laureth-23
poly(oxy-1,2-ethanediyl), .alpha.-dodecyl-.omega.-hydroxy- (23 mol EO average molar ratio)

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  CODE122542 CODE122542
  Product(s):
  MP-023976 LAURETH 23
  MP-024569 LAURETH-23 FLAKES
  MP-030286 LAURETH-23 SCHUPPEN MB (MASS BALANCE)

Name: 2-dodecoxyethanol (peg-23) CAS Number: 9002-92-0 3D/inchi Other(deleted CASRN): 101008-55-3 ECHA ELINCS - REACH Pre-Reg: 500-002-6 FDA UNII: J89TKQ5R54 Nikkaji Web: J92.963H Beilstein Number: 1748129 XlogP3: 5.10 (est) Formula: (C2 H4 O)mult-C12 H26 O NMR Predictor: Predict (works with chrome, Edge or firefox) Category:emulsifiers, surfactants   US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information: Google Scholar: Search Google Books: Search Google Scholar: with word "volatile" Search Google Scholar: with word "flavor" Search Google Scholar: with word "odor" Search Google Patents: Search US Patents: Search EU Patents: Search Pubchem Patents: Search PubMed: Search NCBI: Search   Physical Properties: Assay: 95.00 to 100.00 Food Chemicals Codex Listed: No Boiling Point: 304.00 to 305.00 °C. @ 760.00 mm Hg (est) Flash Point: > 220.00 °F. TCC ( > 104.44 °C. ) logP (o/w): 4.909 (est)   Organoleptic Properties: Odor Strength:none Odor Description:at 100.00 %. bland Odor and/or flavor descriptions from others (if found).   Cosmetic Information: CosIng: cosmetic data Cosmetic Uses: cleansing agents surfactants surfactant - emulsifying   Suppliers: Croda Brij™ L23 Odor: bland Use: Easy-to-handle pastillated form; solubiliser and dispersant. ECSA Chemicals LAURETH 23 ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY ECSA Chemicals LAURETH-23 FLAKES ECSA Chemicals LAURETH-23 SCHUPPEN MB (MASS BALANCE) Kao Corporation EMULGEN 123P Odor: characteristic Use: Emulsifier for cosmetics and pharmaceuticals Lipo Chemicals Lipocol® L-23 Odor: characteristic Use: Lipocol® L-23 is used as a cleansing agent and solubilizer in acne scrubs, medicated shampoos, scalp treatment products and bubble baths. It is a primary component of emulsifier systems for antiperspirants, depilatories and cleansing creams and lotions. It is an efficient perfume solubilizer for shampoo and liquid detergents.   Safety Information:   Hazards identification   Classification of the substance or mixture GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) None found. GHS Label elements, including precautionary statements   Pictogram   Hazard statement(s) None found. Precautionary statement(s) None found. Oral/Parenteral Toxicity: intravenous-guinea pig LD50 38 mg/kg BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) KIDNEY, URETER, AND BLADDER: HEMATURIA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Arzneimittel-Forschung. Drug Research. Vol. 7, Pg. 162, 1957. oral-guinea pig LD50 384 mg/kg PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Arzneimittel-Forschung. Drug Research. Vol. 7, Pg. 162, 1957. intraperitoneal-mouse LD50 160 mg/kg Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 967, 1991. intraperitoneal-mouse LD50 160 mg/kg Drugs in Japan Vol. -, Pg. 1300, 1995. intravenous-mouse LD50 100 mg/kg Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 967, 1991. intravenous-mouse LD50 100 mg/kg Toxicology and Applied Pharmacology. Vol. 7, Pg. 206, 1965. oral-mouse LD50 1170 mg/kg Toxicology and Applied Pharmacology. Vol. 2, Pg. 133, 1960. oral-mouse LD50 1170 mg/kg PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Arzneimittel-Forschung. Drug Research. Vol. 7, Pg. 162, 1957. oral-mouse LD50 3500 mg/kg American Perfumer and Cosmetics. Vol. 77, Pg. 35, 1962. oral-mouse LD50 4940 mg/kg American Perfumer and Cosmetics. Vol. 77, Pg. 35, 1962. intratracheal-rabbit LD50 > 15 mg/kg Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 78, 1976. intravenous-rabbit LD50 36 mg/kg KIDNEY, URETER, AND BLADDER: HEMATURIA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) Arzneimittel-Forschung. Drug Research. Vol. 7, Pg. 162, 1957. parenteral-rabbit LD50 > 75 mg/kg Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 78, 1976. intraperitoneal-rat LD50 125 mg/kg GASTROINTESTINAL: OTHER CHANGES Food and Cosmetics Toxicology. Vol. 8, Pg. 125, 1970. intravenous-rat LD50 27 mg/kg Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 967, 1991. intravenous-rat LD50 27 mg/kg Drugs in Japan Vol. -, Pg. 1300, 1995. intravenous-rat LD50 390 mg/kg Toxicology and Applied Pharmacology. Vol. 2, Pg. 133, 1960. oral-rat LD50 1000 mg/kg LIVER: FATTY LIVER DEGERATION GASTROINTESTINAL: OTHER CHANGES GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH Food and Cosmetics Toxicology. Vol. 8, Pg. 125, 1970. oral-rat LD50 4150 mg/kg Toxicology and Applied Pharmacology. Vol. 2, Pg. 133, 1960. oral-rat LD50 8600 mg/kg Soap, Perfumery & Cosmetics. Vol. 38, Pg. 47, 1965. Dermal Toxicity: subcutaneous-mouse LD50 792 mg/kg Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 967, 1991. subcutaneous-mouse LD50 792300 ug/kg Drugs in Japan Vol. -, Pg. 1300, 1995. subcutaneous-rat LD50 953 mg/kg Drugs in Japan Vol. -, Pg. 1300, 1995. subcutaneous-rat LD50 954 mg/kg Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 967, 1991. Inhalation Toxicity: Not determined   Safety in Use Information: Category: emulsifiers, surfactants Recommendation for laureth-23 usage levels up to:   not for fragrance use.   Recommendation for laureth-23 flavor usage levels up to:   not for flavor use.   Safety References: EPI System: View ClinicalTrials.gov:search Chemical Carcinogenesis Research Information System:Search AIDS Citations:Search Cancer Citations:Search Toxicology Citations:Search EPA Substance Registry Services (TSCA):9002-92-0 EPA ACToR:Toxicology Data EPA Substance Registry Services (SRS):Registry Laboratory Chemical Safety Summary :24750 National Institute of Allergy and Infectious Diseases:Data WGK Germany:2 2-dodecoxyethanol (peg-23) Chemidplus:0009002920 EPA/NOAA CAMEO:hazardous materials   References:   2-dodecoxyethanol (peg-23) NIST Chemistry WebBook: Search Inchi Canada Domestic Sub. List: 9002-92-0 Pubchem (cid): 24750 Pubchem (sid): 135050657   Other Information: (IUPAC): Atomic Weights of the Elements 2011 (pdf) Videos: The Periodic Table of Videos tgsc: Atomic Weights use for this web site (IUPAC): Periodic Table of the Elements CHEBI: View CHEMBL: View KEGG (GenomeNet): D01539 HMDB (The Human Metabolome Database): Search ChemSpider: View Formulations/Preparations: grades or purity: usually 100%   Potential Blenders and core components note None Found   Potential Uses: None Found   Occurrence (nature, food, other):note   not found in nature   Synonyms:   ameroxol LE-23   brij 23   brij 35P   brij L23   brij L23-25   britex L 230   chemal LA 23 2- dodecoxyethanol (peg-23)   emulgen 123P   ethosperse LA 23   lipocol L-23   macol LA-23   peg-23 lauryl ether   poly(oxy-1,2-ethanediyl), .alpha.-dodecyl-.omega.-hydroxy- (23 mol EO average molar ratio)   polyethylene glycol (23) lauryl ether   polyethylene glycol (23) monolauryl ether   polyoxyethylene (23) lauryl ether   polyoxyethylene (23) monolauryl ether   simulsol P 23   volpo L 23   Articles:   None found yet. Try the PubMed Search.

Notes: polyethylene glycol monododecyl ether (average polymer n=9).