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4-hydroxypropiophenone
1-propanone, 1-(4-hydroxyphenyl)-

Supplier Sponsors

Name:1-(4-hydroxyphenyl)propan-1-one
CAS Number: 70-70-2Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:200-743-2
FDA UNII: X9952001TG
Nikkaji Web:J4.879H
Beilstein Number:0907511
MDL:MFCD00002361
XlogP3:2.00 (est)
Molecular Weight:150.17710000
Formula:C9 H10 O2
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:information only not used for fragrances or flavors
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
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Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Appearance:white to tan crystalline powder (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 148.00 to 151.00 °C. @ 760.00 mm Hg
Boiling Point: 299.00 to 300.00 °C. @ 760.00 mm Hg (est)
Vapor Pressure:0.001000 mmHg @ 25.00 °C. (est)
Flash Point: 259.00 °F. TCC ( 126.20 °C. ) (est)
logP (o/w): 2.030
Soluble in:
 water, 345 mg/L @ 15 °C (exp)
 
Organoleptic Properties:
Flavor Type: phenolic
phenolic
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
1-(4-Hydroxyphenyl)propan-1-one >98%
Odor: characteristic
Use: Paroxypropione is a natural phenylpropanoid found in the herbs of Cedrus deodara. Paroxypropione has been found to possess antioxidant and antioxidant activities. antigonadotropin, antioxidant
EMD Millipore
For experimental / research use only.
4'-Hydroxypropiophenone
Penta International
P-HYDROXY PROPIOPHENONE
Santa Cruz Biotechnology
For experimental / research use only.
4'-Hydroxypropiophenone
Sigma-Aldrich: Aldrich
For experimental / research use only.
4'-Hydroxypropiophenone 98%
TCI AMERICA
For experimental / research use only.
4'-Hydroxypropiophenone >98.0%(GC)
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-mouse LD50 200 mg/kg
National Technical Information Service. Vol. AD277-689

parenteral-frog LD50 91 mg/kg
PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 124, Pg. 212, 1960.

oral-rat LD > 500 mg/kg
National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. Vol. 5, Pg. 29, 1953.

Dermal Toxicity:
subcutaneous-mouse LD50 1.13 mg/kg
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 124, Pg. 212, 1960.

subcutaneous-mouse LD50 1130 ug/kg
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 124, Pg. 212, 1960.

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
information only not used for fragrances or flavors
Recommendation for 4-hydroxypropiophenone usage levels up to:
 not for fragrance use.
 
Recommendation for 4-hydroxypropiophenone flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):70-70-2
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :6271
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
1-(4-hydroxyphenyl)propan-1-one
Chemidplus:0000070702
RTECS:UH1925000 for cas# 70-70-2
 
References:
 1-(4-hydroxyphenyl)propan-1-one
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):6271
Pubchem (sid):134972132
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C13342
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2914.50.3000
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 ethyl p-hydroxyphenyl ketone
 ethyl para-hydroxyphenyl ketone
1-(4-hydroxy-phenyl)-propan-1-one
p-hydroxyl propiophenone
p-hydroxyphenyl-1-propanone
1-(4-hydroxyphenyl)-1-propanone
1-(p-hydroxyphenyl)-1-propanone
1-(4-hydroxyphenyl)propan-1-one
4'-hydroxypropiophenone
p-hydroxypropiophenone
 hypophenon
 ibiopopp
 paraoxypropiophenone
 paroxypropion
 paroxypropione
1-propanone, 1-(4-hydroxyphenyl)-
4-propionylphenol
p-propionylphenol
p-propiophenol
 propiophenone, 4'-hydroxy-
 proxiphenon
 sterofenon
 
 
Notes:
None found
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