EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

3-hydroxyflavone
4H-1-benzopyran-4-one, 3-hydroxy-2-phenyl-

Supplier Sponsors

CAS Number: 577-85-5Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:209-416-9
FDA UNII: ZTG9LSS5QH
Nikkaji Web:J630.345E
MDL:MFCD00006832
XlogP3:3.40 (est)
Molecular Weight:238.24230000
Formula:C15 H10 O3
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:information only not used for fragrances or flavors
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
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Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 171.00 °C. @ 760.00 mm Hg
Boiling Point: 393.72 °C. @ 760.00 mm Hg (est)
Vapor Pressure:2.750000 mmHg @ 25.00 °C. (est)
Flash Point: 305.00 °F. TCC ( 151.50 °C. ) (est)
logP (o/w): 3.477 (est)
Soluble in:
 water, 158.1 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Alfa Biotechnology
For experimental / research use only.
3-Hydroxyflavone 98%
BOC Sciences
For experimental / research use only.
3-Hydroxyflavone
ExtraSynthese
For experimental / research use only.
3-Hydroxyflavone (HPLC) ≥95%
Penta International
3-HYDROXY FLAVONE
Santa Cruz Biotechnology
For experimental / research use only.
3-Hydroxyflavone ≥98%
Sigma-Aldrich: Aldrich
For experimental / research use only.
3-Hydroxyflavone ≥98%
TCI AMERICA
For experimental / research use only.
3-Hydroxyflavone >98.0%(HPLC)(T)
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intravenous-mouse LD50 56 mg/kg
U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#02588

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
information only not used for fragrances or flavors
Recommendation for 3-hydroxyflavone usage levels up to:
 not for fragrance use.
 
Recommendation for 3-hydroxyflavone flavor usage levels up to:
 not for flavor use.
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Scientific Report of EFSA on the risk assessment of salts of authorised acids, phenols or alcohols for use in food contact materials [1]
View page or View pdf

EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):577-85-5
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :11349
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
3-hydroxy-2-phenylchromen-4-one
Chemidplus:0000577855
RTECS:LK8650000 for cas# 577-85-5
 
References:
 3-hydroxy-2-phenylchromen-4-one
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:577-85-5
Pubchem (cid):11349
Pubchem (sid):134977063
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
Golm Metabolome Database:Search
KEGG (GenomeNet):C01495
HMDB (The Human Metabolome Database):HMDB31816
FooDB:FDB008491
Export Tariff Code:2932.99.7000
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 fenugreek fruit
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 fenugreek seed
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 papaya leaf
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 pomegranate fruit
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 raspberry red raspberry fruit juice
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 tea leaf
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Synonyms:
4H-1-benzopyran-4-one, 3-hydroxy-2-phenyl-
 flavon-3-ol
 flavone, 3-hydroxy-
3-hydroxy-2-phenyl-4H-1-benzopyran-4-one
3-hydroxy-2-phenyl-4H-chromen-4-one
3-hydroxy-2-phenylchromen-4-one
3-hydroxy-2-phenylchromone
 

Articles:

PubMed:Behavior of the potential antitumor V(IV)O complexes formed by flavonoid ligands. 1. Coordination modes and geometry in solution and at the physiological pH.
PubMed:Excited-State Dynamics of 3-Hydroxyflavone Anion in Alcohols.
PubMed:Monitoring penetratin interactions with lipid membranes and cell internalization using a new hydration-sensitive fluorescent probe.
PubMed:Excited state chemistry of flavone derivatives in a confined medium: ESIPT emission in aqueous media.
PubMed:Structure, solvation, and dynamics of Mg²⁺, Ca²⁺, Sr²⁺, and Ba²⁺ complexes with 3-hydroxyflavone and perchlorate anion in acetonitrile medium: a molecular dynamics simulation study.
PubMed:Proton transfer reactions of 4'-chloro substituted 3-hydroxyflavone in solvents and aqueous micelle solutions.
PubMed:Differences in the hydroxylation pattern of flavonoids alter their chemoprotective effect against direct- and indirect-acting mutagens.
PubMed:Characterization of the structural modifications accompanying the loss of HBsAg particle immunogenicity.
PubMed:Analysis of flavonoids regulating the expression of UGT1A1 via xenobiotic receptors in intestinal epithelial cells.
PubMed:Hexanoyl-lysine as an oxidative-injured marker - application of development of functional food.
PubMed:Effects of 3-hydroxyflavone on the cellular and molecular characteristics of bovine embryos produced by somatic-cell nuclear transfer.
PubMed:Antimicrobial and antioxidant effects of spice extracts on the shelf life extension of raw chicken meat.
PubMed:Dual-fluorescence L-amino acid reports insertion and orientation of melittin peptide in cell membranes.
PubMed:Accurate determination of the orientational distribution of a fluorescent molecule in a phospholipid membrane.
PubMed:A new minor homoisoflavonoid from Caesalpinia sappan.
PubMed:Reaction-based and single fluorescent emitter decorated ratiometric nanoprobe to detect hydrogen peroxide.
PubMed:Monitoring membrane properties and apoptosis using membrane probes of the 3-hydroxyflavone family.
PubMed:Evaluation of estrogenic potential of flavonoids using a recombinant yeast strain and MCF7/BUS cell proliferation assay.
PubMed:Excitation wavelength dependence of excited state intramolecular proton transfer reaction of 4'-N,N-diethylamino-3-hydroxyflavone in room temperature ionic liquids studied by optical Kerr gate fluorescence measurement.
PubMed:Transcriptomic analysis of UV-treated rice leaves reveals UV-induced phytoalexin biosynthetic pathways and their regulatory networks in rice.
PubMed:Design and exploratory data analysis of a second generation of dendrimer prodrugs potentially antichagasic and leishmanicide.
PubMed:Probing 3-hydroxyflavone for in vitro glycorandomization of flavonols by YjiC.
PubMed:Validated LC-MS/MS method for the determination of 3-hydroxflavone and its glucuronide in blood and bioequivalent buffers: application to pharmacokinetic, absorption, and metabolism studies.
PubMed:Hydroxyflavones as a new family of matrices for MALDI tissue imaging.
PubMed:Eupatilin, a major flavonoid of Artemisia, attenuates aortic smooth muscle cell proliferation and migration by inhibiting PI3K, MKK3/6, and MKK4 activities.
PubMed:Mechanism of the antihypertensive and vasorelaxant effects of the flavonoid tiliroside in resistance arteries.
PubMed:Delivering flavonoids into solid tumors using nanotechnologies.
PubMed:A flavonoid 8-C-glycoside and a triterpenoid cinnamate from Nervilia fordii.
PubMed:Indirect activation of the SV23 and SV24 splice variants of human constitutive androstane receptor: analysis with 3-hydroxyflavone and its analogues.
PubMed:Mutual regioselective inhibition of human UGT1A1-mediated glucuronidation of four flavonoids.
PubMed:Fluorescence behavior of (selected) flavonols: a combined experimental and computational study.
PubMed:Ab initio study on an excited-state intramolecular proton-transfer reaction in ionic liquid.
PubMed:Evaluation of antioxidant efficacy of vanadium-3-hydroxyflavone complex in streptozotocin-diabetic rats.
PubMed:A comparative photochemical study on the behavior of 3,3'-dihydroxyflavone and its complex with La(III) as generators and quenchers of reactive oxygen species.
PubMed:Five new flavonoid glycosides from Nervilia fordii.
PubMed:Comparison of inhibition capability of scutellarein and scutellarin towards important liver UDP-glucuronosyltransferase (UGT) isoforms.
PubMed:Identification and characterization of a novel kaempferol sulfotransferase from Arabidopsis thaliana.
PubMed:Anomalous ground-state proton transfer of 4'-N,N-diethylamino-3-hydroxyflavone in ionic liquids of imidazolium-based cations with tetrafluoroborate.
PubMed:A genetic and metabolic analysis revealed that cotton fiber cell development was retarded by flavonoid naringenin.
PubMed:Carbon nano-onions and biocompatible polymers for flavonoid incorporation.
PubMed:Natural compounds with cell growth inhibitory activity in human tumor cell lines.
PubMed:Interaction of antitumor flavonoids with dsDNA in the absence and presence of Cu(II).
PubMed:Utilizing modified flavonoids to construct a chemodosimeter array for discrimination of different palladium species by using principal component analysis.
PubMed:Boron difluoride complexes of 3-hydroxyflavone derivatives: efficient bioinspired dyes for solution and solid-state emission.
PubMed:3-Hydroxyflavones vs. 3-hydroxyquinolinones: structure-activity relationships and stability studies on Ru(II)(arene) anticancer complexes with biologically active ligands.
PubMed:Influences of glucose on the dietary hydroxyflavonoid-plasma protein interaction.
PubMed:Antioxidant and cytotoxic activities of Sideritis perezlarae (Borja) Roselló, Stübing and Peris.
PubMed:Transient IR spectroscopy and ab initio calculations on ESIPT in 3-hydroxyflavone solvated in acetonitrile.
PubMed:Selective fluorometric detection of pyrophosphate by 3-hydroxyflavone-diphenyltin(IV) complex in aqueous micellar medium.
PubMed:Combined treatment of 3-hydroxyflavone and imatinib mesylate increases apoptotic cell death of imatinib mesylate-resistant leukemia cells.
PubMed:Prevention of cisplatin ototoxicity: Efficacy of micronized flavonoid fraction in a guinea pig model.
PubMed:Comparison of health-relevant flavonoids in commonly consumed cranberry products.
PubMed:The structure of HBsAg particles is not modified upon their adsorption on aluminium hydroxide gel.
PubMed:Ab initio study of the solvent H-bonding effect on ESIPT reaction and electronic transitions of 3-hydroxychromone derivatives.
PubMed:Molecular dynamics of excited state intramolecular proton transfer: 3-hydroxyflavone in solution.
PubMed:Structural and spectroscopic study of Al(III)-3-hydroxyflavone complex: determination of the stability constants in water-methanol mixtures.
PubMed:Mutagenicity of flavonoids assayed by bacterial reverse mutation (Ames) test.
PubMed:The basic antioxidant structure for flavonoid derivatives.
PubMed:Infrared/ultraviolet quadruple resonance spectroscopy to investigate structures of electronically excited states.
PubMed:Facile syntheses of 3-hydroxyflavones.
PubMed:Quantification of local hydration at the surface of biomolecules using dual-fluorescence labels.
PubMed:Integration of organic fluorophores in the surface of polymer-coated colloidal nanoparticles for sensing the local polarity of the environment.
PubMed:Design, synthesis and characterization of zinc-3 hydroxy flavone, a novel zinc metallo complex for the treatment of experimental diabetes in rats.
PubMed:Novel metal based anti-tuberculosis agent: synthesis, characterization, catalytic and pharmacological activities of copper complexes.
PubMed:Novel copper-based therapeutic agent for anti-inflammatory: synthesis, characterization, and biochemical activities of copper(II) complexes of hydroxyflavone Schiff bases.
PubMed:Spectroscopic exploration of mode of binding of ctDNA with 3-hydroxyflavone: a contrast to the mode of binding with flavonoids having additional hydroxyl groups.
PubMed:Molecular modeling study on the disassembly of dendrimers designed as potential antichagasic and antileishmanial prodrugs.
PubMed:Fluorescence light-up recognition of DNA nucleotide based on selective abasic site binding of an excited-state intramolecular proton transfer probe.
PubMed:A systems approach to identifying correlated gene targets for the loss of colour pigmentation in plants.
PubMed:Effects of micronised purified flavonoid fraction on pain, semen analysis and scrotal color Doppler parameters in patients with painful varicocele; results of a randomized placebo-controlled study.
PubMed:3-Hydroxyflavone improves the in vitro development of cloned porcine embryos by inhibiting ROS production.
PubMed:Electronic spectroscopy of molecules in superfluid helium nanodroplets: an excellent sensor for intramolecular charge redistribution.
PubMed:Transparent nanometric organic luminescent films as UV-active components in photonic structures.
PubMed:Probing the interactions of hemoglobin with antioxidant flavonoids via fluorescence spectroscopy and molecular modeling studies.
PubMed:Effect of 3-hydroxyflavone on pig embryos produced by parthenogenesis or somatic cell nuclear transfer.
PubMed:[Research on antiproliferative effect of flavones isolated from Laggera pterodonta].
PubMed:Recent experimental advances on excited-state intramolecular proton coupled electron transfer reaction.
PubMed:Monitoring membrane binding and insertion of peptides by two-color fluorescent label.
PubMed:[Effect of seven kinds of flavonoids on recombinant human protein tyrosine phosphatase].
PubMed:Effects of multibranching on 3-hydroxyflavone-based chromophores and the excited-state intramolecular proton transfer dynamics.
PubMed:Excited state intramolecular proton transfer reaction of 4'-N,N-diethylamino-3-hydroxyflavone and solvation dynamics in room temperature ionic liquids studied by optical Kerr gate fluorescence measurement.
PubMed:Conformation and intermolecular interactions of SA2 peptides self-assembled into vesicles.
PubMed:Biomimetic photocycloaddition of 3-hydroxyflavones: synthesis and evaluation of rocaglate derivatives as inhibitors of eukaryotic translation.
PubMed:Effect of selected flavones on cancer and endothelial cells.
PubMed:Microbial glucosylation of flavonols by Cunninghamella echinulata.
PubMed:Characterization of the lipid and protein organization in HBsAg viral particles by steady-state and time-resolved fluorescence spectroscopy.
PubMed:Identifying apoptotic cells with the 3-hydroxyflavone derivative F2N12S, a ratiometric fluorescent small molecule probe selective for plasma membranes: a possible general mechanism for selective uptake into apoptotic cells.
PubMed:A comparative study of flavonoid analogues on streptozotocin-nicotinamide induced diabetic rats: quercetin as a potential antidiabetic agent acting via 11beta-hydroxysteroid dehydrogenase type 1 inhibition.
PubMed:Polarity assessment of thermoresponsive poly(NIPAM-co-NtBA) copolymer films using fluorescence methods.
PubMed:Liquid ordered phase in cell membranes evidenced by a hydration-sensitive probe: effects of cholesterol depletion and apoptosis.
PubMed:Proton transfer reactions in nanoscopic polar domains: 3-hydroxyflavone in AOT reverse micelles.
PubMed:Fluorescence lifetime tuning--a novel approach to study flip-flop kinetics in supported phospholipid bilayers.
PubMed:Photochemistry of 3-hydroxyflavone inside superfluid helium nanodroplets.
PubMed:Unusually slow proton transfer dynamics of a 3-hydroxychromone dye in protic solvents.
PubMed:Photophysical behaviour of ground state anion and phototautomer of 3-hydroxyflavone in liposome membrane.
PubMed:Excited state intramolecular proton transfer in 3-hydroxy flavone and 5-hydroxy flavone: a DFT based comparative study.
PubMed:[Spectroscopic investigation of 3-hydroxyflavone in different polarity and pH values solutions].
PubMed:A triple-emission fluorescent probe reveals distinctive amyloid fibrillar polymorphism of wild-type alpha-synuclein and its familial Parkinson's disease mutants.
PubMed:3-Hydroxyflavone inhibits endogenous Aurora B and induces growth inhibition of cancer cell line.
PubMed:Flavonoid-induced morphological modifications of endothelial cells through microtubule stabilization.
PubMed:Acidity of hydroxyl groups: an overlooked influence on antiradical properties of flavonoids.
PubMed:IR spectroscopy applied subsequent to a proton transfer reaction in the excited state of isolated 3-hydroxyflavone and 2-(2-naphthyl)-3-hydroxychromone.
PubMed:Multiparametric probing of microenvironment with solvatochromic fluorescent dyes.
PubMed:Total synthesis of the potent anticancer Aglaia metabolites (-)-silvestrol and (-)-episilvestrol and the active analogue (-)-4'-desmethoxyepisilvestrol.
PubMed:IR/UV spectroscopy on jet cooled 3-hydroxyflavone (H2O)n (n = 1,2) clusters along proton transfer coordinates in the electronic ground and excited states.
PubMed:Visualization of lipid domains in giant unilamellar vesicles using an environment-sensitive membrane probe based on 3-hydroxyflavone.
PubMed:Excited state proton transfer and solvent relaxation of a 3-hydroxyflavone probe in lipid bilayers.
PubMed:Ground- and excited-state proton transfer and antioxidant activity of 3-hydroxyflavone in egg yolk phosphatidylcholine liposomes: absorption and fluorescence spectroscopic studies.
PubMed:Liquid ordered and gel phases of lipid bilayers: fluorescent probes reveal close fluidity but different hydration.
PubMed:Photochemistry of metal complexes of 3-hydroxyflavone: towards a better understanding of the influence of solar light on the metal-soil organic matter interactions.
PubMed:Iron-binding properties of plant phenolics and cranberry's bio-effects.
PubMed:Sensing of adenosine-5'-triphosphate anion in aqueous solutions and mitochondria by a fluorescent 3-hydroxyflavone dye.
PubMed:Fragmentation of 3-hydroxyflavone; a computational and mass spectrometric study.
PubMed:IGF-I plus E2 induces proliferation via activation of ROS-dependent ERKs and JNKs in human breast carcinoma cells.
PubMed:N,N'-dimethylformamide-derived products from catalytic oxidation of 3-hydroxyflavone.
PubMed:Identification of yellow dye types in pre-columbian andean textiles.
PubMed:Fluorescent biomembrane probe for ratiometric detection of apoptosis.
PubMed:Evaluation of novel chromogenic substrates for the detection of bacterial beta-glucosidase.
PubMed:Interaction of flavonoids with red blood cell membrane lipids and proteins: antioxidant and antihemolytic effects.
PubMed:Fluorescent dyes undergoing intramolecular proton transfer with improved sensitivity to surface charge in lipid bilayers.
PubMed:Dramatic pressure-dependent quenching effects in supercritical CO2 assessed by the fluorescence of 4'-dimethylamino-3-hydroxyflavone. Thermodynamic versus kinetics control of excited-state intramolecular proton transfer.
PubMed:A self-organized ensemble of fluorescent 3-hydroxyflavone-Al (III) complex as sensor for fluoride and acetate ions.
PubMed:Spectroscopic and theoretical studies of the Zn(II) chelation with hydroxyflavones.
PubMed:A highly selective spectrophotometric determination of niobium (V) using 3-hydroxy-2-[1'-phenyl-3'-(p-chlorophenyl)-4'-pyrazolyl]-4-oxo-4H-1-benzopyran as a complexing agent.
PubMed:Time dependent density functional theory study of electronic absorption properties of lead(II) complexes with a series of hydroxyflavones.
PubMed:Femtosecond dynamics on excited-state proton/charge-transfer reaction in 4'-N,N-diethylamino-3-hydroxyflavone. The role of dipolar vectors in constructing a rational mechanism.
PubMed:Synthesis and immunosuppressive activity of L-rhamnopyranosyl flavonoids.
PubMed:Antitrypanosomal and antileishmanial activities of flavonoids and their analogues: in vitro, in vivo, structure-activity relationship, and quantitative structure-activity relationship studies.
PubMed:Microbial metabolism. Part 6. Metabolites of 3- and 7-hydroxyflavones.
PubMed:Fluorescent hydroxyflavone-zeolite nanoparticles: ship-in-a-bottle synthesis and photophysical properties.
PubMed:The effects of thermal quenching on the excited-state intramolecular proton transfer reaction in 3-hydroxyflavones.
PubMed:Fluorometric detection of adenosine triphosphate with 3-hydroxy-4'-(dimethylamino)flavone in aqueous solutions.
PubMed:Membrane dipole potential as measured by ratiometric 3-hydroxyflavone fluorescence probes: accounting for hydration effects.
PubMed:Spectroscopy and femtosecond dynamics of 7-N,N-diethylamino-3-hydroxyflavone. The correlation of dipole moments among various states to rationalize the excited-state proton transfer reaction.
PubMed:A triterpene oleanolic acid conjugate with 3-hydroxyflavone derivative as a new membrane probe with two-color ratiometric response.
PubMed:Phytoestrogens as inhibitors of fungal 17beta-hydroxysteroid dehydrogenase.
PubMed:Phytoestrogens as inhibitors of fungal 17beta-hydroxysteroid dehydrogenase.
PubMed:Two-color fluorescent probes for imaging the dipole potential of cell plasma membranes.
PubMed:Heat perturbation of bovine eye lens alpha-crystallin probed by covalently attached ratiometric fluorescent dye 4'-diethylamino-3-hydroxyflavone.
PubMed:Stability of ferric complexes with 3-hydroxyflavone (flavonol), 5,7-dihydroxyflavone (chrysin), and 3',4'-dihydroxyflavone.
PubMed:[IR and Raman spectroscopic studies on the complexes of ytterbium with pyran derivatives].
PubMed:Dipole moments of 4'-aminoflavonol fluorescent probes in different solvents.
PubMed:Cytotoxicity of flavonoids toward cultured normal human cells.
PubMed:Glucosylation of phenolic compounds by Pharbitis nil hairy roots: I. Glucosylation of coumarin and flavone derivatives.
PubMed:A biomimetic approach to the rocaglamides employing photogeneration of oxidopyryliums derived from 3-hydroxyflavones.
PubMed:Simultaneous probing of hydration and polarity of lipid bilayers with 3-hydroxyflavone fluorescent dyes.
PubMed:Ground- and excited-state proton transfer reaction of 3-hydroxyflavone in dimyristoylphosphatidylcholine liposome membrane.
PubMed:Anti-HIV and cytotoxic ruthenium(II) complexes containing flavones: biochemical evaluation in mice.
PubMed:Two new 5-deoxyflavonoids from Calliandra inermis.
PubMed:In vitro flavon-3-ol oxidation mediated by a B ring hydroxylation pattern.
PubMed:Resolution of Cys and Lys labeling of alpha-crystallin with site-sensitive fluorescent 3-hydroxyflavone dye.
PubMed:Bimodal distribution and fluorescence response of environment-sensitive probes in lipid bilayers.
PubMed:Comparative photodegradation studies on 3-hydroxyflavone: influence of different media, pH and light sources.
PubMed:Effects of alpha- and beta-cyclodextrin complexation on the physico-chemical properties and antioxidant activity of some 3-hydroxyflavones.
PubMed:Selective reversed-phase liquid chromatography method for the kinetic investigation of 3-hydroxyflavone photostability.
PubMed:3-OH flavone inhibition of epidermal growth factor-induced proliferaton through blocking prostaglandin E2 production.
PubMed:Ultrasensitive two-color fluorescence probes for dipole potential in phospholipid membranes.
PubMed:Hepatoprotective activity of polyhydroxylated 2-styrylchromones against tert-butylhydroperoxide induced toxicity in freshly isolated rat hepatocytes.
PubMed:Flavonoids inhibit VEGF/bFGF-induced angiogenesis in vitro by inhibiting the matrix-degrading proteases.
PubMed:Solvent influence on excited-state intramolecular proton transfer in 3-hydroxychromone derivatives studied by cryogenic high-resolution fluorescence spectroscopy.
PubMed:Perturbation of planarity as the possible mechanism of solvent-dependent variations of fluorescence quantum yield in 2-aryl-3-hydroxychromones.
PubMed:Protective effects of flavonoids on the cytotoxicity of linoleic acid hydroperoxide toward rat pheochromocytoma PC12 cells.
PubMed:Novel two-band ratiometric fluorescence probes with different location and orientation in phospholipid membranes.
PubMed:Electrochromic modulation of excited-state intramolecular proton transfer: the new principle in design of fluorescence sensors.
PubMed:Two new 5-deoxyflavones from Albizia odoratissima.
PubMed:Flavonoids suppress the cytotoxicity of linoleic acid hydroperoxide toward PC12 cells.
PubMed:7-OH-flavone is sulfated in the human liver and duodenum, whereas 5-OH-flavone and 3-OH-flavone are potent inhibitors of SULT1A1 activity and 7-OH-flavone sulfation rate.
PubMed:Effect of simple phenolic compounds on azoxymethane-induced aberrant crypt foci in rat colon.
PubMed:Neutral fluorescence probe with strong ratiometric response to surface charge of phospholipid membranes.
PubMed:Covalent alteration of the CYP3A4 active site: evidence for multiple substrate binding domains.
PubMed:Protein-flavonol interaction: fluorescence spectroscopic study.
PubMed:Flavonoids as peroxynitrite scavengers: the role of the hydroxyl groups.
PubMed:Conformational and spectroscopic investigation of 3-hydroxyflavone-aluminium chelates.
PubMed:Induction of apoptosis by flavones, flavonols (3-hydroxyflavones) and isoprenoid-substituted flavonoids in human oral tumor cell lines.
PubMed:Effects of flavonoids on the growth and cell cycle of cancer cells.
PubMed:Structure-activity relationship of cardiotonic flavonoids in guinea-pig papillary muscle.
PubMed:Phytoestrogens and inhibition of angiogenesis.
PubMed:Anti-inflammatory activity of flavone and some of its derivates from Virola michelli Heckel.
PubMed:Inhibition of methoxyresorufin demethylase activity by flavonoids in human liver microsomes.
PubMed:Cation adducts of mitochondrial ATPase subunit c: is subunit c a proton/cation exchanger?
PubMed:Flavonoids, dietary-derived inhibitors of cell proliferation and in vitro angiogenesis.
PubMed:Energy transfer to a proton-transfer fluorescence probe: tryptophan to a flavonol in human serum albumin.
PubMed:Interaction of organotins with a vacuolar-type H(+)-ATPase.
PubMed:Interaction of dibutyltin-3-hydroxyflavone bromide with the 16 kDa proteolipid indicates the disposition of proton translocation sites of the vacuolar ATPase.
PubMed:Interplay between excited-state intramolecular proton transfer and charge transfer in flavonols and their use as protein-binding-site fluorescence probes.
PubMed:Venturicidin titrates a redox cofactor of mitochondrial ATP synthase.
PubMed:Fo membrane domain of ATP synthase from bovine heart mitochondria: purification, subunit composition, and reconstitution with F1-ATPase.
PubMed:Dibutyltin-3-hydroxyflavone titrates a dissociable component (cofactor) of ATP synthase: an energy transfer component linked to the ubiquinone pool.
PubMed:A method to screen for the antioxidant effect of compounds on low-density lipoprotein (LDL): illustration with flavonoids.
PubMed:Interaction of vacuolar-type H(+)-ATPases with fluorescent organotin-flavone complexes.
PubMed:Inhibition of rat liver cyclic AMP-dependent protein kinase by flavonoids.
PubMed:Microbiological transformation of (+/-)-flavanone and (+/-)-isoflavanone.
PubMed:Effects of flavonoids on nonenzymatic lipid peroxidation: structure-activity relationship.
PubMed:Proton-transfer spectroscopy of 3-hydroxyflavone in an isolated-site crystal matrix.
PubMed:Mechanism of four-level laser action in solution excimer and excited-state proton-transfer cases.
PubMed:Factors affecting the toxic effect of tin on estuarine microorganisms.
PubMed:Mutagenicities of 61 flavonoids and 11 related compounds.
PubMed:Degradation of 3-hydroxyflavone by horse radish peroxidase.
PubMed:[2'-hydroxychalcone and 3-hydroxyflavone sulfonic acid derivatives (author's transl)].
 
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