloacetic acid and trihalomethane formation from the chlorination and bromination of aliphatic beta-dicarbonyl acid model compounds.
PubMed:Engineering a catabolic pathway in plants for the degradation of 1,2-dichloroethane.
PubMed:Effect of introduced charge in cellulose gels on surface interactions and the adsorption of highly charged cationic polyelectrolytes.
PubMed:Synthesis of novel cationic bolaamphiphiles from vernonia oil and their aggregated structures.
PubMed:Synthesis, molecular structure and spectral properties of quaternary ammonium derivatives of 1,1-dimethyl-1,3-propylenediamine.
PubMed:High performance ion chromatography of haloacetic acids on macrocyclic cryptand anion exchanger.
PubMed:Synthesis and characteristics of macroporous epoxy resin-triethylenetetramine polymer modified by sodium chloroacetate for copper chelation in aqueous solution.
PubMed:Compressed hydrogen-bond effects in the pressure-frozen chloroacetic acid.
PubMed:Seasonal variations of disinfection by-product precursors profile and their removal through surface water treatment plants.
PubMed:One-pot synthesis of 5-arylidene-2-imino-4-thiazolidinones under microwave irradiation.
PubMed:On-line solid-phase extraction with a monolithic weak cation-exchange column and simultaneous screening of alpha1-adrenergic receptor antagonists in human plasma.
PubMed:Biodegradation of bis(2-chloroethyl) ether by Xanthobacter sp. strain ENV481.
PubMed:Study on hemostatic mechanism of fully soluble hemostatic fiber.
PubMed:Car-Parrinello and path integral molecular dynamics study of the hydrogen bond in the chloroacetic acid dimer system.
PubMed:Isolation and characterization of a novel haloacid permease from Burkholderia cepacia MBA4.
PubMed:An unusual toxic cause of hemolytic-uremic syndrome.
PubMed:Photochemical degradation of 1,3-dichloro-2-propanol aqueous solutions.
PubMed:Design and synthesis of some new thiazolo [3,2-b]-1,2,4-triazole-5(6H)-ones substituted with flurbiprofen as anti-inflammatory and analgesic agents.
PubMed:One-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones using chloroacetic acid as catalyst.
PubMed:meso-Aryl-substituted subporphyrins: synthesis, structures, and large substituent effects on their electronic properties.
PubMed:Proteomic analysis of Burkholderia cepacia MBA4 in the degradation of monochloroacetate.
PubMed:Methyl chloroacetate as an extraction solvent for coupling liquid-liquid semimicroextraction with micellar electrokinetic chromatography through on-capillary decomposition for the separation of neutral compounds with concentration enhancement.
PubMed:Variably elastic hydrogel patterned via capillary action in microchannels.
PubMed:1-(N-chloroacetylamino)-alkylphosphonic acids - synthetic precursors of phosphonopeptides.
PubMed:15N-labeled glycine synthesis.
PubMed:[Determination of trace haloacetic acids in drinking water using ion chromatography coupled with solid phase extraction].
PubMed:[Study advance on haloacetic acids in drinking water].
PubMed:Lethal acute lung injury and hypoglycemia after subcutaneous administration of monochloroacetic acid.
PubMed:On-line simultaneous removal of human serum albumin and enrichment of doxazosin using a weak cation-exchange monolithic column.
PubMed:Iatrogenic full-thickness chemical burns from monochloracetic acid.
PubMed:[Gas chromatography for determination of sodium monochloroacetate in biological samples].
PubMed:[Chemical burn].
PubMed:Photocatalytical degradation of 1,3-dichloro-2-propanol aqueous solutions by using an immobilized TiO2 photoreactor.
PubMed:Micronuclei induction and chromosomal aberrations in Rattus norvegicus by chloroacetic acid and chlorobenzene.
PubMed:Synthesis and biological evaluation of some pyrimidine, pyrimido[2,1-b][1,3]thiazine and thiazolo[3,2-a]pyrimidine derivatives.
PubMed:The role of structured water in the calibration and interpretation of theoretical IR spectra.
PubMed:Lack of effect on rat testicular organogenesis after in utero exposure to 3-monochloropropane-1,2-diol (3-MCPD).
PubMed:Application of a dialysis sampler to monitor phytoremediation processes.
PubMed:Treatment for simple plantar verrucae: monochloroacetic acid and 10% formaldehyde versus 10% formaldehyde alone.
PubMed:Relationship between chlorine consumption and chlorination by-products formation for model compounds.
PubMed:Adsorption kinetics of Cu(II) ions using N,O-carboxymethyl-chitosan.
PubMed:Geometry and cooperativity effects in adenosine-carboxylic acid complexes.
PubMed:Conductometric simultaneous determination of acetic acid, monochloroacetic acid and trichloroacetic acid using orthogonal signal correction-partial least squares.
PubMed:Natural formation and degradation of chloroacetic acids and volatile organochlorines in forest soil--challenges to understanding.
PubMed:Synthesis and reactions of some new substituted pyridine and pyrimidine derivatives as analgesic, anticonvulsant and antiparkinsonian agents.
PubMed:Validation of Haber's Rule (dose x time = constant) in rats and mice for monochloroacetic acid and 2,3,7,8-tetrachlorodibenzo-p-dioxin under conditions of kinetic steady state.
PubMed:Characterization of spontaneous and chemically induced cardiac lesions in rodent model systems: the national toxicology program experience.
PubMed:Animal glues in mixtures of natural binding media used in artistic and historic objects: identification by capillary zone electrophoresis.
PubMed:Biodegradation of monochloroacetic acid used as a sole carbon and energy source by Xanthobacter autotrophicus GJ10 strain in batch and continuous culture.
PubMed:Preparation of carboxymethyl chitosan in aqueous solution under microwave irradiation.
PubMed:Characterization of the metabolic interaction between trihalomethanes and chloroacetic acids using rat liver microsomes.
PubMed:Synthesis and tuberculostatic activity of some (4-phenylpiperazin-1-ylmethyl)-1,3,4-oxadiazole and (4-phenylpiperazin-1-ylmethyl)-1,2,4-triazole derivatives.
PubMed:Systemic effects and skin injury after experimental dermal exposure to monochloroacetic acid.
PubMed:Monochloroacetic acid inhibits liver gluconeogenesis by inactivating glyceraldehyde-3-phosphate dehydrogenase.
PubMed:Kinetics of haloacetic acid reactions with Fe(0).
PubMed:Synthesis and structural characterization of bioactive peptide conjugates using thioether linkage approaches.
PubMed:A family of Mn16 single-molecule magnets from a reductive aggregation route.
PubMed:Chemical and biological characterization of newly discovered iodoacid drinking water disinfection byproducts.
PubMed:Synthesis and evaluation of some novel quinazolinone derivatives as diuretic agents.
PubMed:Synthesis and properties of N-hexadecyl ethylenediamine triacetic acid.
PubMed:Genetic organization of the dhlA gene encoding 1,2-dichloroethane dechlorinase from Xanthobacter flavus UE15.
PubMed:Effects of superoxide dismutase and polyclonal tumor necrosis factor-alpha antibodies on chloroacetate-induced cellular death and superoxide anion production by J774.A1 macrophages.
PubMed:Batch-test study on the dechlorination of 1,1,1-trichloroethane in contaminated aquifer material by zero-valent iron.
PubMed:Stereoselective chloroacetate aldol reactions: syntheses of acetate aldol equivalents and darzens glycidic esters.
PubMed:Haloacetic acids in the aquatic environment. Part II: ecological risk assessment.
PubMed:Haloacetic acids in the aquatic environment. Part I: macrophyte toxicity.
PubMed:Therapeutic effects of glucose infusion on monochloroacetic acid exposure in rats.
PubMed:Identification of the major vanilloid component in Capsicum extract by HPLC-EC and HPLC-MS.
PubMed:Diastereoselective synthesis of cularine alkaloids via enium ions and an easy entry to isoquinolines by aza-Wittig electrocyclic ring closure.
PubMed:Change of monochloroacetic acid to biodegradable organic acids by hydrothermal reaction.
PubMed:[Study on a new antarthritic injection--O-carboxymethyl chitosan].
PubMed:Novel 3,3a,4,5,6,7-hexahydroindazole and arylthiazolylpyrazoline derivatives as anti-inflammatory agents.
PubMed:Evaluation of the influence of chloroacetic acids on the pharmacokinetics of trihalomethanes in the rat.
PubMed:An unusual cause of burn injury: skin exposure to monochloroacetic acid.
PubMed:[Occupational risk and evaluation of health damage in workers engaged in organochlorine compound production].
PubMed:Synthesis of some new benzothiazole derivatives as potential antimicrobial and antiparasitic agents.
PubMed:Kinetics of monochloroacetic acid at subtoxic and toxic doses in rats after single oral and dermal administrations.
PubMed:Horizontal transfer of dehalogenase genes on IncP1beta plasmids during bacterial adaptation to degrade alpha-halocarboxylic acids.
PubMed:Toxicological aspects of treatment to remove cyanobacterial toxins from drinking water determined using the heterozygous P53 transgenic mouse model.
PubMed:Incorporation of unprotected heterocyclic side chains into peptoid oligomers via solid-phase submonomer synthesis.
PubMed:Determination of chloroacetates in atmospheric particulate matter.
PubMed:Vacancy ion-exclusion chromatography of haloacetic acids on a weakly acidic cation-exchange resin.
PubMed:Formation of chloroacetic acids from soil, humic acid and phenolic moieties.
PubMed:Chloroacetic acids in European soils and vegetation.
PubMed:Synthesis of some new bis-thiazoles as possible anticancer agents.
PubMed:A facile preparation of 1-(6-hydroxyindol-1-yl)-2,2-dimethylpropan-1-one.
PubMed:Measurement of 13C/12C of chloroacetic acids by gas chromatography/combustion/isotope ratio mass spectrometry.
PubMed:Calpain mediates progressive plasma membrane permeability and proteolysis of cytoskeleton-associated paxillin, talin, and vinculin during renal cell death.
PubMed:Evaluation of monochloroacetic acid (MCA) degradation and toxicity to Lemna gibba, Myriophyllum spicatum, and Myriophyllum sibiricum in aquatic microcosms.
PubMed:Mammalian cell cytotoxicity and genotoxicity analysis of drinking water disinfection by-products.
PubMed:New technique for estimating thresholds of toxicity in ecological risk assessment.
PubMed:Cytoprotective properties of novel nonpeptide calpain inhibitors in renal cells.
PubMed:Synthesis and pharmacological activity of 1,4-benzodiazepine derivatives.
PubMed:Analysis of the cytotoxicity and mutagenicity of drinking water disinfection by-products in Salmonella typhimurium.
PubMed:Co-metabolic degradation of chlorinated hydrocarbons by Pseudomonas sp. strain DCA1.
PubMed:Resolution in capillary electrophoresis with nonaqueous methanol as solvent: theoretical prediction and experimental confirmation.
PubMed:Synthesis of some new quinoline derivatives: new routes to synthesize polysubstituted 2(1H)-quinolone derivatives.
PubMed:Chlorine kinetic isotope effect on the fluoroacetate dehalogenase reaction.
PubMed:Chemo-, regio-, and stereoselective cyclizations of 1,3-bis(trimethylsilyloxy)-1,3-butadienes with alpha-chloroacetic acid chlorides and alpha-chloroacetic acetals.
PubMed:The role of time as a quantifiable variable of toxicity and the experimental conditions when Haber's c x t product can be observed: implications for therapeutics.
PubMed:Kinetics of monochloroacetic acid in adult male rats after intravenous injection of a subtoxic and a toxic dose.
PubMed:Synthesis and analgesic activity of some novel 2-substituted 1,3,4-thiadiazolo
PubMed:The fate and persistence of trifluoroacetic and chloroacetic acids in pond waters.
PubMed:Synthesis of heterocyclic quinones containing bridgehead nitrogen atom from 2-aminonaphtho[2,3-d]thiazole-4,9-dione.
PubMed:Synthesis and antifungal activity of novel pyrano[2',3':4,5]thiazolo[2,3-b]quinazolines, pyrido[2',3':4,5]thiazolo[2,3-b]quinazolines and pyrazolo[2',3':4,5]thiazolo[2,3-b]quinazolines.
PubMed:The role of time in toxicology or Haber's c x t product.
PubMed:Sodium monochloroacetate causes cytotoxic effects, an increased lactate and pyruvate level and induces ultra structural and cytoskeletal alterations in cultured kidney and liver epithelial cells.
PubMed:Photodegradation of metolachlor: isolation, identification, and quantification of monochloroacetic acid.
PubMed:Determination of chloral hydrate metabolites in human plasma by gas chromatography-mass spectrometry.
PubMed:Synthesis and preliminary characterisation of charged derivatives and hydrogels from scleroglucan.
PubMed:Synthesis and evaluation of anti-inflammatory activity of some thiazolo[3,2-b]-1,2,4-triazole-5(6H)-ones and their Michael addition products.
PubMed:Synthesis and hypnotic activity of new 4-thiazolidinone and 2-thioxo-4,5-imidazolidinedione derivatives.
PubMed:Solid-phase microextraction coupled with gas chromatography-ion trap mass spectrometry for the analysis of haloacetic acids in water.
PubMed:Synthesis and anti-inflammatory activities of some thiazolo[3,2-a]pyrimidine derivatives.
PubMed:Preconcentration and separation of haloacetic acids by ion chromatography.
PubMed:Monooxygenase-mediated 1,2-dichloroethane degradation by Pseudomonas sp. strain DCA1.
PubMed:Interactive toxicity and stress protein expression by vinylidene chloride and monochloroacetate in precision-cut rat liver slices.
PubMed:Chloromethyl ketones are insulin-like stimulators of lipid synthesis in locust fat body.
PubMed:Reaction mechanism of fluoroacetate dehalogenase from Moraxella sp. B.
PubMed:Effect of dichloroacetic acid and trichloroacetic acid on DNA methylation in liver and tumors of female B6C3F1 mice.
PubMed:Cardiac teratogenicity of trichloroethylene metabolites.
PubMed:Species- and sex-related differences in metabolism of trichloroethylene to yield chloral and trichloroethanol in mouse, rat, and human liver microsomes.
PubMed:Capillary zone electrophoresis with indirect UV detection of haloacetic acids in water.
PubMed:Biochemical characterization of a haloalcohol dehalogenase from Arthrobacter erithii H10a.
PubMed:Synthesis and antimicrobial activity of pyridines bearing thiazoline and thiazolidinone moieties.
PubMed:Acute intoxication with trichloroethene: clinical symptoms, toxicokinetics, metabolism, and development of biochemical parameters for renal damage.
PubMed:[Synthesis and properties of 5(4,6-diphenyl-2-pyrimidin-2-yl)-1,2,4-triazolin-3-thione and derivatives ].
PubMed:Allergy to cocamidopropyl betaine may be due to amidoamine: a patch test and product use test study.
PubMed:Failure of monochloroacetic acid and trichloroacetic acid administered in the drinking water to produce liver cancer in male F344/N rats.
PubMed:Synthesis and antimicrobial screening of some novel thiazoles, dithiazoles and thiazolylpyridines.
PubMed:Comparative genotoxicity of halogenated acetic acids found in drinking water.
PubMed:Electrospray analysis of biological samples for trace amounts of trichloroacetic acid, dichloroacetic acid, and monochloroacetic acid.
PubMed:Reductive dehalogenation of halocarboxylic acids by the phototrophic genera Rhodospirillum and Rhodopseudomonas.
PubMed:A 13C NMR study of 2-(13)C-chloroacetaldehyde, a metabolite of ifosfamide and cyclophosphamide, in the isolated perfused rabbit heart model. Initial observations on its cardiotoxicity and cardiac metabolism.
PubMed:[Multi-elemental analysis by preconcentration on EDTA-cellulose microcolumn coupled to ICP-AES].
PubMed:Influence of hydroxypropyl beta-cyclodextrin on the stability of benzylpenicillin in chloroacetate buffer.
PubMed:Prevalence of monochloroacetate degrading genotypes among soil isolates of Pseudomonas sp.
PubMed:Comparisons on chemically-induced mutagenicity among four bacterial strains, Salmonella typhimurium TA102 and TA2638, and Escherichia coli WP2/pKM101 and WP2 uvrA/pKM101: collaborative study I.
PubMed:Tri-chloroacetic acid: a cause of vulvar vestibulitis.
PubMed:Synthesis and potent anti-HIV-1 activity of novel 6-benzyluracil analogues of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine.
PubMed:The Effect of Acid Strength on the Mitsunobu Esterification Reaction: Carboxyl vs Hydroxyl Reactivity.
PubMed:Metabolism of 1,2-dichloro-1-fluoroethane and 1-fluoro-1,2,2-trichloroethane: electronic factors govern the regioselectivity of cytochrome P450-dependent oxidation.
PubMed:A monoclonal antibody against a peptide sequence of fibrinogen gamma chain acts as an inhibitor of factor XIII-mediated crosslinking of human fibrin.
PubMed:Site Reactivity Probes: [1,2-13C]Chloroacetic Acid, A Reactivity Probe for Soil.
PubMed:Carboxymethylation of inulin.
PubMed:Accidental fatal monochloroacetic acid poisoning.
PubMed:Reaction of glutathione with the electrophilic metabolites of 1,1-dichloroethylene.
PubMed:Medium-chain acyl-CoA dehydrogenase- and enoyl-CoA hydratase-dependent bioactivation of 5,6-dichloro-4-thia-5-hexenoyl-CoA.
PubMed:Renal tumorigenicity of 1,1-dichloroethene in mice: the role of male-specific expression of cytochrome P450 2E1 in the renal bioactivation of 1,1-dichloroethene.
PubMed:Polysaccharides in Fungi. XXXIV. A polysaccharide from the fruiting bodies of Amanita muscaria and the antitumor activity of its carboxymethylated product.
PubMed:Simultaneous determination of lanthanum and cerium in mixed rare earths with p-acetylarsenazo by spectrophotometry.
PubMed:A simple method for screening assessment of skin and eye irritation.
PubMed:In vitro cytotoxicity of mono-, di-, and trichloroacetate and its modulation by hepatic peroxisome proliferation.
PubMed:Degradation of 2-chloroallylalcohol by a Pseudomonas sp.
PubMed:Reproductive risks from contaminants in drinking water.
PubMed:Synthesis of some new heterocyclic systems derived from 2-acetylbenzimidazole.
PubMed:Utilization of glutathione during 1,2-dihaloethane metabolism in rat hepatocytes.
PubMed:Sodium monochloroacetate poisoning of greenfinches.
PubMed:Aziridine-2-carboxylic acid. A reactive amino acid unit for a new class of cysteine proteinase inhibitors.
PubMed:Degradation of 1,2-dichloroethane by Ancylobacter aquaticus and other facultative methylotrophs.
PubMed:NTP Toxicology and Carcinogenesis Studies of Monochloroacetic Acid (CAS No. 79-11-8) in F344/N Rats and B6C3F1 Mice (Gavage Studies).
PubMed:Sex differences in monochloroacetate pretreatment effects on chloroform toxicity in rats.
PubMed:Tissue distribution of monochloroacetic acid and its binding to albumin in rats.
PubMed:Toxicity of monochloroacetic acid administered by gavage to F344 rats and B6C3F1 mice for up to 13 weeks.
PubMed:Fatal systemic poisoning after skin exposure to monochloroacetic acid.
PubMed:Analysis of DNA strand breaks induced in rodent liver in vivo, hepatocytes in primary culture, and a human cell line by chlorinated acetic acids and chlorinated acetaldehydes.
PubMed:Ninety day toxicity study of chloroacetic acids in rats.
PubMed:The acute effects of S-(1,2-dichlorovinyl)-L-cysteine and related chemicals on renal function and ultrastructure in the pentobarbital-anesthetized dog: structure-activity relationships, biotransformation, and unique site-specific nephrotoxicity.
PubMed:Metabolism of 14C-dichloroethyne in rats.
PubMed:Validated methods for degrading hazardous chemicals: some halogenated compounds.
PubMed:Ninety-day toxicity study of sodium monochloroacetate in Sprague-Dawley rats.
PubMed:Measurement of haloacetic acids and their decomposition in wine by capillary gas chromatography.
PubMed:Purification and characterization of haloalcohol dehalogenase from Arthrobacter sp. strain AD2.
PubMed:[A gas-chromatographic method of analysis of monochloroacetic acid and its sodium salt in the air, skin washings, protective clothing extracts and urine].
PubMed:Toxicokinetics of monochloroacetic acid: a whole-body autoradiography study.
PubMed:[Preparations of preoral sustained-release preparations with a biological polymer base. 5 (correct title supplied from Table of Contents)].
PubMed:Prediction of the developmental toxicity hazard potential of halogenated drinking water disinfection by-products tested by the in vitro hydra assay.
PubMed:[Effect of monoamine neurotransmitters in the hypothalamus in a cortisol-induced rat model of yang-deficiency].
PubMed:Intradural granulocytic sarcoma presenting as a lumbar radiculopathy. Case report.
PubMed:Ethylene dichloride: the influence of disulfiram or ethanol on oncogenicity, metabolism, and DNA covalent binding in rats.
PubMed:Monochloroacetic acid exposure: a case report.
PubMed:Species and strain sensitivity to the induction of peroxisome proliferation by chloroacetic acids.
PubMed:[Gas-chromatographic analysis of monochloracetic acid in the water].
PubMed:[Local and skin-resorptive effects of monochloracetic acid chloranhydride].
PubMed:Covalent interaction of chloroacetic and acetic acids with cholesterol.
PubMed:The changing role of ultraviolet spectroscopy in drug analysis.
PubMed:Gas chromatography/mass spectrometry study of mixed haloacetic acids expected to be found in chlorinated drinking water.
PubMed:Significance of fibrin/fibrinogen related antigen in glomeruli in children with IgA nephropathy.
PubMed:[Hygienic standardization of monochloracetic acid chloranhydride in the air of the work area].
PubMed:Intraglomerular deposition of fibrin/fibrinogen-related antigen in children with various renal diseases.
PubMed:Synthesis and pharmacological screening of some new triazoles.
PubMed:Indoxyl-beta-D-glucuronide, a novel chromogenic reagent for the specific detection and enumeration of Escherichia coli in environmental samples.
PubMed:Thioacylating intermediates as metabolites of S-(1,2-dichlorovinyl)-L-cysteine and S-(1,2,2-trichlorovinyl)-L-cysteine formed by cysteine conjugate beta-lyase.
PubMed:Monochloroacetic acid and 60% salicylic acid as a treatment for simple plantar warts: effectiveness and mode of action.
PubMed:Synthesis of regiospecifically labeled [18O]glycolic acid and [18O]acyldihydroxyacetone phosphate.
PubMed:Studies on aziridine derivatives. III. Synthesis and immunopharmacological activity of aziridine derivatives of propionic acid.
PubMed:Inter- and intramolecular deuterium isotope effects on the cytochrome P-450-catalyzed oxidative dehalogenation of 1,1,2,2-tetrachloroethane.
PubMed:Proton concentration jumps and generation of transmembrane pH-gradients by photolysis of 4-formyl-6-methoxy-3-nitrophenoxyacetic acid.
PubMed:Monochloroacetic acid toxicity in the mouse associated with blood-brain barrier damage.
PubMed:Determination of sodium monofluoroacetate (compound 1080) in tissues and baits as its benzyl ester by reaction-capillary gas chromatography.
PubMed:Cytogenetic studies on 1,1-dichloroethylene and its two isomers in mammalian cells in vitro and in vivo.
PubMed:The ethylester of monochloroacetic acid.
PubMed:Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay to coded chemicals. I: Results for nine compounds.
PubMed:Effect of chloroacetic acids on the kidneys.
PubMed:Contraluminal transport of small aliphatic carboxylates in the proximal tubule of the rat kidney in situ.
PubMed:Synthesis and antifertility activity of some new fluorine containing 2-([2-(fluoroaryl)-1H-indol-3- yl]methylene)hydrazinecarbothioamides and 2-(fluoroaryl)-([5-(substituted benzylidene)-4-oxo-2-thiazolidinylidene]hydrazone)- 1H-indole-3-carboxaldehydes.
PubMed:Synthesis of some indole derivatives with potential antiinflammatory activity.
PubMed:Sampling and analytical methods for the determination of monochloroacetic acid in air.
PubMed:Determination of 2-(4-isobutylphenyl)propionic acid in bulk drug and compressed tablets by reversed-phase high-performance liquid chromatography.
PubMed:Toxic effects of chlorinated and brominated alkanoic acids on Pseudomonas putida PP3: selection at high frequencies of mutations in genes encoding dehalogenases.
PubMed:[Metabolism of 1,2-dichloroethane in the human body in acute poisonings].
PubMed:Formation of glutathione conjugates by reactive metabolites of vinylidene chloride in microsomes and isolated hepatocytes.
PubMed:Uptake and metabolism of thyroid hormones by the rat foetus in early pregnancy.
PubMed:In vitro binding of acetic acid and its chlorinated derivatives by the soluble glutathione S-transferases from rat liver.
PubMed:Effect of phenoxy acids on rat liver regeneration.
PubMed:An acquired inhibitor of factor XIII with a qualitative abnormality of fibrin cross-linking.
PubMed:Incorporation of chlorinated alkanes into fatty acids of hydrocarbon-utilizing mycobacteria.
PubMed:Sodium monochloroacetate poisoning of cattle and sheep.
PubMed:2-Haloacid dehalogenase from a 4-chlorobenzoate-degrading Pseudomonas spec. CBS 3.
PubMed:N-acetylcysteine: its bioavailability and interaction with ifosfamide metabolites.
PubMed:Hepatic microsomal metabolism of the dichloroethanes.
PubMed:Preparation and characterization of acid dehydration products of aflatoxicol.
PubMed:Localization of intrarenal cross-linked fibrin in children with various renal diseases.
PubMed:[Electron microscopic study of the depolymerization process on unstabilized fibrin as affected by urea or monochloracetic acid].
PubMed:The 1,2-dichloroethylenes: their metabolism by hepatic cytochrome p-450 in vitro.
PubMed:[Artificial hypothermia in acute poisoning by 1,2-dichloroethane and its probable metabolites].
PubMed:Toxicokinetics of chloroethanol in the rat after single oral administration.
PubMed:Mutagenic evaluation of carcinogens and non-carcinogens in the L5178Y/TK assay utilizing postmitochondrial fractions (S9) from normal rat liver.
PubMed:Evidence for a close similarity in the catalytic sites of papain and ficin in near-neutral media despite differences in acidic and alkaline media. Kinetics of the reactions of papain and ficin with chloroacetate.
PubMed:N-chloroacetyl-[125I]iodotyramine: an alkylating agent with high specific activity.
PubMed:Effect of hydroxynitrobenzylation of tryptophan-177 on reactivity of active site cysteine-25 in papain.
PubMed:Acute topical exposure to a mixture of benzene, chloracetyl chloride and xylidine.
PubMed:Fibrin oligomers of high molecular weight soluble in MCA solutions: implications on the time course of fibrinI formation.
PubMed:Metabolism of three active analogues of the male antifertility agent alpha-chlorohydrin in the rat.
PubMed:Is the thiolate--imidazolium ion pair the catalytically important form of papain?
PubMed:Determination of small amounts of boron by radiation decomposition of chloroacetic acid solution.
PubMed:Affinity labeling of the catalytic subunit of cyclic AMP-dependent protein kinase by N alpha-tosyl-L-lysine chloromethyl ketone.
PubMed:Synthesis and chromatographic properties of Se-carboxymethyl-selenohomocysteamine (2-carboxymethyl, 3-aminopropyl selenide).
PubMed:[Investigation of LAP and alkaline phosphatase in the workers during the production of monochlor acetic acid (author's transl)].
PubMed:[Use of Bacillus megaterium H. in studying the antitumor properties of new ethyleneimine derivatives of N-dichlorophosphonyliminotri-chloroacetic acid trichlorophosphopolyalkane halides and chloroanhydridies].
PubMed:Differences in metabolism of vinylidene chloride between mice and rats.
PubMed:The biological fate of vinylidene chloride in rats.
PubMed:1,1-Dichloroethylene hepatotoxicity: proposed mechanism of action and distribution and binding of 14C radioactivity following inhalation exposure in rats.
PubMed:[Food additives and their possible genetic toxicity; microbiological determination].
PubMed:The mutagenicity of chloroethylene oxide, chloroacetaldehyde, 2-chloroethanol and chloroacetic acid, conceivable metabolites of vinyl chloride.
PubMed:The biological fate in rats of vinyl chloride in relation to its oncogenicity.
PubMed:Human, rat and mouse liver-mediated mutagenicity of vinyl chloride in S. typhimurium strains.
PubMed:Reaction of the sulfhydryl group of papain with chloroacetic acid.
PubMed:The rate-limiting reaction in papain action as derived from the reaction of the enzyme with chloroacetic acid.
PubMed:Properties of the single sulfhydryl group of streptococcal proteinase. A comparison of the rates of alkylation by chloroacetic acid and chloroacetamide.
PubMed:A case of skin contamination with carbon-14 labelled chloroacetic acid.
PubMed:[ON THE EFFECT OF CHLOROACETIC ACID ON BENZIMIDAZOLONE AND SOME OF ITS DERIVATIVES].
PubMed:[The chloroacetate of naphthol AS-D for the demonstration of the activity of the non-specific esterases in the leukocytes].
PubMed:Cation requirement for insolubility of fibrin in monochloroacetic acid.
PubMed:Esterase activity in leukocytes demonstrated by the use of naphthol AS-D chloroacetate substrate.
PubMed:[Findings on the mechanism of acid of iodo-, bromo- & chloracetic acid in the American cockroach].
PubMed:[Contact insecticidal power of chloracetic acid and certain of its esters for resistant flies].
PubMed:[Chemical resistance of certain materials in media containing chloroacetaldehyde, trichloroethane, hydrochloric acid, and chloroacetic acid].
PubMed:The actions of methylfluoroacetate on the papillary muscle of the cat with comparative experiments on the actions of methyl chloroacetate.
PubMed:[A case of peracute poisoning by monochloracetic acid].
PubMed:Synthesis of chloroacetic acid and glycine labeled with radioactive carbon in the carboxyl' group.
PubMed:The absence of effect of 2,4-dichlorophenoxyacetic acid (2,4-D) on certain fungi in culture.
PubMed:The antibacterial activity of monochloracetic acid.
PubMed:Effect of acetic, monochloracetic, dichloroacetic, and trichloroacetic acids on oxygen consumption of mouse liver.
 
Notes:
urinary metabolite of vinyl chloride. Prohibited from use in food Chloroacetic acid is the chemical compound with the formula ClCH2CO2H. This carboxylic acid is a useful building block in organic synthesis. Like other chloroacetic acids and related halocarbons, it is a potentially dangerous alkylating agent.
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