(E)-para-hydroxycinnamic acid, 501-98-4

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CODE120378 CODE120378
Product(s):
501-98-4 trans-4-Hydroxycinnamic acid 0.98
trans-4-Hydroxycinnamic acid isolated from the herb of Trifolium pratense. It has anti-bacteria effect against some gram-positive and gram-negative bacteria. antibacterial; antimicrobial;

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CODE120378 CODE120378
Product(s):
GK1602 4-Hydroxycinnamic acid

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CODE120378 CODE120378
Product(s):
08-58600 TRANS-P-HYDROXYCINNAMIC ACID

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CODE120378 CODE120378
Product(s):
C0393 trans-p-Coumaric Acid >98.0%(GC)(T)
SDS

Name:	(E)-3-(4-hydroxyphenyl)prop-2-enoic acid
CAS Number:	501-98-4	3D/inchi
FDA UNII:	IBS9D1EU3J
Nikkaji Web:	J6.196D
Beilstein Number:	2207381
MDL:	MFCD00004399
XlogP3:	1.50 (est)
Molecular Weight:	164.16036000
Formula:	C9 H8 O3
BioActivity Summary:	listing
NMR Predictor:	Predict (works with chrome, Edge or firefox)

Category:natural substances and extractives

US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:

Google Scholar:	Search
Google Books:	Search
Google Scholar: with word "volatile"	Search
Google Scholar: with word "flavor"	Search
Google Scholar: with word "odor"	Search
Google Patents:	Search
US Patents:	Search
EU Patents:	Search
Pubchem Patents:	Search
PubMed:	Search
NCBI:	Search

Physical Properties:

Assay:	95.00 to 100.00
Food Chemicals Codex Listed:	No
Melting Point:	214.00 °C. @ 760.00 mm Hg
Boiling Point:	346.00 to 347.00 °C. @ 760.00 mm Hg (est)
Flash Point:	351.00 °F. TCC ( 177.30 °C. ) (est)
logP (o/w):	1.460
Soluble in:
	alcohol
	water, 1.83e+004 mg/L @ 25 °C (est)

Organoleptic Properties:

Odor Description:at 100.00 %. balsamic

Odor and/or flavor descriptions from others (if found).

Cosmetic Information:

None found

Suppliers:

Alfa Biotechnology

For experimental / research use only.

p-Coumaric acid 98%

BOC Sciences

For experimental / research use only.

trans-4-Hydroxycinnamic acid 0.98

Odor: characteristic

Use: trans-4-Hydroxycinnamic acid isolated from the herb of Trifolium pratense. It has anti-bacteria effect against some gram-positive and gram-negative bacteria. antibacterial; antimicrobial;

Glentham Life Sciences

4-Hydroxycinnamic acid

Penta International

TRANS-P-HYDROXYCINNAMIC ACID

Santa Cruz Biotechnology

For experimental / research use only.

p-Coumaric acid ≥99%

Sigma-Aldrich: Sigma

For experimental / research use only.

p-Coumaric acid ≥98.0% (HPLC)

sds

TCI AMERICA

For experimental / research use only.

trans-p-Coumaric Acid >98.0%(GC)(T)

sds

Safety Information:

Preferred SDS: View

Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-mouse LD50 2850 mg/kg BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION Gendai no Rinsho. Vol. 3, Pg. 675, 1969. intraperitoneal-mouse LD50 1160 mg/kg BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION Gendai no Rinsho. Vol. 3, Pg. 675, 1969.
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in Use Information:

Category:
natural substances and extractives
Recommendation for (E)-para-hydroxycinnamic acid usage levels up to:
	not for fragrance use.

Recommendation for (E)-para-hydroxycinnamic acid flavor usage levels up to:
	not for flavor use.

Safety References:

EPI System: View

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :637542

National Institute of Allergy and Infectious Diseases:Data

WGK Germany:2

(E)-3-(4-hydroxyphenyl)prop-2-enoic acid

Chemidplus:0000501984

RTECS:GD9095000 for cas# 501-98-4

References:

	(E)-3-(4-hydroxyphenyl)prop-2-enoic acid
NIST Chemistry WebBook:	Search Inchi
Pubchem (cid):	637542
Pubchem (sid):	134978583
Flavornet:	501-98-4

Other Information:

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
CHEBI:	View
CHEMBL:	View
Golm Metabolome Database:	Search
KEGG (GenomeNet):	C00811
HMDB (The Human Metabolome Database):	HMDB02035
FooDB:	FDB002594
YMDB (Yeast Metabolome Database):	YMDB00498
Export Tariff Code:	2918.29.2000
VCF-Online:	VCF Volatile Compounds in Food
ChemSpider:	View

Potential Blenders and core components note

None Found

Potential Uses:

None Found

Occurrence (nature, food, other):note

	alfalfa Search Trop Picture
	apple plant Search Trop Picture
	artichoke jerusalem artichoke Search Trop Picture
	cherry black cherry Search Trop Picture
	clover red clover Search Trop Picture
	coffee Search PMC Picture
	coriander fruit Search Trop Picture
	coriander plant Search Trop Picture
	coriander seed Search Trop Picture
	cynomorium songaricum Search Trop Picture
	orange fruit juice Search Trop Picture
	pea Search Trop Picture
	sage Search Trop Picture
	wasabi Search Trop Picture

Synonyms:

	cinnamic acid, p-hydroxy-, (E)-
(E)-p-	coumaric acid
(E)-para-	coumaric acid
trans-4-	coumaric acid
trans-p-	coumaric acid
trans-para-	coumaric acid
(E)-p-	coumarinic acid
(E)-para-	coumarinic acid
trans-p-	coumarinic acid
trans-para-	coumarinic acid
(E)-3-(4-	hydroxy-phenyl)-acrylic acid
(E)-4-	hydroxycinnamic acid
(E)-p-	hydroxycinnamic acid
trans-4-	hydroxycinnamic acid
trans-p-	hydroxycinnamic acid
trans-para-	hydroxycinnamic acid
4-	hydroxycinnamic acid (predominantly trans)
(E)-3-(4-	hydroxyphenyl)-2-propenoic acid
(2E)-3-(4-	hydroxyphenyl)acrylic acid
(2E)-3-(4-	hydroxyphenyl)acryls�ure
(2E)-3-(4-	hydroxyphenyl)prop-2-enoic acid
(E)-3-(4-	hydroxyphenyl)prop-2-enoic acid
(E)-	naringeninic acid
2-	propenoic acid, 3-(4-hydroxyphenyl)-, (2E)-
2-	propenoic acid, 3-(4-hydroxyphenyl)-, (E)- (9CI)

Articles:

PubMed:Granatumins A-G, limonoids from the seeds of a Krishna mangrove, Xylocarpus granatum.

PubMed:Toxicity of cassia and cinnamon oil compounds and cinnamaldehyde-related compounds to Sitophilus oryzae (Coleoptera: Curculionidae).

PubMed:Induction of 4-hydroxycinnamate decarboxylase in Klebsiella oxytoca cells exposed to substrates and non-substrate 4-hydroxycinnamate analogs.

PubMed:Stereochemically specific proton transfer in decarboxylation of 4-hydroxycinnamic acids by 4-hydroxycinnamate decarboxylase from Klebsiella oxytoca.

PubMed:Trans/cis (Z/E) photoisomerization of the chromophore of photoactive yellow protein is not a prerequisite for the initiation of the photocycle of this photoreceptor protein.

Notes:

isolated from cynomorium songaricum Widespread in plants, e.g. peel of black cherry (Prunus serotina), lentil seeds and from red clover (Trifolium pratense). Found by Bate-Smith in 48% of investigated dicotyledonous and 55% of monocotyledonous spp. Coumaric acid is a hydroxycinnamic acid, an organic compound that is a hydroxy derivative of cinnamic acid. There are three isomers, o-coumaric acid, m-coumaric acid, and p-coumaric acid, that differ by the position of the hydroxy substitution of the phenyl group. p-Coumaric acid is the most abundant isomer of the three in nature. (Wikipedia)

(E)-para-hydroxycinnamic acid 2-propenoic acid, 3-(4-hydroxyphenyl)-, (E)- (9CI)

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Articles:

(E)-para-hydroxycinnamic acid
2-propenoic acid, 3-(4-hydroxyphenyl)-, (E)- (9CI)