EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

sinapinic acid
4-hydroxy-3,5-dimethoxycinnamic acid

Supplier Sponsors

Name:3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoic acid
CAS Number: 530-59-6Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:208-487-3
FDA UNII: 68A28V6010
Beilstein Number:2699118
MDL:MFCD00004401
XlogP3-AA:1.50 (est)
Molecular Weight:224.21264000
Formula:C11 H12 O5
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
EFSA/JECFA Comments:
(Z)- or (E)- isomer not specified by CASrn in Register. Mixture of E- and Z-isomers (EFFA, 2010a). Composition of stereoisomeric mixture to be specified.
Category:flavoring agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
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Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
DG SANTE Food Flavourings:08.088 4-hydroxy-3,5-dimethoxycinnamic acid
 
Physical Properties:
Appearance:yellow to tan crystalline powder (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 192.00 °C. @ 760.00 mm Hg
Boiling Point: 490.00 °C. @ 760.00 mm Hg
Flash Point: 317.00 °F. TCC ( 158.33 °C. )
logP (o/w): 0.997 (est)
Soluble in:
 alcohol
 water, 7082 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor Strength:none
Odor Description:at 100.00 %. odorless
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: skin conditioning
 
Suppliers:
Alfa Biotechnology
For experimental / research use only.
Sinapic acid 98%
BOC Sciences
For experimental / research use only.
Sinapic acid >98%
Coompo
For experimental / research use only.
Sinapic Acid from Plants ≥98%
ExtraSynthese
For experimental / research use only.
Sinapic acid (HPLC) ≥95%
Penta International
3,5-DIMETHOXY-4-HYDROXYCINNAMIC ACID
Santa Cruz Biotechnology
For experimental / research use only.
Sinapic acid ≥98%
Sigma-Aldrich: Aldrich
For experimental / research use only.
Sinapic acid 98% (titration), powder
sds
TCI AMERICA
For experimental / research use only.
3,5-Dimethoxy-4-hydroxycinnamic Acid >98.0%(GC)(T)
sds
 
Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
Xi - Irritant
R 36/37/38 - Irritating to eyes, respiratory system, and skin.
S 02 - Keep out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 37/39 - Wear suitable gloves and eye/face protection.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
flavoring agents
Recommendation for sinapinic acid usage levels up to:
 not for fragrance use.
 
Maximised Survey-derived Daily Intakes (MSDI-EU): 0.012 (μg/capita/day)
Modified Theoretical Added Maximum Daily Intake (mTAMDI): 3200 (μg/person/day)
Threshold of Concern:1800 (μg/person/day)
Structure Class: I
 
Food categories according to Commission Regulation EC No. 1565/2000 (EC, 2000) in FGE.06 (EFSA, 2002a). According to the Industry the "normal" use is defined as the average of reported usages and "maximum use" is defined as the 95th percentile of reported usages (EFSA, 2002i).
Note: mg/kg = 0.001/1000 = 0.000001 = 1/1000000 = ppm.
 average usage mg/kgmaximum usage mg/kg
Dairy products, excluding products of category 02.0 (01.0): 3.0000015.00000
Fats and oils, and fat emulsions (type water-in-oil) (02.0): 2.0000010.00000
Edible ices, including sherbet and sorbet (03.0): 3.0000015.00000
Processed fruit (04.1): 2.0000010.00000
Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2): --
Confectionery (05.0): 10.0000050.00000
Chewing gum (05.3): --
Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0): 5.0000025.00000
Bakery wares (07.0): 10.0000050.00000
Meat and meat products, including poultry and game (08.0): 2.0000010.00000
Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0): 2.0000010.00000
Eggs and egg products (10.0): --
Sweeteners, including honey (11.0): --
Salts, spices, soups, sauces, salads, protein products, etc. (12.0): 5.0000025.00000
Foodstuffs intended for particular nutritional uses (13.0): 10.0000050.00000
Non-alcoholic ("soft") beverages, excl. dairy products (14.1): 3.0000015.00000
Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2): 10.0000050.00000
Ready-to-eat savouries (15.0): 15.0000075.00000
Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0): 5.0000025.00000
 
Safety References:
European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...

European Food Safety Authority (EFSA) reference(s):

Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Flavouring Group Evaluation 15 (FGE.15): Aryl-substituted saturated and unsaturated primary alcohol/aldehyde/acid/ester derivatives from chemical group 22 (Commission Regulation (EC) No 1565/2000 of 18 July 2000)
View page or View pdf

Flavouring Group Evaluation 55 (FGE.55): Consideration of phenyl-substituted aliphatic alcohols and related aldehydes and esters evaluated by JECFA (63rd meeting) structurally related to phenethyl alcohol, aldehyde, esters and related phenylacetic acid esters evaluated by EFSA in FGE.14 (2005) and aryl-substituted saturated and unsaturated primary alcohol/aldehyde/acid/ester derivatives evaluated by EFSA in FGE.15 (2005) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC)
View page or View pdf

Flavouring Group Evaluation 15, Revision 1 (FGE.15Rev1) - Aryl-substituted saturated and unsaturated primary alcohol/aldehyde/acid/ester derivatives from chemical group 22 - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC)
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 68 (FGE.68): Consideration of cinnamyl alcohol and related flavouring agents evaluated by JECFA (55th meeting) evaluated by EFSA in FGE.15Rev1 (2008)
View page or View pdf

Flavouring Group Evaluation 15, Revision 2 (FGE.15Rev2): Aryl-substituted saturated and unsaturated primary alcohol/aldehyde/acid/ester derivatives from chemical group 22
View page or View pdf

EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :10743
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoic acid
Chemidplus:0000530596
 
References:
 3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoic acid
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):10743
Pubchem (sid):134976317
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
Golm Metabolome Database:Search
Metabolomics Database:Search
KEGG (GenomeNet):C00482
HMDB (The Human Metabolome Database):HMDB32616
Export Tariff Code:2918.29.7500
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 apple fruit
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 barley plant
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 bean fava bean plant
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 beer - up to 0.3 mg/kg
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 bilberry leaf
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 brassica oleracea
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 broccoli asparagus broccoli leaf
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 brussel sprout leaf
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 cabbage leaf
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 cacao plant
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 cardamom leaf
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 celery plant
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 chamomile sweet false chamomile plant
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 chicory plant
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 coffee plant
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 corn plant
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 cress garden cress
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 cress garden cress seed
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 fennel seed
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 flax seed
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 garlic bulb
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 garlic plant
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 grape root
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 horseradish plant
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 leek wild leek plant
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 lemon fruit
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 mustard white mustard seed
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 oat seed
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 olive fruit
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 onion bulb
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 onion leaf
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 onion root
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 orange fruit
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 orange fruit juice
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 orange pericarp
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 pea seed
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 peanut seed
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 pineapple fruit
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 poppy opium poppy pericarp
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 potato tuber
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 purslane plant
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 radish root
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 rhubarb plant
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 rhubarb root
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 soybean - up to 13 mg/kg
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 soybean leaf
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 soybean seed
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 star fruit plant
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 sunflower seed
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 tarragon plant
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 walnut english walnut nut
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 walnut english walnut testa
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 wheat seed
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 wine - up to 10 mg/kg
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Synonyms:
3,5-dimethoxy-4-hydroxycinnamic acid
4-hydroxy-3,5-dimethoxycinnamic acid
3-(4-hydroxy-3,5-dimethoxyphenyl) prop-2-enoic acid
3-(4-hydroxy-3,5-dimethoxyphenyl)-2-propenoic acid
3-(4-hydroxy-3,5-dimethoxyphenyl)acrylic acid
3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoic acid
2-propenoic acid, 3-(4-hydroxy-3,5-dimethoxyphenyl)-
 sinapic acid
 

Articles:

PubMed:[Chemical constituents from seeds of Brassica campestris].
PubMed:Acylated anthocyanins from sprouts of Raphanus sativus cv. Sango: isolation, structure elucidation and antioxidant activity.
PubMed:Enhanced laccase production by Trametes versicolor using corn steep liquor as both nitrogen source and inducer.
PubMed:Spectral reproducibility and quantification of peptides in MALDI of samples prepared by micro-spotting.
PubMed:Matrix pre-coated targets for high throughput MALDI imaging of proteins.
PubMed:Synthesis of hydroxycinnamoyl β-D-xylopyranosides and evaluation of their antioxidant properties.
PubMed:Improved sample preparation for intact cell mass spectrometry (biotyping) of mycelium samples taken from a batch fermentation process of Penicillium chrysogenum.
PubMed:Laser desorption/ionization mass spectrometric analysis of folic acid, vancomycin and Triton® X-100 on variously functionalized carbon nanotubes.
PubMed:Matrix-assisted laser desorption/ionization time-of-flight mass spectrometric imaging of synthetic polymer sample spots prepared using ionic liquid matrices.
PubMed:Photoresponsive wettability in monolayer films from sinapinic acid.
PubMed:Sinapinic acid-directed synthesis of gold nanoclusters and their application to quantitative matrix-assisted laser desorption/ionization mass spectrometry.
PubMed:Antihyperglycemic action of sinapic acid in diabetic rats.
PubMed:Z-sinapinic acid: the change of the stereochemistry of cinnamic acids as rational synthesis of a new matrix for carbohydrate MALDI-MS analysis.
PubMed:Histone deacetylase (HDAC) inhibitory and antiproliferative activities of phenolic-rich extracts derived from the rhizome of Hydnophytum formicarum Jack.: sinapinic acid acts as HDAC inhibitor.
PubMed:High-resolution screening combined with HPLC-HRMS-SPE-NMR for identification of potential health-promoting constituents in sea aster and searocket--new Nordic food ingredients.
PubMed:Effects of different tannin-rich extracts and rapeseed tannin monomers on methane formation and microbial protein synthesis in vitro.
PubMed:A thiophene-containing compound as a matrix for matrix-assisted laser desorption/ ionization mass spectrometry and the electrical conductivity of matrix crystals.
PubMed:Principle component analysis combined with matrix-assisted laser desorption ionization mass spectrometry for rapid diagnosing the sera of patients with major depression.
PubMed:Simple fabrication of hydrophobic surface target for increased sensitivity and homogeneity in matrix-assisted laser desorption/ionization time-of-flight mass spectrometry analysis of peptides, phosphopeptides, carbohydrates and proteins.
PubMed:α-Cyano-4-hydroxycinnamic acid, sinapinic acid, and ferulic acid as matrices and alkylating agents for matrix-assisted laser desorption/ionization time-of-flight mass spectrometric analysis of cysteine-containing peptides.
PubMed:Assessment of the anti-invasion potential and mechanism of select cinnamic acid derivatives on human lung adenocarcinoma cells.
PubMed:Repeat MALDI MS imaging of a single tissue section using multiple matrices and tissue washes.
PubMed:Effect of sinapic acid against carbon tetrachloride-induced acute hepatic injury in rats.
PubMed:Antioxidant extraction from mustard (Brassica juncea) seed meal using high-intensity ultrasound.
PubMed:A newly synthesized sinapic acid derivative inhibits endothelial activation in vitro and in vivo.
PubMed:Synthesis and application of ionic liquid matrices (ILMs) for effective pathogenic bacteria analysis in matrix assisted laser desorption/ionization (MALDI-MS).
PubMed:Effect of sinapic acid against dimethylnitrosamine-induced hepatic fibrosis in rats.
PubMed:Phytosteryl sinapates and vanillates: chemoenzymatic synthesis and antioxidant capacity assessment.
PubMed:Detection of high molecular weight proteins by MALDI imaging mass spectrometry.
PubMed:Sonochemical effects on free phenolic acids under ultrasound treatment in a model system.
PubMed:Laser desorption/ionization mass spectrometric analysis of surfactants on functionalized carbon nanotubes.
PubMed:Evidence for lignin oxidation by the giant panda fecal microbiome.
PubMed:Prediction model based on decision tree analysis for laccase mediators.
PubMed:Protective effects of sinapic acid on cardiac hypertrophy, dyslipidaemia and altered electrocardiogram in isoproterenol-induced myocardial infarcted rats.
PubMed:MALDI imaging in human skin tissue sections: focus on various matrices and enzymes.
PubMed:Comparison of sample preparation methods and evaluation of intra- and intersample reproducibility in bacteria MALDI-MS profiling.
PubMed:Possible evidence of amide bond formation between sinapinic acid and lysine-containing bacterial proteins by matrix-assisted laser desorption/ionization (MALDI) at 355 nm.
PubMed:[Changes in phenolic acids during maturation and lignification of Scots pine xylem].
PubMed:Neuroprotective effect of sinapic acid in a mouse model of amyloid β(1-42) protein-induced Alzheimer's disease.
PubMed:Synthesis of glycosyl ferulate derivatives by amine-promoted glycosylation with regioselective hydrolysis using Novozym 435 and evaluation of their antioxidant properties.
PubMed:Protective effects of sinapic acid on lysosomal dysfunction in isoproterenol induced myocardial infarcted rats.
PubMed:Potential for food-drug interactions by dietary phenolic acids on human organic anion transporters 1 (SLC22A6), 3 (SLC22A8), and 4 (SLC22A11).
PubMed:Nitrate reductase- and nitric oxide-dependent activation of sinapoylglucose:malate sinapoyltransferase in leaves of Arabidopsis thaliana.
PubMed:Synthesis of phenolic acid conjugated chitooligosaccharides and evaluation of their antioxidant activity.
PubMed:Analysis of initial reactions of MALDI based on chemical properties of matrixes and excitation condition.
PubMed:Benzoylation and sinapoylation of glucosinolate R-groups in Arabidopsis.
PubMed:Comparison of phenolic acids profile and antioxidant potential of six varieties of spelt (Triticum spelta L.).
PubMed:UVR8 mediates UV-B-induced Arabidopsis defense responses against Botrytis cinerea by controlling sinapate accumulation.
PubMed:High ion yields of carbohydrates from frozen solution by UV-MALDI.
PubMed:N-Caffeoyl serotonin as selective COX-2 inhibitor.
PubMed:Separation, identification, and quantitation of phenolic acids in Chinese waxberry (Myrica Rubra) juice by HPLC-PDA-ESI-MS.
PubMed:Sublimation of new matrix candidates for high spatial resolution imaging mass spectrometry of lipids: enhanced information in both positive and negative polarities after 1,5-diaminonapthalene deposition.
PubMed:Phenolic composition and antioxidant effect of aqueous extract of Arisaema cum Bile, the Oriental Herb Medicine, in human fibroblast cells.
PubMed:Matrix-assisted laser desorption/ionization mass spectrometry reveals decreased calcylcin expression in small cell lung cancer.
PubMed:Compelling advantages of negative ion mode detection in high-mass MALDI-MS for homomeric protein complexes.
PubMed:Alteration in lipid and protein profiles of ovarian cancer: similarity to breast cancer.
PubMed:Saliva analysis by surface-enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF-MS) in orthodontic treatment: first pilot study.
PubMed:Protein and lipid MALDI profiles classify breast cancers according to the intrinsic subtype.
PubMed:Capillary-channeled polymer (C-CP) films as processing platforms for protein analysis by matrix-assisted laser/desorption ionization mass spectrometry (MALDI-MS).
PubMed:1064 nm dispersive multichannel Raman spectroscopy for the analysis of plant lignin.
PubMed:Determination of low-molecular mass phenols in red wines: the influence of chips, staves and micro-oxygenation aging tank.
PubMed:Expansion cooling in the matrix plume is under-recognized in MALDI mass spectrometry.
PubMed:Fast quantitative determination of melamine and its derivatives by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
PubMed:Protein UTLC-MALDI-MS using thin films of submicrometer silica particles.
PubMed:Protective role of sinapic acid against arsenic: induced toxicity in rats.
PubMed:Histology-directed matrix-assisted laser desorption/ionization analysis reveals tissue origin and p53 status of primary liver cancers.
PubMed:Metabolite profiling of Arabidopsis seedlings in response to exogenous sinalbin and sulfur deficiency.
PubMed:Elucidating the role of metals in Alzheimer's disease through the use of Surface-Enhanced Laser Desorption/Ionisation time-of-flight mass spectrometry.
PubMed:The protein profile of Theobroma cacao L. seeds as obtained by matrix-assisted laser desorption/ionization mass spectrometry.
PubMed:Matrix sublimation/recrystallization for imaging proteins by mass spectrometry at high spatial resolution.
PubMed:Mechanism and kinetics studies on the antioxidant activity of sinapinic acid.
PubMed:Interaction and solubilization of some phenolic antioxidants in Pluronic® micelles.
PubMed:Distinct substrate specificities and unusual substrate flexibilities of two hydroxycinnamoyltransferases, rosmarinic acid synthase and hydroxycinnamoyl-CoA:shikimate hydroxycinnamoyl-transferase, from Coleus blumei Benth.
PubMed:Optimization of mass spectral features in MALDI-TOF MS profiling of Acinetobacter species.
PubMed:Improvement of leucocyte functions in mature and old mice after 15 and 30 weeks of diet supplementation with polyphenol-rich biscuits.
PubMed:Bioprocessing of wheat bran in whole wheat bread increases the bioavailability of phenolic acids in men and exerts antiinflammatory effects ex vivo.
PubMed:Bioconversion of cinnamic acid derivatives by Schizophyllum commune.
PubMed:MALDI imaging and profiling MS of higher mass proteins from tissue.
PubMed:Competing ultrafast photoinduced quenching reactions in cinnamic acid : peptide blends.
PubMed:Phenol-oxidizing laccases from the termite gut.
PubMed:Initial ionization reaction in matrix-assisted laser desorption/ionization.
PubMed:Ionic liquid matrices for MALDI-TOF-MS analysis of intact glycoproteins.
PubMed:Sinapate esters in brassicaceous plants: biochemistry, molecular biology, evolution and metabolic engineering.
PubMed:Capillary electrophoresis/mass spectrometry for the separation and characterization of bovine Cu,Zn-superoxide dismutase.
PubMed:Sinapic acid attenuates kainic acid-induced hippocampal neuronal damage in mice.
PubMed:In-source decay and fragmentation characteristics of peptides using 5-aminosalicylic acid as a matrix in matrix-assisted laser desorption/ionization mass spectrometry.
PubMed:Covalent attachment and dissociative loss of sinapinic acid to/from cysteine-containing proteins from bacterial cell lysates analyzed by MALDI-TOF-TOF mass spectrometry.
PubMed:Fragmentation pathways of acylated flavonoid diglucuronides from leaves of Medicago truncatula.
PubMed:Improved detection of intact tyrosine sulfate-containing peptides by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry in linear negative ion mode.
PubMed:Sinapinic acid can replace ascorbate in the biotin switch assay.
PubMed:A new method for analysis of disulfide-containing proteins by matrix-assisted laser desorption ionization (MALDI) mass spectrometry.
PubMed:Study of human neutrophil peptides in saliva by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
PubMed:Optimal preparation methods for automated matrix-assisted laser desorption/ionization time-of-flight mass spectrometry profiling of low molecular weight proteins and peptides.
PubMed:Application of laccase-natural mediator systems to sisal pulp: an effective approach to biobleaching or functionalizing pulp fibres?
PubMed:Bioprocessing of wheat bran improves in vitro bioaccessibility and colonic metabolism of phenolic compounds.
PubMed:Hydroxycinnamic acid amides with oxazole-containing amino acid: synthesis and antioxidant activity.
PubMed:RNAi-mediated suppression of DET1 alters the levels of carotenoids and sinapate esters in seeds of Brassica napus.
PubMed:Dependence of the ejection velocities of laser-ablated ions on the laser wavelength and fluence.
PubMed:The effect of sodium dodecyl sulfate and anion-exchange silica gel on matrix-assisted laser desorption/ionization mass spectrometric analysis of proteins.
PubMed:Analysis of chlorophylls and their derivatives by matrix-assisted laser desorption/ionization-time-of-flight mass spectrometry.
PubMed:Analysis of melamine cyanurate in urine using matrix-assisted laser desorption/ionization mass spectrometry.
PubMed:MALDI imaging mass spectrometry of integral membrane proteins from ocular lens and retinal tissue.
PubMed:Identification of the antioxidation reaction products from a sinapic ester in a lipid oxidation system.
PubMed:Temperature of peptide ions generated by matrix-assisted laser desorption ionization and their dissociation kinetic parameters.
PubMed:Imaging mass spectrometry using chemical inkjet printing reveals differential protein expression in human oral squamous cell carcinoma.
PubMed:The effect of temperature on the stability of compounds used as UV-MALDI-MS matrix: 2,5-dihydroxybenzoic acid, 2,4,6-trihydroxyacetophenone, alpha-cyano-4-hydroxycinnamic acid, 3,5-dimethoxy-4-hydroxycinnamic acid, nor-harmane and harmane.
PubMed:Using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry to rapidly screen for albuminuria.
PubMed:Development of a multi-frequency laser for use in MALDI-TOFMS.
PubMed:Rapid classification and identification of salmonellae at the species and subspecies levels by whole-cell matrix-assisted laser desorption ionization-time of flight mass spectrometry .
PubMed:Improved MALDI-TOF imaging yields increased protein signals at high molecular mass.
PubMed:Anti-inflammatory effects of sinapic acid through the suppression of inducible nitric oxide synthase, cyclooxygase-2, and proinflammatory cytokines expressions via nuclear factor-kappaB inactivation.
PubMed:Feruloyl esterase-catalysed synthesis of glycerol sinapate using ionic liquids mixtures.
PubMed:Differentiation of Streptococcus pneumoniae conjunctivitis outbreak isolates by matrix-assisted laser desorption ionization-time of flight mass spectrometry.
PubMed:MALDI-TOF mass signatures for differentiation of yeast species, strain grouping and monitoring of morphogenesis markers.
PubMed:Simultaneous analysis of vitamins and caffeine in energy drinks by surfactant-mediated matrix-assisted laser desorption/ionization.
PubMed:Metabolomics provide new insight on the metabolism of dietary phytochemicals in rats.
PubMed:Ultrahigh-pressure liquid chromatography of isoflavones and phenolic acids on different stationary phases.
PubMed:Antioxidant potential of hydroxycinnamic acid glycoside esters.
PubMed:Competing ion decomposition channels in matrix-assisted laser desorption ionization.
PubMed:Tronchuda cabbage (Brassica oleracea L. var. costata DC): scavenger of reactive nitrogen species.
PubMed:The effect of dietary sinapic acid (4-hydroxy-3, 5-dimethoxy-cinnamic acid) on gastrointestinal tract microbial fermentation, nutrient utilization, and egg quality in laying hens.
PubMed:Nutritional and physiological effects of dietary sinapic acid (4-hydroxy-3,5-dimethoxy-cinnamic acid) in broiler chickens and its metabolism in the digestive tract.
PubMed:Two new compounds from Cynanchum amplexicaule.
PubMed:Application of ProteinChip array profiling in serum biomarker discovery for patients suffering from severe acute respiratory syndrome.
PubMed:Imaging mass spectrometry of proteins and peptides: 3D volume reconstruction.
PubMed:Parameters contributing to efficient ion generation in aerosol MALDI mass spectrometry.
PubMed:Rational selection of the optimum MALDI matrix for top-down proteomics by in-source decay.
PubMed:Nitrogen and fungicide applications against Erysiphe cruciferarum affect quality components of oilseed rape.
PubMed:Direct visualisation of peptide hormones in cultured pancreatic islet alpha- and beta-cells by intact-cell mass spectrometry.
PubMed:Sinapic acid derivatives from the seeds of Raphanus nussatirus L.
PubMed:Letter: influence of experimental parameters on identification of whole cell Rhizobium by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
PubMed:Towards a reliable molecular mass determination of intact glycoproteins by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
PubMed:Use of reference compounds in antioxidant activity assessment.
PubMed:Anxiolytic-like effects of sinapic acid in mice.
PubMed:Analysis of erlotinib and its metabolites in rat tissue sections by MALDI quadrupole time-of-flight mass spectrometry.
PubMed:Binding, tuning and mechanical function of the 4-hydroxy-cinnamic acid chromophore in photoactive yellow protein.
PubMed:Dissipation of charge on MALDI-TOF polymeric chips using an electron-acceptor: analysis of proteins.
PubMed:Cerebral protective and cognition-improving effects of sinapic acid in rodents.
PubMed:In vivo analysis and spatial profiling of phytochemicals in herbal tissue by matrix-assisted laser desorption/ionization mass spectrometry.
PubMed:Biotransformation of sinapic acid catalyzed by Momordica charantia peroxidase.
PubMed:Matrix-assisted laser desorption/ionization-mass spectrometry of hydrophobic proteins in mixtures using formic acid, perfluorooctanoic acid, and sorbitol.
PubMed:The hyper-fluorescent trichome phenotype of the brt1 mutant of Arabidopsis is the result of a defect in a sinapic acid: UDPG glucosyltransferase.
PubMed:General Method for MALDI-MS Analysis of Proteins and Peptides.
PubMed:Ion yields of thin MALDI samples: dependence on matrix and metal substrate and implications for models.
PubMed:Electroelution of intact proteins from SDS-PAGE gels and their subsequent MALDI-TOF MS analysis.
PubMed:Piezoelectric ink jet processing of materials for medical and biological applications.
PubMed:Protein extraction from Mycobacterium avium subsp. paratuberculosis: Comparison of methods for analysis by sodium dodecyl sulphate polyacrylamide gel electrophoresis, native PAGE and surface enhanced laser desorption/ionization time of flight mass spectrometry.
PubMed:Ultrafast dynamics of isolated model photoactive yellow protein chromophores: "Chemical perturbation theory" in the laboratory.
PubMed:Ionic (liquid) matrices for matrix-assisted laser desorption/ionization mass spectrometry-applications and perspectives.
PubMed:Conversion of sinapic acid to syringic acid by a filamentous fungus Paecilomyces variotii.
PubMed:Esterification of ferulic acid with polyols using a ferulic acid esterase from Aspergillus niger.
PubMed:Optimization and evaluation of surface-enhanced laser-desorption/ionization time-of-flight mass spectrometry for protein profiling of cerebrospinal fluid.
PubMed:Molecular dynamics simulation of laser desorption of a fragment of protein kinase A from two MALDI matrices.
PubMed:Three-layer matrix/sample preparation method for MALDI MS analysis of low nanomolar protein samples.
PubMed:Proteomic analysis of rat plasma by SELDI-TOF-MS under the condition of prevention of progressive adriamycin nephropathy using oral adsorbent AST-120.
PubMed:Modeling suberization with peroxidase-catalyzed polymerization of hydroxycinnamic acids: cross-coupling and dimerization reactions.
PubMed:Optimization of MALDI-TOF MS for strain level differentiation of Arthrobacter isolates.
PubMed:Solid ionic matrixes for direct tissue analysis and MALDI imaging.
PubMed:Derivatized cellulose combined with MALDI-TOF MS: a new tool for serum protein profiling.
PubMed:Characterization of intact Penicillium spores by matrix-assisted laser desorption/ionization mass spectrometry.
PubMed:Characterization in vitro and in vivo of the putative multigene 4-coumarate:CoA ligase network in Arabidopsis: syringyl lignin and sinapate/sinapyl alcohol derivative formation.
PubMed:Fluctuations of different endogenous phenolic compounds and cinnamic acid in the first days of the rooting process of cherry rootstock 'GiSelA 5' leafy cuttings.
PubMed:Spectroscopic investigation of the interaction between human serum albumin and three organic acids.
PubMed:Formation of a complex pattern of sinapate esters in Brassica napus seeds, catalyzed by enzymes of a serine carboxypeptidase-like acyltransferase family?
PubMed:The detection of nitrated tyrosine in neuropeptides: a MALDI matrix-dependent response.
PubMed:A novel approach to identify plant parasitic nematodes using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
PubMed:Nucleolin undergoes partial N- and O-glycosylations in the extranuclear cell compartment.
PubMed:A blend of polyphenolic compounds explains the stimulatory effect of red wine on human endothelial NO synthase.
PubMed:Characterization of some synthetic Ru and Ir complexes by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
PubMed:The copigmentation effect of sinapic acid on malvin: a spectroscopic investigation on colour enhancement.
PubMed:High-performance liquid chromatographic determination of phenolic compounds in rice.
PubMed:MALDI mass spectrometry in the solution of some forensic problems.
PubMed:Comparison of physico-chemical characteristics of four laccases from different basidiomycetes.
PubMed:Characterization of humic substances by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
PubMed:A simple and inexpensive approach to interfacing high-performance liquid chromatography and matrix-assisted laser desorption/ionization-time of flight-mass spectrometry.
PubMed:Laccase of Coriolus zonatus: isolation, purification, and some physicochemical properties.
PubMed:Matrix-dependent cationization in MALDI mass spectrometry.
PubMed:MALDI-MS analysis of peptides modified with photolabile arylazido groups.
PubMed:Analysis of phenolic compounds in white rice, brown rice, and germinated brown rice.
PubMed:4-Coumarate:coenzyme A ligase in black locust (Robinia pseudoacacia) catalyses the conversion of sinapate to sinapoyl-CoA.
PubMed:Ex planta phytoremediation of trichlorophenol and phenolic allelochemicals via an engineered secretory laccase.
PubMed:Quantitative determination of heme for forensic characterization of bacillus spores using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
PubMed:Stability and enhancement of berry juice color.
PubMed:Analysis of differential protein expression in Actinobacillus pleuropneumoniae by Surface Enhanced Laser Desorption Ionisation--ProteinChip (SELDI) technology.
PubMed:4-hydroxycinnamic ethyl ester derivatives and related dehydrodimers: Relationship between oxidation potential and protective effects against oxidation of low-density lipoproteins.
PubMed:Proteomic analysis of kappa-casein micro-heterogeneity.
PubMed:The 4-coumarate:CoA ligase gene family in Arabidopsis thaliana comprises one rare, sinapate-activating and three commonly occurring isoenzymes.
PubMed:Qualitative and quantitative analysis of low molecular weight compounds by ultraviolet matrix-assisted laser desorption/ionization mass spectrometry using ionic liquid matrices.
PubMed:The Arabidopsis thaliana REDUCED EPIDERMAL FLUORESCENCE1 gene encodes an aldehyde dehydrogenase involved in ferulic acid and sinapic acid biosynthesis.
PubMed:Spatial profiling with MALDI MS: distribution of neuropeptides within single neurons.
PubMed:Synthesis of lipophilic clovamide derivatives and their antioxidative potential against lipid peroxidation.
PubMed:Antioxidant constituents of radish sprout (Kaiware-daikon), Raphanus sativus L.
PubMed:Detection of immune complexes by matrix-assisted laser desorption/ionization mass spectrometry.
PubMed:A high-performance matrix-assisted laser desorption/ionization orthogonal time-of-flight mass spectrometer with collisional cooling.
PubMed:Direct analysis of drug candidates in tissue by matrix-assisted laser desorption/ionization mass spectrometry.
PubMed:Absorption of hydroxycinnamates in humans after high-bran cereal consumption.
PubMed:[Studies on the phenolic acid constituents from Chinese medicine "sheng-ma", rhizome of Cimicifuga foetida L].
PubMed:Hypochlorite scavenging activity of hydroxycinnamic acids evaluated by a rapid microplate method based on the measurement of chloramines.
PubMed:Peroxynitrite and NO+ donors form colored nitrite adducts with sinapinic acid: potential applications.
PubMed:Ligand screening by exoproteolysis and mass spectrometry in combination with computer modelling.
PubMed:The substrate specificity-determining amino acid code of 4-coumarate:CoA ligase.
PubMed:Arabidopsis glucosyltransferases with activities toward both endogenous and xenobiotic substrates.
PubMed:Some aspects of the stability of ion current in a matrix-assisted laser desorption/ionization source.
PubMed:Comparison of laser desorption and matrix-assisted laser desorption/ionization for ruthenium and osmium trisbipyridine complexes using Fourier transform mass spectrometry.
PubMed:Improved detection of higher molecular weight proteins by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry on polytetrafluoroethylene surfaces.
PubMed:Sinapate dehydrodimers and sinapate-ferulate heterodimers in cereal dietary fiber.
PubMed:Avenanthramides in oats (Avena sativa L.) and structure-antioxidant activity relationships.
PubMed:Multiform biosynthetic pathway of syringyl lignin in angiosperms.
PubMed:Internal energy of ions generated by matrix-assisted laser desorption/ionization.
PubMed:O-4-Linked coniferyl and sinapyl aldehydes in lignifying cell walls are the main targets of the Wiesner (phloroglucinol-HCl) reaction.
PubMed:Isolation and identification of DPPH radical scavenging compounds in Kurosu (Japanese unpolished rice vinegar).
PubMed:Peroxynitrite scavenging activity of sinapic acid (3,5-dimethoxy-4-hydroxycinnamic acid) isolated from Brassica juncea.
PubMed:Biosynthesis of podophyllotoxin in Linum album cell cultures.
PubMed:Direct profiling and imaging of peptides and proteins from mammalian cells and tissue sections by mass spectrometry.
PubMed:Interactions of lipoic acid radical cations with vitamins C and E analogue and hydroxycinnamic acid derivatives.
PubMed:[Studies on the chemical constituents from Sophora flavescens ait].
PubMed:Cloning and characterization of the ferulic acid catabolic genes of Sphingomonas paucimobilis SYK-6.
PubMed:Small angle neutron scattering measurements of synthetic polymer dispersions in matrix-assisted laser desorption/ionization matrixes.
PubMed:Direct surface analysis of fungal species by matrix-assisted laser desorption/ionization mass spectrometry.
PubMed:Sample preparation in matrix-assisted laser desorption/ionization mass spectrometry of whole bacterial cells and the detection of high mass (>20 kDa) proteins.
PubMed:Determination of free and total phenolic acids in plant-derived foods by HPLC with diode-array detection.
PubMed:A multigene family of glycosyltransferases in a model plant, Arabidopsis thaliana.
PubMed:Evidence for the biosynthetic pathway from sinapic acid to syringyl lignin using labeled sinapic acid with stable isotope at both methoxy groups in Robinia pseudoacacia and Nerium indicum.
PubMed:Investigation of the release of iron from ferritin by naturally occurring antioxidants.
PubMed:Changes in secondary metabolism and deposition of an unusual lignin in the ref8 mutant of Arabidopsis.
PubMed:The Arabidopsis REF8 gene encodes the 3-hydroxylase of phenylpropanoid metabolism.
PubMed:Rewriting the lignin roadmap.
PubMed:Formation of thomasidioic acid from dehydrosinapinic acid dilactone under neutral conditions, and a remaining inhibitory activity against peroxynitrite-mediated protein nitration.
PubMed:Antioxidant properties of ferulic acid and its related compounds.
PubMed:High performance liquid chromatography of phenolic choline ester fragments derived by chemical and enzymatic fragmentation processes: analysis of sinapine in rape seed.
PubMed:Analysis of the saliva from patients with oral cancer by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
PubMed:Mass spectrometry of nicotinic acetylcholine receptors and associated proteins as models for complex transmembrane proteins.
PubMed:Mutations that reduce sinapoylmalate accumulation in Arabidopsis thaliana define loci with diverse roles in phenylpropanoid metabolism.
PubMed:On-target endoglycosidase digestion matrix-assisted laser desorption/ionization mass spectrometry of glycopeptides.
PubMed:Detection of specific Bacillus anthracis spore biomarkers by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
PubMed:The sng2 mutant of Arabidopsis is defective in the gene encoding the serine carboxypeptidase-like protein sinapoylglucose:choline sinapoyltransferase.
PubMed:5-Ethyl-2-mercaptothiazole as matrix for matrix-assisted laser desorption/ionization of a broad spectrum of analytes in positive and negative ion mode.
PubMed:Laccases from Basidiomycetes: physicochemical characteristics and substrate specificity towards methoxyphenolic compounds.
PubMed:Ionic liquids as matrixes for matrix-assisted laser desorption/ionization mass spectrometry.
PubMed:Isolation and study of some properties of laccase from the basidiomycetes Cerrena maxima.
PubMed:Studies of pesticides by collision-induced dissociation, postsource-decay, matrix-assisted laser desorption/ionization time of flight mass spectrometry.
PubMed:Ab initio and density functional theory studies for the explanation of the antioxidant activity of certain phenolic acids.
PubMed:Application of capillary electrophoresis for separating 1-O-glycopyranosyl sinapate from rapeseed.
PubMed:Electron transfer vs. proton transfer within radical-cation clusters of guanosine and deoxyguanosine with substituted naphthalenes and sinapinic acid.
PubMed:Characterization of Aspergillus spores by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
PubMed:Ultraviolet-B radiation impacts light-mediated turnover of the photosystem II reaction center heterodimer in Arabidopsis mutants altered in phenolic metabolism.
PubMed:Identification of glucosyltransferase genes involved in sinapate metabolism and lignin synthesis in Arabidopsis.
PubMed:Cloning of the SNG1 gene of Arabidopsis reveals a role for a serine carboxypeptidase-like protein as an acyltransferase in secondary metabolism.
PubMed:Acyltransferases in protease's clothing.
PubMed:Modifications in lignin and accumulation of phenolic glucosides in poplar xylem upon down-regulation of caffeoyl-coenzyme A O-methyltransferase, an enzyme involved in lignin biosynthesis.
PubMed:Application of matrix-assisted laser desorption/ionization to on-line aerosol time-of-flight mass spectrometry
PubMed:Purification and characterization of an extracellular feruloyl esterase from the thermophilic anaerobe Clostridium stercorarium.
PubMed:Inhibition of aflatoxin biosynthesis by phenolic compounds.
PubMed:Direct profiling of proteins in biological tissue sections by MALDI mass spectrometry.
PubMed:Insight into absorption of radiation/energy transfer in infrared matrix-assisted laser desorption/ionization: the roles of matrices, water and metal substrates.
PubMed:Inhibitory mechanism of sinapinic acid against peroxynitrite-mediated tyrosine nitration of protein in vitro.
PubMed:Fingerprinting of Helicobacter pylori strains by matrix-assisted laser desorption/ionization mass spectrometric analysis.
PubMed:Homogeneous sample preparation for automated high throughput analysis with matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry.
PubMed:Transformation of 3,5-dimethoxy,4-hydroxy cinnamic acid by polyphenol oxidase from the fungus Trametes versicolor: product elucidation studies.
PubMed:Matrix-assisted laser desorption/ionization time-of-flight mass spectrometric analysis of phospholipase A2 and fibrinolytic enzyme, two enzymes obtained from Chinese Agkistrodon blomhoffii Ussurensis venom.
PubMed:Applications of in-source fragmentation of protein ions for direct sequence analysis by delayed extraction MALDI-TOF mass spectrometry.
PubMed:Mechanism of reaction of nitrogen dioxide radical with hydroxycinnamic acid derivatives: a pulse radiolysis study.
PubMed:Expression, characterization, and purification of C-terminally hexahistidine-tagged thromboxane A2 receptors.
PubMed:Purification and characterization of the constitutive form of laccase from the basidiomycete Coriolus hirsutus and effect of inducers on laccase synthesis.
PubMed:4-Coumarate:coenzyme A ligase in hybrid poplar. Properties of native enzymes, cDNA cloning, and analysis of recombinant enzymes.
PubMed:Matrix-assisted laser desorption ionization mass spectrometry for the analysis of monosulfated oligosaccharides.
PubMed:Supplementation with wine phenolic compounds increases the antioxidant capacity of plasma and vitamin E of low-density lipoprotein without changing the lipoprotein Cu(2+)-oxidizability: possible explanation by phenolic location.
PubMed:Enhancements of choline acetyltransferase activity and nerve growth factor secretion by Polygalae radix-extract containing active ingredients in Kami-untan-to.
PubMed:Analysis of recombinant DNA-derived glycoproteins via high-performance capillary electrophoresis coupled with off-line matrix-assisted laser desorption ionization time-of-flight mass spectrometry.
PubMed:Rapid profiling of E. coli proteins up to 500 kDa from whole cell lysates using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
PubMed:Sinapic acid ester metabolism in wild type and a sinapoylglucose-accumulating mutant of arabidopsis.
PubMed:Peptide nucleic acid characterization by MALDI-TOF mass spectrometry.
PubMed:Comparison of 3 methods for the determination of sinapic acid ester content in enzymatically treated canola meals.
PubMed:Ultraviolet matrix assisted laser desorption ionization-mass spectrometry of electroblotted proteins.
PubMed:Charge state distribution shifting of protein ions observed in matrix-assisted laser desorption ionization mass spectrometry.
PubMed:A procedure for selective DNA alkylation and detection by mass spectrometry.
PubMed:Facile, in situ matrix-assisted laser desorption ionization-mass spectrometry analysis and assignment of disulfide pairings in heteropeptide molecules.
PubMed:Prompt fragmentation of disulfide-linked peptides during matrix-assisted laser desorption ionization mass spectrometry.
PubMed:Mass determination of human immunoglobulin IgM using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
PubMed:Characterization of modified and normal deoxyoligonucleotides by MALDI, time-of-flight mass spectrometry.
PubMed:Structural characterization of polycyclic aromatic hydrocarbon dihydrodiol epoxide DNA adducts using matrix-assisted laser desorption/ionization Fourier transform mass spectrometry.
PubMed:Laser desorption time-of-flight mass spectrometric analysis of transferrin precipitated with antiserum: a unique simple method to identify molecular weight variants.
PubMed:The blocking effect of phenolic acid on N-nitrosomorpholine formation in vitro.
PubMed:High performance liquid chromatographic determination of phenolic acids in fruits and vegetables.
PubMed:Allelopathic compounds in leaves ofGliricidia sepium (Jacq.) kunth ex walp. and its effect onSorghum vulgare L.
PubMed:In situ reduction suitable for matrix-assisted laser desorption/ionization and liquid secondary ionization using tris(2-carboxyethyl)phosphine.
PubMed:Sinapic acid esters from Polygala virgata.
PubMed:An Arabidopsis mutant defective in the general phenylpropanoid pathway.
PubMed:Optimizing signal and mass resolution for matrix-assisted laser desorption utilizing a linear time-of-flight mass spectrometer.
PubMed:Growth inhibition and loss of virulence in cultures of Agrobacterium tumefaciens treated with acetosyringone.
PubMed:Substrate-assisted laser desorption of neutral peptide molecules.
PubMed:A compact time-of-flight mass spectrometer for the structural analysis of biological molecules using laser desorption.
PubMed:Matrix-assisted laser desorption/ionization of high-mass molecules by Fourier-transform mass spectrometry.
PubMed:Matrix-assisted laser desorption mass spectrometry of oligodeoxythymidylic acids.
PubMed:[Isolation and identification of antibiotic constituents of propolis from Henan].
PubMed:Fast protein sequence determination with matrix-assisted laser desorption and ionization mass spectrometry.
PubMed:Investigation of UV matrix-assisted laser desorption fourier transform mass spectrometry for peptides.
PubMed:Cinnamic acid derivatives as matrices for ultraviolet laser desorption mass spectrometry of proteins.
PubMed:[ON THE ANTHOCYANINS IN RED CABBAGE. II. ON THE COMPOSITION OF SINAPINIC ACID ESTER IN RUBROBRASSIN].
 
Notes:
a matrix for matrix-assisted laser desorption technique for protein mw determination; a constituent of propolis. A common constit. of plants and fruits
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