| PubMed:Thermosensitive liposomes with higher phase transition temperature for targeted drug delivery to tumor. |
| PubMed:Anticancer effects of brucine and gemcitabine combination in MCF-7 human breast cancer cells. |
| PubMed:Capillary Coated with Graphene Oxide as Stationary Phase for the Separation of Brucine and Strychnine by Capillary Electrophoresis. |
| PubMed:[Inducing-apoptosis effect of brucine on human monocytic leukemia cell line THP-1 and its mechanism]. |
| PubMed:[Brucine inhibits the proliferation of human lung cancer cell line PC-9 
via arresting cell cycle]. |
| PubMed:Ionic liquid-based electromembrane extraction and its comparison with traditional organic solvent based electromembrane extraction for the determination of strychnine and brucine in human urine. |
| PubMed:Brucine suppresses ethanol intake and preference in alcohol-preferring Fawn-Hooded rats. |
| PubMed:Functional activation of G-proteins coupled with muscarinic acetylcholine receptors in rat brain membranes. |
| PubMed:Theoretical investigations into spectral and non-linear optical properties of brucine and strychnine using density functional theory. |
| PubMed:Rapid separation and identification of Strychnos alkaloids metabolites in rats by ultra high performance liquid chromatography with linear ion trap Orbitrap mass spectrometry. |
| PubMed:Preparation of surface-imprinted polymer grafted with water-compatible external layer via RAFT precipitation polymerization for highly selective and sensitive electrochemical determination of brucine. |
| PubMed:Suppression of spectral anomalies in SSFP-NMR signal by the Krylov Basis Diagonalization Method. |
| PubMed:Pharmacological evaluation of total alkaloids from nux vomica: effect of reducing strychnine contents. |
| PubMed:Enantiopure o-ethyl phenylphosphonothioic Acid: a solvating agent for the determination of enantiomeric excesses. |
| PubMed:A study of Semen Strychni-induced renal injury and herb-herb interaction of Radix Glycyrrhizae extract and/or Rhizoma Ligustici extract on the comparative toxicokinetics of strychnine and brucine in rats. |
| PubMed:On-line two-step stacking in capillary zone electrophoresis for the preconcentration of strychnine and brucine. |
| PubMed:Metabolism of brucine: the important metabolic pathways of dihydroindole-type alkaloid for excretion in rats. |
| PubMed:Simultaneous detection of 22 toxic plant alkaloids (aconitum alkaloids, solanaceous tropane alkaloids, sophora alkaloids, strychnos alkaloids and colchicine) in human urine and herbal samples using liquid chromatography-tandem mass spectrometry. |
| PubMed:Development of nanoparticles-in-microparticles system for improved local retention after intra-articular injection. |
| PubMed:Carbon nanotubes reinforced hollow fiber solid phase microextraction for the determination of strychnine and brucine in urine. |
| PubMed:Hyaluronic acid-coated bovine serum albumin nanoparticles loaded with brucine as selective nanovectors for intra-articular injection. |
| PubMed:Anticarcinogenic effect of brucine in diethylnitrosamine initiated and phenobarbital-promoted hepatocarcinogenesis in rats. |
| PubMed:Brucine, an alkaloid from seeds of Strychnos nux-vomica Linn., represses hepatocellular carcinoma cell migration and metastasis: the role of hypoxia inducible factor 1 pathway. |
| PubMed:Brucine suppresses colon cancer cells growth via mediating KDR signalling pathway. |
| PubMed:[Optimization and application of method to determine plasma concentration of brucine]. |
| PubMed:HPLC-DAD method for comprehensive quality control of Semen Strychni. |
| PubMed:Dynamic detection of non-protein-bound strychnine and brucine in rabbit muscle and synovial fluid after topical application of total Strychnos alkaloid patches. |
| PubMed:Screening calmodulin-binding ligands using intensity-fading matrix-assisted laser desorption/ionization mass spectrometry. |
| PubMed:In vitro metabolism of brucine by human liver microsomes and its interactions with CYP substrates. |
| PubMed:Brucine, an effective natural compound derived from nux-vomica, induces G1 phase arrest and apoptosis in LoVo cells. |
| PubMed:Validated UPLC-MS/MS method for determination of moclobemide in human brain cell supernatant and its application to bidirectional transport study. |
| PubMed:Brucine-loaded liposomes composed of HSPC and DPPC at different ratios: in vitro and in vivo evaluation. |
| PubMed:Evaluation of the pharmacodynamics and pharmacokinetics of brucine following transdermal administration. |
| PubMed:Study of receptor mediated selective anion transmembrane transport using parallel artificial membrane permeability assay. |
| PubMed:Brucine, an indole alkaloid from Strychnos nux-vomica attenuates VEGF-induced angiogenesis via inhibiting VEGFR2 signaling pathway in vitro and in vivo. |
| PubMed:In vitro metabolism study of Strychnos alkaloids using high-performance liquid chromatography combined with hybrid ion trap/time-of-flight mass spectrometry. |
| PubMed:[Preparation and pharmacokinetics of brucine hydrogel patch]. |
| PubMed:Virtual screening of Indonesian herbal database as HIV-1 reverse transcriptase inhibitor. |
| PubMed:Effect of alkyl chain length of alcohols on cholesteric uniaxial to cholesteric biaxial phase transitions in a potassium laurate/alcohol/potassium sulfate/water/brucine lyotropic mixture: evidence of a first-order phase transition. |
| PubMed:Strychnos nux-vomica root extract induces apoptosis in the human multiple myeloma cell line-U266B1. |
| PubMed:[LC-MS/MS analysis of determination of strychnine and brucine in formaldehyde fixed tissue]. |
| PubMed:Brucine induces the apoptosis of U266 multiple myeloma cells by phosphorylation of c-Jun. |
| PubMed:In-vivo and In-vitro activities of medicinal plants on ecto, endo and haemoparasitic infections: a review. |
| PubMed:[Comparison on in vivo pharmacokinetics of brucine, total alkaloids of Strychni Semen and Strychni Semen pulveratum in rats]. |
| PubMed:Fixing latent fingermarks developed by iodine fuming: a new method. |
| PubMed:Rituals can kill - A fatal case of brucine poisoning. |
| PubMed:Simultaneous determination of six toxic alkaloids in human plasma and urine using capillary zone electrophoresis coupled to time-of-flight mass spectrometry. |
| PubMed:Development of brucine-loaded microsphere/thermally responsive hydrogel combination system for intra-articular administration. |
| PubMed:Improved pharmacokinetics and reduced toxicity of brucine after encapsulation into stealth liposomes: role of phosphatidylcholine. |
| PubMed:Effects of brucine on vascular endothelial growth factor expression and microvessel density in a nude mouse model of bone metastasis due to breast cancer. |
| PubMed:[Brucine chitosan thermosensitive hydrogel for intra-articular injection]. |
| PubMed:[Effect of NF-kappaB on inhibition of non-small cell lung cancer cell cyclooxygenase-2 by brucine]. |
| PubMed:Influence of P-glycoprotein on brucine transport at the in vitro blood-brain barrier. |
| PubMed:[Determination of brucine and strychnine in rat after cutaneous administration of semen strychni niosome gel by LC-MS/MS]. |
| PubMed:Strychnos nux-vomica seeds: Pharmacognostical standardization, extraction, and antidiabetic activity. |
| PubMed:Effects of brucine on bone metabolism in multiple myeloma. |
| PubMed:Simultaneous HPTLC determination of strychnine and brucine in strychnos nux-vomica seed. |
| PubMed:Effect of Shodhana (processing) on Kupeelu (Strychnos nux-vomica Linn.) with special reference to strychnine and brucine content. |
| PubMed:Safety of individual medication of Ma Qian Zi (semen strychni) based upon assessment of therapeutic effects of Guo's therapy against moderate fluorosis of bone. |
| PubMed:Simultaneous analysis of strychnine and brucine and their major metabolites by liquid chromatography-electrospray ion trap mass spectrometry. |
| PubMed:Anti-tumor effects of brucine immuno-nanoparticles on hepatocellular carcinoma. |
| PubMed:[Percutaneous permeability study for patches Shangshi Zhitong on different kinds of bases]. |
| PubMed:Effect of purificatory measures through cow's urine and milk on strychnine and brucine content of Kupeelu (Strychnos nuxvomica Linn.) seeds. |
| PubMed:The interaction of blood proteins with brucine. |
| PubMed:Analgesic and anti-inflammatory activity and pharmacokinetics of alkaloids from seeds of Strychnos nux-vomica after transdermal administration: effect of changes in alkaloid composition. |
| PubMed:Pharmacokinetics of brucine after intravenous and oral administration to rats. |
| PubMed:Ultra-performance liquid chromatography-tandem mass spectrometric method for the determination of strychnine and brucine in mice plasma. |
| PubMed:[Pharmacokinetics of brucine in rats after intravenous administration of liposomes containing total alkaloids from seed of Strychnos nux-vomica]. |
| PubMed:2,3-dimethoxy-10-oxostrychnidinium 2-(2,4,6-trinitroanilino)benzoate monohydrate: a 1:1 proton-transfer salt of brucine with o-picraminobenzoic acid. |
| PubMed:Effects of brucine combined with glycyrrhetinic acid or liquiritin on rat hepatic cytochrome P450 activities in vivo. |
| PubMed:Preparation, characterization and tissue distribution of brucine stealth liposomes with different lipid composition. |
| PubMed:A computational study on the role of chiral N-oxides in enantioselective Pauson-Khand reactions. |
| PubMed:[Effect of phospholipid composition on pharmaceutical properties and anti-tumor activity of stealth liposomes containing brucine]. |
| PubMed:[Apoptosis-inducing effects of brucine on human chronic myeloid leukemia cell line K562]. |
| PubMed:Study of pharmacokinetics and tissue distribution of liposomal brucine for dermal administration. |
| PubMed:Cytotoxic and antitumor effects of brucine on Ehrlich ascites tumor and human cancer cell line. |
| PubMed:A new method for the simultaneous analysis of strychnine and brucine in Strychnos nux-vomica unprocessed and processed seeds using a carbon-paste electrode modified with multi-walled carbon nanotubes. |
| PubMed:Inhibition of human Na(v)1.5 sodium channels by strychnine and its analogs. |
| PubMed:HPLC determination of strychnine and brucine in rat tissues and the distribution study of processed semen strychni. |
| PubMed:[Effect of brucine on secretion function and proliferation capability of T lymphocytes in patients with aplastic anemia]. |
| PubMed:[Effect of brucine on metabolism of osteoblasts and osteoclasts in multiple myeloma]. |
| PubMed:Fatal intoxication due to brucine. |
| PubMed:[Determination and comparison of plasma protein binding rate of alkaloids from seed of Strychnou nux-vomica]. |
| PubMed:Importance of media in shodhana (purification / processing) of poisonous herbal drugs. |
| PubMed:Simultaneous determination of six alkaloids in blood and urine using a hydrophilic interaction liquid chromatography method coupled with electrospray ionization tandem mass spectrometry. |
| PubMed:Spectroscopic and physicochemical studies on organic crystal of brucine hydrogen maleate pentahydrate. |
| PubMed:Modified porphyrin-brucine conjugated to gold nanoparticles and their application in photodynamic therapy. |
| PubMed:Brucine N-oxide-catalyzed Morita-Baylis-Hillman reaction of vinyl ketones: a mechanistic implication of dual catalyst system with proline. |
| PubMed:Prediction of functionally selective allosteric interactions at an M3 muscarinic acetylcholine receptor mutant using Saccharomyces cerevisiae. |
| PubMed:[A comparative study on HPLC fingerprint of Semen Strychni and the processed]. |
| PubMed:[Preparation and in vitro evaluation of brucine-loaded polylacticacid nanoparticles]. |
| PubMed:Brucine-derived amino alcohol catalyzed asymmetric Henry reaction: an orthogonal enantioselectivity approach. |
| PubMed:Death due to ingestion of nicotine-containing solution: case report and review of the literature. |
| PubMed:Preparative resolution of etodolac enantiomers by preferential crystallization method. |
| PubMed:Reversal of enantioselectivity between the copper(I)- and silver(I)-catalyzed 1,3-dipolar cycloaddition reactions using a brucine-derived amino alcohol ligand. |
| PubMed:A rare case of brucine poisoning complicated by rhabdomyolysis and acute renal failure. |
| PubMed:Ammonium sulfate gradient loading of brucine into liposomes: effect of phospholipid composition on entrapment efficiency and physicochemical properties in vitro. |
| PubMed:Rapid and sensitive determination of strychnine and brucine in human urine by capillary electrophoresis with field-amplified sample stacking. |
| PubMed:Absolute configuration of 3,3'-diphenyl-[2,2'-binaphthalene]-1,1'-diol revisited. |
| PubMed:A three-phase microfluidic chip for rapid sample clean-up of alkaloids from plant extracts. |
| PubMed:Preparation and pharmaceutical/pharmacodynamic evaluation of topical brucine-loaded liposomal hydrogel. |
| PubMed:Intestinal permeability of antitumor alkaloids from the processed seeds of Strychnos nux-vomica in a Caco-2 cell model. |
| PubMed:[Influencing factors in preparation of brucine liposomes by ammonium sulfate transmembrane gradients]. |
| PubMed:[Study on safety and pharmacodynamic action of transdermal liposomal brucine]. |
| PubMed:[Strychnos alkaloids inhibit the proliferation of adult rat neuroprogenitor cells]. |
| PubMed:[Pharmaceutical characteristics of brucine stealth liposomes]. |
| PubMed:Determination of strychnine and brucine in rat plasma using liquid chromatography electrospray ionization mass spectrometry. |
| PubMed:Anti-proliferative and cytotoxic effects of Strychnos nux-vomica root extract on human multiple myeloma cell line - RPMI 8226. |
| PubMed:Construction and evaluation of ion selective electrodes for nitrate with a summing operational amplifier. Application to tobacco analysis. |
| PubMed:Simultaneous determination of five toxic alkaloids in body fluids by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry. |
| PubMed:Final report of the safety assessment of Alcohol Denat., including SD Alcohol 3-A, SD Alcohol 30, SD Alcohol 39, SD Alcohol 39-B, SD Alcohol 39-C, SD Alcohol 40, SD Alcohol 40-B, and SD Alcohol 40-C, and the denaturants, Quassin, Brucine Sulfate/Brucine, and Denatonium Benzoate. |
| PubMed:[Study on transdermal absorption characteristics of brucine in vitro]. |
| PubMed:Simultaneous determination of thirteen plant alkaloids in a human specimen by SPE and HPLC. |
| PubMed:A simple method to identify the unprocessed Strychnos seeds used in herbal medicinal products. |
| PubMed:Development and validation of a TLC-densitometric method for the simultaneous quantitation of strychnine and brucine from Strychnos spp. and its formulations. |
| PubMed:Preparation of liposomal brucine and its pharmaceutical/pharmacodynamic characterization. |
| PubMed:Analysis of Strychnos alkaloids in traditional Chinese medicines with improved sensitivity by sweeping micellar electrokinetic chromatography. |
| PubMed:Pseudopolymorphism in brucine: brucine-water (1/2), the third crystal hydrate of brucine. |
| PubMed:Application of high performance capillary electrophoresis on toxic alkaloids analysis. |
| PubMed:Supramolecular tilt chirality in crystals of steroids and alkaloids. |
| PubMed:[Study on the interaction between brucine and bovine serum albumin]. |
| PubMed:[Paharmacological mechanisms of cellular immunity of overall alkali of tongbiling for the treatment of joint destruction]. |
| PubMed:The cytotoxicity induced by brucine from the seed of Strychnos nux-vomica proceeds via apoptosis and is mediated by cyclooxygenase 2 and caspase 3 in SMMC 7221 cells. |
| PubMed:Hollow fiber-based liquid-phase microextraction combined with on-line sweeping for trace analysis of Strychnos alkaloids in urine by micellar electrokinetic chromatography. |
| PubMed:The effect of nifedipine on oral contraceptive-induced hypertension in rats. |
| PubMed:Determinants of positive cooperativity between strychnine-like allosteric modulators and N-methylscopolamine at muscarinic receptors. |
| PubMed:Electrochemical study of brucine on an electrode modified with magnetic carbon-coated nickel nanoparticles. |
| PubMed:[Studies on quality control methods of nuxvomica]. |
| PubMed:Diffusion coefficient distribution from NMR-DOSY experiments using Hopfield neural network. |
| PubMed:Brucine salts of L-alpha-hydroxy acids: brucinium hydrogen (S)-malate pentahydrate and anhydrous brucinium hydrogen (2R,3R)-tartrate at 130 K. |
| PubMed:Interaction studies of multiple binding sites on m4 muscarinic acetylcholine receptors. |
| PubMed:Pharmacological characterisation of strychnine and brucine analogues at glycine and alpha7 nicotinic acetylcholine receptors. |
| PubMed:Two pseudopolymorphic hydrates of brucine: brucine-water (1/4) and brucine-water (1/5.25) at 130 K. |
| PubMed:Analysis of strychnos alkaloids using electrospray ionization Fourier transform ion cyclotron resonance multi-stage tandem mass spectrometry. |
| PubMed:The apoptotic effect of brucine from the seed of Strychnos nux-vomica on human hepatoma cells is mediated via Bcl-2 and Ca2+ involved mitochondrial pathway. |
| PubMed:The anti-tumor effects of alkaloids from the seeds of Strychnos nux-vomica on HepG2 cells and its possible mechanism. |
| PubMed:Identification of various allosteric interaction sites on M1 muscarinic receptor using 125I-Met35-oxidized muscarinic toxin 7. |
| PubMed:Separation and determination of strychnine and brucine in Strychnos nux-vomica L. and its preparation by nonaqueous capillary electrophoresis. |
| PubMed:Rapid separation of strychnine and brucine on a dynamically modified poly(dimethylsiloxane) microchip followed by electrochemical detection. |
| PubMed:Physicochemical characterization of the Strychnos alkaloids by capillary zone electrophoresis. |
| PubMed:Functional characterisation of human glycine receptors in a fluorescence-based high throughput screening assay. |
| PubMed:Neural representation of bitter taste in the nucleus of the solitary tract. |
| PubMed:Spectrophotometric determination of urinary iodine by the Sandell-Kolthoff reaction subsequent to dry alkaline ashing. Results from the Czech Republic in the period 1994-2002. |
| PubMed:[Concentration and determination of strychnine alkaloid in biological fluids]. |
| PubMed:Cyclic water pentamers in triclinic crystals of brucinium L-glycerate. |
| PubMed:New PVC nitrate-selective electrode: application to vegetables and mineral waters. |
| PubMed:Asparagine, valine, and threonine in the third extracellular loop of muscarinic receptor have essential roles in the positive cooperativity of strychnine-like allosteric modulators. |
| PubMed:Brucine and two solvates. |
| PubMed:Direct determination of brucine by square wave voltammetry on 4-amino-2-mercaptopyrimidine self-assembled monolayer gold electrode. |
| PubMed:Resolution of (+/-)-ibuprofen using (-)-brucine as a chiral selector by thin layer chromatography. |
| PubMed:Fluorescent pirenzepine derivatives as potential bitopic ligands of the human M1 muscarinic receptor. |
| PubMed:Metabolomic analysis of Strychnos nux-vomica, Strychnos icaja and Strychnos ignatii extracts by 1H nuclear magnetic resonance spectrometry and multivariate analysis techniques. |
| PubMed:Transverse dephasing optimised NMR spectroscopy in solids: natural-abundance 13C correlation spectra. |
| PubMed:Optimized and validated spectrophotometric methods for the determination of nicorandil in drug formulations and biological fluids. |
| PubMed:Analysis of strychnine from detoxified Strychnos nux-vomica [corrected] seeds using liquid chromatography-electrospray mass spectrometry. |
| PubMed:Inhibition of MAO A and B by some plant-derived alkaloids, phenols and anthraquinones. |
| PubMed:Functional characterisation of the human alpha1 glycine receptor in a fluorescence-based membrane potential assay. |
| PubMed:Analysis of strychnine and brucine in postmortem specimens by RP-HPLC: a case report of fatal intoxication. |
| PubMed:The indole alkaloids brucine, yohimbine, and hypaphorine are indole-3-acetic acid-specific competitors which do not alter auxin transport. |
| PubMed:On-chip potential gradient detection with a portable capillary electrophoresis system. |
| PubMed:Quantitative analysis of strychnine and Brucine in Strychnos nux-vomica using 1H-NMR. |
| PubMed:[Pharmacokinetics of the alkaloids from the processed seeds of Strychnos nux-vomica in rats]. |
| PubMed:Analgesic and anti-inflammatory properties of brucine and brucine N-oxide extracted from seeds of Strychnos nux-vomica. |
| PubMed:Highly sensitive reaction of nitrate with brucine and 3-methyl-2-benzothiazolinone hydrazone hydrochloride for the determination of nitrate in environmental samples. |
| PubMed:[HPLC determination of strychnine and brucine in Semen Strychni and its processed products]. |
| PubMed:Bisquaternary dimers of strychnine and brucine. A new class of potent enhancers of antagonist binding to muscarinic M2 receptors. |
| PubMed:Capillary electrophoresis with field-enhanced stacking for rapid and sensitive determination of strychnine and brucine. |
| PubMed:Comparison of the responses of the chorda tympani and glossopharyngeal nerves to taste stimuli in C57BL/6J mice. |
| PubMed:[Determination of brucine in seed dressing agents by high performance liquid chromatography]. |
| PubMed:First synthesis of racemic saphenamycin and its enantiomers. investigation of biological activity. |
| PubMed:[Increased level of nitric oxide stable metabolites in the blood of highlanders]. |
| PubMed:Analogs of WIN 62,577 define a second allosteric site on muscarinic receptors. |
| PubMed:Herbal medicine causing likely strychnine poisoning. |
| PubMed:Atypical time course of clinical signs in a dog poisoned by strychnine. |
| PubMed:Enantiopure spiro[3.3]heptane-2,6-dicarboxylic acid. |
| PubMed:Asymmetric carbon-carbon coupling of phenols or anilines with aryllead triacetates. |
| PubMed:Enzymatic and non-enzymatic reduction of brucine N-oxide by aldehyde oxidase and catalase. |
| PubMed:[Influence of processing methods on alkaloid, toxicity and effect of Strychnos nux-vomica L]. |
| PubMed:[Determation of strychnine and brucine in Strychnos by HPLC]. |
| PubMed:A novel generation of coupling reagents. Enantiodifferentiating coupling reagents prepared in situ from 2-chloro-4,6-dimethoxy-1,3,5-triazine (CDMT) and chiral tertiary amines. |
| PubMed:Interactions between allosteric modulators and 4-DAMP and other antagonists at muscarinic receptors: potential significance of the distance between the N and carboxyl C atoms in the molecules of antagonists. |
| PubMed:Multiple allosteric sites on muscarinic receptors. |
| PubMed:Nitric oxide and chronic HCV and HIV infections. |
| PubMed:Non-enzymatic reduction of aliphatic tertiary amine N-oxides mediated by the haem moiety of cytochrome P450. |
| PubMed:A new chiral selector based on trans-acenaphthen-1,2-dicarboxylic acid. |
| PubMed:Separation and determination of strychnine and brucine in Strychnos nux-vomica L. and its preparation by capillary zone electrophoresis. |
| PubMed:Snake toxins with high selectivity for subtypes of muscarinic acetylcholine receptors. |
| PubMed:Effects of brucine, a plant alkaloid, on M(1) muscarinic receptors and alpha(1)-adrenoceptors in the rabbit vas deferens preparation. |
| PubMed:Allosteric interactions of staurosporine and other indolocarbazoles with N-[methyl-(3)H]scopolamine and acetylcholine at muscarinic receptor subtypes: identification of a second allosteric site. |
| PubMed:Determination of the alkaloid content in different parts of some Mahonia plants by HPCE. |
| PubMed:Direct enantiomeric resolution of some 2-arylpropionic acids using (-)-brucine-impregnated thin-layer chromatography. |
| PubMed:Cytotoxicities of alkaloids from processed and unprocessed seeds of Strychnos nux-vomica. |
| PubMed:Effect of brucine on mouse nonspecific immune responses. |
| PubMed:Subtype-selective positive cooperative interactions between brucine analogs and acetylcholine at muscarinic receptors: functional studies. |
| PubMed:Allosteric effects of four stereoisomers of a fused indole ring system with 3H-N-methylscopolamine and acetylcholine at M1-M4 muscarinic receptors. |
| PubMed:Allosteric interactions of quaternary strychnine and brucine derivatives with muscarinic acetylcholine receptors. |
| PubMed:A unique tertiary amine N-oxide reduction system composed of quinone reductase and heme in rat liver preparations. |
| PubMed:Quinone-dependent tertiary amine N-oxide reduction in rat blood. |
| PubMed:The effects of brucine and alcuronium on the inhibition of [3H]acetylcholine release from rat striatum by muscarinic receptor agonists. |
| PubMed:Subtype-selective positive cooperative interactions between brucine analogues and acetylcholine at muscarinic receptors: radioligand binding studies. |
| PubMed:Membrane potential responses of paramecium caudatum to bitter substances: existence of multiple pathways for bitter responses |
| PubMed:Behavioral specificity of the bitter taste gene Soa. |
| PubMed:Nonenzymatic reduction of brucine N-oxide by the heme group of cytochrome P450. |
| PubMed:Positive cooperativity of acetylcholine and other agonists with allosteric ligands on muscarinic acetylcholine receptors. |
| PubMed:[Chemical constituents of Strychnos nitida G. Don]. |
| PubMed:Age-related changes of urinary nitrite/nitrate excretion in normal children. |
| PubMed:Selective allosteric enhancement of the binding and actions of acetylcholine at muscarinic receptor subtypes. |
| PubMed:Spectrophotometric determination of urinary iodine by flow-injection analysis with on-line catalytic digestion. |
| PubMed:SW.B6-Soa(b) nontaster congenic strains completed and a sucrose octaacetate congenic quartet tested with other bitters. |
| PubMed:Brucine as a potent inducer of CYP2B3, the third member of the CYP2B subfamily P450 in rats. |
| PubMed:Effects of chronic treatment with losartan on blood pressure, endothelin-like immunoreactivity and nitric oxide in normotensive rats. |
| PubMed:Indirect measurement of brucine by adsorptive stripping voltammetry at mercury electrode. |
| PubMed:Determination of strychnine and brucine by capillary zone electrophoresis. |
| PubMed:On identifying a second molecular antagonistic mechanism operative at the glycine receptor. |
| PubMed:Quinine-HCl-induced modification of receptor potentials for taste stimuli in frog taste cells. |
| PubMed:[Influence of different processing methods of four alkaloid contents in Strychnos nux-vomica L]. |
| PubMed:Genetics of bitter perception in mice. |
| PubMed:Strychnine-binding proteins in intestinal cells: novel brucine binding site with binding affinities for alkaloids. |
| PubMed:Novel and potent aldose reductase inhibitors: 4-benzyl- and 4-(benzothiazol-2-ylmethyl)-3,4-dihydro-3-oxo-2H-1,4-benzothiazine-2-ac etic acid derivatives. |
| PubMed:[Effect of processing on the alkaloids in Strychnos nux-vomica L]. |
| PubMed:Strychnine and brucine as the potent inducers of drug metabolizing enzymes in rat liver: different profiles from phenobarbital on the induction of cytochrome P450 and UDP-glucuronosyltransferase. |
| PubMed:A putative cytoprotective receptor in the kidney: relation to the neuronal strychnine-sensitive glycine receptor. |
| PubMed:[Studies on the chemical constituents of alkaloids in seeds of Strychnos nux-vomica L]. |
| PubMed:Metabolism of strychnine N-oxide and brucine N-oxide by human intestinal bacteria. |
| PubMed:[Effect of processing on the extraction of alkaloids from Strychnos]. |
| PubMed:[An attempt to investigate the effect of magnesium ion supplements on changes in levels of nitrates and nitrites in selected pickled vegetables]. |
| PubMed:Comparison of binding at strychnine-sensitive (inhibitory glycine receptor) and strychnine-insensitive (N-methyl-D-aspartate receptor) glycine binding sites. |
| PubMed:Strychnine-induced potassium current in CA1 pyramidal neurones of the rat hippocampus. |
| PubMed:Synthesis and aromatase inhibition of 3-cycloalkyl-substituted 3-(4-aminophenyl)piperidine-2,6-diones. |
| PubMed:Brucine lethality in mice. |
| PubMed:[Effect of the fermentation process on levels of nitrates and nitrites in selected vegetables]. |
| PubMed:[Simultaneous determination of brucine and strychnine in semen Strychni by dual wavelength spectrophotometry and studies on processing principles of semen Strychni]. |
| PubMed:[Quantitative determination of strychnine and brucine in semen Strychni and its preparations by gas chromatography]. |
| PubMed:Processing of nux vomica. II. Changes in alkaloid composition of the seeds of Strychnos nux-vomica on traditional drug-processing. |
| PubMed:[Combinations of borotungstic acid with nitrogenous compounds]. |
| PubMed:Photosynthetic control, "energy-dependent" quenching of chlorophyll fluorescence and photophosphorylation under influence of tertiary amines. |
| PubMed:Glassy state of pharmaceuticals. IV. Studies on glassy pharmaceuticals by thermomechanical analysis. |
| PubMed:[Studies on the relation of alkaloids in semen Strychni and its processing]. |
| PubMed:A re-examination of the Na+-independent binding of [3H]beta-alanine to rat brain stem-spinal cord. |
| PubMed:Thermodynamic evaluation of activated charcoal as a poison antidote by high-performance liquid chromatography. II: In vitro method for the evaluation of activated charcoal as a poison antidote. |
| PubMed:Effect of inferior olive lesion on seizure threshold in the rat. |
| PubMed:Protein ligand interactions. Indole alkaloids as inhibitors for lactate dehydrogenase. |
| PubMed:A recombinagenic effect of strychnine in Salmonella typhimurium. |
| PubMed:Glycine antagonists structurally related to 4,5,6,7-tetrahydroisoxazolo [5,4-c]pyridin-3-ol inhibit binding of [3H]strychnine to rat brain membranes. |
| PubMed:Iontophoretic studies on rat hippocampus with some novel GABA antagonists. |
| PubMed:Droplet counter-current chromatography of alkaloids. The influence of ph-gradients and ion-pair formation on the retention of alkaloids. |
| PubMed:Tlc - spectrophotometric analysis of strychnine and brucine from the ayurvedic pills of nux vomica. |
| PubMed:[Quality control of galenic preparations of nux vomica: proposal for a new method of extracting and assaying strychnine and brucine]. |
| PubMed:Cardiac stimulation of brucine in cockroach Periplaneta americana, L. |
| PubMed:First derivative spectrophotometric determination of strychnine and brucine in nux vomica liquid extract. |
| PubMed:Toxic alkaloids and their interaction with microsomal cytochrome P-450 in vitro. |
| PubMed:A new high performance liquid chromatography (HPLC) method for the quantitation of strychnine in urine and tissue extracts. |
| PubMed:The adaptation of the frog tongue to various taste solutions: the effect on gustatory neural responses to bitter stimuli. |
| PubMed:13C-NMR experimental methods for determination of resonance multiplicities: Strychnos alkaloids. |
| PubMed:Assignment of 13C-NMR spectra of strychnine and brucine. |
| PubMed:An experimental model of hyper-irritability in the trigeminal skin field of the rat. |
| PubMed:13C-NMR spectra of strychnos alkaloids: brucine and strychnine. |
| PubMed:Absolute configuration of (+)-5-(o-hydroxyphenyl)-5-phenylhydantoin, the major metabolite of 5,5-diphenylhydantoin in the dog. |
| PubMed:Spectrophotometric determination of strychnine and brucine in liquid galenicals. |
| PubMed:Potential carcinostatics. Synthesis and biological properties of d- and 1-beta,beta-difluoroaspartic acid and beta,beta-difluoroasparagine. |
| PubMed:Studies of antitumor agents. 1. Resolution of racemic 1-(tetrahydro-2-furanyl)-k-fluorouracil into the R and S isomers and examination of the biological activities of the isomers. |
| PubMed:Observations on the reaction between nitric acid and brucine. |
| PubMed:The alkaloids of Strychnos dolichothyrsa. |
| PubMed:A relatively simple differential screening test for GABA or glycine antagonists using rat electroretinography. |
| PubMed:Mechanism of action of some bitter-tasting compounds on frog taste cells. |
| PubMed:Formation of beta-methylmalate and its conversion to citramalate in Rhodospirillum rubrum. |
| PubMed:Simultaneous assay for six alkaloids in opium, using high-performance liquid chromatography. |
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| PubMed:Redox indicators in titrations in aqueous nitric acid. |
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| PubMed:METABOLISM OF DRUGS. 48. THE STUDY OF SELECTIVE DEMETHYLATION OF BRUCINE IN VIVO. |
| PubMed:METABOLISM OF DRUGS. L. THE IN VITRO STUDY ON METABOLISM OF BRUCINE AND 4-SUBSTITUTED VERATROLES. |
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| PubMed:[THIN-LAYER CHROMATOGRAPHY WITHOUT A BINDING AGENT IN DRUG ANALYSIS. 6. RADIOMETRIC DETERMINATION OF STRYCHNINE AND BRUCINE IN GALENICAL PREPARATIONS]. |
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| PubMed:The Differential Action of Brucine and of Strychnine. |
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